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Toby Helliwell's Outputs (83)

Risk of fracture among patients with polymyalgia rheumatica and giant cell arteritis: a population-based study (2018)
Journal Article
Mallen, Roddy, Bucknall, Hider, Muller, Paskins, & Helliwell. (2018). Risk of fracture among patients with polymyalgia rheumatica and giant cell arteritis: a population-based study. BMC Medicine, https://doi.org/10.1186/s12916-017-0987-1

Background
Glucocorticoids are associated with increased fracture risk and are the mainstay of treatment in polymyalgia rheumatica (PMR) and giant cell arteritis (GCA). However, fracture risk in these conditions has not been previously quantified. T... Read More about Risk of fracture among patients with polymyalgia rheumatica and giant cell arteritis: a population-based study.

Possible giant cell arteritis symptoms are common in newly diagnosed patients with Polymyalgia Rheumatica: results from an incident primary care PMR cohort (2017)
Journal Article
Masson, W., Muller, S., Whittle, R., Prior, J., Helliwell, T., Mallen, C., & Hider, S. (2017). Possible giant cell arteritis symptoms are common in newly diagnosed patients with Polymyalgia Rheumatica: results from an incident primary care PMR cohort. BMC Rheumatology, 1, Article 7. https://doi.org/10.1186/s41927-017-0007-2

Background: To examine the frequency of possible giant cell arteritis (GCA) symptoms (including headache, temporal/scalp tenderness, jaw claudication and visual symptoms) in newly diagnosed polymyalgia rheumatica (PMR) patients in UK primary care. Me... Read More about Possible giant cell arteritis symptoms are common in newly diagnosed patients with Polymyalgia Rheumatica: results from an incident primary care PMR cohort.

What is the impact of giant cell arteritis on patients’ lives? A UK qualitative study (2017)
Journal Article
Liddle, J., Bartlam, R., Mallen, C. D., Mackie, S. L., Prior, J. A., Helliwell, T., & Richardson, J. C. (2017). What is the impact of giant cell arteritis on patients’ lives? A UK qualitative study. BMJ Open, 7(8), e017073 -?. https://doi.org/10.1136/bmjopen-2017-017073

OBJECTIVES: Clinical management of giant cell arteritis (GCA) involves balancing the risks and burdens arising from the disease with those arising from treatment, but there is little research on the nature of those burdens. We aimed to explore the im... Read More about What is the impact of giant cell arteritis on patients’ lives? A UK qualitative study.

Diagnostic delay for giant cell arteritis – a systematic review and meta-analysis (2017)
Journal Article
Prior, J. A., Ranjbar, H., Belcher, J., Mackie, S. L., Helliwell, T., Liddle, J., & Mallen, C. D. (2017). Diagnostic delay for giant cell arteritis – a systematic review and meta-analysis. BMC Medicine, 15, Article 120. https://doi.org/10.1186/s12916-017-0871-z

BACKGROUND: Giant cell arteritis (GCA), if untreated, can lead to blindness and stroke. The study's objectives were to (1) determine a new evidence-based benchmark of the extent of diagnostic delay for GCA and (2) examine the role of GCA-specific cha... Read More about Diagnostic delay for giant cell arteritis – a systematic review and meta-analysis.

Association between characteristics of pain and stiffness and the functional status of patients with incident polymyalgia rheumatica from primary care (2017)
Journal Article
Cawley, A., Prior, J., Muller, S., Helliwell, T., Hider, S., Dasgupta, B., …Mallen, C. (2017). Association between characteristics of pain and stiffness and the functional status of patients with incident polymyalgia rheumatica from primary care. Clinical Rheumatology, 37(6), 1639-1644. https://doi.org/10.1007/s10067-017-3730-6

This paper aims to examine the relationship between different characteristics of pain and stiffness and the functional status of patients with newly diagnosed polymyalgia rheumatica (PMR). Baseline analysis of an inception cohort study was conducted.... Read More about Association between characteristics of pain and stiffness and the functional status of patients with incident polymyalgia rheumatica from primary care.

SAT0672 Risk of fragility fracture among patients with psoriasis: a population based matched cohort study from the united kingdom (2017)
Presentation / Conference
Paskins, Z., Whittle, R., Sultan, A. A., Muller, S., Helliwell, T., Blagojevic-Bucknall, M., …Mallen, C. (2017, June). SAT0672 Risk of fragility fracture among patients with psoriasis: a population based matched cohort study from the united kingdom. Poster presented at Annual European Congress of Rheumatology, 14–17 June, 2017

SAT0708 Symptoms indicative of inflammatory arthritis are common in the primary care population: findings from the symptoms in persons at risk of rheumatoid arthritis survey (2017)
Presentation / Conference
Hider, S., Muller, S., Prior, J., Helliwell, T., Schaardenburg, D. V., Mil, A. V. D. H., …Mallen, C. (2017, June). SAT0708 Symptoms indicative of inflammatory arthritis are common in the primary care population: findings from the symptoms in persons at risk of rheumatoid arthritis survey. Paper presented at Annual European Congress of Rheumatology, 14–17 June, 2017

Characterising those with incident polymyalgia rheumatica in primary care: results from the PMR Cohort Study. (2016)
Journal Article
Muller, S., Hider, S. L., Helliwell, T., Lawton, S., Barraclough, K., Dasgupta, B., …Mallen, C. D. (2016). Characterising those with incident polymyalgia rheumatica in primary care: results from the PMR Cohort Study. Arthritis Research and Therapy, https://doi.org/10.1186/s13075-016-1097-8

BACKGROUND: The aim was to characterise the sociodemographic, general health and polymyalgia rheumatica (PMR)-specific features of participants in a large inception cohort of patients with PMR diagnosed in UK primary care. METHODS: Patients (n?=?739)... Read More about Characterising those with incident polymyalgia rheumatica in primary care: results from the PMR Cohort Study..

Development of a Provisional Core Domain Set for Polymyalgia Rheumatica: Report from the OMERACT 12 Polymyalgia Rheumatica Working Group. (2016)
Journal Article
Mallen, & Helliwell. (2016). Development of a Provisional Core Domain Set for Polymyalgia Rheumatica: Report from the OMERACT 12 Polymyalgia Rheumatica Working Group. Journal of Rheumatology, 182 - 186. https://doi.org/10.3899/jrheum.141179

OBJECTIVE: The Outcome Measures in Rheumatology (OMERACT) polymyalgia rheumatica (PMR) working group aims to develop a core set of outcome measures to be used in clinical trials for PMR. Previous reports from OMERACT 11 included a qualitative study o... Read More about Development of a Provisional Core Domain Set for Polymyalgia Rheumatica: Report from the OMERACT 12 Polymyalgia Rheumatica Working Group..

306. How Do General Practitioners Manage Suspected Giant Cell Arteritis (2015)
Journal Article
Helliwell, T., Muller, S., Hider, S. L., Richardson, J., & Mallen, C. (2015). 306. How Do General Practitioners Manage Suspected Giant Cell Arteritis. Rheumatology, 54(S1), https://doi.org/10.1093/rheumatology/kev090.071

Background: Background: GCA is the commonest large vessel vasculitis yet a full time UK general practitioner (GP) can expect to see just one case, at most every 1–2 years. Untreated GCA can lead to permanent visual loss, thus it is essential GPs reco... Read More about 306. How Do General Practitioners Manage Suspected Giant Cell Arteritis.

Risk of vascular events in patients with polymyalgia rheumatica. (2014)
Journal Article
Hancock, A. T., Mallen, C. D., Muller, S., Belcher, J., Roddy, E., Helliwell, T., & Hider, S. L. (2014). Risk of vascular events in patients with polymyalgia rheumatica. Canadian Medical Association Journal, 186(13), E495 - E501. https://doi.org/10.1503/cmaj.140266

BACKGROUND: Polymyalgia rheumatica is one of the most common inflammatory rheumatologic conditions in older adults. Other inflammatory rheumatologic disorders are associated with an excess risk of vascular disease. We investigated whether polymyalgia... Read More about Risk of vascular events in patients with polymyalgia rheumatica..

Is cancer associated with polymyalgia rheumatica?: A cohort study in the General Practice Research Database (2014)
Journal Article
Muller, S., Hider, S. L., Belcher, J., Helliwell, T., & Mallen, C. D. (2014). Is cancer associated with polymyalgia rheumatica?: A cohort study in the General Practice Research Database. Annals of the Rheumatic Diseases, 73(10), 1769 -1773. https://doi.org/10.1136/annrheumdis-2013-203465

OBJECTIVE: To investigate the incidence of new cancer diagnoses in a community sample of patients with polymyalgia rheumatica (PMR). METHODS: All incident cases of PMR in the UK General Practice Research Database (GPRD) (1987-99), without pre-existin... Read More about Is cancer associated with polymyalgia rheumatica?: A cohort study in the General Practice Research Database.

HOW DO GENERAL PRACTITIONERS IDENTIFY GIANT CELL ARTERITIS (GCA)? (2014)
Journal Article
Helliwell, T., Muller, S., Hider, S. L., Richardson, J., & Mallen, C. (2014). HOW DO GENERAL PRACTITIONERS IDENTIFY GIANT CELL ARTERITIS (GCA)?. Annals of the Rheumatic Diseases, 73(S2), 1004-1004. https://doi.org/10.1136/annrheumdis-2014-eular.4634

Background Giant Cell Arteritis (GCA) is the commonest large vessel vasculitis yet a full time UK general practitioner (GP) can expect to see just 1 case every 1-2 years [Barraclough]. GCA may be difficult to identify, particularly in atypical cases.... Read More about HOW DO GENERAL PRACTITIONERS IDENTIFY GIANT CELL ARTERITIS (GCA)?.

OP0298-PC How General Practitioners Diagnose Polymyalgia Rheumatica (2013)
Journal Article
Helliwell, T., Muller, S., Hider, S. L., & Mallen, C. D. (2013). OP0298-PC How General Practitioners Diagnose Polymyalgia Rheumatica. Annals of the Rheumatic Diseases, 72(Suppl 3), A155.1-A155. https://doi.org/10.1136/annrheumdis-2013-eular.503

Background The initial diagnosis of polymyalgia rheumatica (PMR) is often made in primary care. Given the non-specific nature of PMR symptoms, diagnosis can be challenging especially as many disorders can mimic the symptoms of PMR. Although guideline... Read More about OP0298-PC How General Practitioners Diagnose Polymyalgia Rheumatica.