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Christian Mallen's Outputs (555)

Variation in GP decisions on antihypertensive treatment in oldest-old and frail individuals across 29 countries (2017)
Journal Article
Mallen. (2017). Variation in GP decisions on antihypertensive treatment in oldest-old and frail individuals across 29 countries. BMC Geriatrics, 93 -?. https://doi.org/10.1186/s12877-017-0486-4

BACKGROUND: In oldest-old patients (>80), few trials showed efficacy of treating hypertension and they included mostly the healthiest elderly. The resulting lack of knowledge has led to inconsistent guidelines, mainly based on systolic blood pressure... Read More about Variation in GP decisions on antihypertensive treatment in oldest-old and frail individuals across 29 countries.

The effects of implementing a point-of-care electronic template to prompt routine anxiety and depression screening in patients consulting for osteoarthritis (the Primary Care Osteoarthritis Trial): A cluster randomised trial in primary care (2017)
Journal Article
Mallen, C. D., Nicholl, B. I., Lewis, M., Bartlam, B., Green, D., Jowett, S., …Peat, G. (2017). The effects of implementing a point-of-care electronic template to prompt routine anxiety and depression screening in patients consulting for osteoarthritis (the Primary Care Osteoarthritis Trial): A cluster randomised trial in primary care. PLoS Medicine, e1002273 -?. https://doi.org/10.1371/journal.pmed.1002273

BACKGROUND: This study aimed to evaluate whether prompting general practitioners (GPs) to routinely assess and manage anxiety and depression in patients consulting with osteoarthritis (OA) improves pain outcomes. METHODS AND FINDINGS: We conducted a... Read More about The effects of implementing a point-of-care electronic template to prompt routine anxiety and depression screening in patients consulting for osteoarthritis (the Primary Care Osteoarthritis Trial): A cluster randomised trial in primary care.

Incident acute pseudogout and prior bisphosphonate use: matched case-control study in the UK-Clinical Practice Research Datalink (2017)
Journal Article
Roddy, E., Muller, S., Paskins, Z., Hider, S., Blagojevic-Bucknall, M., & Mallen, C. (2017). Incident acute pseudogout and prior bisphosphonate use: matched case-control study in the UK-Clinical Practice Research Datalink. Medicine, https://doi.org/10.1097/MD.0000000000006177

Oral bisphosphonates are the most commonly used drugs to treat postmenopausal osteoporosis. Acute pseudogout is anecdotally reported to occur following bisphosphonate initiation but empirical data are lacking. We investigated whether treatment with o... Read More about Incident acute pseudogout and prior bisphosphonate use: matched case-control study in the UK-Clinical Practice Research Datalink.

Prognosis research ideally should measure time-varying predictors at their intended moment of use (2017)
Journal Article
Whittle, R., Royle, K., Jordan, K. P., Riley, R. D., Mallen, C. D., & Peat, G. (2017). Prognosis research ideally should measure time-varying predictors at their intended moment of use. Diagnostic and Prognostic Research, 1, Article 1. https://doi.org/10.1186/s41512-016-0006-6

Background
Prognosis research studies (e.g. those deriving prognostic models or examining potential predictors of outcome) often collect information on time-varying predictors after their intended moment of use, sometimes using a measurement method... Read More about Prognosis research ideally should measure time-varying predictors at their intended moment of use.

Patients' views on the causes of their polymyalgia rheumatica: a content analysis of data from the PMR Cohort Study (2017)
Journal Article
Tshimologo, M., Saunders, B., Muller, S., Mallen, C. D., & Hider, S. L. (2017). Patients' views on the causes of their polymyalgia rheumatica: a content analysis of data from the PMR Cohort Study. BMJ Open, e014301 -?. https://doi.org/10.1136/bmjopen-2016-014301

OBJECTIVE: To explore primary care polymyalgia rheumatica (PMR) patient beliefs about the causes of their PMR. DESIGN: Qualitative content analysis was conducted on patients' written responses to the question of what they thought had caused their PMR... Read More about Patients' views on the causes of their polymyalgia rheumatica: a content analysis of data from the PMR Cohort Study.

Generic prognostic factors for musculoskeletal pain in primary care: a systematic review. (2017)
Journal Article
Artus, M., Campbell, P., Mallen, C., Dunn, K., & van der Windt, D. (2017). Generic prognostic factors for musculoskeletal pain in primary care: a systematic review. BMJ Open, e012901 - ?. https://doi.org/10.1136/bmjopen-2016-012901

OBJECTIVES: To summarise the evidence for generic prognostic factors across a range of musculoskeletal (MSK) conditions. SETTING: primary care. METHODS AND OUTCOMES: Comprehensive systematic literature review. MEDLINE, CINAHL, PsychINFO and EMBASE we... Read More about Generic prognostic factors for musculoskeletal pain in primary care: a systematic review..

Rheumatoid arthritis is getting less frequent: results of a nationwide population based cohort study (2017)
Journal Article
Mallen, C. (2017). Rheumatoid arthritis is getting less frequent: results of a nationwide population based cohort study. Rheumatology, 736-744. https://doi.org/10.1093/rheumatology/kew468

Abstract Objectives: The objectives of this study were to examine changes in incidence and prevalence of RA between 1990 and 2014, and to explore if there is any geographic variation in incidence and prevalence of RA in the UK Methods: Design Prospec... Read More about Rheumatoid arthritis is getting less frequent: results of a nationwide population based cohort study.

Predicting Mortality from Change-over-time in the Charlson Comorbidity Index: A retrospective cohort study in a data-intensive UK health system (2016)
Journal Article
Mamas, M., & Mallen, C. (2016). Predicting Mortality from Change-over-time in the Charlson Comorbidity Index: A retrospective cohort study in a data-intensive UK health system. Medicine, e4973. https://doi.org/10.1097/md.0000000000004973

Multimorbidity is common among older people and presents a major challenge to health systems worldwide. Metrics of multimorbidity are, however, crude: focusing on measuring comorbid conditions at single time-points rather than reflecting the longitud... Read More about Predicting Mortality from Change-over-time in the Charlson Comorbidity Index: A retrospective cohort study in a data-intensive UK health system.

Keele Aches and Pains Study protocol: validity, acceptability, and feasibility of the Keele STarT MSK tool for subgrouping musculoskeletal patients in primary care. (2016)
Journal Article
Campbell, P., Hill, J., Protheroe, J., Afolabi, E., Lewis, M., Beardmore, R., …Dunn, K. (2016). Keele Aches and Pains Study protocol: validity, acceptability, and feasibility of the Keele STarT MSK tool for subgrouping musculoskeletal patients in primary care. Journal of Pain Research, 2016(9), 807 -818. https://doi.org/10.2147/JPR.S116614

Musculoskeletal conditions represent a considerable burden worldwide, and are predominantly managed in primary care. Evidence suggests that many musculoskeletal conditions share similar prognostic factors. Systematically assessing patient’s prognosis... Read More about Keele Aches and Pains Study protocol: validity, acceptability, and feasibility of the Keele STarT MSK tool for subgrouping musculoskeletal patients in primary care..

Illness perceptions of gout patients and the use of allopurinol in primary care: baseline findings from a prospective cohort study (2016)
Journal Article
Walsh, C. P., Prior, J., Chandratre, P., Belcher, J., Mallen, C., & Roddy, E. (2016). Illness perceptions of gout patients and the use of allopurinol in primary care: baseline findings from a prospective cohort study. BMC Musculoskeletal Disorders, 17, Article 394. https://doi.org/10.1186/s12891-016-1252-z

Background
Patients’ perceptions of their illness are dynamic and can directly influence aspects of management. Our aim was to examine the illness perceptions of gout patients in UK primary care and associations with allopurinol use.

Methods
A h... Read More about Illness perceptions of gout patients and the use of allopurinol in primary care: baseline findings from a prospective cohort study.

Characterising those with incident polymyalgia rheumatica in primary care: results from the PMR Cohort Study. (2016)
Journal Article
Muller, S., Hider, S. L., Helliwell, T., Lawton, S., Barraclough, K., Dasgupta, B., …Mallen, C. D. (2016). Characterising those with incident polymyalgia rheumatica in primary care: results from the PMR Cohort Study. Arthritis Research and Therapy, https://doi.org/10.1186/s13075-016-1097-8

BACKGROUND: The aim was to characterise the sociodemographic, general health and polymyalgia rheumatica (PMR)-specific features of participants in a large inception cohort of patients with PMR diagnosed in UK primary care. METHODS: Patients (n?=?739)... Read More about Characterising those with incident polymyalgia rheumatica in primary care: results from the PMR Cohort Study..

Prevalence of cardiovascular-related comorbidity in ankylosing spondylitis, psoriatic arthritis and psoriasis in primary care: a matched retrospective cohort study. (2016)
Report
Ahmed, N., Prior, J., Chen, Y., Hayward, R., Mallen, C., & Hider, S. (2016). Prevalence of cardiovascular-related comorbidity in ankylosing spondylitis, psoriatic arthritis and psoriasis in primary care: a matched retrospective cohort study

The aim of this study is to compare the prevalence of cardiovascular (CVD)-related comorbidities in patients with ankylosing spondylitis (AS), psoriatic arthritis (PsA) or psoriasis (Ps) in UK primary care against matched cohorts. Matched retrospecti... Read More about Prevalence of cardiovascular-related comorbidity in ankylosing spondylitis, psoriatic arthritis and psoriasis in primary care: a matched retrospective cohort study..

2016 updated EULAR evidence-based recommendations for the management of gout. (2016)
Journal Article
Richette, P., Doherty, M., Pascual, E., Barskova, V., Becce, F., Castañeda-Sanabria, J., …Bardin, T. (2016). 2016 updated EULAR evidence-based recommendations for the management of gout. Annals of the Rheumatic Diseases, 76(1), 29 - 42. https://doi.org/10.1136/annrheumdis-2016-209707

BACKGROUND: New drugs and new evidence concerning the use of established treatments have become available since the publication of the first European League Against Rheumatism (EULAR) recommendations for the management of gout, in 2006. This situatio... Read More about 2016 updated EULAR evidence-based recommendations for the management of gout..

Symptom recognition and perceived urgency of help-seeking for rheumatoid arthritis and other diseases in the general public: A mixed method approach. (2016)
Journal Article
Simons, G., Belcher, J., Morton, C., Kumar, K., Falahee, M., Mallen, C. D., …Raza, K. (2017). Symptom recognition and perceived urgency of help-seeking for rheumatoid arthritis and other diseases in the general public: A mixed method approach. Arthritis Care and Research, 69(5), 633-641. https://doi.org/10.1002/acr.22979

OBJECTIVE: Clinical outcomes in rheumatoid arthritis (RA) are improved if the disease is treated early. However, treatment is often significantly delayed as a result of delayed help-seeking by patients who fail to recognise its symptoms or the need f... Read More about Symptom recognition and perceived urgency of help-seeking for rheumatoid arthritis and other diseases in the general public: A mixed method approach..

DIAGNOSTIC DELAY FOR GIANT CELL ARTERITIS (GCA). A SYSTEMATIC REVIEW AND META-ANALYSIS (2016)
Journal Article
Prior, J. A., Ranjbar, H., Belcher, J., Mackie, S., & Mallen, C. D. (2016). DIAGNOSTIC DELAY FOR GIANT CELL ARTERITIS (GCA). A SYSTEMATIC REVIEW AND META-ANALYSIS. Annals of the Rheumatic Diseases, 75(S2), 1092-1092. https://doi.org/10.1136/annrheumdis-2016-eular.2639

Background The diagnosis of giant cell arteritis (GCA) remains difficult, with patients often presenting with non-specific and atypical symptoms. Such ambiguity can lead to delays in the diagnosis of GCA, which in-turn may result in the patient exper... Read More about DIAGNOSTIC DELAY FOR GIANT CELL ARTERITIS (GCA). A SYSTEMATIC REVIEW AND META-ANALYSIS.

PATIENT PRIORITIES FOR PMR RESEARCH: A PRIMARY CARE SURVEY (2016)
Journal Article
Hider, S., Morton, C., Muller, S., Belcher, J., Gilbert, K., Bucknall, M., & Mallen, C. (2016). PATIENT PRIORITIES FOR PMR RESEARCH: A PRIMARY CARE SURVEY. Annals of the Rheumatic Diseases, 75, 169-169. https://doi.org/10.1136/annrheumdis-2016-eular.5915

Background Polymyalgia rheumatica (PMR) is a common inflammatory disorder of older (>50 years) adults, frequently managed in primary care. PMR remains under-researched despite the significant impact this condition has on patient's quality of life. Ex... Read More about PATIENT PRIORITIES FOR PMR RESEARCH: A PRIMARY CARE SURVEY.