Skip to main content

Research Repository

Advanced Search

Equatorial Enhancement in the Dustiest OH/IR Stars in the Galactic Bulge (2025)
Journal Article
Goldman, S. R., van Loon, J. T., Jones, O. C., Blommaert, J. A. D. L., & Groenewegen, M. A. T. (2025). Equatorial Enhancement in the Dustiest OH/IR Stars in the Galactic Bulge. Astrophysical Journal, 980(2), 191. https://doi.org/10.3847/1538-4357/ada6ad

We have detected the 10 μm silicate feature and the 11.3 μm crystalline forsterite feature in absorption in 21 oxygen-rich asymptotic giant branch stars in the Galactic bulge. The depths of the 10 μm feature indicate highly obscured circumstellar env... Read More about Equatorial Enhancement in the Dustiest OH/IR Stars in the Galactic Bulge.

Age-stratified effects of intravenous ferric derisomaltose in heart failure with iron deficiency: insights from the IRONMAN trial (2025)
Journal Article
Sze, S., Squire, I., Kalra, P. R., Cleland, J. G., Petrie, M. C., Kalra, P. A., …Ford, I. (2025). Age-stratified effects of intravenous ferric derisomaltose in heart failure with iron deficiency: insights from the IRONMAN trial. Heart, heartjnl-2024-324908. https://doi.org/10.1136/heartjnl-2024-324908

Background: Intravenous iron therapy with ferric derisomaltose (FDI) has been shown to improve outcomes in patients with heart failure with reduced ejection fraction (HFrEF) and iron deficiency. However, its effects across different age groups remain... Read More about Age-stratified effects of intravenous ferric derisomaltose in heart failure with iron deficiency: insights from the IRONMAN trial.

Bacterial polysaccharide lyase family 33: Specificity from an evolutionarily conserved binding tunnel (2025)
Journal Article
Loiodice, M., Drula, E., McIver, Z., Antonyuk, S., Baslé, A., Lima, M., …Cartmell, A. (2025). Bacterial polysaccharide lyase family 33: Specificity from an evolutionarily conserved binding tunnel. Proceedings of the National Academy of Sciences, 122(7), e2421623122. https://doi.org/10.1073/pnas.2421623122

Acidic glycans are essential for the biology of multicellular eukaryotes. To utilize them, microbial life including symbionts and pathogens has evolved polysaccharide lyases (PL) that cleave their 1,4 glycosidic linkages via a β-elimination mechanism... Read More about Bacterial polysaccharide lyase family 33: Specificity from an evolutionarily conserved binding tunnel.

Understanding women from ethnic minorities’ perspectives about contraception in the UK: a qualitative study using a participatory action research approach with community research link workers (2025)
Journal Article
Linton, E., Mawson, R. L., Cory, R. J., Ma, R., Fryer, K., Aminu, H., …Mitchell, C. A. (2025). Understanding women from ethnic minorities’ perspectives about contraception in the UK: a qualitative study using a participatory action research approach with community research link workers. BMJ Sexual & Reproductive Health, bmjsrh-2024-202522. https://doi.org/10.1136/bmjsrh-2024-202522

Background: Contraception has revolutionised women’s health, enabling planned pregnancies and improved outcomes for mothers and babies. However, disparities exist in rates of unintended pregnancies and contraceptive uptake among ethnic groups. The re... Read More about Understanding women from ethnic minorities’ perspectives about contraception in the UK: a qualitative study using a participatory action research approach with community research link workers.

Proteomic profiling of human plasma and intervertebral disc tissue reveals matrisomal, but not plasma, biomarkers of disc degeneration (2025)
Journal Article
Dube, C. T., Gilbert, H. T. J., Rabbitte, N., Baird, P., Patel, S., Herrera, J. A., …Richardson, S. M. (2025). Proteomic profiling of human plasma and intervertebral disc tissue reveals matrisomal, but not plasma, biomarkers of disc degeneration. Arthritis Research and Therapy, 27(1), Article 28. https://doi.org/10.1186/s13075-025-03489-9

Background: Intervertebral disc (IVD) degeneration is a common cause of low back pain, and the most symptomatic patients with neural compression need surgical intervention to relieve symptoms. Current techniques used to diagnose IVD degeneration, suc... Read More about Proteomic profiling of human plasma and intervertebral disc tissue reveals matrisomal, but not plasma, biomarkers of disc degeneration.

Sleep problems were unrelated to social media use in the late COVID-19 pandemic phase: A cross-national study (2025)
Journal Article
Bonsaksen, T., Price, D., Lamph, G., Kabelenga, I., & Østertun Geirdal, A. (in press). Sleep problems were unrelated to social media use in the late COVID-19 pandemic phase: A cross-national study. PloS one, 20(1), Article e0318507. https://doi.org/10.1371/journal.pone.0318507

Sleep problems are commonly related to stress and mental health problems. However, social media use has become widespread in the general population during recent years, and their addictive potential may influence people’s sleep routine. In addition,... Read More about Sleep problems were unrelated to social media use in the late COVID-19 pandemic phase: A cross-national study.

Temperature-controlled Ablation Versus Conventional Ablation for Pulmonary Vein Isolation in the Treatment of AF: A Systematic Review and Meta-Analysis (2025)
Journal Article
Clay, B., Sokhal, B. S., Zeriouh, S., Srinivasan, N. T., Gajendragadkar, P. R., & Martin, C. A. (2025). Temperature-controlled Ablation Versus Conventional Ablation for Pulmonary Vein Isolation in the Treatment of AF: A Systematic Review and Meta-Analysis. Arrhythmia and Electrophysiology Review, 14, https://doi.org/10.15420/aer.2024.41

Background: This study compared the efficacy and safety of temperature-controlled and conventional contact-force-sensing radiofrequency ablation catheters for pulmonary vein isolation (PVI) in AF. Methods: Seven studies (1,138 patients) were included... Read More about Temperature-controlled Ablation Versus Conventional Ablation for Pulmonary Vein Isolation in the Treatment of AF: A Systematic Review and Meta-Analysis.

On the nonlinear link between stigma and collective action: Evidence from sexual and gender minorities in 25 countries (2025)
Journal Article
Selvanathan, H. P., Valdenegro, D., Noor, M., Visintin, E. P., Lalot, F., Sainz, M., …Hässler, T. (2025). On the nonlinear link between stigma and collective action: Evidence from sexual and gender minorities in 25 countries. Group Processes & Intergroup Relations, https://doi.org/10.1177/13684302241309539

The stigma faced by gender and sexual minorities varies across countries. How does stigma relate to collective action for social change? We propose a curvilinear link (i.e., an inverted U-curve) between stigma and collective action such that increase... Read More about On the nonlinear link between stigma and collective action: Evidence from sexual and gender minorities in 25 countries.

How does organisational culture facilitate uptake of home dialysis? An ethnographic study of kidney centres in England (2024)
Journal Article
Allen, K., Shaw, K. L., Spry, J. L., Dikomitis, L., Coyle, D., Damery, S., …Davies, S. (2024). How does organisational culture facilitate uptake of home dialysis? An ethnographic study of kidney centres in England. BMJ Open, 14(12), https://doi.org/10.1136/bmjopen-2024-085754

Objective: The proportion of people having home dialysis for kidney disease varies considerably by treating centre, socioeconomic deprivation levels in the area and to some extent ethnicity. This study aimed to gain in-depth insights into cultural an... Read More about How does organisational culture facilitate uptake of home dialysis? An ethnographic study of kidney centres in England.

Genotype‐Guided Asthma Treatment Reduces Exacerbations in Children: Meta‐Analysis of Two RCTs (2024)
Journal Article
Slob, E. M. A., Vijverberg, S. J. H., Ruffles, T., Noij, L. C. E., Biermann, J., Brouwer, A. F. J., …Maitland‐van der Zee, A. H. (in press). Genotype‐Guided Asthma Treatment Reduces Exacerbations in Children: Meta‐Analysis of Two RCTs. Allergy, https://doi.org/10.1111/all.16438

Background: Long‐acting beta2‐agonists (LABA) in combination with inhaled corticosteroids (ICS) are commonly used to treat asthma, however, some children lack response to the addition of LABA. This might be partially due to the presence of the Arg16G... Read More about Genotype‐Guided Asthma Treatment Reduces Exacerbations in Children: Meta‐Analysis of Two RCTs.

How do patients determine when their inhaler is empty? Insights from an analysis of returned inhalers and a patient survey. (2024)
Journal Article
Murphy, A. C., Carroll, W., Gotsell, M., Potter, C., Quint, J. K., & Malone, R. (in press). How do patients determine when their inhaler is empty? Insights from an analysis of returned inhalers and a patient survey. BMJ Open Respiratory Research, 11(1), e002579. https://doi.org/10.1136/bmjresp-2024-002579

Inhalers are widely used for the management of asthma and chronic obstructive pulmonary disease. However, there is little knowledge about the extent to which an inhaler is used and when it is disposed of, despite the implications for an individual's... Read More about How do patients determine when their inhaler is empty? Insights from an analysis of returned inhalers and a patient survey..

Rising mortality rates linked to type‐2 diabetes and obesity in the United States: An observational analysis from 1999 to 2022 (2024)
Journal Article
Ahmed, M., Nofal, A., Shafiq, A., Javaid, H., Ahsan, A., Nadeem, Z. A., …Fonarow, G. C. (in press). Rising mortality rates linked to type‐2 diabetes and obesity in the United States: An observational analysis from 1999 to 2022. Journal of Diabetes Investigation, https://doi.org/10.1111/jdi.14386

Background: The prevalence of type 2 diabetes (T2D) and obesity are increasing in the United States. However, population‐level data for mortality trends due to T2D and obesity are limited. This study aims to assess these death trends among adults in... Read More about Rising mortality rates linked to type‐2 diabetes and obesity in the United States: An observational analysis from 1999 to 2022.

A deep learning framework deploying segment anything to detect pan-cancer mitotic figures from haematoxylin and eosin-stained slides (2024)
Journal Article
Shen, Z., Simard, M., Brand, D., Andrei, V., Al-Khader, A., Oumlil, F., …Collins-Fekete, C.-A. (in press). A deep learning framework deploying segment anything to detect pan-cancer mitotic figures from haematoxylin and eosin-stained slides. Communications Biology, 7(1), 1674. https://doi.org/10.1038/s42003-024-07398-6

Mitotic activity is an important feature for grading several cancer types. However, counting mitotic figures (cells in division) is a time-consuming and laborious task prone to inter-observer variation. Inaccurate recognition of MFs can lead to incor... Read More about A deep learning framework deploying segment anything to detect pan-cancer mitotic figures from haematoxylin and eosin-stained slides.

Investigating the accuracy of adjusting for examiner differences in multi-centre Objective Structured Clinical Exams (OSCEs). A simulation study of video-based Examiner Score Comparison and Adjustment (VESCA) (2024)
Journal Article
Yeates, P., & McCray, G. (in press). Investigating the accuracy of adjusting for examiner differences in multi-centre Objective Structured Clinical Exams (OSCEs). A simulation study of video-based Examiner Score Comparison and Adjustment (VESCA). BMC Medical Education, 24(1), 1466. https://doi.org/10.1186/s12909-024-06462-3

Introduction: Ensuring examiner equivalence across distributed assessment locations is a priority within distributed Objective Structured Clinical Exams (OSCEs) but is challenging as examiners are typically fully nested within locations (i.e. no over... Read More about Investigating the accuracy of adjusting for examiner differences in multi-centre Objective Structured Clinical Exams (OSCEs). A simulation study of video-based Examiner Score Comparison and Adjustment (VESCA).

Similar efficacy of intra-articular hyaluronic acid injections and other biologically active injections in patients with early stages knee osteoarthritis: a level I meta-analysis. (2024)
Journal Article
Migliorini, F., Schäfer, L., Pilone, M., Bell, A., Simeone, F., & Maffulli, N. (in press). Similar efficacy of intra-articular hyaluronic acid injections and other biologically active injections in patients with early stages knee osteoarthritis: a level I meta-analysis. Archives of Orthopaedic and Trauma Surgery, 145(1), 68. https://doi.org/10.1007/s00402-024-05614-w

The present meta-analysis compared the efficacy of intra-articular hyaluronic acid (HA) injections in patients with early to mild knee osteoarthritis (OA) (Kellgren Lawrence I-II) versus other commonly injected biologically active compounds using pat... Read More about Similar efficacy of intra-articular hyaluronic acid injections and other biologically active injections in patients with early stages knee osteoarthritis: a level I meta-analysis..

Diagnosing and managing patients with heart failure with preserved ejection fraction: a consensus survey (2024)
Journal Article
Austin, R., Khair, E., Blakeman, T., Hossain, M. Z., Sowden, E., Chew-Graham, C., …Deaton, C. (2024). Diagnosing and managing patients with heart failure with preserved ejection fraction: a consensus survey. BMJ Open, 14(12), bmjopen-2024-092993. https://doi.org/10.1136/bmjopen-2024-092993

Aim: As heart failure (HF) with preserved ejection fraction (HFpEF) prevalence increases, it remains frequently underdiagnosed and poorly managed. Recent positive pharmacological trials have increased interest in HFpEF but challenges of diagnosis and... Read More about Diagnosing and managing patients with heart failure with preserved ejection fraction: a consensus survey.

Integrin adhesome axis inhibits the RPM-1 ubiquitin ligase signaling hub to regulate growth cone and axon development (2024)
Journal Article
Amezquita, J., Desbois, M., Opperman, K. J., Pak, J. S., Christensen, E. L., Nguyen, N. T., …Grill, B. (2024). Integrin adhesome axis inhibits the RPM-1 ubiquitin ligase signaling hub to regulate growth cone and axon development. PLOS genetics, 20(12), Article e1011496. https://doi.org/10.1371/journal.pgen.1011496

Integrin signaling plays important roles in development and disease. An adhesion signaling network called the integrin adhesome has been principally defined using bioinformatics and cell-based proteomics. To date, the adhesome has not been studied us... Read More about Integrin adhesome axis inhibits the RPM-1 ubiquitin ligase signaling hub to regulate growth cone and axon development.

Stellar Evolution and Convection in 3D Hydrodynamic Simulations of a Complete Burning Phase (2024)
Journal Article
Rizzuti, F., Hirschi, R., Varma, V., Arnett, W. D., Georgy, C., Meakin, C., …Rauscher, T. (in press). Stellar Evolution and Convection in 3D Hydrodynamic Simulations of a Complete Burning Phase. Galaxies, 12(6), 87. https://doi.org/10.3390/galaxies12060087

Our understanding of stellar evolution and nucleosynthesis is limited by the uncertainties coming from the complex multi-dimensional processes in stellar interiors, such as convection and nuclear burning. Three-dimensional stellar models can improve... Read More about Stellar Evolution and Convection in 3D Hydrodynamic Simulations of a Complete Burning Phase.

Synthesis of S-Glycoside Building Blocks as Mimetics of the Repeating d-GlcN-α-1,4-d-GlcA Heparan Sulfate Disaccharide (2024)
Journal Article
O’Shea, C., & Miller, G. J. (2024). Synthesis of S-Glycoside Building Blocks as Mimetics of the Repeating d-GlcN-α-1,4-d-GlcA Heparan Sulfate Disaccharide. Molecules, 29(23), Article 5809. https://doi.org/10.3390/molecules29235809

Heparan sulfate (HS), a sulfated linear carbohydrate that decorates the cell surface and extracellular matrix, is a key regulator of biological processes. Owing to the inherent structural complexity of HS, structure-to-function studies with its ligan... Read More about Synthesis of S-Glycoside Building Blocks as Mimetics of the Repeating d-GlcN-α-1,4-d-GlcA Heparan Sulfate Disaccharide.

Metformin for the Prevention of Antipsychotic-Induced Weight Gain: Guideline Development and Consensus Validation (2024)
Journal Article
Carolan, A., Hynes-Ryan, C., Agarwal, S. M., Bourke, R., Cullen, W., Gaughran, F., …O’Donoghue, B. (in press). Metformin for the Prevention of Antipsychotic-Induced Weight Gain: Guideline Development and Consensus Validation. Schizophrenia Bulletin, https://doi.org/10.1093/schbul/sbae205

Background Overweight and obesity are highly prevalent in people with severe mental illness (SMI). Antipsychotic-induced weight gain (AIWG) is one of the most commonly reported and distressing side effects of treatment and people living with SMI plac... Read More about Metformin for the Prevention of Antipsychotic-Induced Weight Gain: Guideline Development and Consensus Validation.