Latent gammaherpesvirus infection enhances type I IFN response and reduces virus spread in an influenza A virus co-infection model. (2024)
Journal Article
Hardisty, G., Nicol, M. Q., Shaw, D. J., Bennet, I. D., Bryson, K., Ligertwood, Y., …Dutia, B. M. (2024). Latent gammaherpesvirus infection enhances type I IFN response and reduces virus spread in an influenza A virus co-infection model. Journal of General Virology, 105(2), https://doi.org/10.1099/jgv.0.001962

Infections with persistent or latent viruses alter host immune homeostasis and have potential to affect the outcome of concomitant acute viral infections such as influenza A virus (IAV). Gammaherpesviruses establish life-long infections and require a... Read More about Latent gammaherpesvirus infection enhances type I IFN response and reduces virus spread in an influenza A virus co-infection model..

Constraining the reflective properties of WASP-178 b using CHEOPS photometry (2024)
Journal Article
Pagano, I., Scandariato, G., Singh, V., Lendl, M., Queloz, D., Simon, A. E., …Walton, N. A. (2024). Constraining the reflective properties of WASP-178 b using CHEOPS photometry. Astronomy & Astrophysics, 682, Article A102. https://doi.org/10.1051/0004-6361/202346705

Context. Multiwavelength photometry of the secondary eclipses of extrasolar planets is able to disentangle the reflected and thermally emitted light radiated from the planetary dayside. Based on this, we can measure the planetary geometric albedo Ag,... Read More about Constraining the reflective properties of WASP-178 b using CHEOPS photometry.

Characterising TOI-732 b and c: New insights into the M-dwarf radius and density valley (2024)
Journal Article
Bonfanti, A., Brady, M., Wilson, T. G., Venturini, J., Egger, J. A., Brandeker, A., …Zingales, T. (2024). Characterising TOI-732 b and c: New insights into the M-dwarf radius and density valley. Astronomy & Astrophysics, 682, Article A66. https://doi.org/10.1051/0004-6361/202348180

Context. TOI-732 is an M dwarf hosting two transiting planets that are located on the two opposite sides of the radius valley. Inferring a reliable demographics for this type of systems is key to understanding their formation and evolution mechanisms... Read More about Characterising TOI-732 b and c: New insights into the M-dwarf radius and density valley.

Optical Microscopy Using the Faraday Effect Reveals in Situ Magnetization Dynamics of Magnetic Nanoparticles in Biological Samples (2024)
Journal Article
Sharifabad, M. E., Eizadi Sharifabad, M., Soucaille, R., Wang, X., Rotherham, M., Loughran, T., …Telling, N. (2024). Optical Microscopy Using the Faraday Effect Reveals in Situ Magnetization Dynamics of Magnetic Nanoparticles in Biological Samples. ACS Nano, 18(7), 5297-5310. https://doi.org/10.1021/acsnano.3c08955

The study of exogenous and endogenous nanoscale magnetic material in biology is important for developing biomedical nanotechnology as well as for understanding fundamental biological processes such as iron metabolism and biomineralization. Here, we e... Read More about Optical Microscopy Using the Faraday Effect Reveals in Situ Magnetization Dynamics of Magnetic Nanoparticles in Biological Samples.

Sources of prey availability data alter interpretation of outputs from prey choice null networks (2024)
Journal Article
Cuff, J. P., Tercel, M. P., Windsor, F. M., Hawthorne, B. S., Hambäck, P. A., Bell, J. R., …Vaughan, I. P. (2024). Sources of prey availability data alter interpretation of outputs from prey choice null networks. Ecological Entomology, https://doi.org/10.1111/een.13315

Null models provide a valuable baseline against which fundamental ecological hypotheses can be tested and foraging choices that cannot be explained by neutral processes or sampling biases can be highlighted. In this way, null models can advance our u... Read More about Sources of prey availability data alter interpretation of outputs from prey choice null networks.

A Galactic Eclipse: The Small Magellanic Cloud Is Forming Stars in Two Superimposed Systems (2024)
Journal Article
Murray, C. E., Hasselquist, S., Peek, J. E. G., Lindberg, C. W., Almeida, A., Choi, Y., …van Loon, J. T. (2024). A Galactic Eclipse: The Small Magellanic Cloud Is Forming Stars in Two Superimposed Systems. Astrophysical Journal, 962(2), Article 120. https://doi.org/10.3847/1538-4357/ad1591

The structure and dynamics of the star-forming disk of the Small Magellanic Cloud (SMC) have long confounded us. The SMC is widely used as a prototype for galactic physics at low metallicity, and yet we fundamentally lack an understanding of the stru... Read More about A Galactic Eclipse: The Small Magellanic Cloud Is Forming Stars in Two Superimposed Systems.

Decellularisation and Characterisation of Porcine Pleura as Bioscaffolds in Tissue Engineering (2024)
Journal Article
Vikranth, T., Dale, T., & Forsyth, N. R. (2024). Decellularisation and Characterisation of Porcine Pleura as Bioscaffolds in Tissue Engineering. Journal of Tissue Engineering and Regenerative Medicine, https://doi.org/10.1155/2024/9940673

Persistent air leaks caused by thoracic surgery, physical trauma, or spontaneous pneumothoraces are a cause of patient morbidity with need for extended chest tube durations and surgical interventions. Current treatment measures involve mechanical clo... Read More about Decellularisation and Characterisation of Porcine Pleura as Bioscaffolds in Tissue Engineering.

Using healthcare systems data for outcomes in clinical trials: issues to consider at the design stage (2024)
Journal Article
Toader, A.-M., Campbell, M. K., Quint, J. K., Robling, M., ydes, M. R., Thorn, J., …Williamson, P. (2024). Using healthcare systems data for outcomes in clinical trials: issues to consider at the design stage. Trials, 25(1), https://doi.org/10.1186/s13063-024-07926-z

Background
Healthcare system data (HSD) are increasingly used in clinical trials, augmenting or replacing traditional methods of collecting outcome data. This study, PRIMORANT, set out to identify, in the UK context, issues to be considered before t... Read More about Using healthcare systems data for outcomes in clinical trials: issues to consider at the design stage.

Transgenic expression of cif genes from Wolbachia strain wAlbB recapitulates cytoplasmic incompatibility in Aedes aegypti (2024)
Journal Article
McNamara, C. J., Ant, T. H., Harvey-Samuel, T., White-Cooper, H., Martinez, J., Alphey, L., & Sinkins, S. P. (in press). Transgenic expression of cif genes from Wolbachia strain wAlbB recapitulates cytoplasmic incompatibility in Aedes aegypti. Nature communications, 15(1), Article 869. https://doi.org/10.1038/s41467-024-45238-7

The endosymbiotic bacteria Wolbachia can invade insect populations by modifying host reproduction through cytoplasmic incompatibility (CI), an effect that results in embryonic lethality when Wolbachia-carrying males mate with Wolbachia-free females.... Read More about Transgenic expression of cif genes from Wolbachia strain wAlbB recapitulates cytoplasmic incompatibility in Aedes aegypti.

A multiplexed, confinable CRISPR/Cas9 gene drive can propagate in caged Aedes aegypti populations (2024)
Journal Article
Anderson, M. A. E., Gonzalez, E., Edgington, M. P., Ang, J. X. D., Purusothaman, D.-K., Shackleford, L., …Alphey, L. (in press). A multiplexed, confinable CRISPR/Cas9 gene drive can propagate in caged Aedes aegypti populations. Nature communications, 15(1), Article 729. https://doi.org/10.1038/s41467-024-44956-2

Aedes aegypti is the main vector of several major pathogens including dengue, Zika and chikungunya viruses. Classical mosquito control strategies utilizing insecticides are threatened by rising resistance. This has stimulated interest in new genetic... Read More about A multiplexed, confinable CRISPR/Cas9 gene drive can propagate in caged Aedes aegypti populations.

Synthesis of a heparan sulfate tetrasaccharide using automated glycan assembly † (2024)
Journal Article
Pongener, I., Sletten, E. T., Danglad-Flores, J., Seeberger, P. H., & Miller, G. J. (in press). Synthesis of a heparan sulfate tetrasaccharide using automated glycan assembly †. Organic and Biomolecular Chemistry, https://doi.org/10.1039/d3ob01909h

Herein we utilise automated glycan assembly to complete solid-phase synthesis of defined heparan sulfate oligosaccharides, employing challenging d-glucuronate disaccharide donors. Using an orthogonally protected d-GlcN-α-d-GlcA donor, milligram-scale... Read More about Synthesis of a heparan sulfate tetrasaccharide using automated glycan assembly †.

Responding to misrepresentation: Sample pack creation, branding and distribution (2024)
Journal Article
Blackburn, M. (2024). Responding to misrepresentation: Sample pack creation, branding and distribution. Sound Studies, 1-31. https://doi.org/10.1080/20551940.2023.2301214

This article documents the creation and distribution of a new sample pack, Instruments INDIA, as an intervention against systemic orientalist practices observable within the marketing, branding and production of non-Western instrument sample packs. T... Read More about Responding to misrepresentation: Sample pack creation, branding and distribution.

Identification of a non-exported Plasmepsin V substrate that functions in the parasitophorous vacuole of malaria parasites (2024)
Journal Article
Fréville, A., Ressurreição, M., & van Ooij, C. (2024). Identification of a non-exported Plasmepsin V substrate that functions in the parasitophorous vacuole of malaria parasites. mBio, 15(1), https://doi.org/10.1128/mbio.01223-23

Malaria parasites alter multiple properties of the host erythrocyte by exporting proteins into the host cell. Many exported proteins contain a five-amino acid motif called the Plasmodium export element (PEXEL) that is cleaved by the parasite protease... Read More about Identification of a non-exported Plasmepsin V substrate that functions in the parasitophorous vacuole of malaria parasites.

Giant offshore pumice deposit records a shallow submarine explosive eruption of ancestral Santorini (2024)
Journal Article
Druitt, T., Kutterolf, S., Ronge, T. A., Hübscher, C., Nomikou, P., Preine, J., …Lee, H. (2024). Giant offshore pumice deposit records a shallow submarine explosive eruption of ancestral Santorini. Communications Earth & Environment, 5(1), Article 24. https://doi.org/10.1038/s43247-023-01171-z

Large explosive volcanic eruptions from island arcs pour pyroclastic currents into marine basins, impacting ecosystems and generating tsunamis that threaten coastal communities and infrastructures. Risk assessments require robust records of such high... Read More about Giant offshore pumice deposit records a shallow submarine explosive eruption of ancestral Santorini.

Bricks, brick-making, and the economies of the Old Poor Law: Staffordshire 1750-1834 (2024)
Journal Article
Tomkins, A. (in press). Bricks, brick-making, and the economies of the Old Poor Law: Staffordshire 1750-1834. Midland History, 1-20. https://doi.org/10.1080/0047729x.2024.2303645

This article considers the place of brickmaking as an activity supported or promoted by parish poor relief. Parochial work schemes were typically founded on agricultural work, textile manufacturing, or unskilled tasks like oakum picking, yet the man... Read More about Bricks, brick-making, and the economies of the Old Poor Law: Staffordshire 1750-1834.

Aedes aegypti gut transcriptomes respond differently to microbiome transplants from field‐caught or laboratory‐reared mosquitoes (2024)
Journal Article
Hegde, S., Brettell, L. E., Quek, S., Etebari, K., Saldaña, M. A., Asgari, S., …Hughes, G. L. (2024). Aedes aegypti gut transcriptomes respond differently to microbiome transplants from field‐caught or laboratory‐reared mosquitoes. Environmental Microbiology, 26(2), Article e16576. https://doi.org/10.1111/1462-2920.16576

The mosquito microbiome is critical for host development and plays a major role in many aspects of mosquito biology. While the microbiome is commonly dominated by a small number of genera, there is considerable variation in composition among mosquito... Read More about Aedes aegypti gut transcriptomes respond differently to microbiome transplants from field‐caught or laboratory‐reared mosquitoes.

The Colombo Twin and Singleton Study (COTASS): Piloting the Feasibility of Collecting Nutritional Data and Extension of the Sample to Include Children of Twins. (2024)
Journal Article
Dissanayake, L., Herath, B., Opatha, J., Jabir, S., Siriwardana, R., Sirisena, K., …Rijsdijk, F. (in press). The Colombo Twin and Singleton Study (COTASS): Piloting the Feasibility of Collecting Nutritional Data and Extension of the Sample to Include Children of Twins. Behavior Genetics, 54(1), 63–72. https://doi.org/10.1007/s10519-023-10171-w

Nutrition and diet are key modifiable risk factors for the rising burden of non-communicable diseases like cardio-vascular diseases and diabetes in low- and middle- income countries (LMICs). The nutritional transition in dietary behaviours in LMICs h... Read More about The Colombo Twin and Singleton Study (COTASS): Piloting the Feasibility of Collecting Nutritional Data and Extension of the Sample to Include Children of Twins..

Impact of the COVID-19 pandemic on young people living with HIV in Lesotho: a qualitative study (2024)
Journal Article
Shepherd, T., Robinson, M. E., Ramaema, M., Rakuoane, M., Moletsane, N., Mpholo, R., …Leigh, G. (2024). Impact of the COVID-19 pandemic on young people living with HIV in Lesotho: a qualitative study. BMJ Public Health, 2(1), Article e000414. https://doi.org/10.1136/bmjph-2023-000414

Introduction: There is a growing body of research evidencing the detrimental impact of the COVID-19 pandemic on the mental health and well-being of young people. This impact may be worse in low-resource settings, especially those in sub-Saharan Afric... Read More about Impact of the COVID-19 pandemic on young people living with HIV in Lesotho: a qualitative study.

The impact of mental health and psychosocial support programmes on children and young people's mental health in the context of humanitarian emergencies in low- and middle-income countries: A systematic review and meta-analysis. (2024)
Journal Article
Bangpan, M., Felix, L., Soliman, F., D'Souza, P., Jieman, A., & Dickson, K. (2024). The impact of mental health and psychosocial support programmes on children and young people's mental health in the context of humanitarian emergencies in low- and middle-income countries: A systematic review and meta-analysis. Global Mental Health, 11, Article e21. https://doi.org/10.1017/gmh.2024.17

Humanitarian emergencies pose a significant global health challenge for children and young people's mental and psychological health. This systematic review investigates the effectiveness of mental health and psychosocial support (MHPSS) programmes de... Read More about The impact of mental health and psychosocial support programmes on children and young people's mental health in the context of humanitarian emergencies in low- and middle-income countries: A systematic review and meta-analysis..

Putting the Spotlight Back Onto the Flanker Task in Autism: Autistic Adults Show Increased Interference from Foils Compared with Non-autistic Adults. (2024)
Journal Article
Poole, D., Grange, J. A., & Milne, E. (2024). Putting the Spotlight Back Onto the Flanker Task in Autism: Autistic Adults Show Increased Interference from Foils Compared with Non-autistic Adults. Journal of Cognition, 7(1), 46. https://doi.org/10.5334/joc.369

Autistic people may have a less focused spotlight of spatial selective attention than non-autistic people, meaning that distracting stimuli are less effectively suppressed. Previous studies using the flanker task have supported this suggestion with o... Read More about Putting the Spotlight Back Onto the Flanker Task in Autism: Autistic Adults Show Increased Interference from Foils Compared with Non-autistic Adults..