Skip to main content

Research Repository

Advanced Search

All Outputs (1775)

Prostate cancer risk: associations with ultraviolet radiation, tyrosinase and melanocortin-1 receptor genotypes (2001)
Journal Article
Luscombe, C. J., French, M. E., Liu, S., Saxby, M. F., Jones, P. W., Fryer, A. A., & Strange, R. C. (2001). Prostate cancer risk: associations with ultraviolet radiation, tyrosinase and melanocortin-1 receptor genotypes. British journal of cancer, 85, 1504 - 1509. https://doi.org/10.1054/bjoc.2001.2097

Exposure to ultraviolet radiation may reduce prostate cancer risk, suggesting that polymorphism in genes that mediate host pigmentation will be associated with susceptibility to this cancer. We studied 210 prostate cancer cases and 155 controls to de... Read More about Prostate cancer risk: associations with ultraviolet radiation, tyrosinase and melanocortin-1 receptor genotypes.

Role of crystallographic structure on magnetization reversal of (101̄0) and (112̄0) textured thin film media (2001)
Journal Article
Holloway, L., Laidler, H., Telling, N. D., & Wu, S. Z. (2001). Role of crystallographic structure on magnetization reversal of (101̄0) and (112̄0) textured thin film media. Journal of Applied Physics, 90(8), 4056-4062. https://doi.org/10.1063/1.1400101

In this study we examine the role of crystallographic structure on the magnetization reversal of two CoCrPtTa thin films grown on different underlayers which provide either a [112̄0] or a [101̄0] preferred orientation. We report synchrotron x-ray mea... Read More about Role of crystallographic structure on magnetization reversal of (101̄0) and (112̄0) textured thin film media.

Preparation of short-period Fe-N magnetic multilayers using an atomic nitrogen beam (2001)
Journal Article
Telling, N., Bonder, M., Jones, G., Faunce, C., Grundy, P., Lord, D., & Joyce, D. (2001). Preparation of short-period Fe-N magnetic multilayers using an atomic nitrogen beam. IEEE Transactions on Magnetics, 37(4), 2308-2310. https://doi.org/10.1109/20.951156

Magnetic multilayers containing Fe-N layers with bilayer periods of between /spl sim/15-84 /spl Aring/ and sharp interfaces, are successfully grown using an atomic (free radical) nitrogen beam. The phase composition and microstructure is found to be... Read More about Preparation of short-period Fe-N magnetic multilayers using an atomic nitrogen beam.

Simultaneous identification of GSTP1 Ile105-->Val105 and Ala114-->Val114 substitutions using an amplification refractory mutation system polymerase chain reaction assay: studies in patients with asthma (2001)
Journal Article
Hemmingsen, A., Fryer, A. A., Hepple, M., Strange, R. C., & Spiteri, M. A. (2001). Simultaneous identification of GSTP1 Ile105-->Val105 and Ala114-->Val114 substitutions using an amplification refractory mutation system polymerase chain reaction assay: studies in patients with asthma. Respiratory Research, 255 -260. https://doi.org/10.1186/rr64

BACKGROUND The glutathione S-transferase (GST) enzyme GSTP1 utilizes byproducts of oxidative stress. We previously showed that alleles of GSTP1 that encode the Ile105-->Val105 substitution are associated with the asthma phenotypes of atopy and bronc... Read More about Simultaneous identification of GSTP1 Ile105-->Val105 and Ala114-->Val114 substitutions using an amplification refractory mutation system polymerase chain reaction assay: studies in patients with asthma.

Interdiffusion in direct ion beam deposited isotopic Fe/Si trilayers (2001)
Journal Article
Telling, N. D., Faunce, C. A., Bonder, M. J., Grundy, P. J., Lord, D. G., Van den Berg, J. A., & Langridge, S. (2001). Interdiffusion in direct ion beam deposited isotopic Fe/Si trilayers. Journal of Applied Physics, 89(11), 7074-7076. https://doi.org/10.1063/1.1357151

Interdiffusion and intermixing have been examined in Fe/Si trilayers prepared with ions of different energies, using the direct ion beam deposition technique. Isotope-pure layers were deposited and spin-polarized neutron reflectivity used to determin... Read More about Interdiffusion in direct ion beam deposited isotopic Fe/Si trilayers.

Fe–N alloy films prepared using a nitrogen atom source (2001)
Journal Article
Telling, N., Jones, G., Grundy, P., & Blythe, H. (2001). Fe–N alloy films prepared using a nitrogen atom source. Journal of Magnetism and Magnetic Materials, 226-230, 1659-1661. https://doi.org/10.1016/s0304-8853%2800%2901103-3

We have studied the magnetic and structural properties of Fe–N alloy films prepared by magnetron sputtering in the presence of a highly reactive beam of atomic nitrogen. The nitrogen content was varied by altering the exposure time of the growing fil... Read More about Fe–N alloy films prepared using a nitrogen atom source.

Microstructure of Fe–N thin films prepared using an atomic nitrogen beam (2001)
Journal Article
Telling, N. D., Jones, G. A., Faunce, C. A., Grundy, P. J., Blythe, H. J., & Joyce, D. E. (2001). Microstructure of Fe–N thin films prepared using an atomic nitrogen beam. Journal of Vacuum Science and Technology A, 19(2), 405-409. https://doi.org/10.1116/1.1339016

The formation of Fe–N thin films by exposure to an atomic (free radical) nitrogen beam is reported. This new method of preparing Fe–N films uses fluxes of highly reactive, thermal energy N atoms that do not disturb the film microstructure. It is show... Read More about Microstructure of Fe–N thin films prepared using an atomic nitrogen beam.

The influence of HLA-DRB1 alleles encoding the DERAA amino acid motif on radiological outcome in rheumatoid arthritis. (1999)
Journal Article
(1999). The influence of HLA-DRB1 alleles encoding the DERAA amino acid motif on radiological outcome in rheumatoid arthritis. Rheumatology, 1221 - 1227. https://doi.org/10.1093/rheumatology/38.12.1221

To investigate the influence of HLA-DRB1 alleles encoding the QK/RRAA shared epitope (SE) on radiological outcome in rheumatoid arthritis (RA), and to determine whether it is modulated by alleles carrying the putative rheumatoid arthritis-protective... Read More about The influence of HLA-DRB1 alleles encoding the DERAA amino acid motif on radiological outcome in rheumatoid arthritis..

Expression and subcellular localization of cyclin D1 protein in epithelial ovarian tumour cells (1999)
Journal Article
Dhar, K. K., Branigan, K., Parkes, J., Howells, R. E. J., Hand, P., Musgrove, C., …Hoban, P. R. (1999). Expression and subcellular localization of cyclin D1 protein in epithelial ovarian tumour cells. British journal of cancer, 81, 1174 -1181. https://doi.org/10.1038/sj.bjc.6690826

The expression of cyclin D1 protein in tumour sections from 81 patients with epithelial ovarian cancer was analysed using immunohistochemistry. The tumours that overexpressed cyclin D1 in more than 10% of neoplastic cells were considered positive. Th... Read More about Expression and subcellular localization of cyclin D1 protein in epithelial ovarian tumour cells.

Spin polarised neutron and X-ray reflectivity study of a Co/Cu multilayer deposited under ion bombardment (1999)
Journal Article
Telling, N., Langridge, S., & Tang, C. (1999). Spin polarised neutron and X-ray reflectivity study of a Co/Cu multilayer deposited under ion bombardment. Journal of Magnetism and Magnetic Materials, 198-199, 692-694. https://doi.org/10.1016/s0304-8853%2898%2901204-9

Spin polarised neutron reflectivity and X-ray reflectivity measurements were performed on a Co/Cu multilayer deposited under ion bombardment. It was found that an average ion energy of ∼200 eV caused a reduction in interface roughness towards the sur... Read More about Spin polarised neutron and X-ray reflectivity study of a Co/Cu multilayer deposited under ion bombardment.

The effect of energetic ion bombardment during growth on the interface structure of Co/Cu multilayers (1999)
Journal Article
Telling, N., Karlsson, C., Crapper, M., & Tang, C. (1999). The effect of energetic ion bombardment during growth on the interface structure of Co/Cu multilayers. Journal of Magnetism and Magnetic Materials, 198-199, 713-715. https://doi.org/10.1016/s0304-8853%2898%2901015-4

A modified unbalanced magnetron sputtering technique was applied to the growth of multilayer Co/Cu films in order to systematically study the interface structure evolved under ion bombardment. X-ray reflectivity measurements revealed an interface smo... Read More about The effect of energetic ion bombardment during growth on the interface structure of Co/Cu multilayers.

Reflectivity and diffraction study of Co/Cu multilayer using synchrotron X-rays (1999)
Journal Article
Tang, C., MacLean, E., & Telling, N. (1999). Reflectivity and diffraction study of Co/Cu multilayer using synchrotron X-rays. Journal of Magnetism and Magnetic Materials, 198-199, 653-655. https://doi.org/10.1016/s0304-8853%2898%2901176-7

Synchrotron powder diffraction measurements were obtained from a Co/Cu multilayer produced by low energy ion-assisted deposition. The experiment was carried out on the high resolution diffractometer on Station 2.3 at the SRS, Daresbury Laboratory. Ex... Read More about Reflectivity and diffraction study of Co/Cu multilayer using synchrotron X-rays.

Multilayer growth by low energy ion beam deposition (1999)
Journal Article
Joyce, D., Telling, N., Van den Berg, J., Lord, D., & Grundy, P. (1999). Multilayer growth by low energy ion beam deposition. Journal of Magnetism and Magnetic Materials, 198-199, 731-733. https://doi.org/10.1016/s0304-8853%2898%2901021-x

We report our progress in the development of a relatively new deposition technique, that of direct low energy ion beam deposition. We describe this technique, which is based on ion implanter technology similar to that used in the semiconductor indust... Read More about Multilayer growth by low energy ion beam deposition.

The therapeutic response to D-penicillamine in rheumatoid arthritis: influence of glutathione S-transferase polymorphisms (1999)
Journal Article
Layton, M. A., Jones, P. W., Alldersea, J. E., Strange, R. C., Fryer, A. A., Dawes, P. T., & Mattey, D. L. (1999). The therapeutic response to D-penicillamine in rheumatoid arthritis: influence of glutathione S-transferase polymorphisms. Rheumatology, 38(1), 43 - 47. https://doi.org/10.1093/rheumatology/38.1.43

To investigate whether the therapeutic response of rheumatoid arthritis (RA) patients to D-penicillamine is associated with polymorphisms in genes of the glutathione S-transferase (GST) supergene family.

Influence of polymorphisms at glutathione-S-transferase gene loci on allelic losses in head and neck squamous cell carcinomas,Einfluss yon genpolymorphismen in den entgiftenden enzymen der glutathion-S-transferasen auf die chromosomale stabilitat yon plattenepithelkarzinomen im kopf-hals-bereich (1998)
Journal Article
Matthias, C., Bockmühl, U., Jahnke, V., Petersen, I., Dietel, M., Fryer, A., & Strange, R. (1998). Influence of polymorphisms at glutathione-S-transferase gene loci on allelic losses in head and neck squamous cell carcinomas,Einfluss yon genpolymorphismen in den entgiftenden enzymen der glutathion-S-transferasen auf die chromosomale stabilitat yon plattenepithelkarzinomen im kopf-hals-bereich. Laryngo-Rhino-Otologie, 77(4), 201-206. https://doi.org/10.1055/s-2007-996961

Background: While cigarette smoking and chronic alcohol consumption are the major risk factors for the development of head and neck cancer, it is assumed that genetic factors contribute to risk. Material and methods: We examined genotype frequencies... Read More about Influence of polymorphisms at glutathione-S-transferase gene loci on allelic losses in head and neck squamous cell carcinomas,Einfluss yon genpolymorphismen in den entgiftenden enzymen der glutathion-S-transferasen auf die chromosomale stabilitat yon plattenepithelkarzinomen im kopf-hals-bereich.

Synchrotron X-ray reflectivity study of Co/Cu multilayer structure (1998)
Journal Article
Tang, C., Telling, N., & Langridge, S. (1998). Synchrotron X-ray reflectivity study of Co/Cu multilayer structure. Physica B: Condensed Matter, 248(1-4), 395-398. https://doi.org/10.1016/s0921-4526%2898%2900270-1

We report on the use of Station 2.3 at the SRS Daresbury Laboratory as a high resolution reflectivity diffractometer (HRRD) for the study of interfacial structure in a Co/Cu multilayer grown using the ion-assisted deposition method. Specular, off-spe... Read More about Synchrotron X-ray reflectivity study of Co/Cu multilayer structure.

Microstructural modification in Co/Cu multilayers prepared by low energy ion-assisted deposition (1998)
Journal Article
Telling, N., Crapper, M., Lovett, D., Guilfoyle, S., Tang, C., & Petty, M. (1998). Microstructural modification in Co/Cu multilayers prepared by low energy ion-assisted deposition. Thin Solid Films, 317(1-2), 278-281. https://doi.org/10.1016/s0040-6090%2897%2900537-3

The microstructure of Co/Cu multilayers deposited by low energy ion-assisted deposition was investigated. The samples studied were grown by unbalanced magnetron sputtering with and without an applied d.c. substrate bias of −50 V. Specular and off-spe... Read More about Microstructural modification in Co/Cu multilayers prepared by low energy ion-assisted deposition.