The evolution of a stereoselective synthesis of the C1–C16 fragment of bryostatins (2016)
Journal Article
Ball, M., Baron, A., Bradshaw, B., Dumeunier, R., O'Brien, M., & Thomas, E. J. The evolution of a stereoselective synthesis of the C1–C16 fragment of bryostatins. Organic and Biomolecular Chemistry, 14(40), 9650-9681. https://doi.org/10.1039/c6ob01804a

The development of a synthesis of the C1–C16 fragment of bryostatins in which the key step is a stereoselective oxy-Michael reaction used to assemble the cis-2,6-disubstituted tetrahydropyran with the exocyclic alkene already installed, is described.... Read More about The evolution of a stereoselective synthesis of the C1–C16 fragment of bryostatins.