Asymmetric synthesis of primary amines catalyzed by thermotolerant fungal reductive aminases (2020)
Journal Article
Mangas-Sanchez, J., Sharma, M., Cosgrove, S. C., Ramsden, J. I., Marshall, J. R., Thorpe, T. W., …Turner, N. J. (in press). Asymmetric synthesis of primary amines catalyzed by thermotolerant fungal reductive aminases. Chemical Science, 11(19), 5052-5057. https://doi.org/10.1039/d0sc02253e

Chiral primary amines are important intermediates in the synthesis of pharmaceutical compounds. Fungal reductive aminases (RedAms) are NADPH-dependent dehydrogenases that catalyse reductive amination of a range of ketones with short-chain primary ami... Read More about Asymmetric synthesis of primary amines catalyzed by thermotolerant fungal reductive aminases.

Microbial interactions in the mosquito gut determine Serratia colonization and blood-feeding propensity (2020)
Journal Article
Kozlova, E. V., Hegde, S., Roundy, C. M., Golovko, G., Saldaña, M. A., Hart, C. E., …Hughes, G. L. (2021). Microbial interactions in the mosquito gut determine Serratia colonization and blood-feeding propensity. ISME Journal, 15(1), 93-108. https://doi.org/10.1038/s41396-020-00763-3

How microbe–microbe interactions dictate microbial complexity in the mosquito gut is unclear. Previously we found that, Serratia, a gut symbiont that alters vector competence and is being considered for vector control, poorly colonized Aedes aegypti... Read More about Microbial interactions in the mosquito gut determine Serratia colonization and blood-feeding propensity.