Skip to main content

Research Repository

Advanced Search

Outputs (2252)

Metamizole in the Management of Musculoskeletal Disorders: Current Concept Review (2024)
Journal Article
Jeyaraman, N., Migliorini, F., Murugan, S., Ramasubramanian, S., Balaji, S., Maffulli, N., & Jeyaraman, M. (in press). Metamizole in the Management of Musculoskeletal Disorders: Current Concept Review. Journal of Clinical Medicine, 13(16), Article 4794. https://doi.org/10.3390/jcm13164794

Metamizole, or dipyrone, has been used for decades as a non-narcotic analgesic, providing pain relief from musculoskeletal disorders and antipyretic and antispasmolytic properties. Despite being in use since the 1920s, its mechanism of action still n... Read More about Metamizole in the Management of Musculoskeletal Disorders: Current Concept Review.

Testosterone undecanoate is associated with improved ageing male symptoms score in men with type 2 diabetes and adult-onset testosterone deficiency: re-analyzed results from a randomised controlled trial (2024)
Journal Article
Ramachandran, P., Zitzmann, M., König, C. S., Mulhern, J., Ramachandran, S., & Hackett, G. (in press). Testosterone undecanoate is associated with improved ageing male symptoms score in men with type 2 diabetes and adult-onset testosterone deficiency: re-analyzed results from a randomised controlled trial. Exploration of Endocrine and Metabolic Diseases, 2024(1), 177-190. https://doi.org/10.37349/eemd.2024.00015

Aim: To evaluate changes in quality of life via the ageing male symptom scale (AMSS) and somatic, psychological, and sexual sub-scales following testosterone undecanoate (TU) or placebo (P) treatment in men with type 2 diabetes mellitus (T2DM) and ad... Read More about Testosterone undecanoate is associated with improved ageing male symptoms score in men with type 2 diabetes and adult-onset testosterone deficiency: re-analyzed results from a randomised controlled trial.

Antithrombotic prophylaxis following total knee arthroplasty: a level I Bayesian network meta-analysis. (2024)
Journal Article
Migliorini, F., Maffulli, N., Velaj, E., Bell, A., Kämmer, D., Eschweiler, J., & Hofmann, U. K. (in press). Antithrombotic prophylaxis following total knee arthroplasty: a level I Bayesian network meta-analysis. European Journal of Orthopaedic Surgery and Traumatology, https://doi.org/10.1007/s00590-024-04071-w

Venous thromboembolism (VTE) is a major concern following total knee arthroplasty (TKA). The optimal pharmacological prophylaxis remains, however, controversial. The present investigation compared several non-vitamin K antagonist oral anticoagulants... Read More about Antithrombotic prophylaxis following total knee arthroplasty: a level I Bayesian network meta-analysis..

Brain Punch: K-1 Fights Affect Brain Wave Activity in Professional Kickboxers. (2024)
Journal Article
Rydzik, Ł., Kopańska, M., Wąsacz, W., Ouergui, I., Obmiński, Z., Pałka, T., Ambroży, T., Malliaropoulos, N., Maffulli, N., Lota, K. S., Jaszczur-Nowicki, J., Król, P., Czarny, W., & Szczygielski, J. (in press). Brain Punch: K-1 Fights Affect Brain Wave Activity in Professional Kickboxers. Sports Medicine, https://doi.org/10.1007/s40279-024-02082-5

Kickboxing is a popular striking combat sport, and K-1 is a type of kickboxing. Direct head blows can cause significant long-term injury and affect brain wave activity. We aim to compare the changes in brain wave activities of fighters during a K-1 k... Read More about Brain Punch: K-1 Fights Affect Brain Wave Activity in Professional Kickboxers..

Modelling take-off moment arms in an ornithocheiraean pterosaur (2024)
Journal Article
Griffin, B. W., Martin-Silverstone, E., Pêgas, R. V., Meilak, E. A., Costa, F. R., Palmer, C., & Rayfield, E. J. (in press). Modelling take-off moment arms in an ornithocheiraean pterosaur. PeerJ, 12, Article e17678. https://doi.org/10.7717/peerj.17678

Take-off is a vital part of powered flight which likely constrains the size of birds, yet extinct pterosaurs are known to have reached far larger sizes. Three different hypothesised take-off motions (bipedal burst launching, bipedal countermotion lau... Read More about Modelling take-off moment arms in an ornithocheiraean pterosaur.

Exploring non-viral methods for the delivery of CRISPR-Cas ribonucleoprotein to hematopoietic stem cells (2024)
Journal Article
Molaei, Z., Jabbarpour, Z., Omidkhoda, A., & Ahmadbeigi, N. (in press). Exploring non-viral methods for the delivery of CRISPR-Cas ribonucleoprotein to hematopoietic stem cells. Stem Cell Research and Therapy, 15(1), Article 233. https://doi.org/10.1186/s13287-024-03848-4

Gene manipulation of hematopoietic stem cells (HSCs) using the CRISPR/Cas system as a potent genome editing tool holds immense promise for addressing hematologic disorders. An essential hurdle in advancing this treatment lies in effectively deliverin... Read More about Exploring non-viral methods for the delivery of CRISPR-Cas ribonucleoprotein to hematopoietic stem cells.

A phosphate glass reinforced composite acrylamide gradient scaffold for osteochondral interface regeneration. (2024)
Journal Article
Younus, Z. M., Ahmed, I., Roach, P., & Forsyth, N. R. (in press). A phosphate glass reinforced composite acrylamide gradient scaffold for osteochondral interface regeneration. Biomaterials and Biosystems, 15, Article 100099. https://doi.org/10.1016/j.bbiosy.2024.100099

The bone-cartilage interface is defined by a unique arrangement of cells and tissue matrix. Injury to the interface can contribute to the development of arthritic joint disease. Attempts to repair osteochondral damage through clinical trials have gen... Read More about A phosphate glass reinforced composite acrylamide gradient scaffold for osteochondral interface regeneration..

PAMAM dendrimers as mediators of dermal and transdermal drug delivery: a review (2024)
Journal Article
Kirkby, M., Sabri, A. H. B., Holmes, A., Moss, G. P. J., & Scurr, D. (in press). PAMAM dendrimers as mediators of dermal and transdermal drug delivery: a review. Journal of Pharmacy and Pharmacology, 76(10), 1284–1300. https://doi.org/10.1093/jpp/rgae080

Objectives
Poly(amidoamine) dendrimers have been widely investigated as potential nanomaterials that can enhance the skin permeation of topically applied drugs. This article reviews the studies that have used dendrimers as penetration enhancers and... Read More about PAMAM dendrimers as mediators of dermal and transdermal drug delivery: a review.

Osteointegration of functionalised high-performance oxide ceramics: imaging from micro-computed tomography (2024)
Journal Article
Migliorini, F., Eschweiler, J., Betsch, M., Maffulli, N., Tingart, M., Hildebrand, F., Lecouturier, S., Rath, B., & Schenker, H. (2024). Osteointegration of functionalised high-performance oxide ceramics: imaging from micro-computed tomography. Journal of Orthopaedic Surgery and Research, 19(1), 1-8. https://doi.org/10.1186/s13018-024-04918-2

Background
This study evaluated the osseointegration potential of functionalised high-performance oxide ceramics (HPOC) in isolation or coated with BMP-2 or RGD peptides in 36 New Zeeland female rabbits using micro-computed tomography (micro CT). Th... Read More about Osteointegration of functionalised high-performance oxide ceramics: imaging from micro-computed tomography.