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Dual stressors of infection and warming can destabilize host microbiomes (2024)
Journal Article
Li, J., Gao, Y., Stevens, E., & King, K. (2024). Dual stressors of infection and warming can destabilize host microbiomes. Philosophical Transactions B: Biological Sciences, 379(1901), https://doi.org/10.1098/rstb.2023.0069

Climate change is causing extreme heating events and intensifying infectious disease outbreaks. Animals harbour microbial communities, which are vital for their survival and fitness under stressful conditions. Understanding how microbiome structures... Read More about Dual stressors of infection and warming can destabilize host microbiomes.

Within- and between-host dynamics of producer and non-producer pathogens (2023)
Journal Article
Pike, V. L., Stevens, E. J., Griffin, A. S., & King, K. C. (2023). Within- and between-host dynamics of producer and non-producer pathogens. Parasitology, https://doi.org/10.1017/S0031182023000586

For infections to be maintained in a population, pathogens must compete to colonize hosts and transmit between them. We use an experimental approach to investigate within-and-between host dynamics using the pathogen Pseudomonas aeruginosa and the ani... Read More about Within- and between-host dynamics of producer and non-producer pathogens.

The evolution of colistin resistance increases bacterial resistance to host antimicrobial peptides and virulence (2023)
Journal Article
Jangir, P., Ogunlana, L., Szili, P., Czikkely, M., P Shaw, L., Stevens, E. J., …R MacLean, C. (2023). The evolution of colistin resistance increases bacterial resistance to host antimicrobial peptides and virulence. eLife, 12, 1-22. https://doi.org/10.7554/elife.84395

Antimicrobial peptides (AMPs) offer a promising solution to the antibiotic resistance crisis. However, an unresolved serious concern is that the evolution of resistance to therapeutic AMPs may generate cross-resistance to host AMPs, compromising a co... Read More about The evolution of colistin resistance increases bacterial resistance to host antimicrobial peptides and virulence.