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Outputs (1235)

Sources of prey availability data alter interpretation of outputs from prey choice null networks (2024)
Journal Article
Cuff, J. P., Tercel, M. P., Windsor, F. M., Hawthorne, B. S., Hambäck, P. A., Bell, J. R., …Vaughan, I. P. (2024). Sources of prey availability data alter interpretation of outputs from prey choice null networks. Ecological Entomology, https://doi.org/10.1111/een.13315

Null models provide a valuable baseline against which fundamental ecological hypotheses can be tested and foraging choices that cannot be explained by neutral processes or sampling biases can be highlighted. In this way, null models can advance our u... Read More about Sources of prey availability data alter interpretation of outputs from prey choice null networks.

Heparanase inhibition as a systemic approach to protect the endothelial glycocalyx and prevent microvascular complications in diabetes (2024)
Journal Article
Gamez, M., Elhegni, H. E., Fawaz, S., Ho, K. H., Campbell, N. W., Copland, D. A., …Foster, R. R. (in press). Heparanase inhibition as a systemic approach to protect the endothelial glycocalyx and prevent microvascular complications in diabetes. Cardiovascular Diabetology, 23(1), Article 50. https://doi.org/10.1186/s12933-024-02133-1

Background
Diabetes mellitus is a chronic disease which is detrimental to cardiovascular health, often leading to secondary microvascular complications, with huge global health implications. Therapeutic interventions that can be applied to multiple... Read More about Heparanase inhibition as a systemic approach to protect the endothelial glycocalyx and prevent microvascular complications in diabetes.

Anti-CRISPR Anopheles mosquitoes inhibit gene drive spread under challenging behavioural conditions in large cages (2024)
Journal Article
D’Amato, R., Taxiarchi, C., Galardini, M., Trusso, A., Minuz, R. L., Grilli, S., …Müller, R. (2024). Anti-CRISPR Anopheles mosquitoes inhibit gene drive spread under challenging behavioural conditions in large cages. Nature Communications, 15(1), Article 952. https://doi.org/10.1038/s41467-024-44907-x

CRISPR-based gene drives have the potential to spread within populations and are considered as promising vector control tools. A doublesex-targeting gene drive was able to suppress laboratory Anopheles mosquito populations in small and large cages, a... Read More about Anti-CRISPR Anopheles mosquitoes inhibit gene drive spread under challenging behavioural conditions in large cages.

Ubiquitin ligase and signalling hub MYCBP2 is required for efficient EPHB2 tyrosine kinase receptor function (2024)
Journal Article
Chang, C., Banerjee, S. L., Park, S. S., Zhang, X. L., Cotnoir-White, D., Opperman, K. J., …Kania, A. (2024). Ubiquitin ligase and signalling hub MYCBP2 is required for efficient EPHB2 tyrosine kinase receptor function. eLife, 12, Article RP89176. https://doi.org/10.7554/elife.89176

Eph receptor tyrosine kinases participate in a variety of normal and pathogenic processes during development and throughout adulthood. This versatility is likely facilitated by the ability of Eph receptors to signal through diverse cellular signallin... Read More about Ubiquitin ligase and signalling hub MYCBP2 is required for efficient EPHB2 tyrosine kinase receptor function.

Transgenic expression of cif genes from Wolbachia strain wAlbB recapitulates cytoplasmic incompatibility in Aedes aegypti (2024)
Journal Article
McNamara, C. J., Ant, T. H., Harvey-Samuel, T., White-Cooper, H., Martinez, J., Alphey, L., & Sinkins, S. P. (in press). Transgenic expression of cif genes from Wolbachia strain wAlbB recapitulates cytoplasmic incompatibility in Aedes aegypti. Nature communications, 15(1), Article 869. https://doi.org/10.1038/s41467-024-45238-7

The endosymbiotic bacteria Wolbachia can invade insect populations by modifying host reproduction through cytoplasmic incompatibility (CI), an effect that results in embryonic lethality when Wolbachia-carrying males mate with Wolbachia-free females.... Read More about Transgenic expression of cif genes from Wolbachia strain wAlbB recapitulates cytoplasmic incompatibility in Aedes aegypti.

A multiplexed, confinable CRISPR/Cas9 gene drive can propagate in caged Aedes aegypti populations (2024)
Journal Article
Anderson, M. A. E., Gonzalez, E., Edgington, M. P., Ang, J. X. D., Purusothaman, D.-K., Shackleford, L., …Alphey, L. (in press). A multiplexed, confinable CRISPR/Cas9 gene drive can propagate in caged Aedes aegypti populations. Nature communications, 15(1), Article 729. https://doi.org/10.1038/s41467-024-44956-2

Aedes aegypti is the main vector of several major pathogens including dengue, Zika and chikungunya viruses. Classical mosquito control strategies utilizing insecticides are threatened by rising resistance. This has stimulated interest in new genetic... Read More about A multiplexed, confinable CRISPR/Cas9 gene drive can propagate in caged Aedes aegypti populations.

Two decades of endemic dengue in Bangladesh (2000–2022): trends, seasonality, and impact of temperature and rainfall patterns on transmission dynamics (2024)
Journal Article
Nayeem Hasan, M., Khalil, I., Baker Chowdhury, M. A., Rahman, M., Asaduzzaman, M., Billah, M., …Haider, N. (in press). Two decades of endemic dengue in Bangladesh (2000–2022): trends, seasonality, and impact of temperature and rainfall patterns on transmission dynamics. Journal of Medical Entomology, 61(2), 345-353. https://doi.org/10.60692/gc5zx-3tc77

The objectives of this study were to compare dengue virus (DENV) cases, deaths, case-fatality ratio [CFR], and meteorological parameters between the first and the recent decades of this century (2000-2010 vs. 2011-2022) and to describe the trends, se... Read More about Two decades of endemic dengue in Bangladesh (2000–2022): trends, seasonality, and impact of temperature and rainfall patterns on transmission dynamics.

Two decades of endemic dengue in Bangladesh (2000–2022): trends, seasonality, and impact of temperature and rainfall patterns on transmission dynamics (2024)
Journal Article
Nayeem Hasan, M., Khalil, I., Baker Chowdhury, M. A., Rahman, M., Asaduzzaman, M., Billah, M., …Haider, N. (in press). Two decades of endemic dengue in Bangladesh (2000–2022): trends, seasonality, and impact of temperature and rainfall patterns on transmission dynamics. GreSIS - Greater South Information System, https://doi.org/10.60692/x6t6v-mbt18

The objectives of this study were to compare dengue virus (DENV) cases, deaths, case-fatality ratio [CFR], and meteorological parameters between the first and the recent decades of this century (2000-2010 vs. 2011-2022) and to describe the trends, se... Read More about Two decades of endemic dengue in Bangladesh (2000–2022): trends, seasonality, and impact of temperature and rainfall patterns on transmission dynamics.

Two decades of endemic dengue in Bangladesh (2000–2022): trends, seasonality, and impact of temperature and rainfall patterns on transmission dynamics (2024)
Journal Article
Hasan, M. N., Khalil, I., Chowdhury, M. A. B., Rahman, M., Asaduzzaman, M., Billah, M., …Haider, N. (in press). Two decades of endemic dengue in Bangladesh (2000–2022): trends, seasonality, and impact of temperature and rainfall patterns on transmission dynamics. Journal of Medical Entomology, Article tjae001. https://doi.org/10.1093/jme/tjae001

The objectives of this study were to compare dengue virus (DENV) cases, deaths, case-fatality ratio [CFR], and meteorological parameters between the first and the recent decades of this century (2000–2010 vs. 2011–2022) and to describe the trends, se... Read More about Two decades of endemic dengue in Bangladesh (2000–2022): trends, seasonality, and impact of temperature and rainfall patterns on transmission dynamics.