Management of Refractory Disease and Persistent Symptoms in Inflammatory Arthritis: Qualitative Framework analysis of interviews with patients and healthcare professionals (2024)
Journal Article
Chaplin, H., Simpson, C., Wilkins, K., Meehan, J., Ng, N., Galloway, J., Lempp, H., Scott, I. C., Sen, D., Tattersall, R., Moss-Morris, R., & Norton, S. (2024). Management of Refractory Disease and Persistent Symptoms in Inflammatory Arthritis: Qualitative Framework analysis of interviews with patients and healthcare professionals. Rheumatology Advances in Practice, 8(3), Article rkae076. https://doi.org/10.1093/rap/rkae076

Objectives
This study aims to explore patients’ and clinicians’ experiences in managing and living with refractory disease (RD) and persistent physical and emotional symptoms (PPES) in patients with RA or polyarticular JIA from their perspectives th... Read More about Management of Refractory Disease and Persistent Symptoms in Inflammatory Arthritis: Qualitative Framework analysis of interviews with patients and healthcare professionals.

Aperiodic and Hurst EEG exponents across early human brain development: A systematic review (2024)
Journal Article
Stanyard, R., Mason, D., Ellis, C., Dickson, H., Short, R., Batalle, D., & Arichi, T. (2024). Aperiodic and Hurst EEG exponents across early human brain development: A systematic review. Developmental Cognitive Neuroscience, 68, Article 101402. https://doi.org/10.1016/j.dcn.2024.101402

In electroencephalographic (EEG) data, power-frequency slope exponents (1/f_β) can provide non-invasive markers of in vivo neural activity excitation-inhibition (E:I) balance. E:I balance may be altered in neurodevelopmental conditions; hence, unders... Read More about Aperiodic and Hurst EEG exponents across early human brain development: A systematic review.

BEBOP V. Homogeneous stellar analysis of potential circumbinary planet hosts (2024)
Journal Article
Freckelton, A. V., Sebastian, D., Mortier, A., Triaud, A. H. M. J., Maxted, P. F. L., Acuña, L., Armstrong, D. J., Battley, M. P., Baycroft, T. A., Boisse, I., Bourrier, V., Carmona, A., Coleman, G. A. L., Cameron, A. C., Cortés-Zuleta, P., Delfosse, X., Dransfield, G., Duck, A., Forveille, T., French, J. R., …Willett, E. (2024). BEBOP V. Homogeneous stellar analysis of potential circumbinary planet hosts. Monthly Notices of the Royal Astronomical Society, 531(4), 4085-4098. https://doi.org/10.1093/mnras/stae1405

Planets orbiting binary systems are relatively unexplored compared to those around single stars. Detections of circumbinary planets and planetary systems offer a first detailed view into our understanding of circumbinary planet formation and dynamica... Read More about BEBOP V. Homogeneous stellar analysis of potential circumbinary planet hosts.

3D simulations of a neon burning convective shell in a massive star (2024)
Journal Article
Georgy, C., Rizzuti, F., Hirschi, R., Varma, V., Arnett, W. D., Meakin, C., Mocak, M., Murphy, A. S., & Rauscher, T. (2024). 3D simulations of a neon burning convective shell in a massive star. Monthly Notices of the Royal Astronomical Society, 531(4), 4293–4310. https://doi.org/10.1093/mnras/stae1381

The treatment of convection remains a major weakness in the modelling of stellar evolution with one-dimensional (1D) codes. The ever increasing computing power makes now possible to simulate in 3D part of a star for a fraction of its life, allowing u... Read More about 3D simulations of a neon burning convective shell in a massive star.

3D simulations of convective shell Neon-burning in a massive star (2024)
Preprint / Working Paper
Georgy, C., Rizzuti, F., Hirschi, R., Varma, V., D. Arnett, W., Meakin, C., Mocak, M., StJ. Murphy, A., & Rauscher, T. 3D simulations of convective shell Neon-burning in a massive star

The treatment of convection remains a major weakness in the modelling of stellar evolution with one-dimensional (1D) codes. The ever increasing computing power makes now possible to simulate in 3D part of a star for a fraction of its life, allowing u... Read More about 3D simulations of convective shell Neon-burning in a massive star.

Seven new triply eclipsing triple star systems (2024)
Journal Article
Rappaport, S. A., Borkovits, T., Mitnyan, T., Gagliano, R., Eisner, N., Jacobs, T., Tokovinin, A., Powell, B., Kostov, V., Omohundro, M., Kristiansen, M. H., Jayaraman, R., Terentev, I., Schwengeler, H. M., LaCourse, D., Garai, Z., Pribulla, T., Maxted, P. F. L., Bíró, I. B., Csányi, I., …Vanderburg, A. (2024). Seven new triply eclipsing triple star systems. Astronomy & Astrophysics, 686(A27), https://doi.org/10.1051/0004-6361/202449273

Aims. We have identified nearly a hundred close triply eclipsing hierarchical triple star systems from data taken with the space telescope TESS. These systems are noteworthy in that we can potentially determine their dynamical and astrophysical param... Read More about Seven new triply eclipsing triple star systems.

Biocatalytic Nucleobase Diversification of 4'‐Thionucleosides and Application of Derived 5‐Ethynyl‐4'‐thiouridine for RNA synthesis detection (2024)
Journal Article
Westarp, S., Benckendorff, C., Motter, J., Rohrs, V., Sanghvi, Y., Neubauer, P., Kurreck, J., Kurreck, A., & Miller, G. J. (in press). Biocatalytic Nucleobase Diversification of 4'‐Thionucleosides and Application of Derived 5‐Ethynyl‐4'‐thiouridine for RNA synthesis detection. Angewandte Chemie, Article e202405040. https://doi.org/10.1002/ange.202405040

Nucleoside and nucleotide analogues have proven to be transformative in the treatment of viral infections and cancer. One branch of structural modification to deliver new nucleoside analogue classes explores replacement of canonical ribose oxygen wit... Read More about Biocatalytic Nucleobase Diversification of 4'‐Thionucleosides and Application of Derived 5‐Ethynyl‐4'‐thiouridine for RNA synthesis detection.

Biocatalytic Nucleobase Diversification of 4'-Thionucleosides and Application of Derived 5-Ethynyl-4'-thiouridine for RNA synthesis detection. (2024)
Journal Article
Westarp, S., Benckendorff, C., Motter, J., Rohrs, V., Sanghvi, Y., Neubauer, P., Kurreck, J., Kurreck, A., & Miller, G. J. (in press). Biocatalytic Nucleobase Diversification of 4'-Thionucleosides and Application of Derived 5-Ethynyl-4'-thiouridine for RNA synthesis detection. Angewandte Chemie, Article e202405040. https://doi.org/10.1002/anie.202405040

Nucleoside and nucleotide analogues have proven to be transformative in the treatment of viral infections and cancer. One branch of structural modification to deliver new nucleoside analogue classes explores replacement of canonical ribose oxygen wit... Read More about Biocatalytic Nucleobase Diversification of 4'-Thionucleosides and Application of Derived 5-Ethynyl-4'-thiouridine for RNA synthesis detection..

3’-O-β-Glycosylation of nucleoside analogues using a promiscuous bacterial glycosyltransferase (2024)
Working Paper
Dolan, J., Keenan, T., Benckendorff, C., Ní Cheallaigh, A., Fascione, M., & Miller, G. 3’-O-β-Glycosylation of nucleoside analogues using a promiscuous bacterial glycosyltransferase

Conceptualizing decent work: an explorative study of decent work in England’s Midlands region (2024)
Journal Article
Dobbins, T., Cao, X., Green, A., Johnstone, P., & Foster, W. (2024). Conceptualizing decent work: an explorative study of decent work in England’s Midlands region. Policy Studies, 1-22. https://doi.org/10.1080/01442872.2024.2353068

Despite an increased focus on the quality as well as quantity of work, conceptualisation of decent work remains underdeveloped. There is no single agreed definition of decent work. The ILO (1999) provides an overarching definition of decent work as ‘... Read More about Conceptualizing decent work: an explorative study of decent work in England’s Midlands region.

Prognostic Factors and Models for Predicting Work Absence in Adults with Musculoskeletal Conditions Consulting a Healthcare Practitioner: A Systematic Review. (2024)
Journal Article
Wynne-Jones, G., Wainwright, E., Goodson, N., Jordan, J., Legha, A., Parchment, M., Wilkie, R., & Peat, G. (2024). Prognostic Factors and Models for Predicting Work Absence in Adults with Musculoskeletal Conditions Consulting a Healthcare Practitioner: A Systematic Review. Journal of Occupational Rehabilitation, https://doi.org/10.1007/s10926-024-10205-y

It is difficult to predict which employees, in particular those with musculoskeletal pain, will return to work quickly without additional vocational advice and support, which employees will require this support and what levels of support are most app... Read More about Prognostic Factors and Models for Predicting Work Absence in Adults with Musculoskeletal Conditions Consulting a Healthcare Practitioner: A Systematic Review..

An extended low-density atmosphere around the Jupiter-sized planet WASP-193 b (2024)
Journal Article
Barkaoui, K., Pozuelos, F. J., Hellier, C., Smalley, B., Nielsen, L. D., Niraula, P., Gillon, M., de Wit, J., Müller, S., Dorn, C., Helled, R., Jehin, E., Demory, B.-O., Van Grootel, V., Soubkiou, A., Ghachoui, M., Anderson, D. R., Benkhaldoun, Z., Bouchy, F., Burdanov, A., …West, R. G. (2024). An extended low-density atmosphere around the Jupiter-sized planet WASP-193 b. Nature Astronomy, https://doi.org/10.1038/s41550-024-02259-y

Gas giants transiting bright nearby stars provide crucial insights into planetary system formation and evolution mechanisms. Most of these planets show certain average characteristics, serving as benchmarks for our understanding of planetary systems.... Read More about An extended low-density atmosphere around the Jupiter-sized planet WASP-193 b.

Hypervalent iodine mediated cyclization of bishomoallylamides to prolinols (2024)
Working Paper
Butt, S. E., Kepski, K., Sotiropoulos, J.-M., & Moran, W. J. Hypervalent iodine mediated cyclization of bishomoallylamides to prolinols

A change in mechanism was observed in the hypervalent iodine mediated cyclization of N-alkenylamides when the carbon chain between the alkene and the amide increased from two to three atoms. In the latter case, cyclization at the amide nitrogen to fo... Read More about Hypervalent iodine mediated cyclization of bishomoallylamides to prolinols.

Magma recharge in persistently active basaltic–andesite systems and its geohazards implications: the case of Villarrica volcano, Chile (2024)
Journal Article
Cortés, J. A., Gertisser, R., & Calder, E. S. (2024). Magma recharge in persistently active basaltic–andesite systems and its geohazards implications: the case of Villarrica volcano, Chile. International Journal of Earth Sciences, 113, 1145–1163. https://doi.org/10.1007/s00531-024-02414-w

We report whole-rock chemistry, mineral chemistry, and volatile content from Villarrica volcano’s major recent paroxysms and background activity. Composition of the volcanic products are basalt to basaltic andesite with whole-rock SiO2 content betwee... Read More about Magma recharge in persistently active basaltic–andesite systems and its geohazards implications: the case of Villarrica volcano, Chile.

The tidal deformation and atmosphere of WASP-12 b from its phase curve (2024)
Journal Article
Akinsanmi, B., Barros, S. C. C., Lendl, M., Carone, L., Cubillos, P. E., Bekkelien, A., Fortier, A., Florén, H.-G., Collier Cameron, A., Boué, G., Bruno, G., Demory, B.-O., Brandeker, A., Sousa, S. G., Wilson, T. G., Deline, A., Bonfanti, A., Scandariato, G., Hooton, M. J., Correia, A. C. M., …Walton, N. A. (2024). The tidal deformation and atmosphere of WASP-12 b from its phase curve. Astronomy & Astrophysics, 685, Article A63. https://doi.org/10.1051/0004-6361/202348502

Context. Ultra-hot Jupiters present a unique opportunity to understand the physics and chemistry of planets, their atmospheres, and interiors at extreme conditions. WASP-12 b stands out as an archetype of this class of exoplanets, with a close-in orb... Read More about The tidal deformation and atmosphere of WASP-12 b from its phase curve.

Calibration plots for multistate risk predictions models (2024)
Journal Article
Pate, A., Sperrin, M., Riley, R. D., Peek, N., Van Staa, T., Sergeant, J. C., Mamas, M. A., Lip, G. Y. H., O'Flaherty, M., Barrowman, M., Buchan, I., & Martin, G. P. (in press). Calibration plots for multistate risk predictions models. Statistics in Medicine, https://doi.org/10.1002/sim.10094

Introduction
There is currently no guidance on how to assess the calibration of multistate models used for risk prediction. We introduce several techniques that can be used to produce calibration plots for the transition probabilities of a multistat... Read More about Calibration plots for multistate risk predictions models.

Identifying archived insect bulk samples using DNA metabarcoding: A case study using the long-term Rothamsted Insect Survey (2024)
Journal Article
Petsopoulos, D., Cuff, J. P., Bell, J. R., Kitson, J. J. N., Collins, L., Boonham, N., Morales‐Hojas, R., & Evans, D. M. (2024). Identifying archived insect bulk samples using DNA metabarcoding: A case study using the long-term Rothamsted Insect Survey. Environmental DNA, 6(3), e542. https://doi.org/10.1002/edn3.542

Insect populations are declining in many parts of the world, but a lack of long-term monitoring data is impeding our ability to understand and mitigate the causes of insect biodiversity loss. Whilst high-throughput sequencing (HTS) approaches, such a... Read More about Identifying archived insect bulk samples using DNA metabarcoding: A case study using the long-term Rothamsted Insect Survey.

Development of the Community-based complex Interventions to sustain Independence in Older People (CII-OP) typology: a qualitative synthesis of interventions in randomised controlled trials (2024)
Journal Article
Crocker, T. F., Jordão, M., Lam, N., Ramiz, R., Mirza, L., Patel, I., Ellwood, A., Patetsini, E., Ensor, J., Forster, A., Clegg, A., Gladman, J., Andre, D., Bajpai, R., Bond, M., Green, J., Morgan, J., Riley, R. D., & Walford, R. (2024). Development of the Community-based complex Interventions to sustain Independence in Older People (CII-OP) typology: a qualitative synthesis of interventions in randomised controlled trials. Age and ageing, 53(5), 1-13. https://doi.org/10.1093/ageing/afae102

Introduction Community-based services to sustain independence for older people have varying configurations. A typology of these interventions would improve service provision and research by providing conceptual clarity and enabling the identification... Read More about Development of the Community-based complex Interventions to sustain Independence in Older People (CII-OP) typology: a qualitative synthesis of interventions in randomised controlled trials.

Discovery of two warm mini-Neptunes with contrasting densities orbiting the young K3V star TOI-815 (2024)
Journal Article
Psaridi, A., Osborn, H., Bouchy, F., Lendl, M., Parc, L., Billot, N., Broeg, C., Sousa, S. G., Adibekyan, V., Attia, O., Bonfanti, A., Chakraborty, H., Collins, K. A., Davoult, J., Delgado-Mena, E., Grieves, N., Guillot, T., Heitzmann, A., Helled, R., Hellier, C., …West, R. G. (2024). Discovery of two warm mini-Neptunes with contrasting densities orbiting the young K3V star TOI-815. Astronomy & Astrophysics, 685, Article A5. https://doi.org/10.1051/0004-6361/202348678

We present the discovery and characterization of two warm mini-Neptunes transiting the K-V star TOI-815 in a K-M binary system. Analysis of its spectra and rotation period reveal the star to be young, with an age of 200(-200)(+400) Myr. TOI-815b has... Read More about Discovery of two warm mini-Neptunes with contrasting densities orbiting the young K3V star TOI-815.

Bisphosphonate alternative regimens for the prevention of osteoporotic fragility fractures: BLAST-OFF, a mixed-methods study (2024)
Report
Sahota, O., Narayanasamy, M., Bastounis, A., Paskins, Z., Bishop, S., Langley, T., Gittoes, N., Davis, S., Baily, A., Holmes, M., & Leonardi-Bee, J. (2024). Bisphosphonate alternative regimens for the prevention of osteoporotic fragility fractures: BLAST-OFF, a mixed-methods study. Secretary of State for Health and Social Care / NIHR

Bisphosphonates are a class of medication commonly used to treat osteoporosis. Alendronate is recommended as the first-line treatment; however, long-term adherence (both treatment compliance and persistence) is poor. Alternative bisphosphonates are a... Read More about Bisphosphonate alternative regimens for the prevention of osteoporotic fragility fractures: BLAST-OFF, a mixed-methods study.