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Ivonne Solis-Trapala's Outputs (45)

Centre-level fluid management practices in the BISTRO trial and their lack of association with participant fluid status and blood pressure in non-anuric haemodialysis patients (2024)
Journal Article
Johal, N., Sharma, R., Belcher, J., Coyle, D., Lindley, E. J., Keane, D., …Davies, S. J. (2024). Centre-level fluid management practices in the BISTRO trial and their lack of association with participant fluid status and blood pressure in non-anuric haemodialysis patients. BMC Nephrology, 25(1), Article 398. https://doi.org/10.1186/s12882-024-03837-y

Introduction: Fluid assessment and management is a key aspect of good dialysis care and is affected by patient-level characteristics and potentially centre-level practices. In this secondary analysis of the BISTRO trial we wished to establish whether... Read More about Centre-level fluid management practices in the BISTRO trial and their lack of association with participant fluid status and blood pressure in non-anuric haemodialysis patients.

Impact of the Preservation of Residual Kidney Function on Hemodialysis Survival: Results from the BISTRO Trial (2024)
Journal Article
Belcher, J., Coyle, D., Lindley, E. J., Keane, D., Caskey, F. J., Dasgupta, I., …Davies, S. J. (2024). Impact of the Preservation of Residual Kidney Function on Hemodialysis Survival: Results from the BISTRO Trial. Kidney360, https://doi.org/10.34067/kid.0000000596

Preservation of residual kidney function (RKF) in dialysis patients has been associated with improved survival. RKF in the BISTRO trial was relatively well preserved and here we describe its association with survival during the trial and extended fol... Read More about Impact of the Preservation of Residual Kidney Function on Hemodialysis Survival: Results from the BISTRO Trial.

Cost-effectiveness of bioimpedance-guided fluid management in patients undergoing haemodialysis: the BISTRO RCT (2024)
Journal Article
Zanganeh, M., Belcher, J., Fotheringham, J., Coyle, D., Lindley, E. J., Keane, D. F., …Andronis, L. (2024). Cost-effectiveness of bioimpedance-guided fluid management in patients undergoing haemodialysis: the BISTRO RCT. Health Technology Assessment, 1-45. https://doi.org/10.3310/jypr4287

Background
The BioImpedance Spectroscopy to maintain Renal Output randomised controlled trial investigated the effect of bioimpedance spectroscopy added to a standardised fluid management protocol on the risk of anuria and preservation of residual k... Read More about Cost-effectiveness of bioimpedance-guided fluid management in patients undergoing haemodialysis: the BISTRO RCT.

Centre variation in home dialysis uptake: A survey of kidney centre practice in relation to home dialysis organisation and delivery in England (2024)
Journal Article
Damery, S., Lambie, M., Williams, I., Coyle, D., Fotheringham, J., Solis-Trapala, I., …Davies, S. J. (2024). Centre variation in home dialysis uptake: A survey of kidney centre practice in relation to home dialysis organisation and delivery in England. Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis, https://doi.org/10.1177/08968608241232200

Background:
Disparities in home dialysis uptake across England suggest inequity and unexplained variation in access. We surveyed staff at all English kidney centres to identify patterns in service organisation/delivery and explore correlations with... Read More about Centre variation in home dialysis uptake: A survey of kidney centre practice in relation to home dialysis organisation and delivery in England.

Using healthcare systems data for outcomes in clinical trials: issues to consider at the design stage (2024)
Journal Article
Toader, A.-M., Campbell, M. K., Quint, J. K., Robling, M., ydes, M. R., Thorn, J., …Williamson, P. (2024). Using healthcare systems data for outcomes in clinical trials: issues to consider at the design stage. Trials, 25(1), https://doi.org/10.1186/s13063-024-07926-z

Background
Healthcare system data (HSD) are increasingly used in clinical trials, augmenting or replacing traditional methods of collecting outcome data. This study, PRIMORANT, set out to identify, in the UK context, issues to be considered before t... Read More about Using healthcare systems data for outcomes in clinical trials: issues to consider at the design stage.

How do clinicians prescribe bridging glucocorticoids in people starting or escalating disease-modifying anti-rheumatic drugs for rheumatoid arthritis: a service evaluation survey (2023)
Journal Article
Prior, J. A., Roddy, E., Solis-Trapala, I., Cornwall, N., Jinks, C., Abhishek, A., …Hider, S. (in press). How do clinicians prescribe bridging glucocorticoids in people starting or escalating disease-modifying anti-rheumatic drugs for rheumatoid arthritis: a service evaluation survey. Rheumatology Advances in Practice, 7(3), Article rkad102. https://doi.org/10.1093/rap/rkad102

Estimating the association between systemic Interleukin-6 and mortality in the dialysis population. Re-analysis of the global fluid study, systematic review and meta-analysis (2023)
Journal Article
Istanbuly, O., Belcher, J., Tabinor, M., Solis-Trapala, I., Lambie, M., & Davies, S. J. (in press). Estimating the association between systemic Interleukin-6 and mortality in the dialysis population. Re-analysis of the global fluid study, systematic review and meta-analysis. BMC Nephrology, 24(1), Article 312. https://doi.org/10.1186/s12882-023-03370-4

Background: Systemic inflammation, measured as circulating Interleukin-6 (IL-6) levels, is associated with cardiovascular and all-cause mortality in chronic kidney disease. However, this has not been convincingly demonstrated in a systematic review o... Read More about Estimating the association between systemic Interleukin-6 and mortality in the dialysis population. Re-analysis of the global fluid study, systematic review and meta-analysis.

Catheter Event Rates in Medical Compared to Surgical Peritoneal Dialysis Catheter Insertion (2023)
Journal Article
Fotheringham, J., Solis-Trapala, I., Briggs, V., Lambie, M., McCullough, K., Dunn, L., …Wilkie, M. (2023). Catheter Event Rates in Medical Compared to Surgical Peritoneal Dialysis Catheter Insertion. Kidney International Reports, 8(12), 2635-2645. https://doi.org/10.1016/j.ekir.2023.09.015

How patient, center, and insertion technique factors interact needs to be understood when designing peritoneal dialysis (PD) catheter insertion pathways. We undertook a prospective cohort study in 44 UK centers enrolling participants planned for firs... Read More about Catheter Event Rates in Medical Compared to Surgical Peritoneal Dialysis Catheter Insertion.

Patients’ experiences of a suppoRted self-manAGeMent pAThway In breast Cancer (PRAGMATIC): quality of life and service use results (2023)
Journal Article
Jenkins, V., Matthews, L., Solis-Trapala, I., Gage, H., May, S., Williams, P., …Teoh, M. (2023). Patients’ experiences of a suppoRted self-manAGeMent pAThway In breast Cancer (PRAGMATIC): quality of life and service use results. Supportive Care in Cancer, 31(10), Article 570. https://doi.org/10.1007/s00520-023-08002-z

Purpose
To describe trends and explore factors associated with quality of life (QoL) and psychological morbidity and assess breast cancer (BC) health service use over a 12-month period for patients joining the supported self-management (SSM)/patient... Read More about Patients’ experiences of a suppoRted self-manAGeMent pAThway In breast Cancer (PRAGMATIC): quality of life and service use results.

Bio-impedance spectroscopy added to a fluid management protocol does not improve preservation of residual kidney function in incident hemodialysis patients in a randomized controlled trial (2023)
Journal Article
Davies, S. J., Coyle, D., Lindley, E. J., Keane, D., Belcher, J., Caskey, F. J., …Sim, J. (2023). Bio-impedance spectroscopy added to a fluid management protocol does not improve preservation of residual kidney function in incident hemodialysis patients in a randomized controlled trial. Kidney International, 104(3), 587-598. https://doi.org/10.1016/j.kint.2023.05.016

Avoiding excessive dialysis-associated volume depletion may help preserve residual kidney function (RKF). To establish whether knowledge of the estimated normally hydrated weight from bioimpedance measurements (BI-NHW) when setting the post-hemodialy... Read More about Bio-impedance spectroscopy added to a fluid management protocol does not improve preservation of residual kidney function in incident hemodialysis patients in a randomized controlled trial.

Are childhood factors predictive of adult health literacy? A longitudinal birth cohort analysis (2023)
Journal Article
Solis-Trapala, I., Campbell, P., Lacey, R., Rowlands, G., Dunn, K., & Protheroe, J. (2023). Are childhood factors predictive of adult health literacy? A longitudinal birth cohort analysis. SSM - Population Health, 13, Article 101426. https://doi.org/10.1016/j.ssmph.2023.101426

Health literacy (HL), defined as the ability of an individual to understand and appraise health information to make informed decisions on their health, helps maintain and improve one's health and thus reduce the use of healthcare services. There is a... Read More about Are childhood factors predictive of adult health literacy? A longitudinal birth cohort analysis.

Protocol for CLASSIC PBB: comparison of lower airway sampling strategies in children with protracted bacterial bronchitis (2022)
Journal Article
Gilchrist, F., Aspey, M., Bowler, R., Brodlie, M., Desai, S., Harris, C., …Carroll, W. D. (2022). Protocol for CLASSIC PBB: comparison of lower airway sampling strategies in children with protracted bacterial bronchitis. BMJ Paediatrics Open, e001722 - e001722. https://doi.org/10.1136/bmjpo-2022-001722

Background Protracted bacterial bronchitis (PBB) is an endobronchial infection and a the most common cause of chronic wet cough in young children. It is treated with antibiotics, which can only be targeted if the causative organism is known. As most... Read More about Protocol for CLASSIC PBB: comparison of lower airway sampling strategies in children with protracted bacterial bronchitis.

Talking about Risk, UncertaintieS of Testing IN Genetics (TRUSTING): development and evaluation of an educational programme for healthcare professionals about BRCA1 & BRCA2 testing (2022)
Journal Article
Fallowfield, L., Solis-Trapala, Solis-Trapala, I., Starkings, R., May, S., Matthews, L., …Jenkins, V. (2022). Talking about Risk, UncertaintieS of Testing IN Genetics (TRUSTING): development and evaluation of an educational programme for healthcare professionals about BRCA1 & BRCA2 testing. British Journal of Cancer, 127, 1116-1122. https://doi.org/10.1038/s41416-022-01871-x

Background Mainstreaming of germline testing demands that all healthcare professionals have good communication skills, but few have genetic testing and counselling experience. We developed and evaluated educational workshops-Talking about Risk & Unce... Read More about Talking about Risk, UncertaintieS of Testing IN Genetics (TRUSTING): development and evaluation of an educational programme for healthcare professionals about BRCA1 & BRCA2 testing.

Intervening to eliminate the centre-effect variation in home dialysis use: protocol for Inter-CEPt—a sequential mixed-methods study designing an intervention bundle (2022)
Journal Article
Tshimologo, M., Allen, K., Coyle, D., Damery, S., Dikomitis, L., Fotheringham, J., …Davies, S. (2022). Intervening to eliminate the centre-effect variation in home dialysis use: protocol for Inter-CEPt—a sequential mixed-methods study designing an intervention bundle. BMJ Open, e060922 - ?. https://doi.org/10.1136/bmjopen-2022-060922

INTRODUCTION: Use of home dialysis by centres in the UK varies considerably and is decreasing despite attempts to encourage greater use. Knowing what drives this unwarranted variation requires in-depth understanding of centre cultural and organisatio... Read More about Intervening to eliminate the centre-effect variation in home dialysis use: protocol for Inter-CEPt—a sequential mixed-methods study designing an intervention bundle.

Impact of the implementation of an assisted peritoneal dialysis service on peritoneal dialysis initiation (2020)
Journal Article
Boyer, A., Solis-Trapala, I., Tabinor, M., Lambie, M., & Davies, S. (2020). Impact of the implementation of an assisted peritoneal dialysis service on peritoneal dialysis initiation. Nephrology Dialysis Transplantation, 35(9), 1595-1601. https://doi.org/10.1093/ndt/gfz287

<jats:title>Abstract</jats:title> <jats:sec> <jats:title>Background</jats:title> <jats:p>There is limited information available on the impact that provision of an assisted peritoneal dialysis (PD) service has on the initiation of PD. The aim of this... Read More about Impact of the implementation of an assisted peritoneal dialysis service on peritoneal dialysis initiation.

Talking About Risk in the Context of GEnomic Tests (TARGET): Development and evaluation of an educational program for clinicians (2019)
Journal Article
Fallowfield, L., Solis-Trapala, I., Starkings, R., Catt, S., May, S., & Jenkins, V. (2019). Talking About Risk in the Context of GEnomic Tests (TARGET): Development and evaluation of an educational program for clinicians. Breast Cancer Research and Treatment, 177, 641-649. https://doi.org/10.1007/s10549-019-05316-7

Purpose: Gene expression profiling (GEP) test scores calculate risks of recurrence and likely benefit of adjuvant chemotherapy in ER positive, HER2 negative, early stage breast cancer. As health literacy and numeracy skills in the general population... Read More about Talking About Risk in the Context of GEnomic Tests (TARGET): Development and evaluation of an educational program for clinicians.

Estimating risk of encapsulating peritoneal sclerosis accounting for the competing risk of death (2019)
Journal Article
Lambie, M., Teece, L., Johnson, D. W., Petrie, M., Mactier, R., Solis-Trapala, I., …Davies, S. J. (2019). Estimating risk of encapsulating peritoneal sclerosis accounting for the competing risk of death. Nephrology Dialysis Transplantation, 1585-1591. https://doi.org/10.1093/ndt/gfz034

Background
Risk of Encapsulating Peritoneal Sclerosis (EPS) is strongly associated with the duration of peritoneal dialysis (PD), such that patients who have been on PD for some time may consider elective transfer to haemodialysis to mitigate risk o... Read More about Estimating risk of encapsulating peritoneal sclerosis accounting for the competing risk of death.

Treatment Experiences, Information Needs, Pain and Quality of Life in Men with Metastatic Castrate-resistant Prostate Cancer: Results from the EXTREQOL Study (2018)
Journal Article
Jenkins, V., Solis-Trapala, I., Payne, H., Mason, M., Fallowfield, L., May, S., …Catt, S. (2019). Treatment Experiences, Information Needs, Pain and Quality of Life in Men with Metastatic Castrate-resistant Prostate Cancer: Results from the EXTREQOL Study. Clinical Oncology, 31(2), 99-107. https://doi.org/10.1016/j.clon.2018.11.001

Aims
Delaying progression, ameliorating symptoms and maintaining quality of life (QoL) are primary aims of treatment for metastatic castrate-resistant prostate cancer (mCRPC). Real-world rather than clinical trial data about symptoms and side-effect... Read More about Treatment Experiences, Information Needs, Pain and Quality of Life in Men with Metastatic Castrate-resistant Prostate Cancer: Results from the EXTREQOL Study.

The frequency of testing for glycated haemoglobin, HbA1c, is linked to the probability of achieving target levels in patients with suboptimally controlled diabetes mellitus. (2018)
Journal Article
Duff, C. J., Solis-Trapala, I., Driskell, O. J., Holland, D., Wright, H., Waldron, J. L., …Fryer, A. A. (2018). The frequency of testing for glycated haemoglobin, HbA1c, is linked to the probability of achieving target levels in patients with suboptimally controlled diabetes mellitus. Clinical Chemistry and Laboratory Medicine, https://doi.org/10.1515/cclm-2018-0503

Introduction:
We previously showed, in patients with diabetes, that >50% of monitoring tests for glycated hemoglobin (HbA1c) are outside recommended intervals and that this is linked to diabetes control. Here, we examined the impact of tests/year on... Read More about The frequency of testing for glycated haemoglobin, HbA1c, is linked to the probability of achieving target levels in patients with suboptimally controlled diabetes mellitus..