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Christian Mallen's Outputs (555)

Systematic Review of the Association of the Hospital Frailty Risk Score with Mortality in Patients with Cerebrovascular and Cardiovascular Disease. (2024)
Journal Article
Sokhal, B. S., Menon, S. P. K., Willes, C., Corp, N., Matetić, A., Mallen, C., & Mamas, M. (in press). Systematic Review of the Association of the Hospital Frailty Risk Score with Mortality in Patients with Cerebrovascular and Cardiovascular Disease. Current Cardiology Reviews, 20(3), Article e290224227533. https://doi.org/10.2174/011573403X276647240217112151

There is limited systematic data on the association between the Hospital Frailty Risk Score (HFRS) and characteristics and mortality in patients with cerebrovascular and cardiovascular disease (CVD). This systematic review aimed to summarise the use... Read More about Systematic Review of the Association of the Hospital Frailty Risk Score with Mortality in Patients with Cerebrovascular and Cardiovascular Disease..

Evaluating the impact of the supporting the advancement of research skills (STARS) programme on research knowledge, engagement and capacity-building in a health and social care organisation in England (2024)
Journal Article
Tajuria, G., Dobel-Ober, D., Bradley, E., Charnley, C., Lambley-Burke, R., Mallen, C., …Kingstone, T. (in press). Evaluating the impact of the supporting the advancement of research skills (STARS) programme on research knowledge, engagement and capacity-building in a health and social care organisation in England. BMC Medical Education, 24(1), Article 126. https://doi.org/10.1186/s12909-024-05059-0

Objectives
To evaluate the impact a novel education programme - to improve research engagement, awareness, understanding and confidence - had on a diverse health and social care workforce. Barriers and facilitators to engagement were explored togeth... Read More about Evaluating the impact of the supporting the advancement of research skills (STARS) programme on research knowledge, engagement and capacity-building in a health and social care organisation in England.

Betwixt and between student and professional identities: UK medical students during COVID times (2024)
Journal Article
Polidano, K., Wenning, B., Mallen, C. D., & Dikomitis, L. (2024). Betwixt and between student and professional identities: UK medical students during COVID times. SN Social Sciences, 4(2), Article 53. https://doi.org/10.1007/s43545-024-00844-6

The COVID-19 pandemic lockdown in Spring 2020 brought about unprecedented disruption to medical education in the United Kingdom (UK). Medical students were encouraged to take up paid roles in the National Health Service to help with workforce shortag... Read More about Betwixt and between student and professional identities: UK medical students during COVID times.

Optimising the implementation of evidence-based osteoarthritis guidelines in primary care: Development of a Knowledge Mobilisation Toolkit (2024)
Journal Article
Swaithes, L., Paskins, Z., Finney, A., Walsh, N., Skrybant, M., Mallen, C., & Dziedzic, K. (2024). Optimising the implementation of evidence-based osteoarthritis guidelines in primary care: Development of a Knowledge Mobilisation Toolkit. Osteoarthritis and Cartilage, https://doi.org/10.1016/j.joca.2024.01.003

Objective
Implementing clinical guidelines for osteoarthritis in primary care is complex. Whilst international guidelines detail what best practice for osteoarthritis looks like, little is known about how this is... Read More about Optimising the implementation of evidence-based osteoarthritis guidelines in primary care: Development of a Knowledge Mobilisation Toolkit.

Co-development and testing of an extended community pharmacy model of service delivery for managing osteoarthritis: protocol for a sequential, multi-methods study (PharmOA) (2024)
Journal Article
Babatunde, O. O., Cottrell, E., White, S., Chudyk, A., Healey, E. L., Edwards, J., …Holden, M. A. (2024). Co-development and testing of an extended community pharmacy model of service delivery for managing osteoarthritis: protocol for a sequential, multi-methods study (PharmOA). BMC Musculoskeletal Disorders, 25(1), Article 54. https://doi.org/10.1186/s12891-023-07105-2

Background
Osteoarthritis is a common, painful and disabling long-term condition. Delivery of high-quality guideline-informed osteoarthritis care that successfully promotes and maintains supported self-management is imperative. However, osteoarthrit... Read More about Co-development and testing of an extended community pharmacy model of service delivery for managing osteoarthritis: protocol for a sequential, multi-methods study (PharmOA).

EULAR recommendations for the non-pharmacological core management of hip and knee osteoarthritis: 2023 update. (2024)
Journal Article
Moseng, T., Vliet Vlieland, T. P. M., Battista, S., Beckwée, D., Boyadzhieva, V., Conaghan, P. G., …Østerås, N. (in press). EULAR recommendations for the non-pharmacological core management of hip and knee osteoarthritis: 2023 update. Annals of the Rheumatic Diseases, https://doi.org/10.1136/ard-2023-225041

Hip and knee osteoarthritis (OA) are increasingly common with a significant impact on individuals and society. Non-pharmacological treatments are considered essential to reduce pain and improve function and quality of life. EULAR recommendations for... Read More about EULAR recommendations for the non-pharmacological core management of hip and knee osteoarthritis: 2023 update..

Undertaking multi-centre randomised controlled trials in primary care: learnings and recommendations from the PULsE-AI trial researchers (2024)
Journal Article
Pollock, K. G., Dickerson, C., Kainth, M., Lawton, S., Hurst, M., Sugrue, D. M., …Cohen, A. T. (in press). Undertaking multi-centre randomised controlled trials in primary care: learnings and recommendations from the PULsE-AI trial researchers. BMC Primary Care, 25(1), Article 7. https://doi.org/10.1186/s12875-023-02246-8

Background
Conducting effective and translational research can be challenging and few trials undertake formal reflection exercises and disseminate learnings from them. Following completion of our multicentre randomised controlled trial, which was im... Read More about Undertaking multi-centre randomised controlled trials in primary care: learnings and recommendations from the PULsE-AI trial researchers.

A person-centred consultation intervention to improve shared decision-making about, and uptake of, osteoporosis medicines (iFraP): a pragmatic, parallel-group, individual randomised controlled trial protocol. (2024)
Journal Article
Bullock, L., Nicholls, E., Cherrington, A., Butler-Walley, S., Clark, E. M., Fleming, J., …Paskins, Z. (2024). A person-centred consultation intervention to improve shared decision-making about, and uptake of, osteoporosis medicines (iFraP): a pragmatic, parallel-group, individual randomised controlled trial protocol. NIHR Open Research, 4(14), 14. https://doi.org/10.3310/nihropenres.13571.1

BackgroundGood quality shared decision-making (SDM) conversations involve people with, or at risk of osteoporosis and clinicians collaborating to decide, where appropriate, which evidence-based medicines best fit the person's life, beliefs, and value... Read More about A person-centred consultation intervention to improve shared decision-making about, and uptake of, osteoporosis medicines (iFraP): a pragmatic, parallel-group, individual randomised controlled trial protocol..

785 Co-contextualising and Implementing evidence-based care model for osteoarthritis: Nigerian case study in the Joint Implementation of Guidelines for OSteoArthritis in West-Africa (JIGSAW-A) (2024)
Presentation / Conference
Babatunde, O. O., Adetunji, O. A., Alonge, I., Owoyemi, T., Taiwo, P., Ogunbanjo, A., …Mallen, C. (2024, January). 785 Co-contextualising and Implementing evidence-based care model for osteoarthritis: Nigerian case study in the Joint Implementation of Guidelines for OSteoArthritis in West-Africa (JIGSAW-A). Poster presented at 2024 OARSI World Congress on Osteoarthritis, Vienna, Austira

Impact of the COVID-19 pandemic on young people living with HIV in Lesotho: a qualitative study (2024)
Journal Article
Shepherd, T., Robinson, M. E., Ramaema, M., Rakuoane, M., Moletsane, N., Mpholo, R., …Leigh, G. (2024). Impact of the COVID-19 pandemic on young people living with HIV in Lesotho: a qualitative study. BMJ Public Health, 2(1), Article e000414. https://doi.org/10.1136/bmjph-2023-000414

Introduction: There is a growing body of research evidencing the detrimental impact of the COVID-19 pandemic on the mental health and well-being of young people. This impact may be worse in low-resource settings, especially those in sub-Saharan Afric... Read More about Impact of the COVID-19 pandemic on young people living with HIV in Lesotho: a qualitative study.

Variation in UK fracture liaison service consultation conduct and content before and during the COVID pandemic: results from the iFraP-D UK survey (2023)
Journal Article
Bullock, L., Abdelmagid, S., Fleming, J., Leyland, S., Clark, E. M., Gidlow, C., …Paskins, Z. (2023). Variation in UK fracture liaison service consultation conduct and content before and during the COVID pandemic: results from the iFraP-D UK survey. Archives of Osteoporosis, 19(1), Article 5. https://doi.org/10.1007/s11657-023-01361-4

Summary
We conducted a survey of FLSs’ consultation conduct and content which identified marked variation in whether FLS HCPs discussed osteoporosis medicine with patients. A review of service pro formas showed more content related to ‘investigating... Read More about Variation in UK fracture liaison service consultation conduct and content before and during the COVID pandemic: results from the iFraP-D UK survey.

Acceptability of a proposed practice pharmacist-led review for opioid-treated patients with persistent pain: A qualitative study to inform intervention development (2023)
Journal Article
Cornwall, N., Woodcock, C., Ashworth, J., Harrisson, S. A., Dikomitis, L., White, S., …on behalf of the PROMPPT team. (2023). Acceptability of a proposed practice pharmacist-led review for opioid-treated patients with persistent pain: A qualitative study to inform intervention development. British Journal of Pain, https://doi.org/10.1177/20494637231221688

Introduction
Regular review of patients prescribed opioids for persistent non-cancer pain (PCNP) is recommended but not routinely undertaken. The PROMPPT (Proactive clinical Review of patients taking Opioid Medicines long-term for persistent Pain le... Read More about Acceptability of a proposed practice pharmacist-led review for opioid-treated patients with persistent pain: A qualitative study to inform intervention development.

The cost-effectiveness of adding an ultrasound corticosteroid and local anaesthetic injection to advice and education for hip osteoarthritis (2023)
Journal Article
Kigozi, J., Oppong, R., Paskins, Z., Bromley, K., Lewis, M., Hughes, G., …Roddy, E. (2023). The cost-effectiveness of adding an ultrasound corticosteroid and local anaesthetic injection to advice and education for hip osteoarthritis. Rheumatology, https://doi.org/10.1093/rheumatology/kead659

Objectives. Evidence for the comparative cost-effectiveness of intra-articular corticosteroid injection in people with hip osteoarthritis (OA) remains unclear. This study investigated the cost-effectiveness of best current treatment (BCT) comprising... Read More about The cost-effectiveness of adding an ultrasound corticosteroid and local anaesthetic injection to advice and education for hip osteoarthritis.

Management and treatment of children, young people and adults with systemic lupus erythematosus: British Society for Rheumatology guideline scope (2023)
Journal Article
Md Yusof, M. Y., Smith, E. M. D., Ainsworth, S., Armon, K., Beresford, M. W., Brown, M., …Vital, E. M. (in press). Management and treatment of children, young people and adults with systemic lupus erythematosus: British Society for Rheumatology guideline scope. Rheumatology Advances in Practice, 7(3), rkad093. https://doi.org/10.1093/rap/rkad093

Lay Summary: Systemic lupus erythematosus (SLE) is a lifelong condition in which the immune system damages the body’s own tissues, causing various symptoms including rashes, hair loss, mouth ulcers, joint pain and overwhelming tiredness. It can also... Read More about Management and treatment of children, young people and adults with systemic lupus erythematosus: British Society for Rheumatology guideline scope.

Improving the understanding and management of back pain in older adults: the BOOST research programme including RCT and OPAL cohort (2023)
Report
Williamson, E., Sanchez-Santos, M. T., Marian, I. R., Maredza, M., Srikesavan, C., Garrett, A., …Lamb, S. E. (2023). Improving the understanding and management of back pain in older adults: the BOOST research programme including RCT and OPAL cohort. NIHR

Background Back pain frequently affects older people. Knowledge about back pain in older people and evidence to inform clinical care was lacking, particularly for older people with neurogenic claudication due to spinal stenosis, which is a debilitati... Read More about Improving the understanding and management of back pain in older adults: the BOOST research programme including RCT and OPAL cohort.

Pre-existing musculoskeletal pain and its association with mortality in newly diagnosed co-morbid conditions: an electronic health record cohort study (2023)
Journal Article
Marshall, M., Mason, K. J., Edwards, J. J., Mamas, M. A., Bailey, J., Heron, N., …Jordan, K. P. (2023). Pre-existing musculoskeletal pain and its association with mortality in newly diagnosed co-morbid conditions: an electronic health record cohort study. Rheumatology Advances in Practice, 8(1), Article rkad104. https://doi.org/10.1093/rap/rkad104

Objective
Musculoskeletal pain is a common risk factor for co-morbid conditions and might increase the risk of poor outcomes. The objective was to determine whether patients with pre-existing musculoskeletal pain have an increased risk for mortality... Read More about Pre-existing musculoskeletal pain and its association with mortality in newly diagnosed co-morbid conditions: an electronic health record cohort study.

Musculoskeletal disorders and pain in agricultural workers in Low- and Middle-Income Countries: a systematic review and meta-analysis (2023)
Journal Article
Shivakumar, M., Welsh, V., Bajpai, R., Helliwell, T., Mallen, C., Robinson, M., & Shepherd, T. (2024). Musculoskeletal disorders and pain in agricultural workers in Low- and Middle-Income Countries: a systematic review and meta-analysis. Rheumatology International, 44, 235–247. https://doi.org/10.1007/s00296-023-05500-5

Agricultural workers constitute two-thirds of the population of Low- and Middle-Income Countries (LMIC) and are at increased risk of developing musculoskeletal disorders (MSD) due to high-risk activities. This systematic review and meta-analysis aim... Read More about Musculoskeletal disorders and pain in agricultural workers in Low- and Middle-Income Countries: a systematic review and meta-analysis.

Cohort study investigating gout flares and management in UK general practice (2023)
Journal Article
Finnikin, S., Mallen, C. D., & Roddy, E. (in press). Cohort study investigating gout flares and management in UK general practice. BMC Primary Care, 24(1), 246. https://doi.org/10.1186/s12875-023-02201-7

Background: Gout is the most common inflammatory arthritis and is almost exclusively managed in primary care, however the course and severity of the condition is variable and poorly characterised. This research aims improve understanding about the fr... Read More about Cohort study investigating gout flares and management in UK general practice.

Trends in Cardiovascular Mortality Among Individuals with Alzheimer's Disease in the United States, 1999-2020 (2023)
Journal Article
Ranganathan, S., Abramov, D., Chew, N. W., Mallen, C., Marshall, M., Kobo, O., & Mamas, M. A. (2024). Trends in Cardiovascular Mortality Among Individuals with Alzheimer's Disease in the United States, 1999-2020. The American Journal of Cardiology, 211, Article 326-333. https://doi.org/10.1016/j.amjcard.2023.11.044

This study aimed to compare the trends in cardiovascular diseases (CVD)-related mortality in patients with Alzheimer's Disease (AD) and in the general population aged 65 and above. Data from the CDC WONDER Multiple Cause of Death da... Read More about Trends in Cardiovascular Mortality Among Individuals with Alzheimer's Disease in the United States, 1999-2020.