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Outputs (2257)

Generation and characterisation of tissue-engineered Pseudoislet models for the study of diabetes (2018)
Thesis
Elttayef, A. A. J. Generation and characterisation of tissue-engineered Pseudoislet models for the study of diabetes. (Thesis). Keele University. https://keele-repository.worktribe.com/output/411158

The islets of Langerhans are multicellular aggregates within the pancreas containing beta cells that sense changes in blood glucose level and respond by secreting insulin. The cells within the islets communicate with each other through gap junctions.... Read More about Generation and characterisation of tissue-engineered Pseudoislet models for the study of diabetes.

Implementation and evaluation of a computerised anticoagulation decision support tool for managing atrial fibrillation (2018)
Thesis
Hijazeen, R. Implementation and evaluation of a computerised anticoagulation decision support tool for managing atrial fibrillation. (Thesis). Keele University. https://keele-repository.worktribe.com/output/411452

Background: Anticoagulation therapy for patients with atrial fibrillation (AF) remains a national challenge. A decision support tool (DST) was developed to assist healthcare professionals (HCPs) in the appropriate prescribing of anticoagulants in pat... Read More about Implementation and evaluation of a computerised anticoagulation decision support tool for managing atrial fibrillation.

Clinical simulations using virtual patient avatars for pre-registration pharmacist training: a mixed methods evaluation (2018)
Thesis
Thompson, J. Clinical simulations using virtual patient avatars for pre-registration pharmacist training: a mixed methods evaluation. (Thesis). Keele University. https://keele-repository.worktribe.com/output/411460

Virtual patients (VPs) are routinely used in the training of medicine and nursing professionals but uptake into pharmacy has been slower. The pharmacy pre-registration training year takes place in the workplace and a disparity in the perceptions of s... Read More about Clinical simulations using virtual patient avatars for pre-registration pharmacist training: a mixed methods evaluation.

Validating models of injury risk prediction in football players (2018)
Thesis
Philp, F. D. Validating models of injury risk prediction in football players. (Thesis). Keele University. https://keele-repository.worktribe.com/output/411140

Association football (soccer) is a popular sport and there is a high risk of injury for participants. Within the context of professional clubs, the risk of injury is also associated with the risk of financial costs. Therefore, injury reduction proces... Read More about Validating models of injury risk prediction in football players.

The validation of the Royal Stoke Pharmacy Workforce Calculator – a mixed methods study (2018)
Thesis
Bednall, R. The validation of the Royal Stoke Pharmacy Workforce Calculator – a mixed methods study. (Thesis). Keele University. https://keele-repository.worktribe.com/output/411143

Background
The Royal Stoke Pharmacy Workforce Calculator (RSPWC) was developed to meet a local need of identifying clinical pharmacy staffing levels, not described nationally. This study demonstrates the validity and transferability of the RSPWC an... Read More about The validation of the Royal Stoke Pharmacy Workforce Calculator – a mixed methods study.

Changes in advanced glycation content, structural and mechanical properties of vaginal tissue during pregnancy and in prolapse (2018)
Thesis
Weli, H. K. Changes in advanced glycation content, structural and mechanical properties of vaginal tissue during pregnancy and in prolapse. (Thesis). Keele University. https://keele-repository.worktribe.com/output/411339

Introduction: Pelvic organ prolapse is present in up to 50% of women. It is commoner in older women, often above 50 years of age and associated with hormonal e.g. oestrogen decline, and stiffer vaginal tissue. Pregnancy, on the contrary is a physiolo... Read More about Changes in advanced glycation content, structural and mechanical properties of vaginal tissue during pregnancy and in prolapse.

Silicon in health: A beneficial element in reducing the body burden of aluminium (2018)
Thesis
Jones, K. L. Silicon in health: A beneficial element in reducing the body burden of aluminium. (Thesis). Keele University. https://keele-repository.worktribe.com/output/411347

The essentiality of silicon and the toxicity of aluminium within humans are both topics of much debate; the current conception is that silicon is essential in ameliorating aluminium toxicity, however, the evidence for this remains inconclusive.

T... Read More about Silicon in health: A beneficial element in reducing the body burden of aluminium.

Cell death in the human malaria parasite: exploring autophagy as a drug target and early cellular events following drug perturbation (2018)
Thesis
Ali, I. F. Cell death in the human malaria parasite: exploring autophagy as a drug target and early cellular events following drug perturbation. (Thesis). Keele University. https://keele-repository.worktribe.com/output/411432

The emergence and spread of resistance to antimalarial drugs has highlighted the demand to search for new drugs that target novel pathways in the human malaria parasite Plasmodium falciparum. This thesis explores the potential for targeting of the Pf... Read More about Cell death in the human malaria parasite: exploring autophagy as a drug target and early cellular events following drug perturbation.

Pharmacists in general medical practice: a case study of clinical commissioning groups (2018)
Thesis
Saunders, R. E. Pharmacists in general medical practice: a case study of clinical commissioning groups. (Thesis). Keele University. https://keele-repository.worktribe.com/output/411341

Pharmacists have been identified to address the increasing workload in United Kingdom (UK) general practice. A pilot has been commissioned by National Health Service England (NHSE) to upskill pharmacists for this purpose. Evaluation is underway and e... Read More about Pharmacists in general medical practice: a case study of clinical commissioning groups.