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Outputs (22)

One-session treatment compared with multisession CBT in children aged 7–16 years with specific phobias: the ASPECT non-inferiority RCT (2022)
Journal Article

BACKGROUND: Up to 10% of children and young people have a specific phobia that can significantly affect their mental health, development and daily functioning. Cognitive-behavioural therapy-based interventions remain the dominant treatment, but limit... Read More about One-session treatment compared with multisession CBT in children aged 7–16 years with specific phobias: the ASPECT non-inferiority RCT.

The alleviating specific phobias in children trial: Challenges and solutions to implementing a randomized controlled trial in clinical services (2022)
Journal Article

In 2015, The Alleviating Specific Phobias Experienced by Children Trial (ASPECT) was commissioned by the National Institute for Health and Care Research (NIHR) to compare the clinical and cost-effectiveness of multi-session Cognitive Behavioral Thera... Read More about The alleviating specific phobias in children trial: Challenges and solutions to implementing a randomized controlled trial in clinical services.

One-session treatment for specific phobias: Barriers, facilitators and acceptability as perceived by children & young people, parents, and clinicians (2022)
Journal Article

Between 2015 and 2020 the Alleviating Specific Phobias Experienced by Children Trial (ASPECT) was conducted in the UK to examine the non-inferiority of One-Session Treatment in comparison to Cognitive Behavioural Therapy based interventions for child... Read More about One-session treatment for specific phobias: Barriers, facilitators and acceptability as perceived by children & young people, parents, and clinicians.

Cost and effectiveness of one session treatment (OST) for children and young people with specific phobias compared to multi-session cognitive behavioural therapy (CBT): results from a randomised controlled trial (2022)
Journal Article

Abstract Background In the UK, around 93,000 (0.8%) children and young people (CYP) are experiencing specific phobias that have a substantial impact on daily life. The current gold-standard treatment—multi-session cognitive behavioural therapy (CBT)... Read More about Cost and effectiveness of one session treatment (OST) for children and young people with specific phobias compared to multi-session cognitive behavioural therapy (CBT): results from a randomised controlled trial.

One session treatment (OST) is equivalent to multi-session cognitive behavioral therapy (CBT) in children with specific phobias (ASPECT): results from a national non-inferiority randomized controlled trial (2022)
Journal Article

Background5%–10% children and young people (CYP) experience specific phobias that impact daily functioning. Cognitive Behaviour Therapy (CBT) is recommended but has limitations. One Session Treatment (OST), a briefer alternative incorporating CBT pri... Read More about One session treatment (OST) is equivalent to multi-session cognitive behavioral therapy (CBT) in children with specific phobias (ASPECT): results from a national non-inferiority randomized controlled trial.

Improving Sleep Quality Leads to Better Mental Health: A Meta-Analysis of Randomised Controlled Trials (2021)
Journal Article

Summary The extent to which sleep is causally related to mental health is unclear. One way to test the causal link is to evaluate the extent to which interventions that improve sleep quality also improve mental health. We conducted a meta-analysis of... Read More about Improving Sleep Quality Leads to Better Mental Health: A Meta-Analysis of Randomised Controlled Trials.

Improving Sleep Quality Leads to Better Mental Health: A Meta-Analysis of Randomised Controlled Trials (2021)
Journal Article

The extent to which sleep is causally related to mental health is unclear. One way to test the causal link is to evaluate the extent to which interventions that improve sleep quality also improve mental health. We conducted a meta-analysis of randomi... Read More about Improving Sleep Quality Leads to Better Mental Health: A Meta-Analysis of Randomised Controlled Trials.

Perceptions of sleep in Inflammatory Bowel Disease and the acceptability of sleep interventions in routine care: A qualitative study (2021)
Journal Article

There have been increased calls to manage poor sleep in Inflammatory Bowel Disease (IBD) care. However, it’s unclear how people with IBD perceive their sleep to fit within their experience of IBD and whether interventions to improve sleep are accepta... Read More about Perceptions of sleep in Inflammatory Bowel Disease and the acceptability of sleep interventions in routine care: A qualitative study.

Prehospital continuous positive airway pressure for acute respiratory failure: the ACUTE feasibility RCT (2021)
Journal Article

BACKGROUND: Acute respiratory failure is a life-threatening emergency. Standard prehospital management involves controlled oxygen therapy. Continuous positive airway pressure is a potentially beneficial alternative treatment; however, it is uncertain... Read More about Prehospital continuous positive airway pressure for acute respiratory failure: the ACUTE feasibility RCT.

Do specific types of sleep disturbances represent risk factors for poorer health-related quality of life in inflammatory bowel disease? A longitudinal cohort study. (2021)
Journal Article

OBJECTIVES: Poor global sleep quality is commonly reported in people with inflammatory bowel disease (IBD) and is linked to poorer health-related quality of life (HRQoL). However, understanding is currently limited by a lack of: (1) longitudinal rese... Read More about Do specific types of sleep disturbances represent risk factors for poorer health-related quality of life in inflammatory bowel disease? A longitudinal cohort study..

Feasibility study for supporting medication adherence for adults with cystic fibrosis: mixed-methods process evaluation. (2020)
Journal Article

OBJECTIVES: To undertake a process evaluation of an adherence support intervention for people with cystic fibrosis (PWCF), to assess its feasibility and acceptability. SETTING: Two UK cystic fibrosis (CF) units. PARTICIPANTS: Fourteen adult PWCF; thr... Read More about Feasibility study for supporting medication adherence for adults with cystic fibrosis: mixed-methods process evaluation..

Mechanisms of Action of a Web-Based Intervention With Health Professional Support to Increase Adherence to Nebulizer Treatments in Adults With Cystic Fibrosis: Qualitative Interview Study. (2020)
Journal Article

BACKGROUND: Adherence to nebulizer treatments in adults with cystic fibrosis (CF) is often low. A new complex intervention to help adults with CF increase their adherence to nebulizer treatments was tested in a pilot randomized controlled trial (RCT)... Read More about Mechanisms of Action of a Web-Based Intervention With Health Professional Support to Increase Adherence to Nebulizer Treatments in Adults With Cystic Fibrosis: Qualitative Interview Study..

The Effect of an Online Self-Help Cognitive Behavioural Intervention for Insomnia on Negative Affect and Paranoia: A Randomised Controlled Trial (2020)
Journal Article

Background: Sleep and mental health go hand-in-hand, with problems sleeping being associated with a variety of mental health difficulties. Recently, insomnia has been linked with the experience of paranoia, a relationship that is likely to be mediate... Read More about The Effect of an Online Self-Help Cognitive Behavioural Intervention for Insomnia on Negative Affect and Paranoia: A Randomised Controlled Trial.

Is a definitive trial of prehospital continuous positive airway pressure versus standard oxygen therapy for acute respiratory failure indicated? The ACUTE pilot randomised controlled trial. (2020)
Journal Article

OBJECTIVES: To determine the feasibility of a large-scale definitive multicentre trial of prehospital continuous positive airway pressure (CPAP) in acute respiratory failure. DESIGN: A single-centre, open-label, individual patient randomised, con... Read More about Is a definitive trial of prehospital continuous positive airway pressure versus standard oxygen therapy for acute respiratory failure indicated? The ACUTE pilot randomised controlled trial..

A comparative study of the nature and magnitude of problems sleeping in inflammatory bowel disease (IBD) compared to healthy controls (2020)
Journal Article

Inflammatory Bowel Disease (IBD) is commonly associated with poor global sleep quality, and has been posited as a modifiable determinant of IBD related outcomes. However, there is little evidence on the specific types of problems sleeping (e.g., slee... Read More about A comparative study of the nature and magnitude of problems sleeping in inflammatory bowel disease (IBD) compared to healthy controls.

Clinical and cost-effectiveness of one-session treatment (OST) versus multisession cognitive–behavioural therapy (CBT) for specific phobias in children: protocol for a non-inferiority randomised controlled trial (2018)
Journal Article

Specific phobias (intense, enduring fears of an object or situation that lead to avoidance and severe distress) are highly prevalent among children and young people. Cognitive–behavioural therapy (CBT) is a wellestablished, effective interven... Read More about Clinical and cost-effectiveness of one-session treatment (OST) versus multisession cognitive–behavioural therapy (CBT) for specific phobias in children: protocol for a non-inferiority randomised controlled trial.

A structural equation model of the relationship between insomnia, negative affect, and paranoid thinking (2017)
Journal Article

A growing body of evidence points to relationships between insomnia, negative affect, and paranoid thinking. However, studies are needed to examine (i) whether negative affect mediates the relation between insomnia and paranoid thinking, (ii) whether... Read More about A structural equation model of the relationship between insomnia, negative affect, and paranoid thinking.