Aedes aegyptigut transcriptomes respond differently to microbiome transplants from field-caught or laboratory-reared mosquitoes (2023)
Preprint / Working Paper
Hegde, S., Brettell, L. E., Quek, S., Etebari, K., Saldaña, M. A., Asgari, S., Coon, K. L., Heinz, E., & Hughes, G. L. Aedes aegyptigut transcriptomes respond differently to microbiome transplants from field-caught or laboratory-reared mosquitoes

The mosquito microbiome is critical for host development and plays a major role in many aspects of mosquito biology. While the microbiome is commonly dominated by a small number of genera, there is considerable variation in composition among mosquito... Read More about Aedes aegyptigut transcriptomes respond differently to microbiome transplants from field-caught or laboratory-reared mosquitoes.

Inter-species microbiota transplantation recapitulates microbial acquisition and persistence in mosquitoes (2021)
Preprint / Working Paper
Coon, K. L., Hegde, S., & Hughes, G. L. Inter-species microbiota transplantation recapitulates microbial acquisition and persistence in mosquitoes

Background Mosquitoes harbor microbial communities that play important roles in their growth, survival, reproduction, and ability to transmit human pathogens. Microbiome transplantation approaches are often used to study host-microbe interactions and... Read More about Inter-species microbiota transplantation recapitulates microbial acquisition and persistence in mosquitoes.

Microbial interactions in the mosquito gut determine Serratia colonization and blood feeding propensity. (2020)
Preprint / Working Paper
Kozlova, E. V., Hegde, S., Roundy, C. M., Golovko, G., A Saldana, M., Hart, C. E., Anderson, E. R., Hornett, E. A., Khanipov, K., Popov, V. L., Pimenova, M., Zhou, Y., Fovanov, Y., Weaver, S. C., Routh, A. L., Heinz, E., & Hughes, G. L. Microbial interactions in the mosquito gut determine Serratia colonization and blood feeding propensity

How microbe-microbe interactions dictate microbial complexity in the mosquito gut is unclear. Previously we found that Serratia, a gut symbiont that alters vector competence and is being considered for vector control, poorly colonized Aedes aegypti y... Read More about Microbial interactions in the mosquito gut determine Serratia colonization and blood feeding propensity..