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Isolation of genes controlling apoptosis through their effects on cell survival (2006)
Journal Article
Williams, G. T., Hughes, J. P., Stoneman, V., Anderson, C. L., McCarthy, N. J., Mourtada-Maarabouni, M., …Farzaneh, F. (2006). Isolation of genes controlling apoptosis through their effects on cell survival. Gene Therapy and Molecular Biology, 10(28), 255-262

The identification of the most suitable molecular targets for gene and drug therapy is the crucial first step in the development of new disease treatments. The rational identification of such targets depends on a detailed understanding of the patholo... Read More about Isolation of genes controlling apoptosis through their effects on cell survival.

The antiapoptotic RBM5/LUCA-15/H37 gene and its role in apoptosis and human cancer: Research update (2006)
Journal Article
Maarabouni, M. M., & Williams, G. T. (2006). The antiapoptotic RBM5/LUCA-15/H37 gene and its role in apoptosis and human cancer: Research update. Scientific World Journal, 1705 - 1712. https://doi.org/10.1100/tsw.2006.268

The candidate tumour-suppressor gene, LUCA-15/RBM5/H37, maps to the lung cancer tumour-suppressor locus 3p21.3. The LUCA-15 gene locus encodes at least four alternatively spliced transcripts that have been shown to function as regulators of apoptosis... Read More about The antiapoptotic RBM5/LUCA-15/H37 gene and its role in apoptosis and human cancer: Research update.

The effect of Plasmodium falciparum infection on expression of monocyte surface molecules (2006)
Journal Article
Jenkins, N., Chakravorty, S., Urban, B., Kai, O., Marsh, K., & Craig, A. (2006). The effect of Plasmodium falciparum infection on expression of monocyte surface molecules. Transactions of The Royal Society of Tropical Medicine and Hygiene, 100(11), 1007-1012. https://doi.org/10.1016/j.trstmh.2006.01.005

Plasmodium falciparum infection may result in severe malaria in susceptible individuals. The pathogenesis of severe disease is probably a combination of the sequestration of infected erythrocytes and overstimulation of the immune response. Monocytes... Read More about The effect of Plasmodium falciparum infection on expression of monocyte surface molecules.

Ballooning dispersal in arthropod taxa with convergent behaviours: dynamic properties of ballooning silk in turbulent flows (2006)
Journal Article
Reynolds, A., Bohan, D., & Bell, J. (2006). Ballooning dispersal in arthropod taxa with convergent behaviours: dynamic properties of ballooning silk in turbulent flows. Biology Letters, 2(3), 371–373. https://doi.org/10.1098/rsbl.2006.0486

We present a new model of ballooning behaviour in arthropods in which draglines are regarded as being extendible and completely flexible. Our numerical simulations reveal that silk draglines within turbulent flows can become twisted and stretched int... Read More about Ballooning dispersal in arthropod taxa with convergent behaviours: dynamic properties of ballooning silk in turbulent flows.

Water quality and immatures of the M and S forms of Anopheles gambiae s.s. and An. arabiensis in a Malian village (2006)
Journal Article
(2006). Water quality and immatures of the M and S forms of Anopheles gambiae s.s. and An. arabiensis in a Malian village. Malaria Journal, https://doi.org/10.1186/1475-2875-5-35

Introduction
The associations between the immatures of Anopheles gambiae s.s. (Diptera: Culicidae), its M and S forms, and Anopheles arabiensis among and within larval breeding habitats in Banambani, Mali were investigated under varying conditions o... Read More about Water quality and immatures of the M and S forms of Anopheles gambiae s.s. and An. arabiensis in a Malian village.

Candidate tumor suppressor LUCA-15/RBM5/H37 modulates expression of apoptosis and cell cycle genes (2006)
Journal Article
Mourtada-Maarabouni, M., Keen, J., Clark, J., Cooper, C. S., & Williams, G. T. (2006). Candidate tumor suppressor LUCA-15/RBM5/H37 modulates expression of apoptosis and cell cycle genes. Experimental Cell Research, 312(10), 1745-1752. https://doi.org/10.1016/j.yexcr.2006.02.009

RBM5 (RNA-binding motif protein 5/LUCA-15/H37) is encoded at the lung cancer tumor suppressor locus 3p21.3 and itself has several important characteristics of a tumor suppressor, including both potentiation of apoptosis and inhibition of the cell cyc... Read More about Candidate tumor suppressor LUCA-15/RBM5/H37 modulates expression of apoptosis and cell cycle genes.

Water quality and immatures of the M and S forms of Anopheles gambiae s.s. and An. arabiensis in a Malian village (2006)
Journal Article
(2006). Water quality and immatures of the M and S forms of Anopheles gambiae s.s. and An. arabiensis in a Malian village. Malaria Journal, 35 -?. https://doi.org/10.1186/1475-2875-5-35

INTRODUCTION: The associations between the immatures of Anopheles gambiae s.s. (Diptera: Culicidae), its M and S forms, and Anopheles arabiensis among and within larval breeding habitats in Banambani, Mali were investigated under varying conditions o... Read More about Water quality and immatures of the M and S forms of Anopheles gambiae s.s. and An. arabiensis in a Malian village.

The emergence of manipulative experiments in ecological spider research (1684-1973) (2005)
Journal Article
Bell, J. R. (2005). The emergence of manipulative experiments in ecological spider research (1684-1973). Journal of Arachnology, 33(3), 826-849. https://doi.org/10.1636/0161-8202%282005%29033%5B0826%3ATEOMEI%5D2.0.CO%3B2

The history of spider ecology is discussed from its early beginnings in 1684 when the natural historian Martin Lister published his observations, to the post-war period up until 1973 when ecological spider research gathered momentum. While there have... Read More about The emergence of manipulative experiments in ecological spider research (1684-1973).

Detection of secondary predation by PCR analyses of the gut contents of invertebrate generalist predators (2005)
Journal Article
SHEPPARD, S., BELL, J., SUNDERLAND, K., FENLON, J., SKERVIN, D., & SYMONDSON, W. (2005). Detection of secondary predation by PCR analyses of the gut contents of invertebrate generalist predators. Molecular Ecology, 14(14), 4461-4468. https://doi.org/10.1111/j.1365-294X.2005.02742.x

Predation by generalist predators is difficult to study in the field because of the complex effects of positive and negative interactions within and between predator species and guilds. Predation can be monitored by molecular means, through identific... Read More about Detection of secondary predation by PCR analyses of the gut contents of invertebrate generalist predators.

Can simple experimental electronics simulate the dispersal phase of spider ballooners? (2005)
Journal Article
Bell, J. R., Bohan, D. A., Le Fevre, R., & Weyman, G. S. (2005). Can simple experimental electronics simulate the dispersal phase of spider ballooners?. Journal of Arachnology, 33(2), 523-532. https://doi.org/10.1636/04-91.1

Here we describe the structure of a fall speed chamber designed to measure, with low experimental error, the terminal velocities (fall speeds) of spiders of known weight and a given length of silk. We also describe the construction of a simulated ind... Read More about Can simple experimental electronics simulate the dispersal phase of spider ballooners?.

PfEMP1 expression is reduced on the surface of knoblessPlasmodium falciparuminfected erythrocytes (2005)
Journal Article
Horrocks, P., Pinches, R. A., Chakravorty, S. J., Papakrivos, J., Christodoulou, Z., Kyes, S. A., …Newbold, C. I. (2005). PfEMP1 expression is reduced on the surface of knoblessPlasmodium falciparuminfected erythrocytes. Journal of Cell Science, 118(11), 2507-2518. https://doi.org/10.1242/jcs.02381

The Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) is a key virulence factor for this species of human malarial parasite. PfEMP1 is expressed on the surface of infected erythrocytes (IEs) and directly mediates adhesion to a variety of... Read More about PfEMP1 expression is reduced on the surface of knoblessPlasmodium falciparuminfected erythrocytes.

Functional expression cloning reveals a central role for the receptor for activated protein kinase C 1 (RACK1) in T cell apoptosis (2005)
Journal Article
Mourtada-Maarabouni, M., Kirkham, L., Farzaneh, F., & Williams, G. T. (2005). Functional expression cloning reveals a central role for the receptor for activated protein kinase C 1 (RACK1) in T cell apoptosis. Journal of Leukocyte Biology, 78(2), 503–514. https://doi.org/10.1189/jlb.0205070

Mammalian cDNA expression cloning was used to identify novel genes that regulate apoptosis. Using a functional screen, we identified a partial cDNA for the receptor for activated protein kinase C 1 (RACK1) through selection for resistance to phytohem... Read More about Functional expression cloning reveals a central role for the receptor for activated protein kinase C 1 (RACK1) in T cell apoptosis.

Ballooning dispersal using silk: world fauna, phylogenies, genetics and models (2005)
Journal Article
Bell, J., Bohan, D., Shaw, E., & Weyman, G. (2005). Ballooning dispersal using silk: world fauna, phylogenies, genetics and models. Bulletin of Entomological Research, 95(2), 69 - 114. https://doi.org/10.1079/BER2004350

Aerial dispersal using silk (‘ballooning’) has evolved in spiders (Araneae), spider mites (Acari) and in the larvae of moths (Lepidoptera). Since the 17th century, over 500 observations of ballooning behaviours have been published, yet there is an ab... Read More about Ballooning dispersal using silk: world fauna, phylogenies, genetics and models.

Herpesvirus pan encodes a functional homologue of BHRF1, the Epstein-Barr virus v-Bcl-2 (2005)
Journal Article
(2005). Herpesvirus pan encodes a functional homologue of BHRF1, the Epstein-Barr virus v-Bcl-2. BMC microbiology, 6 -?. https://doi.org/10.1186/1471-2180-5-6

BACKGROUND: Epstein-Barr virus (EBV) latently infects about 90% of the human population and is associated with benign and malignant diseases of lymphoid and epithelial origin. BHRF1, an early lytic cycle antigen, is an apoptosis suppressing member of... Read More about Herpesvirus pan encodes a functional homologue of BHRF1, the Epstein-Barr virus v-Bcl-2.

The role of ICAM-1 in Plasmodium falciparum cytoadherence (2004)
Journal Article
Chakravorty, S. J., & Craig, A. (2005). The role of ICAM-1 in Plasmodium falciparum cytoadherence. European Journal of Cell Biology, 84(1), 15-27. https://doi.org/10.1016/j.ejcb.2004.09.002

Parasite sequestration at microvascular sites is a fundamental phenomenon in the manifestation of the symptoms of malaria and the progression to severe disease. Here, we review the endothelial cell-expressed intercellular adhesion molecule-1 (ICAM-1)... Read More about The role of ICAM-1 in Plasmodium falciparum cytoadherence.

Regulation of apoptosis by fau revealed by functional expression cloning and antisense expression (2004)
Journal Article
Mourtada-Maarabouni, M., Kirkham, L., Farzaneh, F., & Williams, G. T. (2004). Regulation of apoptosis by fau revealed by functional expression cloning and antisense expression. Oncogene, 23, 9419–9426. https://doi.org/10.1038/sj.onc.1208048

Functional expression cloning is a powerful strategy for identifying critical steps in biological pathways independently of prior assumptions. It is particularly suitable for the identification of molecules crucial to the control of apoptosis. Our sc... Read More about Regulation of apoptosis by fau revealed by functional expression cloning and antisense expression.

Isolation and characterization of a novel pituitary tumor apoptosis gene (2004)
Journal Article
Bahar, A., Simpson, D. J., Cutty, S. J., Bicknell, J. E., Hoban, P. R., Holley, S., …Farrell, W. E. (2004). Isolation and characterization of a novel pituitary tumor apoptosis gene. Molecular Endocrinology, 18(7), https://doi.org/10.1210/me.2004-0087

To determine mechanisms for pituitary neoplasia we used methylation-sensitive arbitrarily primed-PCR to isolate novel genes that are differentially methylated relative to normal pituitary. We report the isolation of a novel differentially methylated... Read More about Isolation and characterization of a novel pituitary tumor apoptosis gene.