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All Outputs (150)

Association of Smoking and Young Cryptogenic Ischemic Stroke (2025)
Journal Article
Ferdinand, P., Bajpai, R., Von Sarnowski, B., Ylikotila, P., Zedde, M., Sarkanen, T., …Roffe, C. (2025). Association of Smoking and Young Cryptogenic Ischemic Stroke. Neurology Open Access, 1(1), 1-9. https://doi.org/10.1212/wn9.0000000000000003

Background and Objectives
The incidence of ischemic stroke in the young is increasing and driven by cryptogenic strokes. Smoking is a well-documented risk factor with a high prevalence in young ischemic strokes. We sought to determine the associatio... Read More about Association of Smoking and Young Cryptogenic Ischemic Stroke.

CLINICAL AND COST-EFFECTIVENESS OF A PERSONALISED GUIDED CONSULTATION VERSUS USUAL PHYSIOTHERAPY CARE IN PEOPLE PRESENTING WITH SHOULDER PAIN: A PROTOCOL FOR THE PANDA-S CLUSTER RANDOMISED CONTROLLED TRIAL AND PROCESS EVALUATION (2025)
Working Paper
A Harrisson, S., Myers, H., Wynne Jones, G., Bajpai, R., Bratt, C., Burton, C., …A Van der Windt, D. CLINICAL AND COST-EFFECTIVENESS OF A PERSONALISED GUIDED CONSULTATION VERSUS USUAL PHYSIOTHERAPY CARE IN PEOPLE PRESENTING WITH SHOULDER PAIN: A PROTOCOL FOR THE PANDA-S CLUSTER RANDOMISED CONTROLLED TRIAL AND PROCESS EVALUATION

Introduction Musculoskeletal shoulder pain is a common reason for people to be treated in physiotherapy services, but diagnosis can be difficult and often does not guide treatment or predict outcome. People with shoulder pain cite a need for clear in... Read More about CLINICAL AND COST-EFFECTIVENESS OF A PERSONALISED GUIDED CONSULTATION VERSUS USUAL PHYSIOTHERAPY CARE IN PEOPLE PRESENTING WITH SHOULDER PAIN: A PROTOCOL FOR THE PANDA-S CLUSTER RANDOMISED CONTROLLED TRIAL AND PROCESS EVALUATION.

Machine learning model for predicting DIBH non-eligibility in left-sided breast cancer radiotherapy: Development, validation and clinical impact analysis. (2025)
Journal Article
Chufal, K. S., Ahmad, I., Miller, A. A., Bajpai, R., Dwivedi, A., Dwivedi, A., …Gairola, M. (in press). Machine learning model for predicting DIBH non-eligibility in left-sided breast cancer radiotherapy: Development, validation and clinical impact analysis. Radiotherapy and Oncology, 205, Article 110764. https://doi.org/10.1016/j.radonc.2025.110764

Multi-day assessments accurately identify patients with left-sided breast cancer who are ineligible for irradiation in Deep Inspiration Breath Hold (DIBH) and minimise on-couch treatment time in those who are eligible. The challenge of implementing m... Read More about Machine learning model for predicting DIBH non-eligibility in left-sided breast cancer radiotherapy: Development, validation and clinical impact analysis..

Family-based sexual health intervention for adolescents; A systematic review and meta-analysis (2024)
Journal Article
Mataraarachchi, D., Shepherd, T., Ariyadasa, G., Bajpai, R., Corp, N., & Paudyal, P. (2024). Family-based sexual health intervention for adolescents; A systematic review and meta-analysis. European Journal of Public Health, 34(Supplement_3), https://doi.org/10.1093/eurpub/ckae144.1057

Background Family-based interventions are important in promoting adolescent sexual health outcomes. However, the effectiveness of these interventions in promoting adolescent sexual and reproductive health (ASRH) in Lower and middle-income countries (... Read More about Family-based sexual health intervention for adolescents; A systematic review and meta-analysis.

Exploring online public survey lifestyle datasets with statistical analysis, machine learning and semantic ontology (2024)
Journal Article
Chatterjee, A., Riegler, M. A., Johnson, M. S., Das, J., Pahari, N., Ramachandra, R., …Bajpai, R. (2024). Exploring online public survey lifestyle datasets with statistical analysis, machine learning and semantic ontology. Scientific Reports, 14(1), 1-24. https://doi.org/10.1038/s41598-024-74539-6

Lifestyle diseases significantly contribute to the global health burden, with lifestyle factors playing a crucial role in the development of depression. The COVID-19 pandemic has intensified many determinants of depression. This study aimed to identi... Read More about Exploring online public survey lifestyle datasets with statistical analysis, machine learning and semantic ontology.

Systematic review of prognostic factors for poor outcome in people living with dementia that can be determined from primary care medical records (2024)
Journal Article
Marshall, M., Jordan, J. L., Bajpai, R., Nimmons, D., Smith, T. M., Campbell, P., & Jordan, K. P. (2024). Systematic review of prognostic factors for poor outcome in people living with dementia that can be determined from primary care medical records. BMC Geriatrics, 24(1), Article 801. https://doi.org/10.1186/s12877-024-05389-0

Background: Dementia has a major impact on individuals, their families and caregivers, and wider society. Some individuals experience a faster decline of their function and health compared to others. The objective of this systematic review was to det... Read More about Systematic review of prognostic factors for poor outcome in people living with dementia that can be determined from primary care medical records.

Community-based complex interventions to sustain independence in older people, stratified by frailty: a systematic review and network meta-analysis (2024)
Journal Article
Crocker, T. F., Lam, N., Ensor, J., Jordão, M., Bajpai, R., Bond, M., …Clegg, A. (2024). Community-based complex interventions to sustain independence in older people, stratified by frailty: a systematic review and network meta-analysis. Health Technology Assessment, 28(48), 224. https://doi.org/10.3310/HNRP2514

Background
Sustaining independence is important for older people, but there is insufficient guidance about which community health and care services to implement.

Objectives
To synthesise evidence of the effectiveness of community services to sus... Read More about Community-based complex interventions to sustain independence in older people, stratified by frailty: a systematic review and network meta-analysis.

Identification of variables and development of a prediction model for DIBH eligibility in left-sided breast cancer radiotherapy: a prospective cohort study with temporal validation (2024)
Journal Article
Ahmad, I., Chufal, K. S., Miller, A. A., Bajpai, R., Umesh, P., Sokhal, B. S., …Gairola, M. (in press). Identification of variables and development of a prediction model for DIBH eligibility in left-sided breast cancer radiotherapy: a prospective cohort study with temporal validation. Radiation Oncology, 19(1), Article 115. https://doi.org/10.1186/s13014-024-02512-8

Objective
To identify variables associated with a patients’ ability to reproducibly hold their breath for deep-inspiration breath-hold (DIBH) radiotherapy (RT) and to develop a predictive model for DIBH eligibility.

Methods
This prospective, sin... Read More about Identification of variables and development of a prediction model for DIBH eligibility in left-sided breast cancer radiotherapy: a prospective cohort study with temporal validation.

The Relationship Between Obesity and Patient-Reported Outcome Measures in People with Polymyalgia Rheumatica (2024)
Journal Article
Scott, I. C., Bajpai, R., Hider, S. L., Helliwell, T., Mallen, C. D., & Muller, S. (in press). The Relationship Between Obesity and Patient-Reported Outcome Measures in People with Polymyalgia Rheumatica. Rheumatology Advances in Practice, 8(3), Article rkae081. https://doi.org/10.1093/rap/rkae081

Objective
To examine the association between obesity and patient-reported outcomes measures (PROMs) in a primary care-based cohort of people with polymyalgia rheumatica (PMR).

Methods
The PMR Cohort Study recruited people with incident PMR from... Read More about The Relationship Between Obesity and Patient-Reported Outcome Measures in People with Polymyalgia Rheumatica.

Development of the Community-based complex Interventions to sustain Independence in Older People (CII-OP) typology: a qualitative synthesis of interventions in randomised controlled trials (2024)
Journal Article
Crocker, T. F., Jordão, M., Lam, N., Ramiz, R., Mirza, L., Patel, I., …Walford, R. (2024). Development of the Community-based complex Interventions to sustain Independence in Older People (CII-OP) typology: a qualitative synthesis of interventions in randomised controlled trials. Age and ageing, 53(5), 1-13. https://doi.org/10.1093/ageing/afae102

Introduction Community-based services to sustain independence for older people have varying configurations. A typology of these interventions would improve service provision and research by providing conceptual clarity and enabling the identification... Read More about Development of the Community-based complex Interventions to sustain Independence in Older People (CII-OP) typology: a qualitative synthesis of interventions in randomised controlled trials.

P082 Nephrolithiasis associated with uricosuric therapies for the treatment of gout: a systematic review (2024)
Presentation / Conference
Dahanayake, C., Bajpai, R., Jordan, K. M., Lambie, M., & Roddy, E. (2024, April). P082 Nephrolithiasis associated with uricosuric therapies for the treatment of gout: a systematic review. Poster presented at British Society for Rheumatology Annual Conference 2024

Background/Aims
Uric acid nephrolithiasis is a recognised side-effect of uricosuric therapies and a contraindication to their use. The objective of this systematic review was to assess the incidence and risk of nephrolithiasis in people with gout re... Read More about P082 Nephrolithiasis associated with uricosuric therapies for the treatment of gout: a systematic review.

Long-term outcomes of COVID-19 infection in children and young people: a systematic review and meta-analysis [version 1; peer review: awaiting peer review] (2024)
Journal Article
Twohig, H., Bajpai, R., Corp, N., Faux-Nightingale, A., Mallen, C., Robinson, T., …Burton, C. (2024). Long-term outcomes of COVID-19 infection in children and young people: a systematic review and meta-analysis [version 1; peer review: awaiting peer review]. NIHR Open Research, 4(22), https://doi.org/10.3310/nihropenres.13549.1

Background
Children and young people (CYP) may experience prolonged symptoms following COVID-19, commonly termed ‘Long-COVID’. The characteristics of Long-COVID in CYP are unclear, as are the sequalae of acute COVID-19. We aimed to systematically sy... Read More about Long-term outcomes of COVID-19 infection in children and young people: a systematic review and meta-analysis [version 1; peer review: awaiting peer review].

Prognostic factors for colchicine prophylaxis-related adverse events when initiating allopurinol for gout: retrospective cohort study (2024)
Journal Article
Bajpai, R., Partington, R., Muller, S., Forrester, H., Mallen, C. D., Clarson, L., …Roddy, E. (2024). Prognostic factors for colchicine prophylaxis-related adverse events when initiating allopurinol for gout: retrospective cohort study. Rheumatology, Article keae229. https://doi.org/10.1093/rheumatology/keae229

Objectives
Colchicine is commonly used to prevent flares when starting urate-lowering therapy for gout. Patients with gout are frequently concurrently prescribed other medications (such as statins) that may interact with colchicine, increasing the r... Read More about Prognostic factors for colchicine prophylaxis-related adverse events when initiating allopurinol for gout: retrospective cohort study.

Identifying carers in general practice (STATUS QUO): a multicentre, cross-sectional study in England (2024)
Journal Article
Lawton, S., Mallen, C., Hussain, Z., Bajpai, R., Muller, S., Holmstrom, C., …Helliwell, T. (2024). Identifying carers in general practice (STATUS QUO): a multicentre, cross-sectional study in England. BMJ Open, 14(4), Article e083816. https://doi.org/10.1136/bmjopen-2023-083816

Objectives: To determine General Practice (GP) recording of carer status and the number of patients self-identifying as carers, while self-completing an automated check-in screen prior to a GP consultation.

Design: A descriptive cross-sectional st... Read More about Identifying carers in general practice (STATUS QUO): a multicentre, cross-sectional study in England.

Risk of adverse outcomes during gabapentinoid therapy and factors associated with increased risk in UK primary care using the clinical practice research datalink: a cohort study (2024)
Journal Article
Muller, S., Bailey, J., Bajpai, R., Helliwell, T., Harrisson, S. A., Whittle, R., …Ashworth, J. (2024). Risk of adverse outcomes during gabapentinoid therapy and factors associated with increased risk in UK primary care using the clinical practice research datalink: a cohort study. PAIN, https://doi.org/10.1097/j.pain.0000000000003239

Growing evidence from pharmacovigilance data and postmortem toxicology reports highlights the misuse potential of gabapentinoids. This study aimed to investigate the risk of serious adverse outcomes (drug misuse, overdose, major trauma), and their ri... Read More about Risk of adverse outcomes during gabapentinoid therapy and factors associated with increased risk in UK primary care using the clinical practice research datalink: a cohort study.

Cardiac markers in left-sided breast cancer patients receiving adjuvant radiotherapy: a prospective study (2024)
Journal Article
Chufal, K., Ahmad, I., Prakash, A., Miller, A., Umesh, P., Koul, V., …Gairola, M. (in press). Cardiac markers in left-sided breast cancer patients receiving adjuvant radiotherapy: a prospective study. Cardio-Oncology, 10(1), Article 21. https://doi.org/10.1186/s40959-024-00225-1

Objectives
To investigate the association between radiotherapy (RT) and cardiac biomarkers in women with left-sided breast cancer.

Methods
This prospective observational study recruited patients with stage I-III left-sided breast cancer without... Read More about Cardiac markers in left-sided breast cancer patients receiving adjuvant radiotherapy: a prospective study.

Is it too early to recommend local treatment in oligometastatic NSCLC: a plea for equipoise (2024)
Journal Article
Ahmad, I., Chufal, K. S., Miller, A. A., Bajpai, R., Umesh, P., Dawer, A., …Gairola, M. (in press). Is it too early to recommend local treatment in oligometastatic NSCLC: a plea for equipoise. British Journal of Radiology, 97(1157), 913-919. https://doi.org/10.1093/bjr/tqae068

Oligometastatic Non-Small Cell Lung cancer (OMD NSCLC) has been proposed to bridge the spectrum between non-metastatic to widely metastatic states and is perceived as an opportunity for potential cure if removed. Twelve clinical trials on local treat... Read More about Is it too early to recommend local treatment in oligometastatic NSCLC: a plea for equipoise.