All Outputs (395)

Missing Information About Study Funding (2018)
Journal Article
Mason, K. J., Barker, J. N., Smith, C. H., Hampton, P. J., Lunt, M., McElhone, K., Warren, R. B., Yiu, Z. Z., Griffiths, C. E., Burden, A. D., & Study Group, T. B. (2018). Missing Information About Study Funding. JAMA Dermatology, 154(7), 852. https://doi.org/10.1001/jamadermatol.2018.2319

In the Original Investigation titled “Comparison of Drug Discontinuation, Effectiveness, and Safety Between Clinical Trial Eligible And Ineligible Patients in BADBIR,”1 published online March 28, 2018, there was information omitted regarding study fu... Read More about Missing Information About Study Funding.

Do frailty measures improve prediction of mortality and morbidity following transcatheter aortic valve implantation? An analysis of the UK TAVI registry (2018)
Journal Article
Mamas. (2018). Do frailty measures improve prediction of mortality and morbidity following transcatheter aortic valve implantation? An analysis of the UK TAVI registry. Cardiovascular Medicine, https://doi.org/10.1136/bmjopen-2018-022543

Objectives
Previous studies indicate frailty to be associated with poor outcomes following transcatheter aortic valve implantation (TAVI), but there is limited evidence from multicentre registries. The aim was to investigate the independent associat... Read More about Do frailty measures improve prediction of mortality and morbidity following transcatheter aortic valve implantation? An analysis of the UK TAVI registry.

Percutaneous coronary intervention of saphenous vein grafts: where do we stand? (2018)
Journal Article
Bulluck, H., Bagur, R., & Mamas, M. A. (2018). Percutaneous coronary intervention of saphenous vein grafts: where do we stand?. EuroIntervention, 14(2), 142-143. https://doi.org/10.4244/EIJV14I2A22

Saphenous vein grafts (SVG) are known to be more susceptible to accelerated atherosclerosis than native coronary arteries1. Accelerated atherosclerosis in SVG develops from resident foam cells, which then undergo apoptosis to form necrotic cores1. Th... Read More about Percutaneous coronary intervention of saphenous vein grafts: where do we stand?.

NATIONAL ANALYSIS OF RARE BUT CATASTROPHIC BLEEDING COMPLICATIONS AFTER PERCUTANEOUS CORONARY INTERVENTIONS: INSIGHTS FROM THE BRITISH CARDIOVASCULAR INTERVENTION SOCIETY DATABASE (2018)
Journal Article
Kwok, C. S., Kontopantelis, E., Ludman, P., de Belder, M., & Mamas, M. (2018). NATIONAL ANALYSIS OF RARE BUT CATASTROPHIC BLEEDING COMPLICATIONS AFTER PERCUTANEOUS CORONARY INTERVENTIONS: INSIGHTS FROM THE BRITISH CARDIOVASCULAR INTERVENTION SOCIETY DATABASE. Heart, 104, A53-A53. https://doi.org/10.1136/heartjnl-2018-BCS.59

Background Major bleeding is a recognised complication after PCI. This study aims to evaluate the incidence, trends over time, predictors and prognostic significance of intracranial, gastrointestinal and retroperitoneal bleeding after PCI.

Methods... Read More about NATIONAL ANALYSIS OF RARE BUT CATASTROPHIC BLEEDING COMPLICATIONS AFTER PERCUTANEOUS CORONARY INTERVENTIONS: INSIGHTS FROM THE BRITISH CARDIOVASCULAR INTERVENTION SOCIETY DATABASE.

Gestational diabetes mellitus: are mothers being followed-up? A retrospective study (2018)
Presentation / Conference
Ward, R., Hanna, F. W., Shelley-Hitchen, A., Hodgson, E., Heald, A., Fryer, A. A., & Duff, C. J. (2018, June). Gestational diabetes mellitus: are mothers being followed-up? A retrospective study

Background Women with gestational diabetes (GDM) have an elevated risk of developing type 2 diabetes (T2DM). NICE Guidance recommends women who develop GDM are screened 6 weeks post-partum and annually thereafter.

Aim To evaluate conformity to gui... Read More about Gestational diabetes mellitus: are mothers being followed-up? A retrospective study.

Risk factors for the onset of musculoskeletal pain in children and adolescents (2018)
Thesis
Andreucci, A. Risk factors for the onset of musculoskeletal pain in children and adolescents. (Thesis). Keele University. https://keele-repository.worktribe.com/output/411391

Background

Musculoskeletal pain is a major burden on society. Research in adults has identified risk factors associated with musculoskeletal pain onset, however at present evidence for risk factors in children and adolescents is limited.

Aims... Read More about Risk factors for the onset of musculoskeletal pain in children and adolescents.

Structure and function of the visual pathway in demyelinating optic neuropathy (2018)
Thesis
Nayak, D. Structure and function of the visual pathway in demyelinating optic neuropathy. (Thesis). Keele University. https://keele-repository.worktribe.com/output/411393

Introduction: Multiple sclerosis is a disabling disease with impact on the social, financial and occupational life of an individual. Diagnosis of Multiple sclerosis even with the McDonald criteria, sometimes can take many years, by which time the pat... Read More about Structure and function of the visual pathway in demyelinating optic neuropathy.

Primary care decision-making for shoulder pain: identifying treatment effect moderators using clinical expertise (2018)
Thesis
McRobert, C. Primary care decision-making for shoulder pain: identifying treatment effect moderators using clinical expertise. (Thesis). Keele University. https://keele-repository.worktribe.com/output/411441

Background
Shoulder pain is a common, costly condition with variable prognosis. Commonly used treatments for shoulder pain in primary care include: (i) advice & analgesia, (ii) exercise and/or manual therapy, and (iii) corticosteroid injection. Curr... Read More about Primary care decision-making for shoulder pain: identifying treatment effect moderators using clinical expertise.

Action research: towards excellence in teaching, assessment and feedback for clinical consultation skills (2018)
Thesis
Lefroy, J. Action research: towards excellence in teaching, assessment and feedback for clinical consultation skills. (Thesis). Keele University. https://keele-repository.worktribe.com/output/411453

Background
Consultation skills are the core competencies required at graduation of the doctor as a practitioner. Every medical school has its own system of teaching and assessing consultation skills. These are generally amalgams of previous curricu... Read More about Action research: towards excellence in teaching, assessment and feedback for clinical consultation skills.

Evidence based hydrotherapy: a community of practice approach (2018)
Thesis
Smith, P. J. Evidence based hydrotherapy: a community of practice approach. (Thesis). Keele University. https://keele-repository.worktribe.com/output/418140

Health Care Professionals and patients report that hydrotherapy is valuable in managing inflammatory arthritis and musculoskeletal pain. However, clinical services are increasingly required to justify the clinical and cost effectiveness of hydrothera... Read More about Evidence based hydrotherapy: a community of practice approach.

Pre-operative use of aspirin in patients undergoing coronary artery bypass grafting: a systematic review and updated meta-analysis (2018)
Journal Article
Solo, K., Lavi, S., Choudhury, T., Martin, J., Nevis, I. F., Kwok, C. S., Kotronias, R. A., Nishina, N., Sponga, S., Ayan, D., Mamas, M. A., & Bagur, R. (2018). Pre-operative use of aspirin in patients undergoing coronary artery bypass grafting: a systematic review and updated meta-analysis. Journal of thoracic disease, 10(6), 3444-+. https://doi.org/10.21037/jtd.2018.05.187

Background: Aspirin therapy improves saphenous vein graft (SVG) patency in patients undergoing coronary artery bypass graft (CABG), however, its use in the pre-operative period remains controversial. Therefore, we conducted a systematic review and me... Read More about Pre-operative use of aspirin in patients undergoing coronary artery bypass grafting: a systematic review and updated meta-analysis.

Measurement error and timing of predictor values for multivariable risk prediction models are poorly reported (2018)
Journal Article
Whittle, R., Peat, G., Belcher, J., Collins, G. S., & Riley, R. D. (2018). Measurement error and timing of predictor values for multivariable risk prediction models are poorly reported. Journal of Clinical Epidemiology, 102, 38-49. https://doi.org/10.1016/j.jclinepi.2018.05.008

Objective
Measurement error in predictor variables may threaten the validity of clinical prediction models. We sought to evaluate the possible extent of the problem. A secondary objective was to examine whether predictors are measured at the intende... Read More about Measurement error and timing of predictor values for multivariable risk prediction models are poorly reported.

Predicting surgical intervention in patients presenting with carpal tunnel syndrome in primary care (2018)
Journal Article
Burton, C. L., S Chesterton, L., Chen, Y., & Van Der Windt, D. (2018). Predicting surgical intervention in patients presenting with carpal tunnel syndrome in primary care. Clinical Epidemiology, 739 - 748. https://doi.org/10.2147/CLEP.S154409

Purpose: Carpal tunnel syndrome (CTS) is a symptomatic compression neuropathy of the median nerve. This study investigated the value of candidate prognostic factors (PFs) in predicting carpal tunnel release surgery. Patients and methods: This is a re... Read More about Predicting surgical intervention in patients presenting with carpal tunnel syndrome in primary care.

Comparative Effectiveness of Treatment Options for Plantar Heel Pain: A Systematic Review with Network Meta-Analysis (2018)
Journal Article
Babatunde, Van Der Windt, Roddy, & Thomas. (2018). Comparative Effectiveness of Treatment Options for Plantar Heel Pain: A Systematic Review with Network Meta-Analysis. British Journal of Sports Medicine, 53(3), 1-14. https://doi.org/10.1136/bjsports-2017-098998

Objective
To evaluate the comparative effectiveness of current treatment options for plantar heel pain (PHP).

Design
Systematic review and network meta-analysis (NMA).

Data sources
Medline, EMBASE, CINAHL, AMED, PEDro, Cochrane Database, Web... Read More about Comparative Effectiveness of Treatment Options for Plantar Heel Pain: A Systematic Review with Network Meta-Analysis.

Metabolic risk factors and the incidence and progression of radiographic hand osteoarthritis: a population-based cohort study (2018)
Journal Article
Marshall, M., Peat, G., Nicholls, E., Myers, H. L., Mamas, M. A., & Van Der Windt, D. A. (in press). Metabolic risk factors and the incidence and progression of radiographic hand osteoarthritis: a population-based cohort study. Scandinavian Journal of Rheumatology, 48(1), 52-63. https://doi.org/10.1080/03009742.2018.1459831

OBJECTIVE: To determine whether selected metabolic factors are associated with greater amounts of radiographic hand osteoarthritis (OA) incidence and progression. METHODS: The study identified 706 adults, aged 50-69 years, with hand pain and hand rad... Read More about Metabolic risk factors and the incidence and progression of radiographic hand osteoarthritis: a population-based cohort study.

Long-term conditions and the National Diabetes Audit (2018)
Journal Article
Heald, A., Stedman, M., Farman, S., Fryer, A., Bailey, S., & Gadsby, R. (2018). Long-term conditions and the National Diabetes Audit. British Journal of General Practice (BJGP), 68(672), 320.2-320. https://doi.org/10.3399/bjgp18x697637

The management of long-term conditions1 in primary care has hit the headlines thanks to a report from the Academy of Medical Sciences,2 which highlighted the clustering of different physical and mental health conditions in a single patient, and estim... Read More about Long-term conditions and the National Diabetes Audit.

Comparative Effectiveness of Treatment Options for Plantar Heel Pain: A Systematic Review with Network Meta-Analysis (2018)
Journal Article
Babatunde, O., Legha, A., Littlewood, C., Chesterton, L. S., Thomas, M. J., B Menz, H., Van Der Windt, D., & Roddy, E. (2018). Comparative Effectiveness of Treatment Options for Plantar Heel Pain: A Systematic Review with Network Meta-Analysis. British Journal of Sports Medicine, 53(3), https://doi.org/10.1136/bjsports-2017-098998

Objective
To evaluate the comparative effectiveness of current treatment options for plantar heel pain (PHP).

Design
Systematic review and network meta-analysis (NMA).

Data Sources
Medline, EMBASE, CINAHL, AMED, PEDro, Cochrane Database, We... Read More about Comparative Effectiveness of Treatment Options for Plantar Heel Pain: A Systematic Review with Network Meta-Analysis.

Noninvasive imaging of nanoparticle-labeled transplant populations within polymer matrices for neural cell therapy (2018)
Journal Article
Tickle, J. A., Poptani, H., Taylor, A., & Chari, D. M. (2018). Noninvasive imaging of nanoparticle-labeled transplant populations within polymer matrices for neural cell therapy. Nanomedicine, 13(11), 1333-1348. https://doi.org/10.2217/nnm-2017-0347

Aim: To develop a 3D neural cell construct for encapsulated delivery of transplant cells; develop hydrogels seeded with magnetic nanoparticle (MNP)-labeled cells suitable for cell tracking by MRI. Materials & methods: Astrocytes were exogenously labe... Read More about Noninvasive imaging of nanoparticle-labeled transplant populations within polymer matrices for neural cell therapy.

THE RISK OF KC IN PSORIASIS PATIENTS RECEIVING BIOLOGICS COMPARED TO CONVENTIONAL SYSTEMIC THERAPIES (2018)
Presentation / Conference
Mason, K. (2018, June). THE RISK OF KC IN PSORIASIS PATIENTS RECEIVING BIOLOGICS COMPARED TO CONVENTIONAL SYSTEMIC THERAPIES. Poster presented at 5th World Psoriasis & Psoriatic Arthritis Conference, Stockholm, Sweden

Introduction: Whether psoriasis patients exposed to biologic
therapies have an elevated risk of keratinocyte carcinoma (KC),
including basal cell carcinoma (BCC) or cutaneous squamous cell
carcinoma (cSCC) remains uncertain. Objective:The aim of t... Read More about THE RISK OF KC IN PSORIASIS PATIENTS RECEIVING BIOLOGICS COMPARED TO CONVENTIONAL SYSTEMIC THERAPIES.

Early Clinical Outcomes, Patterns of Failure, and Acute Haematologic Toxicity of Image-Guided Volumetric Modulated Arc Therapy (IG-VMAT) in the Definitive Treatment of Locally Advanced Carcinoma Cervix (2018)
Journal Article
Ahmad, I., Chufal, K. S., Bashir, I., Bhatt, C. P., Bajpai, R., Sharma, L., & Rathour, S. (2018). Early Clinical Outcomes, Patterns of Failure, and Acute Haematologic Toxicity of Image-Guided Volumetric Modulated Arc Therapy (IG-VMAT) in the Definitive Treatment of Locally Advanced Carcinoma Cervix. Clinical Medicine Insights: Oncology, 12, 1-10. https://doi.org/10.1177/1179554918783990

Purpose:To evaluate clinical outcomes and failure patterns in patients with locally advanced cervical cancer (LACC) treated definitively using image-guided volumetric-modulated arc therapy (IG-VMAT).Methods and materials:This retrospective review inc... Read More about Early Clinical Outcomes, Patterns of Failure, and Acute Haematologic Toxicity of Image-Guided Volumetric Modulated Arc Therapy (IG-VMAT) in the Definitive Treatment of Locally Advanced Carcinoma Cervix.