Elizabeth M. Camacho
Generating EQ-5D-3L health utility scores from the Edinburgh Postnatal Depression Scale: a perinatal mapping study
Camacho, Elizabeth M.; Shields, Gemma E.; Chew-Graham, Carolyn A.; Eisner, Emily; Gilbody, Simon; Littlewood, Elizabeth; McMillan, Dean; Watson, Kylie; Fearon, Pasco; Sharp, Deborah J.
Authors
Gemma E. Shields
Carolyn Chew-Graham c.a.chew-graham@keele.ac.uk
Emily Eisner
Simon Gilbody
Elizabeth Littlewood
Dean McMillan
Kylie Watson
Pasco Fearon
Deborah J. Sharp
Abstract
Background
Perinatal depression (PND) describes depression experienced by parents during pregnancy or in the first year after a baby is born. The EQ-5D instrument (a generic measure of health status) is not often collected in perinatal research, however disease-specific measures, such as the Edinburgh Postnatal Depression Scale (EPDS) are widely used. Mapping can be used to estimate generic health utility index values from disease-specific measures like the EPDS.
Objective
To develop a mapping algorithm to estimate EQ-5D utility index values from the EPDS.
Methods
Patient-level data from the BaBY PaNDA study (English observational cohort study) provided 1068 observations with paired EPDS and EQ-5D (3-level version; EQ-5D-3L) responses. We compared the performance of six alternative regression model types, each with four specifications of covariates (EPDS score and age: base, squared, and cubed). Model performance (ability to predict utility values) was assessed by ranking mean error, mean absolute error, and root mean square error. Algorithm performance in 3 external datasets was also evaluated.
Citation
Camacho, E. M., Shields, G. E., Chew-Graham, C. A., Eisner, E., Gilbody, S., Littlewood, E., …Sharp, D. J. (in press). Generating EQ-5D-3L health utility scores from the Edinburgh Postnatal Depression Scale: a perinatal mapping study. European Journal of Health Economics, https://doi.org/10.1007/s10198-023-01589-4
Journal Article Type | Article |
---|---|
Acceptance Date | Apr 11, 2023 |
Online Publication Date | Apr 24, 2023 |
Deposit Date | May 25, 2023 |
Journal | The European Journal of Health Economics |
Print ISSN | 1618-7598 |
Electronic ISSN | 1618-7601 |
Publisher | Springer Verlag |
Peer Reviewed | Peer Reviewed |
DOI | https://doi.org/10.1007/s10198-023-01589-4 |
Keywords | Health Policy; Economics, Econometrics and Finance (miscellaneous) |
Additional Information | Received: 30 January 2023; Accepted: 11 April 2023; First Online: 24 April 2023; : ; : All authors report no competing interests. |
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