CD4+TGFβ+ cells infiltrated the bursa of Fabricius following IBDV infection, and correlated with a delayed viral clearance, but did not correlate with disease severity, or immunosuppression (2023)
Journal Article
Nazki, S., Reddy, V. R. A. P., Kamble, N., Sadeyen, J.-R., Iqbal, M., Behboudi, S., Shelton, H., & Broadbent, A. J. (in press). CD4+TGFβ+ cells infiltrated the bursa of Fabricius following IBDV infection, and correlated with a delayed viral clearance, but did not correlate with disease severity, or immunosuppression. Frontiers in Immunology, 14, https://doi.org/10.3389/fimmu.2023.1197746

Introduction: Infectious Bursal Disease Virus (IBDV) causes immunosuppression in chickens. While B-cell destruction is the main cause of humoral immunosuppression, bursal T cells from IBDV-infected birds have been reported to inhibit the mitogenic re... Read More about CD4+TGFβ+ cells infiltrated the bursa of Fabricius following IBDV infection, and correlated with a delayed viral clearance, but did not correlate with disease severity, or immunosuppression.

Compromise and complicity: partnership and interdependence in a global challenges research collaboration (2023)
Journal Article
Palladino, M., Jeffery, L., Benslimane, D., & Arfaoui, O. (2023). Compromise and complicity: partnership and interdependence in a global challenges research collaboration. Global Social Challenges, 1-19. https://doi.org/10.1332/27523349y2023d000000001

This article contributes to debates on international collaborations by examining contradictions between the decolonial turn and the UK’s Global Challenges Research Fund which imposed Global North leadership on Global South partners. Through the lense... Read More about Compromise and complicity: partnership and interdependence in a global challenges research collaboration.

Uniform approximations and effective boundary conditions for a high-contrast elastic interface (2023)
Journal Article
Chapman, C. J., & Mogilevskaya, S. G. (2023). Uniform approximations and effective boundary conditions for a high-contrast elastic interface. Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences, 479(2277), 1 - 22. https://doi.org/10.1098/rspa.2023.0140

A difficulty in the theory of a thin elastic interface is that series expansions in its thickness become disordered in the high-contrast limit, i.e. when the interface is much softer or much stiffer than the media on either side. We provide a mathema... Read More about Uniform approximations and effective boundary conditions for a high-contrast elastic interface.

Interaction between pentacene molecules and monolayer transition metal dichalcogenides (2023)
Journal Article
Black, E., Kratzer, P., & Morbec, J. M. (2023). Interaction between pentacene molecules and monolayer transition metal dichalcogenides. Physical Chemistry Chemical Physics, 25(43), 29444-29450. https://doi.org/10.1039/d3cp01895d

Using first-principles calculations based on density-functional theory, we investigated the adsorption of pentacene molecules on monolayer two-dimensional transition metal dichalcogenides (TMD). We considered the four most popular TMDs, namely, MoS2,... Read More about Interaction between pentacene molecules and monolayer transition metal dichalcogenides.

Preparation of a 4′‐Thiouridine Building‐Block for Solid‐Phase Oligonucleotide Synthesis (2023)
Journal Article
Benckendorff, C. M. M., Sanghvi, Y. S., & Miller, G. J. (2023). Preparation of a 4′‐Thiouridine Building‐Block for Solid‐Phase Oligonucleotide Synthesis. Current Protocols in Neuroscience, 3(9), Article e878. https://doi.org/10.1002/cpz1.878

Starting from a commercially available thioether, we report a nine‐step synthesis of a 4′‐thiouridine phosphoramidite building‐block. We install the uracil nucleobase using Pummerer‐type glycosylation of a sulfoxide intermediate followed by a series... Read More about Preparation of a 4′‐Thiouridine Building‐Block for Solid‐Phase Oligonucleotide Synthesis.

TOI-332 b: A super dense Neptune found deep within the Neptunian desert (2023)
Journal Article
Osborn, A., Armstrong, D. J., Fernández, J. F., Knierim, H., Adibekyan, V., Collins, K. A., Delgado-Mena, E., Fridlund, M., da Silva, J. G., Hellier, C., Jackson, D. G., King, G. W., Lillo-Box, J., Matson, R. A., Matthews, E. C., Santos, N. C., Sousa, S. G., Stassun, K. G., Tan, T.-G., Ricker, G. R., …Wheatley, P. J. (in press). TOI-332 b: A super dense Neptune found deep within the Neptunian desert. Monthly Notices of the Royal Astronomical Society, 526(1), 548-566. https://doi.org/10.1093/mnras/stad2575

To date, thousands of planets have been discovered, but there are regions of the orbital parameter space that are still bare. An example is the short period and intermediate mass/radius space known as the ‘Neptunian desert’, where planets should be e... Read More about TOI-332 b: A super dense Neptune found deep within the Neptunian desert.

Stellar wind yields of very massive stars (2023)
Journal Article
Higgins, E. R., Vink, J. S., Hirschi, R., Laird, A. M., & Sabhahit, G. N. (in press). Stellar wind yields of very massive stars. Monthly Notices of the Royal Astronomical Society, 526(1), 534–547. https://doi.org/10.1093/mnras/stad2537

The most massive stars provide an essential source of recycled material for young clusters and galaxies. While very massive stars (VMS, M>100 $\rm {\rm M}_{\odot }$) are relatively rare compared to O stars, they lose disproportionately large a... Read More about Stellar wind yields of very massive stars.

Computations and Measurements of the Magnetic Polarizability Tensor Characterisation of Highly Conducting and Magnetic Objects (2023)
Journal Article
Elgy, J., Ledger, P. D., Davidson, J. L., Özdeger, T., & Peyton, A. J. (2023). Computations and Measurements of the Magnetic Polarizability Tensor Characterisation of Highly Conducting and Magnetic Objects. Engineering Computations, 40(7/8), 1778-1806. https://doi.org/10.1108/EC-11-2022-0688

Purpose
The ability to characterise highly conducting objects, that may also be highly magnetic, by the complex symmetric rank–2 magnetic polarizability tensor (MPT) is important for metal detection applications including discriminating between thre... Read More about Computations and Measurements of the Magnetic Polarizability Tensor Characterisation of Highly Conducting and Magnetic Objects.

Virtual screening, identification and in vitro validation of small molecule GDP-mannose dehydrogenase inhibitors † (2023)
Journal Article
Dolan, J., Ahmadipour, S., Wahart, A., Ni Cheallaigh, A., Sari, S., Eurtivong,, C., Lima, M., Skidmore, M., Volcho, K., Reynisson, J., Field, R., & Miller, G. (2023). Virtual screening, identification and in vitro validation of small molecule GDP-mannose dehydrogenase inhibitors †. RSC Chemical Biology, 4(11), 865-870. https://doi.org/10.1039/D3CB00126A

Upon undergoing mucoid conversion within the lungs of cystic fibrosis patients, the pathogenic bacterium Pseudomonas aeruginosa synthesises copious quantities of the virulence factor and exopolysaccharide alginate. The enzyme guanosine diphosphate ma... Read More about Virtual screening, identification and in vitro validation of small molecule GDP-mannose dehydrogenase inhibitors †.

Hubble Space Telescope imaging of the compact elliptical galaxy M32 reveals a dearth of carbon stars (2023)
Journal Article
Jones, O. C., Boyer, M. L., McDonald, I., Meixner, M., & van Loon, J. T. (2023). Hubble Space Telescope imaging of the compact elliptical galaxy M32 reveals a dearth of carbon stars. Monthly Notices of the Royal Astronomical Society, 525(3), 3693-3702. https://doi.org/10.1093/mnras/stad2472

We present new Hubble Space Telescope WFC3/IR medium-band photometry of the compact elliptical galaxy M32, chemically resolving its thermally pulsating asymptotic giant branch stars. We find 2829 M-type stars and 57 C stars. The carbon stars are like... Read More about Hubble Space Telescope imaging of the compact elliptical galaxy M32 reveals a dearth of carbon stars.

First light and reionisation epoch simulations (FLARES) – VIII. The emergence of passive galaxies at z ≥ 5 (2023)
Journal Article
Lovell, C. C., Roper, W., Vijayan, A. P., Seeyave, L., Irodotou, D., Wilkins, S. M., Conselice, C. J., Fortuni, F., Kuusisto, J. K., Merlin, E., Santini, P., & Thomas, P. (2023). First light and reionisation epoch simulations (FLARES) – VIII. The emergence of passive galaxies at z ≥ 5. Monthly Notices of the Royal Astronomical Society, 525(4),

The Gaia-ESO Survey: Homogenisation of stellar parameters and elemental abundances (2023)
Journal Article
Hourihane, A., François, P., Worley, C. C., Magrini, L., Gonneau, A., Casey, A. R., Gilmore, G., Randich, S., Sacco, G. G., Recio-Blanco, A., Korn, A. J., Allende Prieto, C., Smiljanic, R., Blomme, R., Bragaglia, A., Walton, N. A., Van Eck, S., Bensby, T., Lanzafame, A., Frasca, A., …Minkevičiūtė, R. (2023). The Gaia-ESO Survey: Homogenisation of stellar parameters and elemental abundances. Astronomy & Astrophysics, 676, Article A129. https://doi.org/10.1051/0004-6361/202345910

The Gaia-ESO Survey is a public spectroscopic survey that targeted greater than or similar to 10(5) stars covering all major components of the Milky Way from the end of 2011 to 2018, delivering its final public release in May 2022. Unlike other spect... Read More about The Gaia-ESO Survey: Homogenisation of stellar parameters and elemental abundances.

RetroBioCat Database: A Platform for Collaborative Curation and Automated Meta-Analysis of Biocatalysis Data (2023)
Journal Article
Finnigan, W., Lubberink, M., Hepworth, L. J., Citoler, J., Mattey, A. P., Ford, G. J., Sangster, J., Cosgrove, S. C., da Costa, B. Z., Heath, R. S., Thorpe, T. W., Yu, Y., Flitsch, S. L., & Turner, N. J. (2023). RetroBioCat Database: A Platform for Collaborative Curation and Automated Meta-Analysis of Biocatalysis Data. ACS catalysis, 13(17), 11771-11780. https://doi.org/10.1021/acscatal.3c01418

Despite the increasing use of biocatalysis for organic synthesis, there are currently no databases that adequately capture synthetic biotransformations. The lack of a biocatalysis database prevents accelerating biocatalyst characterization efforts fr... Read More about RetroBioCat Database: A Platform for Collaborative Curation and Automated Meta-Analysis of Biocatalysis Data.

Coherent Phonons in van der Waals MoSe2/WSe2 Heterobilayers (2023)
Journal Article
Li, C., Scherbakov, A. V., Soubelet, P., Samusev, A. K., Ruppert, C., Balakrishnan, N., Gusev, V. E., Stier, A. V., Finley, J. J., Bayer, M., & Akimov, A. V. (2023). Coherent Phonons in van der Waals MoSe2/WSe2 Heterobilayers. Nano Letters, https://doi.org/10.1021/acs.nanolett.3c02316

The increasing role of two-dimensional (2D) devices requires the development of new techniques for ultrafast control of physical properties in 2D van der Waals (vdW) nanolayers. A special feature of heterobilayers assembled from vdW monolayers is fem... Read More about Coherent Phonons in van der Waals MoSe2/WSe2 Heterobilayers.

Reduced order modelling using neural networks for predictive modelling of 3d-magneto-mechanical problems with application to magnetic resonance imaging scanners (2023)
Journal Article
Miah, S., Sooriyakanthan, Y., Ledger, P. D., Gil, A. J., & Mallett, M. (2023). Reduced order modelling using neural networks for predictive modelling of 3d-magneto-mechanical problems with application to magnetic resonance imaging scanners. Engineering with Computers, 39(6), 4103-4127. https://doi.org/10.1007/s00366-023-01870-3

The design of magnets for magnetic resonance imaging (MRI) scanners requires the numerical simulation of a coupled magneto-mechanical system where the effects that different material parameters and in-service loading conditions have on both imaging a... Read More about Reduced order modelling using neural networks for predictive modelling of 3d-magneto-mechanical problems with application to magnetic resonance imaging scanners.

First light and reionization epoch simulations (FLARES) X iii: the lyman-continuum emission of high-redshift galaxies (2023)
Journal Article
Seeyave, L. T. C., Wilkins, S. M., Kuusisto, J. K., Lovell, C. C., Irodotou, D., Simmonds, C., Vijayan, A. P., Thomas, P. A., Roper, W. J., Byrne, C. M., Jones, G. T., Turner, J. C., & Conselice, C. J. (2023). First light and reionization epoch simulations (FLARES) X iii: the lyman-continuum emission of high-redshift galaxies. Monthly Notices of the Royal Astronomical Society, 525(2), 2422-2440. https://doi.org/10.1093/mnras/stad2487

Single-cell profiling of mosquito spermatogenesis defines the onset of meiotic silencing and pre-meiotic overexpression of the X chromosome. (2023)
Journal Article
Page, N., Taxiarchi, C., Tonge, D., Kuburic, J., Chesters, E., Kriezis, A., Kyrou, K., Game, L., Nolan, T., & Galizi, R. (in press). Single-cell profiling of mosquito spermatogenesis defines the onset of meiotic silencing and pre-meiotic overexpression of the X chromosome. Communications Biology, 6, Article 850. https://doi.org/10.1038/s42003-023-05224-z

Understanding development and genetic regulation in the Anopheles gambiae germline is essential to engineer effective genetic control strategies targeting this malaria mosquito vector. These include targeting the germline to induce sterility or using... Read More about Single-cell profiling of mosquito spermatogenesis defines the onset of meiotic silencing and pre-meiotic overexpression of the X chromosome..

Single-cell profiling of Anopheles gambiae spermatogenesis defines the onset of meiotic silencing and premeiotic overexpression of the X chromosome (2023)
Journal Article
Page, N., Taxiarchi, C., Tonge, D., Kuburic, J., Chesters, E., Kriezis, A., Game, L., Kyrou, K., Game, L., Nolan, T., & Galizi, R. (2023). Single-cell profiling of Anopheles gambiae spermatogenesis defines the onset of meiotic silencing and premeiotic overexpression of the X chromosome. Communications Biology, 6(1), Article 850. https://doi.org/10.1038/s42003-023-05224-z

Understanding development and genetic regulation in the Anopheles gambiae germline is essential to engineer effective genetic control strategies targeting this malaria mosquito vector. These include targeting the germline to induce sterility or using... Read More about Single-cell profiling of Anopheles gambiae spermatogenesis defines the onset of meiotic silencing and premeiotic overexpression of the X chromosome.

Identification and characterization of two CRISPR-Cas systems associated with the mosquito microbiome (2023)
Journal Article
Hegde, S., Rauch, H. E., Hughes, G. L., & Shariat, N. (in press). Identification and characterization of two CRISPR-Cas systems associated with the mosquito microbiome. Access Microbiology, 5(8), https://doi.org/10.1099/acmi.0.000599.v3

The microbiome profoundly influences many traits in medically relevant vectors such as mosquitoes, and a greater functional understanding of host-microbe interactions may be exploited for novel microbial-based approaches to control mosquito-borne dis... Read More about Identification and characterization of two CRISPR-Cas systems associated with the mosquito microbiome.

Probing magnetization dynamics of iron oxide nanoparticles using a point-probe magneto-optical method (2023)
Journal Article
Wang, X., Cabrera, D., Yang, Y., & Telling, N. (in press). Probing magnetization dynamics of iron oxide nanoparticles using a point-probe magneto-optical method. Frontiers in Nanotechnology, 5, Article 1214313. https://doi.org/10.3389/fnano.2023.1214313

Magnetic nanoparticles (MNPs) are promising as local heat generators for magnetic hyperthermia under AC magnetic fields. The heating efficacy of MNPs is determined by the AC hysteresis loop area, which in turn is affected by the dynamic magnetic prop... Read More about Probing magnetization dynamics of iron oxide nanoparticles using a point-probe magneto-optical method.