Label-Free In Situ Chemical Characterization of Amyloid Plaques in Human Brain Tissues (2024)
Journal Article
Everett, J., Brooks, J., Tjendana Tjhin, V., Lermyte, F., Hands-Portman, I., Plascencia-Villa, G., …Telling, N. D. (2024). Label-Free In Situ Chemical Characterization of Amyloid Plaques in Human Brain Tissues. ACS chemical neuroscience, 15(7), 1469–1483. https://doi.org/10.1021/acschemneuro.3c00756

The accumulation of amyloid plaques and increased brain redox burdens are neuropathological hallmarks of Alzheimer’s disease. Altered metabolism of essential biometals is another feature of Alzheimer’s, with amyloid plaques representing sites of dist... Read More about Label-Free In Situ Chemical Characterization of Amyloid Plaques in Human Brain Tissues.