How does organisational culture facilitate uptake of home dialysis? An ethnographic study of kidney centres in England (2024)
Journal Article
Allen, K., Shaw, K. L., Spry, J. L., Dikomitis, L., Coyle, D., Damery, S., …Davies, S. (2024). How does organisational culture facilitate uptake of home dialysis? An ethnographic study of kidney centres in England. BMJ Open, 14(12), https://doi.org/10.1136/bmjopen-2024-085754

Objective: The proportion of people having home dialysis for kidney disease varies considerably by treating centre, socioeconomic deprivation levels in the area and to some extent ethnicity. This study aimed to gain in-depth insights into cultural an... Read More about How does organisational culture facilitate uptake of home dialysis? An ethnographic study of kidney centres in England.

Genotype‐Guided Asthma Treatment Reduces Exacerbations in Children: Meta‐Analysis of Two RCTs (2024)
Journal Article
Slob, E. M. A., Vijverberg, S. J. H., Ruffles, T., Noij, L. C. E., Biermann, J., Brouwer, A. F. J., …Maitland‐van der Zee, A. H. (in press). Genotype‐Guided Asthma Treatment Reduces Exacerbations in Children: Meta‐Analysis of Two RCTs. Allergy, https://doi.org/10.1111/all.16438

Background: Long‐acting beta2‐agonists (LABA) in combination with inhaled corticosteroids (ICS) are commonly used to treat asthma, however, some children lack response to the addition of LABA. This might be partially due to the presence of the Arg16G... Read More about Genotype‐Guided Asthma Treatment Reduces Exacerbations in Children: Meta‐Analysis of Two RCTs.

How do patients determine when their inhaler is empty? Insights from an analysis of returned inhalers and a patient survey. (2024)
Journal Article
Murphy, A. C., Carroll, W., Gotsell, M., Potter, C., Quint, J. K., & Malone, R. (in press). How do patients determine when their inhaler is empty? Insights from an analysis of returned inhalers and a patient survey. BMJ Open Respiratory Research, 11(1), e002579. https://doi.org/10.1136/bmjresp-2024-002579

Inhalers are widely used for the management of asthma and chronic obstructive pulmonary disease. However, there is little knowledge about the extent to which an inhaler is used and when it is disposed of, despite the implications for an individual's... Read More about How do patients determine when their inhaler is empty? Insights from an analysis of returned inhalers and a patient survey..

Rising mortality rates linked to type‐2 diabetes and obesity in the United States: An observational analysis from 1999 to 2022 (2024)
Journal Article
Ahmed, M., Nofal, A., Shafiq, A., Javaid, H., Ahsan, A., Nadeem, Z. A., …Fonarow, G. C. (in press). Rising mortality rates linked to type‐2 diabetes and obesity in the United States: An observational analysis from 1999 to 2022. Journal of Diabetes Investigation, https://doi.org/10.1111/jdi.14386

Background: The prevalence of type 2 diabetes (T2D) and obesity are increasing in the United States. However, population‐level data for mortality trends due to T2D and obesity are limited. This study aims to assess these death trends among adults in... Read More about Rising mortality rates linked to type‐2 diabetes and obesity in the United States: An observational analysis from 1999 to 2022.

A deep learning framework deploying segment anything to detect pan-cancer mitotic figures from haematoxylin and eosin-stained slides (2024)
Journal Article
Shen, Z., Simard, M., Brand, D., Andrei, V., Al-Khader, A., Oumlil, F., …Collins-Fekete, C.-A. (in press). A deep learning framework deploying segment anything to detect pan-cancer mitotic figures from haematoxylin and eosin-stained slides. Communications Biology, 7(1), 1674. https://doi.org/10.1038/s42003-024-07398-6

Mitotic activity is an important feature for grading several cancer types. However, counting mitotic figures (cells in division) is a time-consuming and laborious task prone to inter-observer variation. Inaccurate recognition of MFs can lead to incor... Read More about A deep learning framework deploying segment anything to detect pan-cancer mitotic figures from haematoxylin and eosin-stained slides.

Investigating the accuracy of adjusting for examiner differences in multi-centre Objective Structured Clinical Exams (OSCEs). A simulation study of video-based Examiner Score Comparison and Adjustment (VESCA) (2024)
Journal Article
Yeates, P., & McCray, G. (in press). Investigating the accuracy of adjusting for examiner differences in multi-centre Objective Structured Clinical Exams (OSCEs). A simulation study of video-based Examiner Score Comparison and Adjustment (VESCA). BMC Medical Education, 24(1), 1466. https://doi.org/10.1186/s12909-024-06462-3

Introduction: Ensuring examiner equivalence across distributed assessment locations is a priority within distributed Objective Structured Clinical Exams (OSCEs) but is challenging as examiners are typically fully nested within locations (i.e. no over... Read More about Investigating the accuracy of adjusting for examiner differences in multi-centre Objective Structured Clinical Exams (OSCEs). A simulation study of video-based Examiner Score Comparison and Adjustment (VESCA).

Similar efficacy of intra-articular hyaluronic acid injections and other biologically active injections in patients with early stages knee osteoarthritis: a level I meta-analysis. (2024)
Journal Article
Migliorini, F., Schäfer, L., Pilone, M., Bell, A., Simeone, F., & Maffulli, N. (in press). Similar efficacy of intra-articular hyaluronic acid injections and other biologically active injections in patients with early stages knee osteoarthritis: a level I meta-analysis. Archives of Orthopaedic and Trauma Surgery, 145(1), 68. https://doi.org/10.1007/s00402-024-05614-w

The present meta-analysis compared the efficacy of intra-articular hyaluronic acid (HA) injections in patients with early to mild knee osteoarthritis (OA) (Kellgren Lawrence I-II) versus other commonly injected biologically active compounds using pat... Read More about Similar efficacy of intra-articular hyaluronic acid injections and other biologically active injections in patients with early stages knee osteoarthritis: a level I meta-analysis..

Diagnosing and managing patients with heart failure with preserved ejection fraction: a consensus survey (2024)
Journal Article
Austin, R., Khair, E., Blakeman, T., Hossain, M. Z., Sowden, E., Chew-Graham, C., …Deaton, C. (2024). Diagnosing and managing patients with heart failure with preserved ejection fraction: a consensus survey. BMJ Open, 14(12), bmjopen-2024-092993. https://doi.org/10.1136/bmjopen-2024-092993

Aim: As heart failure (HF) with preserved ejection fraction (HFpEF) prevalence increases, it remains frequently underdiagnosed and poorly managed. Recent positive pharmacological trials have increased interest in HFpEF but challenges of diagnosis and... Read More about Diagnosing and managing patients with heart failure with preserved ejection fraction: a consensus survey.

Integrin adhesome axis inhibits the RPM-1 ubiquitin ligase signaling hub to regulate growth cone and axon development (2024)
Journal Article
Amezquita, J., Desbois, M., Opperman, K. J., Pak, J. S., Christensen, E. L., Nguyen, N. T., …Grill, B. (2024). Integrin adhesome axis inhibits the RPM-1 ubiquitin ligase signaling hub to regulate growth cone and axon development. PLOS genetics, 20(12), Article e1011496. https://doi.org/10.1371/journal.pgen.1011496

Integrin signaling plays important roles in development and disease. An adhesion signaling network called the integrin adhesome has been principally defined using bioinformatics and cell-based proteomics. To date, the adhesome has not been studied us... Read More about Integrin adhesome axis inhibits the RPM-1 ubiquitin ligase signaling hub to regulate growth cone and axon development.

Stellar Evolution and Convection in 3D Hydrodynamic Simulations of a Complete Burning Phase (2024)
Journal Article
Rizzuti, F., Hirschi, R., Varma, V., Arnett, W. D., Georgy, C., Meakin, C., …Rauscher, T. (in press). Stellar Evolution and Convection in 3D Hydrodynamic Simulations of a Complete Burning Phase. Galaxies, 12(6), 87. https://doi.org/10.3390/galaxies12060087

Our understanding of stellar evolution and nucleosynthesis is limited by the uncertainties coming from the complex multi-dimensional processes in stellar interiors, such as convection and nuclear burning. Three-dimensional stellar models can improve... Read More about Stellar Evolution and Convection in 3D Hydrodynamic Simulations of a Complete Burning Phase.

Near-infrared spectroscopy of the LMC recurrent nova LMCN 1968-12a (2024)
Journal Article
Evans, A., Banerjee, D. P. K., Geballe, T. R., Polin, A., Hsiao, E. Y., Page, K. L., …Starrfield, S. (2024). Near-infrared spectroscopy of the LMC recurrent nova LMCN 1968-12a. Monthly Notices of the Royal Astronomical Society, 536(2), 1710-1717. https://doi.org/10.1093/mnras/stae2711

We have obtained near-infrared (0.80–2.45 $\, \mu$m) spectra of the recurrent nova LMCN 1968-12a on two occasions during its 2024 August eruption. This is the first near-infrared spectroscopy of an extragalactic nova. The initial spectrum, on day 8.4... Read More about Near-infrared spectroscopy of the LMC recurrent nova LMCN 1968-12a.

Synthesis of S-Glycoside Building Blocks as Mimetics of the Repeating d-GlcN-α-1,4-d-GlcA Heparan Sulfate Disaccharide (2024)
Journal Article
O’Shea, C., & Miller, G. J. (2024). Synthesis of S-Glycoside Building Blocks as Mimetics of the Repeating d-GlcN-α-1,4-d-GlcA Heparan Sulfate Disaccharide. Molecules, 29(23), Article 5809. https://doi.org/10.3390/molecules29235809

Heparan sulfate (HS), a sulfated linear carbohydrate that decorates the cell surface and extracellular matrix, is a key regulator of biological processes. Owing to the inherent structural complexity of HS, structure-to-function studies with its ligan... Read More about Synthesis of S-Glycoside Building Blocks as Mimetics of the Repeating d-GlcN-α-1,4-d-GlcA Heparan Sulfate Disaccharide.

Metformin for the Prevention of Antipsychotic-Induced Weight Gain: Guideline Development and Consensus Validation (2024)
Journal Article
Carolan, A., Hynes-Ryan, C., Agarwal, S. M., Bourke, R., Cullen, W., Gaughran, F., …O’Donoghue, B. (in press). Metformin for the Prevention of Antipsychotic-Induced Weight Gain: Guideline Development and Consensus Validation. Schizophrenia Bulletin, https://doi.org/10.1093/schbul/sbae205

Background Overweight and obesity are highly prevalent in people with severe mental illness (SMI). Antipsychotic-induced weight gain (AIWG) is one of the most commonly reported and distressing side effects of treatment and people living with SMI plac... Read More about Metformin for the Prevention of Antipsychotic-Induced Weight Gain: Guideline Development and Consensus Validation.

The digital prescription: A systematic review and meta-analysis of smartphone apps for blood pressure control. (2024)
Journal Article
Motta-Yanac, E., Riley, V., Ellis, N. J., Mankoo, A., & Gidlow, C. J. (in press). The digital prescription: A systematic review and meta-analysis of smartphone apps for blood pressure control. International Journal of Medical Informatics, 195, 105755. https://doi.org/10.1016/j.ijmedinf.2024.105755

Assess the effectiveness of digital health interventions (DHIs) in reducing blood pressure (BP) among individuals with high blood pressure and identify the impact of age, sex, and phone-based delivery methods on BP. A systematic review and meta-analy... Read More about The digital prescription: A systematic review and meta-analysis of smartphone apps for blood pressure control..

Temporal Trends in Mortality Related to Stroke and Atrial Fibrillation in the United States: A 21‐Year Retrospective Analysis of CDC‐WONDER Database (2024)
Journal Article
Ahmad, O., Farooqi, H. A., Ahmed, I., Jamil, A., Nabi, R., Ullah, I., …Mamas, M. A. (2024). Temporal Trends in Mortality Related to Stroke and Atrial Fibrillation in the United States: A 21‐Year Retrospective Analysis of CDC‐WONDER Database. Clinical Cardiology, 47(12), e70058. https://doi.org/10.1002/clc.70058

Aims: Atrial Fibrillation (AF) is one of the most strongly associated risk factors for stroke. Our study aims to analyze changes in mortality from 1999 to 2020 in patients with AF and stroke. Methods: Using the Centre for Disease Control and Preventi... Read More about Temporal Trends in Mortality Related to Stroke and Atrial Fibrillation in the United States: A 21‐Year Retrospective Analysis of CDC‐WONDER Database.

Prediction of Distant Metastasis of Lymph-Node-Negative Primary Breast Cancer From Gene Expression Profiling Using Cox-Boost Regression Model (2024)
Journal Article
Hamidi, O., Amini, P., Tapak, L., Zohrab Beigi, Y., Afshar, S., & Dinu, I. (in press). Prediction of Distant Metastasis of Lymph-Node-Negative Primary Breast Cancer From Gene Expression Profiling Using Cox-Boost Regression Model. Cancer Informatics, 23, https://doi.org/10.1177/11769351241297493

Backgrounds:: Distant metastasis in breast cancer patients contributes to increased breast cancer mortality, highlighting the urgent need for effective predictive strategies. Understanding metastasis mechanisms and identifying relevant biomarkers are... Read More about Prediction of Distant Metastasis of Lymph-Node-Negative Primary Breast Cancer From Gene Expression Profiling Using Cox-Boost Regression Model.

No Effect of Cigarette Smoking in the Outcome of Arthroscopic Management for Femoroacetabular Impingement: A Systematic Review (2024)
Journal Article
Lucenti, L., Maffulli, N., Bardazzi, T., Pipino, G., Pappalardo, G., & Migliorini, F. (in press). No Effect of Cigarette Smoking in the Outcome of Arthroscopic Management for Femoroacetabular Impingement: A Systematic Review. Journal of Clinical Medicine, 13(23), https://doi.org/10.3390/jcm13237214

Background: The impact of smoking in arthroscopic surgery for femoroacetabolar impingement (FAI) is controversial. This systematic review updates and discusses current evidence on the influence of cigarette smoking on the outcome of arthroscopic mana... Read More about No Effect of Cigarette Smoking in the Outcome of Arthroscopic Management for Femoroacetabular Impingement: A Systematic Review.

Intra-articular injections of ozone versus hyaluronic acid for knee osteoarthritis: a level I meta-analysis. (2024)
Journal Article
Migliorini, F., Giorgino, R., Mazzoleni, M. G., Schäfer, L., Bertini, F. A., & Maffulli, N. (in press). Intra-articular injections of ozone versus hyaluronic acid for knee osteoarthritis: a level I meta-analysis. European Journal of Orthopaedic Surgery and Traumatology, 35(1), Article 20. https://doi.org/10.1007/s00590-024-04135-x

Intra-articular injections of ozone and hyaluronic acid (HA) are routinely performed for the management of knee osteoarthritis. The present meta-analysis compared intra-articular injections of HA versus ozone in patients with knee osteoarthritis (OA)... Read More about Intra-articular injections of ozone versus hyaluronic acid for knee osteoarthritis: a level I meta-analysis..

Less Pain with Intra-Articular Hyaluronic Acid Injections for Knee Osteoarthritis Compared to Placebo: A Systematic Review and Meta-Analysis of Randomised Controlled Trials (2024)
Journal Article
Migliorini, F., Maffulli, N., Schäfer, L., Kubach, J., Betsch, M., & Pasurka, M. (in press). Less Pain with Intra-Articular Hyaluronic Acid Injections for Knee Osteoarthritis Compared to Placebo: A Systematic Review and Meta-Analysis of Randomised Controlled Trials. Pharmaceuticals, 17(11), Article 1557. https://doi.org/10.3390/ph17111557

The present meta-analysis investigated the efficacy of intra-articular hyaluronic acid (HA) injections for knee osteoarthritis. The outcomes of interest were the visual analogue scale (VAS) and Western Ontario McMaster Osteo-Arthritis Index (WOMAC) s... Read More about Less Pain with Intra-Articular Hyaluronic Acid Injections for Knee Osteoarthritis Compared to Placebo: A Systematic Review and Meta-Analysis of Randomised Controlled Trials.

Emotion Classification on Software Engineering Q&A Websites (2024)
Journal Article
Awovi Ahavi-Tete, D., & Sangeeta, S. (2025). Emotion Classification on Software Engineering Q&A Websites. e-Informatica Software Engineering Journal (EISEJ), 19(1), Article 250104. https://doi.org/10.37190/e-inf250104

Background: With the rapid proliferation of question-and-answer websites for software developers like Stack Overflow, there is an increasing need to discern developers’ emotions from their posts to assess the influence of these emotions on their prod... Read More about Emotion Classification on Software Engineering Q&A Websites.