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Divya Chari's Outputs (6)

In vitro model of neurotrauma using the chick embryo to test regenerative bioimplantation. (2023)
Journal Article
Mogas Barcons, A., Chari, D. M., & Adams, C. (in press). In vitro model of neurotrauma using the chick embryo to test regenerative bioimplantation. Alternatives to animal experimentation : a journal for new paths in biomedical science / edited by the Swiss Society ALTEX Edition, 41(2), 202-212. https://doi.org/10.14573/altex.2304171

Effective repair of spinal cord injury sites remains a major clinical challenge. One promising strategy is the implantation of multifunctional bioscaffolds to enhance nerve fibre growth, guide regenerating tissue and modulate scarring/inflammation pr... Read More about In vitro model of neurotrauma using the chick embryo to test regenerative bioimplantation..

Systematic Alignment Analysis of Neural Transplant Cells in Electrospun Nanofibre Scaffolds (2022)
Journal Article
Mogas Barcons, A., Chowdhury, F., Chari, D. M., & Adams, C. (2022). Systematic Alignment Analysis of Neural Transplant Cells in Electrospun Nanofibre Scaffolds. Materials, 16(1), Article 124. https://doi.org/10.3390/ma16010124

Spinal cord injury is debilitating with functional loss often permanent due to a lack of neuro-regenerative or neuro-therapeutic strategies. A promising approach to enhance biological function is through implantation of tissue engineered constructs,... Read More about Systematic Alignment Analysis of Neural Transplant Cells in Electrospun Nanofibre Scaffolds.

Enhancing the regenerative potential of stem cell-laden, clinical-grade implants through laminin engineering (2021)
Journal Article
Mogas Barcons, A., Chari, D., & Adams, C. (2021). Enhancing the regenerative potential of stem cell-laden, clinical-grade implants through laminin engineering. Materials Science and Engineering: C, 123, https://doi.org/10.1016/j.msec.2021.111931

Protected delivery of neural stem cells (NSCs; a major transplant population) within bioscaffolds has the potential to improve regenerative outcomes in sites of spinal cord injury. Emergent research has indicated clinical grade bioscaffolds (e.g. tho... Read More about Enhancing the regenerative potential of stem cell-laden, clinical-grade implants through laminin engineering.

Electrophysiological properties of neurons grown on soft polymer scaffolds reveal the potential to develop neuromimetic culture environments (2020)
Journal Article
Evans, M. G., Al-Shakli, A., & Chari, D. M. (2020). Electrophysiological properties of neurons grown on soft polymer scaffolds reveal the potential to develop neuromimetic culture environments. Integrative Biology, 395-403. https://doi.org/10.1093/intbio/zyz033

Tissue engineering methodologies for various physiological systems are seeing a significant trend towards 3-D cell culture in or on ‘soft’ polymeric hydrogel materials, widely considered to provide a more biomimetic environment for cell growth versus... Read More about Electrophysiological properties of neurons grown on soft polymer scaffolds reveal the potential to develop neuromimetic culture environments.

Development and characterisation of neurocompatible transfection grade magnetic nanoparticles for genetic modification of neural stem cells (2016)
Journal Article
Chari, & Adams. (2016). Development and characterisation of neurocompatible transfection grade magnetic nanoparticles for genetic modification of neural stem cells. Advanced healthcare materials, 841-849. https://doi.org/10.1002/adhm.201500885

Genetic modification of cell transplant populations and cell tracking ability are key underpinnings for effective cell therapies. Current strategies to achieve these goals utilize methods which are unsuitable for clinical translation because of relat... Read More about Development and characterisation of neurocompatible transfection grade magnetic nanoparticles for genetic modification of neural stem cells.