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Loss of cytoskeletal proteostasis links dysregulation of cell size and mechanotransduction in mesenchymal stem cell senescence (2022)
Journal Article

ABSTRACT Tissues are maintained by homeostatic feedback mechanisms where cells respond to, but also modify, the chemical and mechanical properties of the surrounding extracellular matrix. Mesenchymal stem cells (MSCs) resident in the marrow niche exp... Read More about Loss of cytoskeletal proteostasis links dysregulation of cell size and mechanotransduction in mesenchymal stem cell senescence.

Physiological Oxygen Causes the Release of Volatile Organic Compounds from Human Pluripotent Stem Cells with Possible Roles in Maintaining Self-Renewal and Pluripotency (2022)
Journal Article

Human pluripotent stem cells (hPSCs) have widespread potential biomedical applications. There is a need for large-scale in vitro production of hPSCs, and optimal culture methods are vital in achieving this. Physiological oxygen (2% O2) improves key h... Read More about Physiological Oxygen Causes the Release of Volatile Organic Compounds from Human Pluripotent Stem Cells with Possible Roles in Maintaining Self-Renewal and Pluripotency.

Do disasters trigger protests? A conceptual view and review of the connection between disasters, injustice, and protests – the case of COVID-19 (2021)
Other

People around the globe were and are affected by the highly contagious virus SARS-CoV-2 (Coronavirus, COVID-19) far beyond the virus itself. Despite the high viral transmission, people did not stop acting collectively. Sometimes these collective acti... Read More about Do disasters trigger protests? A conceptual view and review of the connection between disasters, injustice, and protests – the case of COVID-19.

Blood biochemical parameters as predictors of disease severity and mortality in COVID-19 patients- an updated systematic review and meta-analysis (2021)
Other

ABSTRACT Background The outbreak of coronavirus disease 2019 (COVID-19) has been rapidly spreading across the globe and poses a great risk to human health. Patients with abnormalities in laboratory parameters are more susceptible to COVID-19. Therefo... Read More about Blood biochemical parameters as predictors of disease severity and mortality in COVID-19 patients- an updated systematic review and meta-analysis.

Propranolol Reduces Risk of Knee or Hip Replacement Due to Osteoarthritis: a Propensity Score Matched Cohort Study-using Data From the Clinical Practice Research Datalink. (2021)
Journal Article

Objectives: To examine the association between ß -blocker prescription and knee or hip total joint replacement (TJR) in a UK primary-care population with incident knee or hip osteoarthritis (OA). Methods: Cohort study using data from the Clinical P... Read More about Propranolol Reduces Risk of Knee or Hip Replacement Due to Osteoarthritis: a Propensity Score Matched Cohort Study-using Data From the Clinical Practice Research Datalink..

Novel HumanMethylatyion450 Analyses Reveal DNA Methylation Predictors of Future Diabetes Onset in Women With Polycystic Ovarian Syndrome (2021)
Journal Article

Aims. Polycystic ovarian syndrome (PCOS) is a common endocrine disorder characterised by ovarian morphological, systemic biochemical, and menstrual changes. Women with PCOS are at significantly increased risk of raised fasting glucose, impaired gluc... Read More about Novel HumanMethylatyion450 Analyses Reveal DNA Methylation Predictors of Future Diabetes Onset in Women With Polycystic Ovarian Syndrome.