Baseline Characteristics of the TOPaZ Study: Randomised Trial of Teriparatide and Zoledronic Acid Compared with Standard Care in Adults with Osteogenesis Imperfecta (2025)
Journal Article
Hald, J. D., Weir, C., Keerie, C., Dewar, L., MacLean, M., Milne, L., Keen, R., Walsh, J., Poole, K., Langdahl, B., Lindsay, J. R., Ghouri, N., Hollick, R. J., Aspray, T., Crowley, R. K., Cohen-Solal, M., Hassan-Smith, Z., Tuck, S., Curtis, E., …Ralston, S. H. (2025). Baseline Characteristics of the TOPaZ Study: Randomised Trial of Teriparatide and Zoledronic Acid Compared with Standard Care in Adults with Osteogenesis Imperfecta. Calcified Tissue International, 116(1), 136. https://doi.org/10.1007/s00223-025-01440-3

Introduction: Osteogenesis imperfecta (OI) is a rare disorder causing multiple fractures throughout life. No treatment has been shown to reduce the risk of fractures in OI. Here, we present the baseline characteristics of participants in the Treatmen... Read More about Baseline Characteristics of the TOPaZ Study: Randomised Trial of Teriparatide and Zoledronic Acid Compared with Standard Care in Adults with Osteogenesis Imperfecta.

Characterising PMP22-Proximal Partners in a Schwann Cell Model of Charcot–Marie–Tooth Disease Type1A (2025)
Journal Article
Holt, I., Emery, N., Gates, M. A., Brown, S. J., Shirran, S. L., & Fuller, H. R. (2025). Characterising PMP22-Proximal Partners in a Schwann Cell Model of Charcot–Marie–Tooth Disease Type1A. Biology, 14(11), 1552. https://doi.org/10.3390/biology14111552

Charcot–Marie–Tooth disease type 1A (CMT1A) is a hereditary condition caused by the duplication of the PMP22 gene. Overexpression of peripheral myelin protein 22 in Schwann cells leads to myelin sheath defects and axonal loss. We have produced a cell... Read More about Characterising PMP22-Proximal Partners in a Schwann Cell Model of Charcot–Marie–Tooth Disease Type1A.

Trans-Fe elements from type Ia supernovae (2025)
Journal Article
Battino, U., Keegans, J. D., Allen, M., Röpke, F. K., Herwig, F., Best, A., Hirschi, R., Piersanti, L., Straniero, O., Sim, S. A., Travaglio, C., & Denissenkov, P. A. (2025). Trans-Fe elements from type Ia supernovae. Astronomy & Astrophysics, 703(November 2025), A44. https://doi.org/10.1051/0004-6361/202555745

Context. A type Ia supernova (SNIa) marks the catastrophic explosion of a white dwarf in a binary system. These events play a crucial role in galactic chemical evolution and serve as pivotal standardisable candles for measuring cosmic distances, unde... Read More about Trans-Fe elements from type Ia supernovae.

Staffordshire Green Skills for Growth: Post-16 education provider green course provision (2025)
Report
Robinson, Z., Sissons, P., Bedford, T., & Langley, R. (2025, October 31). Staffordshire Green Skills for Growth: Post-16 education provider green course provision. https://keele-repository.worktribe.com/output/1494435

This report explores green skills training provision in post-16 education providers in Staffordshire and Stoke-on-Trent and adjacent areas, as part of the Staffordshire Green Skills for Growth project funded by Innovate UK as part of their Net Zero L... Read More about Staffordshire Green Skills for Growth: Post-16 education provider green course provision.

Fundamental effective temperature measurements for eclipsing binary stars – VI. Improved methodology and application to the circumbinary planet host star BEBOP-3 (2025)
Journal Article
Maxted, P. F. L., Miller, N. J., Baycroft, T. A., Sebastian, D., Triaud, A. H. M. J., & Martin, D. V. (2025). Fundamental effective temperature measurements for eclipsing binary stars – VI. Improved methodology and application to the circumbinary planet host star BEBOP-3. Monthly Notices of the Royal Astronomical Society, staf1856. https://doi.org/10.1093/mnras/staf1856

BEBOP-3 is detached eclipsing binary star that shows total eclipses of a faint M dwarf every 13.2 days by a 9th-magnitude F9 V star. High precision radial velocity measurements have recently shown that this binary star is orbited by a planet with an... Read More about Fundamental effective temperature measurements for eclipsing binary stars – VI. Improved methodology and application to the circumbinary planet host star BEBOP-3.

3D Synthetic Convective Velocity Fields to Initialise Core-Collapse Supernova Simulations from 1D Progenitors (2025)
Journal Article
Varma, V., Müller, B., & Hirschi, R. (2025). 3D Synthetic Convective Velocity Fields to Initialise Core-Collapse Supernova Simulations from 1D Progenitors. Monthly Notices of the Royal Astronomical Society. https://doi.org/10.1093/mnras/staf1860

Core-collapse supernovae (CCSNe) are among the most energetic and complex astrophysical phenomena, requiring three-dimensional (3D) simulations to capture their intricate explosion mechanisms. One of the key ingredients for such simulations is the 3D... Read More about 3D Synthetic Convective Velocity Fields to Initialise Core-Collapse Supernova Simulations from 1D Progenitors.

Spatio‐Temporal Variation in Aerial Arthropod Abundance Revealed by Weather Radars (2025)
Journal Article
Mungee, M., Lukach, M., Shortall, C., Bell, J. R., Duncan, E. J., Addison, F. I., Brown, L. E., Kunin, W. E., Hassall, C., & Neely, R. R. (2025). Spatio‐Temporal Variation in Aerial Arthropod Abundance Revealed by Weather Radars. Global Change Biology, 31(10), e70425. https://doi.org/10.1111/gcb.70425

Arthropod declines have been reported widely; however, a lack of comprehensive data has hindered our ability to assess their large-scale generality and drivers. Here, we used a novel and freely available dataset—atmospheric scans from a network of me... Read More about Spatio‐Temporal Variation in Aerial Arthropod Abundance Revealed by Weather Radars.

Development of a community research link worker role to enable culturally tailored research and empower marginalised communities to participate: the IBISES model (2025)
Journal Article
Fryer, K., Reynolds, J., Huang, Q., Mawson, R., Linton, E., Aminu, H., White, J., Cory, R., & Mitchell, C. (2025). Development of a community research link worker role to enable culturally tailored research and empower marginalised communities to participate: the IBISES model. Research Involvement and Engagement, 11(1), 122. https://doi.org/10.1186/s40900-025-00793-1

Background: People from ethnic minority and socioeconomically deprived backgrounds remain underrepresented in primary healthcare research despite experiencing worse health outcomes and healthcare experiences. Traditional engagement approaches often m... Read More about Development of a community research link worker role to enable culturally tailored research and empower marginalised communities to participate: the IBISES model.

An Ultra-Short Period Super-Earth and Sub-Neptune Spanning the Radius Valley Orbiting the Kinematic Thick Disk Star TOI-2345 (2025)
Journal Article
Eschen, Y. N. E., Wilson, T. G., Bonfanti, A., Persson, C. M., Sousa, S. G., Lendl, M., Heitzmann, A., Simon, A. E., Olofsson, G., Castro-González, A., Egger, J. A., Fossati, L., Mustill, A. J., Osborn, H. P., Vivien, H. G., Alibert, Y., Alonso, R., Bárczy, T., Barrado, D., …Ziegler, C. (2025). An Ultra-Short Period Super-Earth and Sub-Neptune Spanning the Radius Valley Orbiting the Kinematic Thick Disk Star TOI-2345. Monthly Notices of the Royal Astronomical Society, 1-23, staf1806. https://doi.org/10.1093/mnras/staf1806

A crucial chemical link between stars and their orbiting exoplanets is thought to exist. If universal, this connection could affect the formation and evolution of all planets. Therefore, this potential vital link needs testing by characterising exopl... Read More about An Ultra-Short Period Super-Earth and Sub-Neptune Spanning the Radius Valley Orbiting the Kinematic Thick Disk Star TOI-2345.

Extracellular vesicle bioactivity and potential for clinical development are determined by mesenchymal stromal cell clonal subtype (2025)
Journal Article
Ioannou, S., Kay, A. G., Stone, A. P., Rand, E., Elberfeld, S., Bolton, W., Larson, T., Crossland, R. E., Kehoe, O., Mentlak, D. A., Wang, X.-N., MacDonald, C., & Genever, P. G. (2025). Extracellular vesicle bioactivity and potential for clinical development are determined by mesenchymal stromal cell clonal subtype. Stem Cell Research and Therapy, 16(1), 571. https://doi.org/10.1186/s13287-025-04665-z

Background: Mesenchymal stromal cells (MSCs) have been used in numerous clinical trials but very few reach phase 3 or market authorisation. Progress is often hampered by the use of non-clonal, heterogeneous and uncharacterised MSC cultures and lack o... Read More about Extracellular vesicle bioactivity and potential for clinical development are determined by mesenchymal stromal cell clonal subtype.

Host Transcriptomics Reveal Reduction in Defence‐Reproduction Trade‐Offs During Coinfection (2025)
Journal Article
Will, I., Stevens, E. J., King, K. C., & Bates, K. A. (2025). Host Transcriptomics Reveal Reduction in Defence‐Reproduction Trade‐Offs During Coinfection. Molecular Ecology, e70124. https://doi.org/10.1111/mec.70124

During infection, hosts may shift resources away from reproduction towards immune defence. It is unclear to what degree these costly trade‐offs can be alleviated during protective coinfections, whereby antagonism between parasites reduces disease sev... Read More about Host Transcriptomics Reveal Reduction in Defence‐Reproduction Trade‐Offs During Coinfection.

Mifepristone alone and in combination with scAAV9-SMN1 gene therapy improves disease phenotypes in Smn2B/- spinal muscular atrophy mice (2025)
Journal Article
Sutton, E. R., McCallion, E., Hoolachan, J. M., Çetin, Ö., Pacheco-Torres, P., Rashid, S., Bouhmidi, S., Haynes, K., Churchill, L., Scaife, T., Chaytow, H., Huang, Y.-T., Duguez, S., Schneider, B. L., Gillingwater, T. H., Dimitriadi, M., & Bowerman, M. (in press). Mifepristone alone and in combination with scAAV9-SMN1 gene therapy improves disease phenotypes in Smn2B/- spinal muscular atrophy mice. Scientific Reports.

Population genetics show that aphids (Hemiptera: Aphididae) are limited by summer host-plant distribution at the regional scale (2025)
Journal Article
Garrett, D., Teakle, G., Collier, R., Bell, J., & Morales-Hojas, R. (2025). Population genetics show that aphids (Hemiptera: Aphididae) are limited by summer host-plant distribution at the regional scale. Journal of Insect Science, 25(5), ieaf082. https://doi.org/10.1093/jisesa/ieaf082

Nasonovia ribisnigri (Mosley) is a severe aphid pest of outdoor lettuce, and the combination of sporadic and unpredictable colonization on outdoor lettuce, along with the breakdown of cultivar resistance, has left few effective control methods. The p... Read More about Population genetics show that aphids (Hemiptera: Aphididae) are limited by summer host-plant distribution at the regional scale.

Advances and Challenges in Bioprocess Optimization for the Synthesis of Sugar Nucleotides (2025)
Journal Article
Roberts, T. L., Cosgrove, S. C., & Miller, G. J. (2025). Advances and Challenges in Bioprocess Optimization for the Synthesis of Sugar Nucleotides. ChemBioChem, 202500434. https://doi.org/10.1002/cbic.202500434

Sugar nucleotides represent the cornerstone building blocks for glycan biosynthesis. While methods to access these crucial biomolecules using traditional batch synthetic chemistry and enzymatic approaches have blossomed, uptake using flow‐based synth... Read More about Advances and Challenges in Bioprocess Optimization for the Synthesis of Sugar Nucleotides.

The impact of internal versus external perturbations on close-in exoplanet architectures (2025)
Journal Article
Schoettler, C., & E Owen, J. (n.d.). The impact of internal versus external perturbations on close-in exoplanet architectures [Manuscript submitted for publication]. arXiv. https://www.arxiv.org/abs/2510.03401

Young planetary systems are subjected to different dynamical effects that can influence their orbital structure over time. In systems with more than one planet, other planets can internally influence each other, e.g. via planet-planet scattering. Ext... Read More about The impact of internal versus external perturbations on close-in exoplanet architectures.

Author Correction: Trait mediation explains decadal distributional shifts for a wide range of insect taxa (2025)
Journal Article
Bourhis, Y., Milne, A. E., Shortall, C. R., Beckman, B., Blumgart, D., Edwards, R., Evans, L. C., Foster, C. W., Fox, R., Botham, M. S., Rowland, C., Roberts, S., Speight, M. C. D., Hassall, C., Kunin, W. E., & Bell, J. R. (2025). Author Correction: Trait mediation explains decadal distributional shifts for a wide range of insect taxa. Nature Communications, 16(1), 8737. https://doi.org/10.1038/s41467-025-64720-4

Correction to: Nature Communications https://doi.org/10.1038/s41467-025-63093-y, published online 30 August 2025

In this article there was an error with Figure 5 in which some of the text characters did not get rendered correctly. The original art... Read More about Author Correction: Trait mediation explains decadal distributional shifts for a wide range of insect taxa.

Developing Up-Scale Allogeneic Chondrocyte Therapies Using Juvenile Donor Cartilage (2025)
Journal Article
Hulme, C. H., Perry, J., McCarthy, H. S., Lan, T., Ranasinghe, T., Kiely, N., Freeman, R., Wright, J., & Wright, K. T. (2025). Developing Up-Scale Allogeneic Chondrocyte Therapies Using Juvenile Donor Cartilage. International Journal of Molecular Sciences, 26(19), 9566. https://doi.org/10.3390/ijms26199566

Allogeneic chondrocyte therapies present an attractive alternative to existing autologous therapies for the repair of cartilage defects, enabling the selection of optimal donor cells and streamlined manufacturing processes. This study investigates th... Read More about Developing Up-Scale Allogeneic Chondrocyte Therapies Using Juvenile Donor Cartilage.

A Decade of SBOL Visual: Growing Adoption of a Diagram Standard for Engineering Biology (2025)
Journal Article
Buecherl, L., Buson, F. X., Sørensen, G. H., Vitalis, C., Kubaczka, E., Vidal, G., Bartley, B., Ho, Y.-K., Mısırlı, G., Gorochowski, T. E., Beal, J., Myers, C. J., & Vaidyanathan, P. (2025). A Decade of SBOL Visual: Growing Adoption of a Diagram Standard for Engineering Biology. ACS synthetic biology. https://doi.org/10.1021/acssynbio.5c00417

Standards play a crucial role in ensuring consistency, interoperability, and efficiency of communication across various disciplines. In the field of synthetic biology, the Synthetic Biology Open Language (SBOL) Visual standard was introduced in 2013... Read More about A Decade of SBOL Visual: Growing Adoption of a Diagram Standard for Engineering Biology.

Discovery of SiC and Iron Dust around AGB Stars in the Very Metal-poor Sextans a Dwarf Galaxy with JWST: Implications for Dust Production at High Redshift (2025)
Journal Article
Boyer, M. L., Sloan, G. C., Nanni, A., Tarantino, E., McDonald, I., Goldman, S., Blommaert, J. A. D. L., Dell’Agli, F., Di Criscienzo, M., García-Hernández, D. A., Gehrz, R. D., Groenewegen, M. A. T., Javadi, A., Jones, O. C., Kemper, F., Marengo, M., McQuinn, K. B. W., Oliveira, J. M., Pastorelli, G., Roman-Duval, J., …Whitelock, P. A. (2025). Discovery of SiC and Iron Dust around AGB Stars in the Very Metal-poor Sextans a Dwarf Galaxy with JWST: Implications for Dust Production at High Redshift. The Astrophysical Journal, 991(1), Article 24. https://doi.org/10.3847/1538-4357/adf06a

Low-resolution infrared spectroscopy from JWST confirms the presence of SiC and likely metallic iron dust around asymptotic giant branch (AGB) stars in the Sextans A dwarf galaxy, which has a metallicity ∼1%–7% Z⊙. While metal-poor carbon-rich AGB st... Read More about Discovery of SiC and Iron Dust around AGB Stars in the Very Metal-poor Sextans a Dwarf Galaxy with JWST: Implications for Dust Production at High Redshift.

Autonomous optimisation of biocatalytic reactions: enzymatic synthesis of N -benzyl acetoacetamide in continuous flow (2025)
Journal Article
Takle, M. J., Cosgrove, S. C., & Clayton, A. D. (2025). Autonomous optimisation of biocatalytic reactions: enzymatic synthesis of N -benzyl acetoacetamide in continuous flow. Chemical Science. https://doi.org/10.1039/d5sc04249f

Biocatalysis represents an invaluable tool for developing more sustainable pharmaceutical manufacturing processes. However, the optimisation of these complex transformations remains challenging when using traditional methods. Recent advances in the f... Read More about Autonomous optimisation of biocatalytic reactions: enzymatic synthesis of N -benzyl acetoacetamide in continuous flow.