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Outputs (2257)

Long-term clinical and cost-effectiveness of collaborative care (versus usual care) for people with mental–physical multimorbidity: cluster-randomised trial (2018)
Journal Article
Chew-Graham, C. (2018). Long-term clinical and cost-effectiveness of collaborative care (versus usual care) for people with mental–physical multimorbidity: cluster-randomised trial. British Journal of Psychiatry, 456-463. https://doi.org/10.1192/bjp.2018.70

Background
Collaborative care can support the treatment of depression in people with long-term conditions, but long-term benefits and costs are unknown.

Aims
To explore the long-term (24-month) effectiveness and cost-effectiveness of collaborati... Read More about Long-term clinical and cost-effectiveness of collaborative care (versus usual care) for people with mental–physical multimorbidity: cluster-randomised trial.

The co-administration of anticancer and pro-apoptotic agents as a novel approach in liver cancer therapy (2018)
Thesis
AL-Shakarchi, W. The co-administration of anticancer and pro-apoptotic agents as a novel approach in liver cancer therapy. (Thesis). Keele University. https://keele-repository.worktribe.com/output/411465

Hepatocellular carcinoma accounts for 85% of primary liver cancer that are usually characterised by defective or ineffective apoptosis which is considered to be the main cause of cancer progression. In this study, Cytochrome-C which is a pro-apoptoti... Read More about The co-administration of anticancer and pro-apoptotic agents as a novel approach in liver cancer therapy.

Digital drug screening to detect falsified, expired andrecalled medicines (2018)
Thesis
Naughton, B. D. Digital drug screening to detect falsified, expired andrecalled medicines. (Thesis). Keele University. https://keele-repository.worktribe.com/output/411443

Falsified medicines are a global health and pharmaceutical sector issue which affect supply chains in low, middle and high-income countries. There are many methods to identify substandard and falsified medicines. However, the European Union has intro... Read More about Digital drug screening to detect falsified, expired andrecalled medicines.

EAHP European Statements Survey 2017, focusing on sections 2 (Selection, Procurement and Distribution), 5 (Patient Safety and Quality Assurance) and 6 (Education and Research). (2018)
Journal Article
(2018). EAHP European Statements Survey 2017, focusing on sections 2 (Selection, Procurement and Distribution), 5 (Patient Safety and Quality Assurance) and 6 (Education and Research). European Journal of Hospital Pharmacy, 237 -244. https://doi.org/10.1136/ejhpharm-2018-001659

Objectives: The 2017 EAHP European Statements Survey focussed on sections 2, 5 and 6 of the European Statements of Hospital Pharmacy. Statistical data on the level of implementation and on the main barriers to implementation of the Statements were co... Read More about EAHP European Statements Survey 2017, focusing on sections 2 (Selection, Procurement and Distribution), 5 (Patient Safety and Quality Assurance) and 6 (Education and Research)..

Effect of Comorbidity On Unplanned Readmissions After Percutaneous Coronary Intervention (From The Nationwide Readmission Database). (2018)
Journal Article
Kwok, C., Mamas, M., Martinez, S., Pancholy, S., Ahmed, W., Al-Shaibi, K., Potts, J., Mohamed, M., Kontopantelis, E., & Curzen, N. (2018). Effect of Comorbidity On Unplanned Readmissions After Percutaneous Coronary Intervention (From The Nationwide Readmission Database). Scientific reports, 11156 -?. https://doi.org/10.1038/s41598-018-29303-y

It is unclear how comorbidity influences rates and causes of unplanned readmissions following percutaneous coronary intervention (PCI). We analyzed patients in the Nationwide Readmission Database who were admitted to hospital between 2010 and 2014. T... Read More about Effect of Comorbidity On Unplanned Readmissions After Percutaneous Coronary Intervention (From The Nationwide Readmission Database)..

Identification of synovial fluid proteins that are associated with early osteoarthritis treatment failure: the search for novel markers leads us back to matrix metalloproteinases (MMPs) (2018)
Presentation / Conference Contribution
Hulme, C., Wilson, E., Fuller, H., Roberts, S., Richardson, J., Gallacher, P., Peffers, M., Shirran, S., Botting, C., & Wright, K. (2018, July). Identification of synovial fluid proteins that are associated with early osteoarthritis treatment failure: the search for novel markers leads us back to matrix metalloproteinases (MMPs). Poster presented at Matrix Biology Europe – July 2018 Meeting Celebrating 50 years of Federation of European Connective Tissue Societies Meetings, Manchester, United Kingdom

Introduction: Autologous chondrocyte implantation (ACI) is a cell therapy used to treat cartilage defects and early osteoarthritis. During initial surgery (Stage I), healthy cartilage is harvested from the joint. Chondrocytes are isolated and culture... Read More about Identification of synovial fluid proteins that are associated with early osteoarthritis treatment failure: the search for novel markers leads us back to matrix metalloproteinases (MMPs).

Discharge Against Medical Advice After Percutaneous Coronary Intervention in the United States (2018)
Journal Article
Al Shaibi, K., Gulati, R., Bell, M., Anderson, V., Potts, J., Rashid, M., Kontopantelis, E., Bagur, R., Mamas, M., & Kwok, C. (2018). Discharge Against Medical Advice After Percutaneous Coronary Intervention in the United States. JACC. Cardiovascular interventions, 1354-1364. https://doi.org/10.1016/j.jcin.2018.03.049

Discharge against medical advice (DAMA) in the context of PCI has not been described in the literature. Among the 2,021,104 patients, the proportion of patients who DAMA was 0.5% (n=10,049). Important predictors of DAMA included diagnosis of acute my... Read More about Discharge Against Medical Advice After Percutaneous Coronary Intervention in the United States.

Relation Between Age and Unplanned Readmissions After Percutaneous Coronary Intervention (Findings From The Nationwide Readmission Database) (2018)
Journal Article
Martinez, S., Rao, S., Gilchrist, I., Kwok, C., Al Ayoubi, F., Myint, P., Mamas, M., Potts, J., Rashid, M., & Kontopantelis, E. (2018). Relation Between Age and Unplanned Readmissions After Percutaneous Coronary Intervention (Findings From The Nationwide Readmission Database). American Journal of Cardiology, 220-228. https://doi.org/10.1016/j.amjcard.2018.03.367

It is unclear how age affects rates and causes of unplanned early readmissions after per cutaneous coronary intervention (PCI). We analyzed patients in the Nationwide Readmission Database in the United States from 2010 to 2014 and examined the impact... Read More about Relation Between Age and Unplanned Readmissions After Percutaneous Coronary Intervention (Findings From The Nationwide Readmission Database).

The association of sex hormone-binding globulin with mortality is mediated by age and testosterone in men with type 2 diabetes. (2018)
Journal Article
Ramachandran, S., Strange, R., Fryer, A., Saad, F., & Hackett, G. (2018). The association of sex hormone-binding globulin with mortality is mediated by age and testosterone in men with type 2 diabetes. Andrology, 6(6), 846-853. https://doi.org/10.1111/andr.12520

BACKGROUND:
Serum sex hormone-binding globulin levels have been associated with mortality in adult men with type 2 diabetes (T2DM).

OBJECTIVES:
To confirm the association of serum sex hormone-binding globulin with mortality and then determine wh... Read More about The association of sex hormone-binding globulin with mortality is mediated by age and testosterone in men with type 2 diabetes..