Defining optimal interventions for Perinatal Anxiety (PNA) in a primary care population: a multi-methods study (2024)
Thesis
Silverwood, V. A. Defining optimal interventions for Perinatal Anxiety (PNA) in a primary care population: a multi-methods study. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/1015697

Introduction
Perinatal anxiety (PNA) occurs during pregnancy and up to 12 months postpartum. PNA affects approximately 21% of women worldwide and can have a negative impact on mothers, children and their families. The National Institute for Health... Read More about Defining optimal interventions for Perinatal Anxiety (PNA) in a primary care population: a multi-methods study.

How does organisational culture facilitate uptake of home dialysis? An ethnographic study of kidney centres in England (2024)
Journal Article
Allen, K., Shaw, K. L., Spry, J. L., Dikomitis, L., Coyle, D., Damery, S., …Davies, S. (2024). How does organisational culture facilitate uptake of home dialysis? An ethnographic study of kidney centres in England. BMJ Open, 14(12), https://doi.org/10.1136/bmjopen-2024-085754

Objective: The proportion of people having home dialysis for kidney disease varies considerably by treating centre, socioeconomic deprivation levels in the area and to some extent ethnicity. This study aimed to gain in-depth insights into cultural an... Read More about How does organisational culture facilitate uptake of home dialysis? An ethnographic study of kidney centres in England.

Genotype‐Guided Asthma Treatment Reduces Exacerbations in Children: Meta‐Analysis of Two RCTs (2024)
Journal Article
Slob, E. M. A., Vijverberg, S. J. H., Ruffles, T., Noij, L. C. E., Biermann, J., Brouwer, A. F. J., …Maitland‐van der Zee, A. H. (in press). Genotype‐Guided Asthma Treatment Reduces Exacerbations in Children: Meta‐Analysis of Two RCTs. Allergy, https://doi.org/10.1111/all.16438

Background: Long‐acting beta2‐agonists (LABA) in combination with inhaled corticosteroids (ICS) are commonly used to treat asthma, however, some children lack response to the addition of LABA. This might be partially due to the presence of the Arg16G... Read More about Genotype‐Guided Asthma Treatment Reduces Exacerbations in Children: Meta‐Analysis of Two RCTs.

Rising mortality rates linked to type‐2 diabetes and obesity in the United States: An observational analysis from 1999 to 2022 (2024)
Journal Article
Ahmed, M., Nofal, A., Shafiq, A., Javaid, H., Ahsan, A., Nadeem, Z. A., …Fonarow, G. C. (in press). Rising mortality rates linked to type‐2 diabetes and obesity in the United States: An observational analysis from 1999 to 2022. Journal of Diabetes Investigation, https://doi.org/10.1111/jdi.14386

Background: The prevalence of type 2 diabetes (T2D) and obesity are increasing in the United States. However, population‐level data for mortality trends due to T2D and obesity are limited. This study aims to assess these death trends among adults in... Read More about Rising mortality rates linked to type‐2 diabetes and obesity in the United States: An observational analysis from 1999 to 2022.

What if the patient reads this? A student guide to writing in the GP electronic patient record (2024)
Journal Article
C, S., C, S., J, B., J, L., S, G., S C, S., …K, W. (in press). What if the patient reads this? A student guide to writing in the GP electronic patient record. Education for Primary Care, 1-6. https://doi.org/10.1080/14739879.2024.2435613

Background
It is common practice for senior medical students in UK General Practice to enter details of their consultations into the electronic patient record (EPR). There is evidence that students benefit educationally from writing in patient recor... Read More about What if the patient reads this? A student guide to writing in the GP electronic patient record.

Diagnosing and managing patients with heart failure with preserved ejection fraction: a consensus survey (2024)
Journal Article
Austin, R., Khair, E., Blakeman, T., Hossain, M. Z., Sowden, E., Chew-Graham, C., …Deaton, C. (2024). Diagnosing and managing patients with heart failure with preserved ejection fraction: a consensus survey. BMJ Open, 14(12), bmjopen-2024-092993. https://doi.org/10.1136/bmjopen-2024-092993

Aim: As heart failure (HF) with preserved ejection fraction (HFpEF) prevalence increases, it remains frequently underdiagnosed and poorly managed. Recent positive pharmacological trials have increased interest in HFpEF but challenges of diagnosis and... Read More about Diagnosing and managing patients with heart failure with preserved ejection fraction: a consensus survey.

Metformin for the Prevention of Antipsychotic-Induced Weight Gain: Guideline Development and Consensus Validation (2024)
Journal Article
Carolan, A., Hynes-Ryan, C., Agarwal, S. M., Bourke, R., Cullen, W., Gaughran, F., …O’Donoghue, B. (in press). Metformin for the Prevention of Antipsychotic-Induced Weight Gain: Guideline Development and Consensus Validation. Schizophrenia Bulletin, https://doi.org/10.1093/schbul/sbae205

Background Overweight and obesity are highly prevalent in people with severe mental illness (SMI). Antipsychotic-induced weight gain (AIWG) is one of the most commonly reported and distressing side effects of treatment and people living with SMI plac... Read More about Metformin for the Prevention of Antipsychotic-Induced Weight Gain: Guideline Development and Consensus Validation.

Trajectories of work absence in England due to a musculoskeletal or mental health condition: an electronic health record study (2024)
Thesis
Legha, A. S. Trajectories of work absence in England due to a musculoskeletal or mental health condition: an electronic health record study. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/956328

Introduction
Long-term sickness absence has recently been rising in the UK, causing a record number of economically inactive individuals and prompting concern from the Government. The aim of this thesis is to derive trajectories of absence over time... Read More about Trajectories of work absence in England due to a musculoskeletal or mental health condition: an electronic health record study.

The prognostic value of mean platelet volume in patients with coronary artery disease: An updated systematic review with meta-analyses. (2024)
Journal Article
Galimzhanov, A., Tun, H. N., Sabitov, Y., Perone, F., Kursat, T. M., Tenekecioglu, E., & Mamas, M. A. (in press). The prognostic value of mean platelet volume in patients with coronary artery disease: An updated systematic review with meta-analyses. European Journal of Clinical Investigation, Article e14295. https://doi.org/10.1111/eci.14295

Mean platelet volume (MPV) is a widely available laboratory index, however its prognostic significance in patients with coronary artery disease (CAD) is still unclear. We intended to investigate and pool the evidence on the prognostic utility of admi... Read More about The prognostic value of mean platelet volume in patients with coronary artery disease: An updated systematic review with meta-analyses..

General practice at the frontline of preventing suicide. (2024)
Journal Article
Steeg, S., & Mughal, F. (in press). General practice at the frontline of preventing suicide. British Journal of General Practice (BJGP), 74(745), 346. https://doi.org/10.3399/bjgp24X738825

Central and Eastern European Migrants in the United Kingdom: A Scoping Review of the Reasons for Utilisation of Transnational Healthcare (2024)
Journal Article
Stepanova, V., Poppleton, A., & Ponsford, R. (2024). Central and Eastern European Migrants in the United Kingdom: A Scoping Review of the Reasons for Utilisation of Transnational Healthcare. Health Expectations, 27(4), Article e14155. https://doi.org/10.1111/hex.14155

Background: An estimated 2.2 million people from Central and Eastern Europe (CEE) live in the United Kingdom. It has been documented that CEE migrants underutilise health services in the United Kingdom and, as an alternative, seek healthcare in their... Read More about Central and Eastern European Migrants in the United Kingdom: A Scoping Review of the Reasons for Utilisation of Transnational Healthcare.

Google Internet searches related to inflammatory arthritis: An observational study using Google Trends data (2024)
Journal Article
Akthar, M., Mason, K. J., & Scott, I. C. (2024). Google Internet searches related to inflammatory arthritis: An observational study using Google Trends data. Musculoskeletal Care, 22(3), Article e1916. https://doi.org/10.1002/msc.1916

Objective: The Internet has transformed how patients access health information. We examined Google search engine data to understand which aspects of health are most often searched for in combination with inflammatory arthritis (IA). Methods: Using Go... Read More about Google Internet searches related to inflammatory arthritis: An observational study using Google Trends data.

Exploring Experiences of People With Knee Osteoarthritis Who Received a Physiotherapist-Delivered Dietary Weight Loss and Exercise Intervention: A Mixed Methods Study. (2024)
Journal Article
Lawford, B. J., Allison, K., Nelligan, R., Campbell, P., Hinman, R. S., Jones, S. E., …Bennell, K. L. (2024). Exploring Experiences of People With Knee Osteoarthritis Who Received a Physiotherapist-Delivered Dietary Weight Loss and Exercise Intervention: A Mixed Methods Study. Arthritis Care & Research, https://doi.org/10.1002/acr.25401

Explore the experiences of people with knee osteoarthritis who received a very low energy diet (VLED) and exercise program from a physiotherapist. Mixed methods study involving questionnaires (n=42) and semi-structured interviews (n=22) with randomiz... Read More about Exploring Experiences of People With Knee Osteoarthritis Who Received a Physiotherapist-Delivered Dietary Weight Loss and Exercise Intervention: A Mixed Methods Study..

Musculoskeletal Health and Work: Development and Internal–External Cross-Validation of a Model to Predict Risk of Work Absence and Presenteeism in People Seeking Primary Healthcare (2024)
Journal Article
Archer, L., Peat, G., Snell, K. I. E., Hill, J. C., Dunn, K. M., Foster, N. E., …Wynne-Jones, G. (2024). Musculoskeletal Health and Work: Development and Internal–External Cross-Validation of a Model to Predict Risk of Work Absence and Presenteeism in People Seeking Primary Healthcare. Journal of Occupational Rehabilitation, https://doi.org/10.1007/s10926-024-10223-w

Purpose
To develop and validate prediction models for the risk of future work absence and level of presenteeism, in adults seeking primary healthcare with musculoskeletal disorders (MSD).

Methods
Six studies from the West-Midlands/Northwest regi... Read More about Musculoskeletal Health and Work: Development and Internal–External Cross-Validation of a Model to Predict Risk of Work Absence and Presenteeism in People Seeking Primary Healthcare.

Understanding the preferences of young adults with type 2 diabetes mellitus with regard to diabetes self-management education: a qualitative study (2024)
Journal Article
Sim, R. R. J., Soon, W., Smith, H. E., Griva, K., & Wong, S. K. W. (2024). Understanding the preferences of young adults with type 2 diabetes mellitus with regard to diabetes self-management education: a qualitative study. BMJ Open, 14(7), Article e086133. https://doi.org/10.1136/bmjopen-2024-086133

Aim: Young-onset type 2 diabetes (YOD) is associated with poorer clinical outcomes. To support the development of more effective diabetes self-management education (DSME) programmes, this study aimed to understand the preferences of young adults with... Read More about Understanding the preferences of young adults with type 2 diabetes mellitus with regard to diabetes self-management education: a qualitative study.

GPs’ views of prescribing beta- blockers for people with anxiety disorders: a qualitative study (2024)
Journal Article
Archer, C., Kessler, D., Wiles, N., Chew-Graham, C. A., & Turner, K. (2024). GPs’ views of prescribing beta- blockers for people with anxiety disorders: a qualitative study. British Journal of General Practice (BJGP), Article BJGP.2024.0091. https://doi.org/10.3399/BJGP.2024.0091

Between 2003-2018, incident prescriptions of beta-blockers for anxiety increased substantially, particularly in young adults. NICE guidance for anxiety does not recommend beta-blockers, probably due to a lack of evidence to support such use. Recent r... Read More about GPs’ views of prescribing beta- blockers for people with anxiety disorders: a qualitative study.

Community based complex interventions to sustain independence in older people: systematic review and network meta-analysis (2024)
Journal Article
Crocker, T. F., Ensor, J., Lam, N., Jordão, M., Bajpai, R., Bond, M., …Clegg, A. (2024). Community based complex interventions to sustain independence in older people: systematic review and network meta-analysis. BMJ, 384, Article e077764. https://doi.org/10.1136/bmj-2023-077764

To synthesise evidence of the effectiveness of community based complex interventions, grouped according to their intervention components, to sustain independence for older people. Systematic review and network meta-analysis. Medline, Embase, CINAHL,... Read More about Community based complex interventions to sustain independence in older people: systematic review and network meta-analysis.

The Extent to Which the Wish to Donate One’s Organs After Death Contributes to Life-Extension Arguments in Favour of Voluntary Active Euthanasia in the Terminally Ill: An Ethical Analysis (2024)
Journal Article
Armitage, R. C. (in press). The Extent to Which the Wish to Donate One’s Organs After Death Contributes to Life-Extension Arguments in Favour of Voluntary Active Euthanasia in the Terminally Ill: An Ethical Analysis. New Bioethics, 1-29. https://doi.org/10.1080/20502877.2024.2308346

In terminally ill individuals who would otherwise end their own lives, active voluntary euthanasia (AVE) can be seen as life-extending rather than life-shortening. Accordingly, AVE supports key pro-euthanasia arguments (appeals to autonomy and benefi... Read More about The Extent to Which the Wish to Donate One’s Organs After Death Contributes to Life-Extension Arguments in Favour of Voluntary Active Euthanasia in the Terminally Ill: An Ethical Analysis.

Counting the Lifetime Cost of Obesity: Analysis based on National England Data (2024)
Journal Article
Fryer, A. A., Heald, A., Stedman, M., Stedman, M., Davies, M. B., Rutter, M. K., …Whyte, M. (2024). Counting the Lifetime Cost of Obesity: Analysis based on National England Data. Diabetes, Obesity and Metabolism, 26(4), 1464-1478. https://doi.org/10.1111/dom.15447

Aim
Obesity has a significant impact on all-cause mortality rate and overall health care resource use (HCRU). These outcomes are also strongly linked to age, sex and local deprivation of the population. We aimed to establish the lifetime costs of ob... Read More about Counting the Lifetime Cost of Obesity: Analysis based on National England Data.

A Device for Prehabilitation of Total Knee Replacement Surgery (Slider): Usability Study. (2023)
Journal Article
Islam, R., Gooch, D., Karlakki, S., & Price, B. (in press). A Device for Prehabilitation of Total Knee Replacement Surgery (Slider): Usability Study. JMIR Formative Research, 7, e48055. https://doi.org/10.2196/48055

Rehabilitation, or "prehabilitation," is essential in preparing for and recovering from knee replacement surgery. The recent demand for these services has surpassed available resources, a situation further strained by the COVID-19 pandemic, which has... Read More about A Device for Prehabilitation of Total Knee Replacement Surgery (Slider): Usability Study..