All Outputs (27)

Towards Medical Diagnostics Using Hyperspectral X-ray scatter (2017)
Conference Proceeding
Greenwood, C., Rogers, K., Wilson, M., Lyburn, I., Evans, P., & Davies, G. (2017). Towards Medical Diagnostics Using Hyperspectral X-ray scatter.

This pilot study builds from a recent international, programme that showed, for the first time, the clinical value of new biomarkers to predict fracture risk in osteoporotic patients. The research indicated several potential, high impact routes towar... Read More about Towards Medical Diagnostics Using Hyperspectral X-ray scatter.

Towards new material biomarkers for fracture risk (2016)
Journal Article
Greenwood, C., Clement, J., Dicken, A., Evans, J., Lyburn, I., Martin, R., …Zioupos, P. (2016). Towards new material biomarkers for fracture risk. BONE, 93, 55-63. https://doi.org/10.1016/j.bone.2016.09.006

Osteoporosis is a prevalent bone condition, characterised by low bone mass and increased fracture risk. Currently, the gold standard for identifying osteoporosis and increased fracture risk is through quantification of bone mineral density (BMD) usin... Read More about Towards new material biomarkers for fracture risk.

Classification of fracture and non-fracture groups by analysis of coherent X-ray scatter (2016)
Journal Article
Dicken, A., Evans, J., Rogers, K., Stone, N., Greenwood, C., Godber, S., …Zioupos, P. (2016). Classification of fracture and non-fracture groups by analysis of coherent X-ray scatter. Scientific reports, 6, Article 29011. https://doi.org/10.1038/srep29011

Osteoporotic fractures present a significant social and economic burden, which is set to rise
commensurately with the aging population. Greater understanding of the physicochemical differences
between osteoporotic and normal conditions will facilit... Read More about Classification of fracture and non-fracture groups by analysis of coherent X-ray scatter.

The micro-architecture of human cancellous bone from fracture neck of femur patients in relation to the structural integrity and fracture toughness of the tissue (2015)
Journal Article
Greenwood, C., Clement, J., Dicken, A., Evans, J., Lyburn, I., Martin, R., …Zioupos, P. (2015). The micro-architecture of human cancellous bone from fracture neck of femur patients in relation to the structural integrity and fracture toughness of the tissue. Bone Reports, 3, 67 - 75. https://doi.org/10.1016/j.bonr.2015.10.001

Osteoporosis is clinically assessed from bone mineral density measurements using dual energy X-ray absorption (DXA). However, these measurements do not always provide an accurate fracture prediction, arguably because DXA does not grapple with ‘bone q... Read More about The micro-architecture of human cancellous bone from fracture neck of femur patients in relation to the structural integrity and fracture toughness of the tissue.

X-ray diffraction from bone employing annular and semi-annular beams (2015)
Journal Article
Dicken, A., Evans, J., Rogers, K., Stone, N., Greenwood, C., Godber, S., …Zioupos, P. (2015). X-ray diffraction from bone employing annular and semi-annular beams. Physics in Medicine and Biology, 60(15), 5803 - 5812. https://doi.org/10.1088/0031-9155/60/15/5803

There is a compelling need for accurate, low cost diagnostics to identify osteotissues that are associated with a high risk of fracture within an individual. To satisfy this requirement the quantification of bone characteristics such as ‘bone quality... Read More about X-ray diffraction from bone employing annular and semi-annular beams.

Energy-dispersive X-ray diffraction using an annular beam (2015)
Journal Article
Dicken, A. J., Evans, J. P. O., Rogers, K. D., Greenwood, C., Godber, S. X., Prokopiou, D., …Zioupos, P. (2015). Energy-dispersive X-ray diffraction using an annular beam. Optics express, 23(10), 13443-13454. https://doi.org/10.1364/oe.23.013443

We demonstrate material phase identification by measuring polychromatic diffraction spots from samples at least 20 mm in diameter and up to 10 mm thick with an energy resolving point detector. Within our method an annular X-ray beam in the form of a... Read More about Energy-dispersive X-ray diffraction using an annular beam.

Initial observations of dynamically heated bone: Initial observations of dynamically heated bone (2013)
Journal Article
Greenwood, C., Rogers, K., Beckett, S., & Clement, J. (2013). Initial observations of dynamically heated bone: Initial observations of dynamically heated bone. Crystal Research and Technology, 48(12), 1073-1082. https://doi.org/10.1002/crat.201300254

Sufferers of cystic fibrosis are at extremely high risk for contracting chronic lung infections. Over their lifetime, one bacterial strain in particular, Pseudomonas aeruginosa, becomes the dominant pathogen. Bacterial strains incur loss-of-function... Read More about Initial observations of dynamically heated bone: Initial observations of dynamically heated bone.