Neural Cell Interactions with a Surgical Grade Biomaterial Using a Simulated Injury in Brain Organotypic Slices (2024)
Journal Article
Wiseman, J. P., & Chari, D. M. (in press). Neural Cell Interactions with a Surgical Grade Biomaterial Using a Simulated Injury in Brain Organotypic Slices. Journal of Functional Biomaterials, 15(12), Article 362. https://doi.org/10.3390/jfb15120362

Tissue engineering research for neurological applications has demonstrated that biomaterial-based structural bridges present a promising approach for promoting regeneration. This is particularly relevant for penetrating traumatic brain injuries, wher... Read More about Neural Cell Interactions with a Surgical Grade Biomaterial Using a Simulated Injury in Brain Organotypic Slices.

Everyday Living with Osteoarthritis in the Global South: A qualitative focus group inquiry in Nigeria. (2024)
Journal Article
Owoyemi, T., Alonge, I., Adetunji, O., Ogbu, E., Ogunbanjo, A., White, S., …Dziedzic, K. (2024). Everyday Living with Osteoarthritis in the Global South: A qualitative focus group inquiry in Nigeria. Osteoarthritis and Cartilage Open, Article 100555. https://doi.org/10.1016/j.ocarto.2024.100555

Objective
Africa contributes significantly to the increasing global prevalence (>37%), unmet need and treatment burden for people with osteoarthritis. Despite this, little research has examined the expressed needs of patients with osteoarthritis (OA... Read More about Everyday Living with Osteoarthritis in the Global South: A qualitative focus group inquiry in Nigeria..

Architecture of TOI-561 planetary system (2024)
Journal Article
Piotto, G., Zingales, T., Borsato, L., Egger, J. A., Correia, A. C. M., Simon, A. E., …Wolf, S. (in press). Architecture of TOI-561 planetary system. Monthly Notices of the Royal Astronomical Society, 535(3), 2763-2774. https://doi.org/10.1093/mnras/stae2440

We present new observations from CHEOPS (CHaracterising ExOPlanet Satellite) and TESS (Transiting Exoplanet Survey Satellite) to clarify the architecture of the planetary system hosted by the old Galactic thick disc star TOI-561. Our global analysis,... Read More about Architecture of TOI-561 planetary system.

Synthesis of Nucleoside Analogs Containing Sulfur or Selenium Replacements of the Ribose Ring Oxygen or Carbon. (2024)
Journal Article
Benckendorff, C. M. M., Sunde-Brown, P., Ní Cheallaigh, A., & Miller, G. J. (2024). Synthesis of Nucleoside Analogs Containing Sulfur or Selenium Replacements of the Ribose Ring Oxygen or Carbon. Journal of Organic Chemistry, 89(23), 16977-16989. https://doi.org/10.1021/acs.joc.4c02409

Nucleoside analogs have proven highly successful in many pharmaceutical intervention strategies, and continued exploration of next generation structural motifs is required. Herein we discuss recent advances toward the chemical synthesis of heteroatom... Read More about Synthesis of Nucleoside Analogs Containing Sulfur or Selenium Replacements of the Ribose Ring Oxygen or Carbon..

Migratory birds can extract positional information from magnetic inclination and magnetic declination alone (2024)
Journal Article
Packmor, F., Kishkinev, D., Zechmeister, T., Mouritsen, H., & Holland, R. A. (2024). Migratory birds can extract positional information from magnetic inclination and magnetic declination alone. Proceedings of the Royal Society B: Biological Sciences, 291(2034), https://doi.org/10.1098/rspb.2024.1363

Migratory birds are able to navigate over great distances with remarkable accuracy. The mechanism they use to achieve this feat is thought to involve two distinct steps: locating their position (the “map”) and heading towards the direction determi... Read More about Migratory birds can extract positional information from magnetic inclination and magnetic declination alone.

Minimising cybersecurity risk exposures in industrial control system environments: a techno-human vulnerability analysis approach (2024)
Journal Article
Ani, U. D., Watson, J., He, H., Radanliev, P., & Epiphaniou, G. (in press). Minimising cybersecurity risk exposures in industrial control system environments: a techno-human vulnerability analysis approach. Journal of Cyber Security Technology, 1-40. https://doi.org/10.1080/23742917.2024.2421589

Organisations operating IoT-enabled industrial control systems (ICSs) are concerned about growing cybersecurity risks and impacts to their systems. Cyber-attacks on ICSs demonstrate that technology alone is neither a problem nor a solution to the gro... Read More about Minimising cybersecurity risk exposures in industrial control system environments: a techno-human vulnerability analysis approach.

Intra-Articular Injection of Human Umbilical Cord-Derived Mesenchymal Stromal Cells Reduces Radiographic Osteoarthritis in an Ovine Model (2024)
Journal Article
Perry, J., Mennan, C., Cool, P., McCarthy, H., Newell, K., Hopkins, T., …Roberts, S. (2024). Intra-Articular Injection of Human Umbilical Cord-Derived Mesenchymal Stromal Cells Reduces Radiographic Osteoarthritis in an Ovine Model. Cartilage, https://doi.org/10.1177/19476035241287832

Objective
To determine if mesenchymal stromal cells (MSCs) derived from human umbilical cords (hUC) could reduce degeneration developing when injected into the knee of a large animal model of osteoarthritis (OA).
Design
Ten million culture-expande... Read More about Intra-Articular Injection of Human Umbilical Cord-Derived Mesenchymal Stromal Cells Reduces Radiographic Osteoarthritis in an Ovine Model.

Intra-Articular Injection of Human Umbilical Cord-Derived Mesenchymal Stromal Cells Reduces Radiographic Osteoarthritis in an Ovine Model (2024)
Journal Article
Perry, J., Mennan, C., Cool, P., McCarthy, H. S., Newell, K., Hopkins, T., …Roberts, S. (2024). Intra-Articular Injection of Human Umbilical Cord-Derived Mesenchymal Stromal Cells Reduces Radiographic Osteoarthritis in an Ovine Model. Cartilage, https://doi.org/10.1177/19476035241287832

Objective To determine if mesenchymal stromal cells (MSCs) derived from human umbilical cords (hUC) could reduce degeneration developing when injected into the knee of a large animal model of osteoarthritis (OA). Design Ten million culture-expanded U... Read More about Intra-Articular Injection of Human Umbilical Cord-Derived Mesenchymal Stromal Cells Reduces Radiographic Osteoarthritis in an Ovine Model.

A Randomized Controlled Trial Comparing “Early” Versus “Late” Periosteal Patch Attachment to Knee Chondral Defects in Autologous Chondrocyte Implantation (2024)
Journal Article
Orfanos, G., McCarthy, H. S., Williams, M., Dugard, N., Gallacher, P. D., Glover, A. W., …Kuiper, J. H. (2024). A Randomized Controlled Trial Comparing “Early” Versus “Late” Periosteal Patch Attachment to Knee Chondral Defects in Autologous Chondrocyte Implantation. Cartilage, https://doi.org/10.1177/19476035241279943

Objective
Traditional autologous chondrocyte implantation (ACI) involves arthroscopically harvesting a cartilage biopsy (stage 1), followed by arthrotomy 3-4 weeks later to apply a periosteal patch and implant culture-expanded chondrocytes underneat... Read More about A Randomized Controlled Trial Comparing “Early” Versus “Late” Periosteal Patch Attachment to Knee Chondral Defects in Autologous Chondrocyte Implantation.

Low-frequency propagating and evanescent waves in strongly inhomogeneous sandwich plates (2024)
Journal Article
Prikazchikova, L., Rege, A., Kaplunov, J., & Prikazchikov, D. (2024). Low-frequency propagating and evanescent waves in strongly inhomogeneous sandwich plates. Zeitschrift für angewandte Mathematik und Physik, 75, 1-14. https://doi.org/10.1007/s00033-024-02347-z

The paper aims at studying dispersion of elastic waves in a sandwich plate with the parameters, characteristic of aerogel core and hard skin layers, typical for aerospace applications including optimal design of fuselage structural components. The pr... Read More about Low-frequency propagating and evanescent waves in strongly inhomogeneous sandwich plates.

Fast Generation of Custom Floating-Point Spatial Filters on FPGAs (2024)
Journal Article
Campos, N., Edirisinghe, E., Chesnokov, S., & Larkin, D. (2024). Fast Generation of Custom Floating-Point Spatial Filters on FPGAs. IEEE Access, 12, 167059-167071. https://doi.org/10.1109/access.2024.3486066

Convolutional Neural Networks (CNNs) have been utilised in many image and video processing applications. The convolution operator, also known as a spatial filter, is usually a linear operation, but this linearity compromises essential features and de... Read More about Fast Generation of Custom Floating-Point Spatial Filters on FPGAs.

Rapid screening for resistance to Sitobion avenae (F.) and Rhopalosiphum padi (L.) in winter wheat seedlings and selection of efficient assessment methods (2024)
Journal Article
Qonaah, I. A., Simon, A. L., Warner, D., Rostron, R. M., Bruce, T. J. A., & Ray, R. V. (in press). Rapid screening for resistance to Sitobion avenae (F.) and Rhopalosiphum padi (L.) in winter wheat seedlings and selection of efficient assessment methods. Pest Management Science, 1-12. https://doi.org/10.1002/ps.8485

BACKGROUND: Sitobion avenae (F.) and Rhopalosiphum padi (L.) are harmful pests of wheat [Triticum aestivum (L.)]. No genetic resistance against the aphids has been identified in commercial wheat varieties and resistance phenotyping can be time‐consum... Read More about Rapid screening for resistance to Sitobion avenae (F.) and Rhopalosiphum padi (L.) in winter wheat seedlings and selection of efficient assessment methods.

Molecular characterization of reassortant infectious bursal disease virus (IBDV) strains of genogroup A3B1 detected in some areas of Britain between 2020 and 2021. (2024)
Journal Article
Reddy, V. R. A. P., Bianco, C., Poulos, C., Egana-Labrin, S. C., Brodrick, A. J., Nazki, S., …Broadbent, A. J. (in press). Molecular characterization of reassortant infectious bursal disease virus (IBDV) strains of genogroup A3B1 detected in some areas of Britain between 2020 and 2021. Virology, 600, Article 110269. https://doi.org/10.1016/j.virol.2024.110269

Infectious bursal disease virus (IBDV) causes a major immunosuppressive disease of chickens. As part of ongoing epidemiological surveillance for IBDV, the hypervariable region (HVR) of the VP2 capsid gene encoded by segment A, and a region of the VP1... Read More about Molecular characterization of reassortant infectious bursal disease virus (IBDV) strains of genogroup A3B1 detected in some areas of Britain between 2020 and 2021..

A genome-wide association analysis reveals new pathogenic pathways in gout. (2024)
Journal Article
Major, T. J., Takei, R., Matsuo, H., Leask, M. P., Sumpter, N. A., Topless, R. K., …Merriman, T. R. (in press). A genome-wide association analysis reveals new pathogenic pathways in gout. Nature Genetics, https://doi.org/10.1038/s41588-024-01921-5

Gout is a chronic disease that is caused by an innate immune response to deposited monosodium urate crystals in the setting of hyperuricemia. Here, we provide insights into the molecular mechanism of the poorly understood inflammatory component of go... Read More about A genome-wide association analysis reveals new pathogenic pathways in gout..

Exercise, disease state and sex influence the beneficial effects of Fn14-depletion on survival and muscle pathology in the SOD1G93A amyotrophic lateral sclerosis (ALS) mouse model (2024)
Journal Article
Hazell, G., McCallion, E., Ahlskog, N., Sutton, E. R., Okoh, M., Shaqoura, E. I. H., …Bowerman, M. (in press). Exercise, disease state and sex influence the beneficial effects of Fn14-depletion on survival and muscle pathology in the SOD1G93A amyotrophic lateral sclerosis (ALS) mouse model. Skeletal Muscle, 14(1), Article 23. https://doi.org/10.1186/s13395-024-00356-0

Background: Amyotrophic lateral sclerosis (ALS) is a devastating and incurable neurodegenerative disease. Accumulating evidence strongly suggests that intrinsic muscle defects exist and contribute to disease progression, including imbalances in whole... Read More about Exercise, disease state and sex influence the beneficial effects of Fn14-depletion on survival and muscle pathology in the SOD1G93A amyotrophic lateral sclerosis (ALS) mouse model.

Wrinkling of differentially growing bilayers with similar film and substrate moduli (2024)
Journal Article
Shen, J., Fu, Y., Pirrera, A., & Groh, R. M. (2024). Wrinkling of differentially growing bilayers with similar film and substrate moduli. Journal of the Mechanics and Physics of Solids, 193, Article 105900. https://doi.org/10.1016/j.jmps.2024.105900

Growth-induced surface wrinkling in constrained bilayers comprising a thin film attached to a thick substrate is a canonical model for understanding pattern formation in many biological systems. While the bilayer model has received much prior attenti... Read More about Wrinkling of differentially growing bilayers with similar film and substrate moduli.

AI security and cyber risk in IoT systems (2024)
Journal Article
Radanliev, P., De Roure, D., Maple, C., Nurse, J. R. C., Nicolescu, R., & Ani, U. (in press). AI security and cyber risk in IoT systems. Frontiers in Big Data, 7, Article 1402745. https://doi.org/10.3389/fdata.2024.1402745

Internet-of-Things (IoT) refers to low-memory connected devices used in various new technologies, including drones, autonomous machines, and robotics. The article aims to understand better cyber risks in low-memory devices and the challenges in IoT r... Read More about AI security and cyber risk in IoT systems.

BEBOP VI. enabling the detection of circumbinary planets orbiting double-lined binaries with the DOLBY method of radial-velocity extraction (2024)
Journal Article
Sairam, L., Baycroft, T. A., Boisse, I., Heidari, N., Santerne, A., Triaud, A. H. M. J., …Standing, M. R. (in press). BEBOP VI. enabling the detection of circumbinary planets orbiting double-lined binaries with the DOLBY method of radial-velocity extraction. Monthly Notices of the Royal Astronomical Society, 534(4), 3999-4017. https://doi.org/10.1093/mnras/stae2317

Circumbinary planets, orbiting both stars in a binary system, offer the opportunity to study planet formation and orbital migration in an environment different from that around single stars. However, despite the fact that $> 90~{{\%}}$ of binary s... Read More about BEBOP VI. enabling the detection of circumbinary planets orbiting double-lined binaries with the DOLBY method of radial-velocity extraction.

Self-induced transparency of long water waves over bathymetry: the dispersive shock mechanism (2024)
Journal Article
Sheremet, A., Qayyum, R., & Shrira, V. (2024). Self-induced transparency of long water waves over bathymetry: the dispersive shock mechanism. Journal of Fluid Mechanics, 997, https://doi.org/10.1017/jfm.2024.850

The shoreline hazard posed by ocean long waves such as tsunamis and meteotsunamis critically depends on the fraction of energy transmitted across the shallow near-shore shelf. In linear setting, bathymetric inhomogeneities of length comparable to the... Read More about Self-induced transparency of long water waves over bathymetry: the dispersive shock mechanism.

Long COVID and Health Inequalities: What's Next for Research and Policy Advocacy? (2024)
Journal Article
Akhtar Baz, S., Woodrow, M., Clutterbuck, D., Fang, C., Mullard, J., Banerjee, A., …Alwan, N. A. (2024). Long COVID and Health Inequalities: What's Next for Research and Policy Advocacy?. Health Expectations, 27(5), Article e70047. https://doi.org/10.1111/hex.70047

Introduction: Organised by the ‘Qualitative Long Covid Network’, a workshop for qualitative Long COVID (LC) researchers, LC charity representatives and people with LC took place in June 2023, where research on the intersectional inequalities affectin... Read More about Long COVID and Health Inequalities: What's Next for Research and Policy Advocacy?.