Addressing disparities in the long-term mortality of non-ST segment myocardial infarction (NSTEMI) patients according to the presence of diabetes mellitus: a nationwide cohort study

Cole, A; Weight, N; Mishra, S; Grapsa, J; Rutter, M; Siudak, Z; Moledina, S; Khunti, K; Mamas, M

doi:10.1093/eurheartj/ehae666.1533

Healthcare utilisation of 282,080 individuals with long COVID over two years: a multiple matched control, longitudinal cohort analysis. (2024)
Journal Article
Mu, Y., Dashtban, A., Mizani, M. A., Tomlinson, C., Mohamed, M., Ashworth, M., …Banerjee, A. (in press). Healthcare utilisation of 282,080 individuals with long COVID over two years: a multiple matched control, longitudinal cohort analysis. Journal of the Royal Society of Medicine, 13. https://doi.org/10.1177/01410768241288345

ObjectivesTo investigate healthcare utilisation and cost in individuals with long COVID (LC) at population level.DesignCase-control cohort analysis with multiple age-, sex-, ethnicity-, deprivation-, region- and comorbidity-matched control groups: (1... Read More about Healthcare utilisation of 282,080 individuals with long COVID over two years: a multiple matched control, longitudinal cohort analysis..

Sex differences in myocardial infarction care and outcomes: a longitudinal Scottish National Data-Linkage Study (2024)
Journal Article
Pana, T. A., Mamas, M. A., Myint, P. K., & Dawson, D. K. (in press). Sex differences in myocardial infarction care and outcomes: a longitudinal Scottish National Data-Linkage Study. European Journal of Preventive Cardiology, https://doi.org/10.1093/eurjpc/zwae333

Aims We investigate sex disparities in management and outcomes of myocardial infarction (MI) in contemporary practice in Scotland. Methods and results This was a longitudinal cohort study including all MI admissions aged 45-80 years across Scotland b... Read More about Sex differences in myocardial infarction care and outcomes: a longitudinal Scottish National Data-Linkage Study.

Drug‐Coated Balloons in In‐Stent Restenosis, a New Standard of Care or Yesterday's News? (2024)
Journal Article
Weight, N., & Mamas, M. A. (in press). Drug‐Coated Balloons in In‐Stent Restenosis, a New Standard of Care or Yesterday's News?. Journal of the American Heart Association, 13(23), https://doi.org/10.1161/jaha.124.038508

Routine measurement of cardiometabolic disease risk factors in primary care in England before, during, and after the COVID-19 pandemic: A population-based cohort study (2024)
Journal Article
Ho, F. K., Dale, C., Mizani, M. A., Bolton, T., Pearson, E. R., Valabhji, J., …Sattar, N. (in press). Routine measurement of cardiometabolic disease risk factors in primary care in England before, during, and after the COVID-19 pandemic: A population-based cohort study. PLoS Medicine, 21(11), Article e1004485. https://doi.org/10.1371/journal.pmed.1004485

Background: This study estimated to what extent the number of measurements of cardiometabolic risk factors (e.g., blood pressure, cholesterol, glycated haemoglobin) were impacted by the COVID-19 pandemic and whether these have recovered to expected l... Read More about Routine measurement of cardiometabolic disease risk factors in primary care in England before, during, and after the COVID-19 pandemic: A population-based cohort study.

Contemporary epidemiology of hospitalised heart failure with reduced versus preserved ejection fraction in England: a retrospective, cohort study of whole-population electronic health records. (2024)
Journal Article
Fletcher, R. A., Rockenschaub, P., Neuen, B. L., Walter, I. J., Conrad, N., Mizani, M. A., …Wood, A. M. (2024). Contemporary epidemiology of hospitalised heart failure with reduced versus preserved ejection fraction in England: a retrospective, cohort study of whole-population electronic health records. The Lancet, 9(11), e871-e885. https://doi.org/10.1016/S2468-2667%2824%2900215-9

Heart failure is common, complex, and often associated with coexisting chronic medical conditions and a high mortality. We aimed to assess the epidemiology of people admitted to hospital with heart failure with reduced ejection fraction (HFrEF) and h... Read More about Contemporary epidemiology of hospitalised heart failure with reduced versus preserved ejection fraction in England: a retrospective, cohort study of whole-population electronic health records..

Abstract 4138301: Burden of Hyperlipidemia, Cardiovascular Mortality, and COVID-19: A Retrospective-Cohort Analysis of US Data (2024)
Journal Article
Pham, H. N., Sainbayar, E., Ramzi, I., Olson, A., Alabagi, A., Soin, S., …Mamas, M. (2024). Abstract 4138301: Burden of Hyperlipidemia, Cardiovascular Mortality, and COVID-19: A Retrospective-Cohort Analysis of US Data. Circulation, 150(Suppl_1), https://doi.org/10.1161/circ.150.suppl_1.4138301

Background: Hyperlipidemia (HLD) is a major risk factor for cardiovascular disease (CVD). Little is known regarding temporal variation in CVD mortality related to HLD. The COVID-19 pandemic added complexity to factors influencing CVD mortality. Quest... Read More about Abstract 4138301: Burden of Hyperlipidemia, Cardiovascular Mortality, and COVID-19: A Retrospective-Cohort Analysis of US Data.

Abstract 4134687: Takotsubo Cardiomyopathy Complicating Stroke (2024)
Journal Article
Jang, S. H., Sposato, L., Choi, Y.-H., Geressu, A., Mamas, M., & Bagur, R. (2024). Abstract 4134687: Takotsubo Cardiomyopathy Complicating Stroke. Circulation, 150(Suppl_1), Article A4134687. https://doi.org/10.1161/circ.150.suppl_1.4134687

Background: There have been studies suggesting Takotsubo cardiomyopathy (TCM) as a potential complication following cerebrovascular accident (CVA), but the association, contributing factors, and prognosis significance have not been well-characterized... Read More about Abstract 4134687: Takotsubo Cardiomyopathy Complicating Stroke.

Burden of Hyperlipidemia, Cardiovascular Mortality, and COVID‐19: A Retrospective‐Cohort Analysis of US Data (2024)
Journal Article
Pham, H. N., Ibrahim, R., Sainbayar, E., Olson, A., Singh, A., Khanji, M. Y., …Mamas, M. A. (in press). Burden of Hyperlipidemia, Cardiovascular Mortality, and COVID‐19: A Retrospective‐Cohort Analysis of US Data. Journal of the American Heart Association, https://doi.org/10.1161/jaha.124.037381

Background Hyperlipidemia is a major cardiovascular disease (CVD) risk factor, but limited data on its mortality trends in CVD over time. We assessed annual hyperlipidemia‐related CVD mortality trends in the United States, including the COVID‐19 pand... Read More about Burden of Hyperlipidemia, Cardiovascular Mortality, and COVID‐19: A Retrospective‐Cohort Analysis of US Data.

Outcomes of 1.3 million patients undergoing percutaneous coronary intervention according to the presence of cancer and atrial fibrillation: a retrospective study. (2024)
Journal Article
Istanbuly, S., Matetić, A., Bang, V., Sharma, K., Golwala, H., Kheiri, B., …Mamas, M. A. (2024). Outcomes of 1.3 million patients undergoing percutaneous coronary intervention according to the presence of cancer and atrial fibrillation: a retrospective study. Croatian Medical Journal, 65(5), 405-416

To evaluate outcomes after percutaneous coronary intervention (PCI) in patients with cancer and atrial fibrillation (AF). Data of all adult discharges undergoing PCI between October 2015 and December 2018 were obtained from the National Inpatient Sam... Read More about Outcomes of 1.3 million patients undergoing percutaneous coronary intervention according to the presence of cancer and atrial fibrillation: a retrospective study..

Immediate Versus Staged Complete Revascularization for Patients With ST‐Segment–Elevation Myocardial Infarction and Multivessel Disease: A Network Meta‐Analysis of Randomized Trials (2024)
Journal Article
Elbadawi, A., Hamed, M., Gad, M., Elseidy, S. A., Barghout, M., Jneid, H., …Elgendy, I. Y. (in press). Immediate Versus Staged Complete Revascularization for Patients With ST‐Segment–Elevation Myocardial Infarction and Multivessel Disease: A Network Meta‐Analysis of Randomized Trials. Journal of the American Heart Association, 13(21), https://doi.org/10.1161/jaha.124.035535

Background The comparative outcomes with immediate, staged in‐hospital, and staged out‐of‐hospital complete revascularization for patients with ST‐segment–elevation myocardial infarction and multivessel disease remain unclear. Methods and Results An... Read More about Immediate Versus Staged Complete Revascularization for Patients With ST‐Segment–Elevation Myocardial Infarction and Multivessel Disease: A Network Meta‐Analysis of Randomized Trials.

Association of lifes essential 8 and mortality among adults with and without CVD (2024)
Journal Article
Kobo, O., Kaur, G., Gulati, M., & Mamas, M. (2024). Association of lifes essential 8 and mortality among adults with and without CVD. European Heart Journal, 45(Supplement_1), https://doi.org/10.1093/eurheartj/ehae666.2698

Background Differences in the American Heart Association’s Life’s Essential 8 (LE8) score and its association with mortality based on the presence of clinically prevalent cardiovascular disease (CVD) has not been assessed previously. Methods Data fro... Read More about Association of lifes essential 8 and mortality among adults with and without CVD.

Insights into the reporting of major adverse cardiovascular events in coronary artery disease trials (2024)
Journal Article
Lee, E., Tan, B., Chin, Y. H., Chan, Y. H., Ong, J., Goh, R. S. J., …Mamas, M. A. (2024). Insights into the reporting of major adverse cardiovascular events in coronary artery disease trials. European Heart Journal, 45(Supplement_1), https://doi.org/10.1093/eurheartj/ehae666.1556

Background and Purpose Major adverse cardiovascular event (MACE) is one of the most used composite outcomes in coronary artery disease (CAD) trials, though its lack of a standardised definition has led to ambiguity and challenges in its interpretatio... Read More about Insights into the reporting of major adverse cardiovascular events in coronary artery disease trials.

Sex differences in secondary prevention and outcomes post-myocardial infarction in Scotland (2024)
Journal Article
Pana, T., Mamas, M. A., Myint, P. K., & Dawson, D. (2024). Sex differences in secondary prevention and outcomes post-myocardial infarction in Scotland. European Heart Journal, 45(Supplement_1), https://doi.org/10.1093/eurheartj/ehae666.2781

Background Sex differences in outcomes after myocardial infarction (MI) are of increasing interest. Differential receipt of evidence-based treatments may contribute to such disparities. Purpose In this study, we investigate sex differences in the bur... Read More about Sex differences in secondary prevention and outcomes post-myocardial infarction in Scotland.

Sex sifferences in lifes essential eight and its association with mortality among adults without known CVD (2024)
Journal Article
Kobo, O., Kaur, G., Gulati, M., & Mamas, M. (2024). Sex sifferences in lifes essential eight and its association with mortality among adults without known CVD. European Heart Journal, 45(Supplement_1), https://doi.org/10.1093/eurheartj/ehae666.3071

Background The American Heart Association’s Life’s Essential 8 (LE8) score is a helpful tool to quantify cardiovascular health (CVH) metrics. Sex differences in relation to LE8 and its association with mortality are not known. Methods The National He... Read More about Sex sifferences in lifes essential eight and its association with mortality among adults without known CVD.

A practical risk score for prediction of 6-month mortality in patients with acute heart failure: CHAM2P2 (2024)
Journal Article
Todd, F., Wong, C., Gogola, L., Skyrme-Jones, A., Ghosh, A. K., Garg, P., …Dastidar, A. (2024). A practical risk score for prediction of 6-month mortality in patients with acute heart failure: CHAM2P2. European Heart Journal, 45(Supplement_1), https://doi.org/10.1093/eurheartj/ehae666.1190

Background Admission with acute heart failure carries a poor prognosis. Multiple predictive risk scores exist in heart failure presentation, however the utility of these scores in acute heart failure setting among older adults is limited. Aim The pur... Read More about A practical risk score for prediction of 6-month mortality in patients with acute heart failure: CHAM2P2.

Myocardial infarction risk across cancer subtypes - nationwide registry study (2024)
Journal Article
Shanmuganathan, J., Jacobsen, P. A. J., Schou, M. S., Torp Pedersen, C. T. P., Poulsen, L., Polcwiartek, C. B. P., …Kragholm, K. K. (2024). Myocardial infarction risk across cancer subtypes - nationwide registry study. European Heart Journal, 45(Supplement_1), https://doi.org/10.1093/eurheartj/ehae666.1551

Background Progress in cancer treatments have significantly improved patient outcomes, leading to increased survival rates. However, patients with cancer continue to have higher rates of cardiovascular events an area that has traditionally not receiv... Read More about Myocardial infarction risk across cancer subtypes - nationwide registry study.

Ischemic and bleeding risk after ST-segment elevated myocardial infarction in patients with active cancer (2024)
Journal Article
Dafaalla, M., Costa, F., Jia, H., Wijeysundera, H., Rashid, M., Graham, M., …Mamas, M. (2024). Ischemic and bleeding risk after ST-segment elevated myocardial infarction in patients with active cancer. European Heart Journal, 45(Supplement_1), https://doi.org/10.1093/eurheartj/ehae666.2633

Background Treatment of patients with cancer presenting with ST-elevation myocardial infarction (STEMI) is complex given the increased risk of both thrombotic and major bleeding complications. We evaluated the risk of major bleeding and re-infarction... Read More about Ischemic and bleeding risk after ST-segment elevated myocardial infarction in patients with active cancer.

Mechanical thrombectomy is associated with worse outcomes in infective endocarditis: a retrospective cohort study (2024)
Journal Article
Barlas, R., Pana, T., Myint, P., & Mamas, M. A. (2024). Mechanical thrombectomy is associated with worse outcomes in infective endocarditis: a retrospective cohort study. European Heart Journal, 45(Supplement_1), https://doi.org/10.1093/eurheartj/ehae666.1969

Background Acute Ischaemic stroke (AIS) is a common complication in infective endocarditis (IE) and associated is with high mortality. There is a paucity of data evaluating mechanical thrombectomy (MT) in patients with AIS secondary to IE. Our retros... Read More about Mechanical thrombectomy is associated with worse outcomes in infective endocarditis: a retrospective cohort study.

Ethnic disparity in the care and management of non-ST-segment elevation myocardial infarction and its impact on short-term and long-term survival: a long-term study of a national registry (2024)
Journal Article
Yera, H., Weight, N., Moledina, S. M., & Mamas, M. A. (2024). Ethnic disparity in the care and management of non-ST-segment elevation myocardial infarction and its impact on short-term and long-term survival: a long-term study of a national registry. European Heart Journal, 45(Supplement_1), https://doi.org/10.1093/eurheartj/ehae666.1559

Background Previous examination of data from the United Kingdom indicates no apparent ethnic disparity in the treatment of patients hospitalised with non-ST-segment elevation myocardial infarction (NSTEMI). However, it remains uncertain whether this... Read More about Ethnic disparity in the care and management of non-ST-segment elevation myocardial infarction and its impact on short-term and long-term survival: a long-term study of a national registry.

Addressing disparities in the long-term mortality of non-ST segment myocardial infarction (NSTEMI) patients according to the presence of diabetes mellitus: a nationwide cohort study (2024)
Journal Article
Cole, A., Weight, N., Mishra, S., Grapsa, J., Rutter, M., Siudak, Z., …Mamas, M. (2024). Addressing disparities in the long-term mortality of non-ST segment myocardial infarction (NSTEMI) patients according to the presence of diabetes mellitus: a nationwide cohort study. European Heart Journal, 45(Supplement_1), https://doi.org/10.1093/eurheartj/ehae666.1533

Background Diabetes mellitus (DM) is an important risk factor for non−ST segment elevation myocardial infarction (NSTEMI). How DM is related to management and longer-term clinical outcomes in contemporary NSTEMI cohorts is not well described. Methods... Read More about Addressing disparities in the long-term mortality of non-ST segment myocardial infarction (NSTEMI) patients according to the presence of diabetes mellitus: a nationwide cohort study.

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