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Outputs (352)

A qualitative exploration of the barriers and facilitators to self‐managing multiple long‐term conditions amongst people experiencing socioeconomic deprivation (2024)
Journal Article

Background: Globally, it is estimated that one in three adults live with two or more long‐term conditions (multiple long‐term conditions, MLTCs), that require self‐management. People who experience socioeconomic deprivation face significant health in... Read More about A qualitative exploration of the barriers and facilitators to self‐managing multiple long‐term conditions amongst people experiencing socioeconomic deprivation.

Filling in the gaps: A grounded theory of the experiences and needs of healthcare staff following a colleague death by suicide in the UK. (2024)
Journal Article

Health-workers are more likely to die by suicide than their counterparts in other occupational groups. The suicide of a staff member can be widely felt by colleagues, leading to complex emotional and cognitive responses. Exposure to suicide heightens... Read More about Filling in the gaps: A grounded theory of the experiences and needs of healthcare staff following a colleague death by suicide in the UK..

Distinguishing emotional distress from mental disorder: A qualitative exploration of the Four-Dimensional Symptom Questionnaire (4DSQ). (2024)
Journal Article

Primary care clinicians see people experiencing the full range of mental health problems. Determining when symptoms reflect disorder is complex. The Four-Dimensional Symptom Questionnaire (4DSQ) uniquely distinguishes general distress from depressive... Read More about Distinguishing emotional distress from mental disorder: A qualitative exploration of the Four-Dimensional Symptom Questionnaire (4DSQ)..

Collaboration across the primary/specialist interface in early intervention in psychosis services: a qualitative study (2024)
Journal Article

Background People with new psychotic symptoms may be managed within an Early Intervention in Psychosis service (EIP). They may be discharged back to primary care at the end of their time in an EIP service. Aim To explore the role of primary care in s... Read More about Collaboration across the primary/specialist interface in early intervention in psychosis services: a qualitative study.

Accessing care for Long Covid from the perspectives of patients and healthcare practitioners: A qualitative study (2024)
Journal Article

Background: Long Covid is an emerging long‐term condition, with those affected raising concerns about lack of healthcare support. Objective: We conducted a qualitative study to identify facilitators and barriers to healthcare access for people with L... Read More about Accessing care for Long Covid from the perspectives of patients and healthcare practitioners: A qualitative study.

Young people's priorities for the self‐management of distress after stoma surgery due to inflammatory bowel disease: A consensus study using online nominal group technique (2024)
Journal Article

Introduction The aim of this study was to gain consensus among young people with a stoma due to inflammatory bowel disease (IBD) on the priorities for the content of an intervention for the self-management of stoma-related distress. The current iden... Read More about Young people's priorities for the self‐management of distress after stoma surgery due to inflammatory bowel disease: A consensus study using online nominal group technique.

Identifying prior signals of bipolar disorder using primary care electronic health records: a nested case-control study. (2024)
Journal Article

Bipolar disorders are serious mental illnesses, yet evidence suggests that the diagnosis and treatment of bipolar disorder can be delayed by around 6 years. To identify signals of undiagnosed bipolar disorder using routinely collected electronic heal... Read More about Identifying prior signals of bipolar disorder using primary care electronic health records: a nested case-control study..

Behavioural activation to mitigate the psychological impacts of COVID-19 restrictions on older people in England and Wales (BASIL+): a pragmatic randomised controlled trial. (2024)
Journal Article

Older adults were more likely to be socially isolated during the COVID-19 pandemic, with increased risk of depression and loneliness. We aimed to investigate whether a behavioural activation intervention delivered via telephone could mitigate depress... Read More about Behavioural activation to mitigate the psychological impacts of COVID-19 restrictions on older people in England and Wales (BASIL+): a pragmatic randomised controlled trial..

Community pharmacists' perceptions on managing people with oral health problems—A prioritisation survey (2024)
Journal Article

Background Alternative sources of oral health information are likely to be of benefit to the public, particularly where access to dental services is limited. There is evidence that community pharmacists are willing to advocate for oral health, but i... Read More about Community pharmacists' perceptions on managing people with oral health problems—A prioritisation survey.

Negotiating the postvention situation: A grounded theory of NHS staff experiences when supporting their coworkers following a colleague’s suicide (2024)
Journal Article

Suicide is a leading cause of death. NHS workers, especially female nurses, have heightened vulnerability. Being impacted by a colleague’s suicide can lead to increased suicidality. Postvention refers to support following a suicide. We investigated c... Read More about Negotiating the postvention situation: A grounded theory of NHS staff experiences when supporting their coworkers following a colleague’s suicide.

Clinical effectiveness of treatments for the management of anxiety in community dwelling people living with dementia: a systematic review and meta‐analysis (2023)
Journal Article

Background People living with dementia commonly experience distress or behavioural and psychological symptoms, such as anxiety, which are associated with worse outcomes in this population. Symptoms of anxiety can be challenging to manage, as there i... Read More about Clinical effectiveness of treatments for the management of anxiety in community dwelling people living with dementia: a systematic review and meta‐analysis.

Working conditions, psychological distress and suicidal ideation: cross-sectional survey study of UK junior doctors (2023)
Journal Article

Background Evidence attests a link between junior doctors’ working conditions and psychological distress. Despite increasing concerns around suicidality among junior doctors, little is known about its relationship to their working conditions. Aim... Read More about Working conditions, psychological distress and suicidal ideation: cross-sectional survey study of UK junior doctors.

Healthcare professionals' priorities for training to identify and manage distress experienced by young people with a stoma due to inflammatory bowel disease: a consensus study using online nominal group technique. (2023)
Journal Article

ObjectivesYoung people with a stoma due to inflammatory bowel disease (IBD) commonly experience distress; however, this is not always well managed in clinical settings. More effective support may/is likely to reduce the possibility of individuals exp... Read More about Healthcare professionals' priorities for training to identify and manage distress experienced by young people with a stoma due to inflammatory bowel disease: a consensus study using online nominal group technique..

Development of the Preferred Components for Co-Design in Research Guideline and Checklist: Protocol for a Scoping Review and a Modified Delphi Process. (2023)
Journal Article

Background: There is increasing evidence that co-design can lead to more engaging, acceptable, relevant, feasible, and even effective interventions. However, no guidance is provided on the specific designs and associated methods or methodologies inv... Read More about Development of the Preferred Components for Co-Design in Research Guideline and Checklist: Protocol for a Scoping Review and a Modified Delphi Process..

An economic evaluation of universal and targeted case-finding strategies for identifying antenatal depression: a model-based analysis comparing common case-finding instruments. (2023)
Journal Article

Half of women with depression in the perinatal period are not identified in routine care, and missed cases reflect inequalities in other areas of maternity care. Case finding (screening) for depression in pregnant women may be a cost-effective strate... Read More about An economic evaluation of universal and targeted case-finding strategies for identifying antenatal depression: a model-based analysis comparing common case-finding instruments..

The acceptability and feasibility of conducting a randomised controlled trial to test the effectiveness of a walking intervention for older people with persistent musculoskeletal pain in primary care: A mixed methods evaluation of the iPOPP pilot trial (2023)
Journal Article

Introduction: Persistent musculoskeletal (MSK) pain is associated with physical inactivity in older people. While walking is an acceptable form of physical activity, the effectiveness of walking interventions in this population has yet to be establis... Read More about The acceptability and feasibility of conducting a randomised controlled trial to test the effectiveness of a walking intervention for older people with persistent musculoskeletal pain in primary care: A mixed methods evaluation of the iPOPP pilot trial.

Pharmacists' perspectives on the impact of postgraduate distance learning on their well-being: A qualitative study. (2023)
Journal Article

Introduction: Undertaking postgraduate education is becoming increasingly common among United Kingdom (UK) pharmacists to facilitate career progression. However, whilst there is evidence that postgraduate study can negatively affect well-being (defin... Read More about Pharmacists' perspectives on the impact of postgraduate distance learning on their well-being: A qualitative study..

Effectiveness of self-management interventions for long-term conditions in people experiencing socio-economic deprivation in high-income countries: a systematic review and meta-analysis (2023)
Journal Article

Background Long-term conditions (LTCs) are prevalent in socio-economically deprived populations. Self-management interventions can improve health outcomes, but socio-economically deprived groups have lower participation in them, with potentially lowe... Read More about Effectiveness of self-management interventions for long-term conditions in people experiencing socio-economic deprivation in high-income countries: a systematic review and meta-analysis.

Self‐directed self‐management interventions to prevent or address distress in young people with long‐term physical conditions: A rapid review (2023)
Journal Article

Comorbid distress in adolescents and young adults with physical long-term conditions (LTCs) is common but can be difficult to identify and manage. Self-directed self-management interventions to reduce distress and improve wellbeing may be beneficial.... Read More about Self‐directed self‐management interventions to prevent or address distress in young people with long‐term physical conditions: A rapid review.

A culturally adapted manual-assisted problem-solving intervention (CMAP) for adults with a history of self-harm: a multi-centre randomised controlled trial (2023)
Journal Article

Background Self-harm is an important predictor of a suicide death. Culturally appropriate strategies for the prevention of self-harm and suicide are needed but the evidence is very limited from low- and middle-income countries (LMICs). This study ai... Read More about A culturally adapted manual-assisted problem-solving intervention (CMAP) for adults with a history of self-harm: a multi-centre randomised controlled trial.

Cumulative complexity: a qualitative analysis of patients' experiences of living with heart failure with preserved ejection fraction (2023)
Journal Article

Funding Acknowledgements Type of funding sources: Public Institution(s). Main funding source(s): NIHR, Evelyn Trust, Burdett Trust. Background Multiple investigations have explored the lived experience of heart failure (HF). However, studies have not... Read More about Cumulative complexity: a qualitative analysis of patients' experiences of living with heart failure with preserved ejection fraction.

Health Care Professionals’ Perspectives of Early Intervention in Psychosis Services: A Qualitative Study (2023)
Presentation / Conference

Aims An Early Intervention in Psychosis (EIP) service offers treatment in the community to people with a first episode of psychosis. EIP is meant to be given for three years; after this time, those who are well are discharged to their GP, while thos... Read More about Health Care Professionals’ Perspectives of Early Intervention in Psychosis Services: A Qualitative Study.

Osteoporosis and fracture as risk factors for self-harm and suicide: a systematic review and meta-analysis (2023)
Journal Article

Background: Increase in presentations of self-harm to primary care, a risk factor of suicide, has led to a growing interest in identifying at-risk populations. Aim: To examine whether osteoporosis or fractures are risk factors for self-harm, sui... Read More about Osteoporosis and fracture as risk factors for self-harm and suicide: a systematic review and meta-analysis.

Temporal trends in eating disorder and self-harm incidence rates among adolescents and young adults in the UK in the 2 years since onset of the COVID-19 pandemic: a population-based study. (2023)
Journal Article

Self-harm and eating disorders share multiple risk factors, with onset typically during adolescence or early adulthood. We aimed to examine the incidence rates of these psychopathologies among young people in the UK in the 2 years following onset of... Read More about Temporal trends in eating disorder and self-harm incidence rates among adolescents and young adults in the UK in the 2 years since onset of the COVID-19 pandemic: a population-based study..

EXPERTS II - How are patient and caregiver participation in health and social care shaped by experienced burden of treatment and social inequalities? Protocol for a qualitative synthesis. (2023)
Journal Article

BackgroundThe workload health and social care service users and caregivers take on, and their capacity to do this work is important. It may play a key part in shaping the implementation of innovations in health service delivery and organisation; the... Read More about EXPERTS II - How are patient and caregiver participation in health and social care shaped by experienced burden of treatment and social inequalities? Protocol for a qualitative synthesis..

Exploring the treatment burden of disease modifying anti rheumatic drug monitoring in people with rheumatoid arthritis (2023)
Journal Article

Objectives People with rheumatoid arthritis (RA) taking disease-modifying anti-rheumatic drugs (DMARDs) require safety monitoring to identify potential side-effects. This study aimed to explore patients’ and family members’ perspectives on DMARD moni... Read More about Exploring the treatment burden of disease modifying anti rheumatic drug monitoring in people with rheumatoid arthritis.

AB1595 HOW DO WE PREVENT THE DEVELOPMENT OF MULTIMORBIDITY IN PEOPLE WITH INFLAMMATORY RHEUMATOLOGICAL DISORDERS: A QUALITATIVE INVESTIGATION (2023)
Journal Article

Background: People with inflammatory rheumatological disorders (IRDs) are at high risk of developing multimorbidity, specifically cardiovascular disease (CVD) and mood problems. UK guidelines advocate annual reviews for people with Rheumatoid Arthrit... Read More about AB1595 HOW DO WE PREVENT THE DEVELOPMENT OF MULTIMORBIDITY IN PEOPLE WITH INFLAMMATORY RHEUMATOLOGICAL DISORDERS: A QUALITATIVE INVESTIGATION.

Non-pharmacological interventions for the management of perinatal anxiety in primary care: A meta-review of systematic reviews (2023)
Journal Article

Perinatal anxiety (PNA), anxiety that occurs during pregnancy and/or up to 12 months post-partum, is estimated to affect up to 21% of women, and may impact negatively on mothers, children and their families. The National Institute for Health and Care... Read More about Non-pharmacological interventions for the management of perinatal anxiety in primary care: A meta-review of systematic reviews.

An economic evaluation of targeted case-finding strategies for identifying postnatal depression: A model-based analysis comparing common case-finding instruments (2023)
Journal Article

Background Half of women with postnatal depression (PND) are not identified in routine care. We aimed to estimate the cost-effectiveness of PND case-finding in women with risk factors for PND. Methods A decision tree was developed to represent t... Read More about An economic evaluation of targeted case-finding strategies for identifying postnatal depression: A model-based analysis comparing common case-finding instruments.

Generating EQ-5D-3L health utility scores from the Edinburgh Postnatal Depression Scale: a perinatal mapping study (2023)
Journal Article

Background Perinatal depression (PND) describes depression experienced by parents during pregnancy or in the first year after a baby is born. The EQ-5D instrument (a generic measure of health status) is not often collected in perinatal research, how... Read More about Generating EQ-5D-3L health utility scores from the Edinburgh Postnatal Depression Scale: a perinatal mapping study.

Generating EQ-5D-3L health utility scores from the Edinburgh Postnatal Depression Scale: a perinatal mapping study (2023)
Journal Article

BACKGROUND: Perinatal depression (PND) describes depression experienced by parents during pregnancy or in the first year after a baby is born. The EQ-5D instrument (a generic measure of health status) is not often collected in perinatal research, how... Read More about Generating EQ-5D-3L health utility scores from the Edinburgh Postnatal Depression Scale: a perinatal mapping study.

Constructing therapeutic support and negotiating competing agendas: A discourse analysis of vocational advice provided to individuals who are absent from work due to ill-health (2023)
Journal Article

Work participation is known to benefit people’s overall health and wellbeing, but accessing vocational support during periods of sickness absence to facilitate return-to-work can be challenging for many people. In this study, we explored how vocation... Read More about Constructing therapeutic support and negotiating competing agendas: A discourse analysis of vocational advice provided to individuals who are absent from work due to ill-health.

The experiences of remote consulting for people with chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) and fibromyalgia in primary care (2023)
Presentation / Conference

Background Restrictions due to the COVID-19 pandemic resulted in a sudden shift to a predominantly remote consulting model in primary care from March 2020. Little evidence exists examining the experience of remote consulting for people living with ch... Read More about The experiences of remote consulting for people with chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) and fibromyalgia in primary care.

Association of strong opioids and antibiotics prescribing with GP burnout: a retrospective cross-sectional study (2023)
Journal Article

Background: Prescribing of strong opioids and antibiotics impacts patient safety, yet little is known about the effects GP wellness has on overprescribing of both medications in primary care. Aim: To examine associations between strong opioid and... Read More about Association of strong opioids and antibiotics prescribing with GP burnout: a retrospective cross-sectional study.

Acceptability of a behavioural intervention to mitigate the psychological impacts of COVID-19 restrictions in older people with long-term conditions: a qualitative study. (2023)
Journal Article

Objectives The COVID-19 pandemic heightened the need to address loneliness, social isolation and associated incidence of depression among older adults. Between June and October 2020, the Behavioural Activation in Social IsoLation (BASIL) pilot stud... Read More about Acceptability of a behavioural intervention to mitigate the psychological impacts of COVID-19 restrictions in older people with long-term conditions: a qualitative study..

Symptom patterns and life with post-acute COVID-19 in children aged 8-17: a mixed methods studyprotocol. (2023)
Journal Article

Background: While there is a substantial body of knowledge about acute COVID-19, less is known about long-COVID, where symptoms continue beyond 4 weeks. Aim: To describe longer-term effects of COVID-19 infection in children and young people (CYP)... Read More about Symptom patterns and life with post-acute COVID-19 in children aged 8-17: a mixed methods studyprotocol..

The functions of self-harm in young people and their perspectives about future general practitioner-led care: A qualitative study. (2023)
Journal Article

BACKGROUND: Self-harm in young people is a serious concern but a deeper understanding of the functions of self-harm in young people can tailor care and inform new clinical interventions to reduce repeat self-harm and suicide risk. General practitione... Read More about The functions of self-harm in young people and their perspectives about future general practitioner-led care: A qualitative study..

Self-management of multiple long-term conditions: A systematic review of the barriers and facilitators amongst people experiencing socioeconomic deprivation. (2023)
Journal Article

Background Multiple long-term conditions are rising across all groups but people experiencing socioeconomic deprivation are found to have a higher prevalence. Self-management strategies are a vital part of healthcare for people with long-term condit... Read More about Self-management of multiple long-term conditions: A systematic review of the barriers and facilitators amongst people experiencing socioeconomic deprivation..

Recommendations for improving the working conditions and cultures of distressed junior doctors, based on a qualitative study and stakeholder perspectives. (2022)
Journal Article

Background: Doctors, including junior doctors, are vulnerable to greater levels of distress and mental health difficulties than the public. This is exacerbated by their working conditions and cultures. While this vulnerability has been known for many... Read More about Recommendations for improving the working conditions and cultures of distressed junior doctors, based on a qualitative study and stakeholder perspectives..

Improving Medicines use in People with Polypharmacy in Primary Care (IMPPP): Protocol for a multicentre cluster randomised trial comparing a complex intervention for medication optimization against usual care. (2022)
Journal Article

IntroductionPolypharmacy is increasingly common, and associated with undesirable consequences. Polypharmacy management necessitates balancing therapeutic benefits and risks, and varying clinical and patient priorities. Current guidance for managing p... Read More about Improving Medicines use in People with Polypharmacy in Primary Care (IMPPP): Protocol for a multicentre cluster randomised trial comparing a complex intervention for medication optimization against usual care..

Can we mitigate the psychological impacts of social isolation using behavioural activation? Long-term results of the UK BASIL urgent public health COVID-19 pilot randomised controlled trial and living systematic review. (2022)
Journal Article

BACKGROUND: Behavioural and cognitive interventions remain credible approaches in addressing loneliness and depression. There was a need to rapidly generate and assimilate trial-based data during COVID-19. OBJECTIVES: We undertook a parallel pilot RC... Read More about Can we mitigate the psychological impacts of social isolation using behavioural activation? Long-term results of the UK BASIL urgent public health COVID-19 pilot randomised controlled trial and living systematic review..

Exploring the lived experience of Long Covid in black and minority ethnic groups in the UK: Protocol for qualitative interviews and art-based methods (2022)
Journal Article

Some people experience prolonged symptoms following an acute COVID-19 infection including fatigue, chest pain and breathlessness, headache and cognitive impairment. When symptoms persist for over 12 weeks following the initial infection, and are not... Read More about Exploring the lived experience of Long Covid in black and minority ethnic groups in the UK: Protocol for qualitative interviews and art-based methods.

The Impact of Colleague Suicide and the Current State of Postvention Guidance for Affected Co-Workers: A Critical Integrative Review. (2022)
Journal Article

People bereaved by suicide are affected psychologically and physically and may be at greater risk of taking their own lives. Whilst researchers have explored the impact of suicide on family members and friends, the area of colleague suicide has been... Read More about The Impact of Colleague Suicide and the Current State of Postvention Guidance for Affected Co-Workers: A Critical Integrative Review..

Associations of physician burnout with career engagement and quality of patient care: systematic review and meta-analysis (2022)
Journal Article

OBJECTIVE: To examine the association of physician burnout with the career engagement and the quality of patient care globally. DESIGN: Systematic review and meta-analysis. DATA SOURCES: Medline, PsycINFO, Embase, and CINAHL were searched from databa... Read More about Associations of physician burnout with career engagement and quality of patient care: systematic review and meta-analysis.

Under Pressure - Pharmacist's perceptions of the effects of postgraduate education on their wellbeing: a qualitative study (2022)
Presentation / Conference

Background: A 2019 NHS commission on the mental wellbeing of healthcare postgraduate learners reported research largely focused on doctors in training and identified the need for further research into the wellbeing needs and ways to support wellbein... Read More about Under Pressure - Pharmacist's perceptions of the effects of postgraduate education on their wellbeing: a qualitative study.

Cumulative complexity: a qualitative analysis of patients’ experiences of living with heart failure with preserved ejection fraction (2022)
Journal Article

Aims To investigate how heart failure with preserved ejection fraction (HFpEF), within the context of limited clinical services, impacts patients’ lives. Methods and results Secondary thematic analysis informed by the cumulative complexity model (CCM... Read More about Cumulative complexity: a qualitative analysis of patients’ experiences of living with heart failure with preserved ejection fraction.

Interventions to identify and manage depression delivered by ‘nontraditional’ providers to community-dwelling older adults: A realist review (2022)
Journal Article

BACKGROUND: Mental health problems experienced by older adults (60+ years of age) may remain hidden due to individual and system-level barriers. Opportunities to support early identification and management are therefore crucial. The National Health S... Read More about Interventions to identify and manage depression delivered by ‘nontraditional’ providers to community-dwelling older adults: A realist review.

Relationship between working conditions and psychological distress experienced by junior doctors in the UK during the COVID-19 pandemic: a cross-sectional survey study. (2022)
Journal Article

OBJECTIVES: This paper explored the self-reported prevalence of depression, anxiety and stress among junior doctors during the COVID-19 pandemic. It also reports the association between working conditions and psychological distress experienced by jun... Read More about Relationship between working conditions and psychological distress experienced by junior doctors in the UK during the COVID-19 pandemic: a cross-sectional survey study..

From detection to preparing for the end‐of‐life: A qualitative exploration of the South Asian family carers' experiences of the journey with dementia (2022)
Journal Article

People of South Asian (SA) origin have a higher prevalence of dementia compared with the United Kingdom (UK) population as a whole. Little is known about how family carers of SA origin perceive dementia, manage access to dementia services, and how pl... Read More about From detection to preparing for the end‐of‐life: A qualitative exploration of the South Asian family carers' experiences of the journey with dementia.

Investigating the links between diagnostic uncertainty, emotional exhaustion, and turnover intention in General Practitioners working in the United Kingdom (2022)
Journal Article

Background: General Practitioners (GPs) report high levels of burnout, job dissatisfaction, and turnover intention. The complexity of presenting problems to general practice makes diagnostic uncertainty a common occurrence that has been linked to bur... Read More about Investigating the links between diagnostic uncertainty, emotional exhaustion, and turnover intention in General Practitioners working in the United Kingdom.

Can we mitigate the psychological impacts of social isolation using behavioural activation? Long-term results of the UK BASIL Urgent Public Health COVID-19 pilot randomised controlled trial and living systematic review (2022)
Journal Article

Background Behavioural and cognitive interventions remain a credible approach in preventing loneliness and depression. There was a need to rapidly generate and assimilate trial-based data during COVID-19. Objectives We undertook a COVID-19 parallel p... Read More about Can we mitigate the psychological impacts of social isolation using behavioural activation? Long-term results of the UK BASIL Urgent Public Health COVID-19 pilot randomised controlled trial and living systematic review.

The experiences and needs of supporting individuals of young people who self-harm: A systematic review and thematic synthesis (2022)
Journal Article

Self-harm in young people is a serious international health concern that impacts on those providing informal support: the supporting individuals of young people. We aimed to highlight the experiences, views, and needs of these supporting individuals... Read More about The experiences and needs of supporting individuals of young people who self-harm: A systematic review and thematic synthesis.

Suicide and death by other causes among patients with a severe mental illness: cohort study comparing risks among patients discharged from inpatient care v. those treated in the community. (2022)
Journal Article

AIMS: People diagnosed with a severe mental illness (SMI) are at elevated risk of dying prematurely compared to the general population. We aimed to understand the additional risk among people with SMI after discharge from inpatient psychiatric care,... Read More about Suicide and death by other causes among patients with a severe mental illness: cohort study comparing risks among patients discharged from inpatient care v. those treated in the community..

A psychological intervention by community pharmacies to prevent depression in adults with subthreshold depression and long-term conditions: the CHEMIST pilot RCT (2022)
Journal Article

Background Depression is common in people with long-term health conditions, and this combination can lead to worsened health outcomes and increased health-care costs. Subthreshold depression, a risk factor for major depression, is prevalent in this p... Read More about A psychological intervention by community pharmacies to prevent depression in adults with subthreshold depression and long-term conditions: the CHEMIST pilot RCT.

Behavioural Activation for Social IsoLation (BASIL+) trial (Behavioural activation to mitigate depression and loneliness among older people with long-term conditions): Protocol for a fully-powered pragmatic randomised controlled trial. (2022)
Journal Article

Introduction Depression is a leading mental health problem worldwide. People with long-term conditions are at increased risk of experiencing depression. The COVID-19 pandemic led to strict social restrictions being imposed across the UK population... Read More about Behavioural Activation for Social IsoLation (BASIL+) trial (Behavioural activation to mitigate depression and loneliness among older people with long-term conditions): Protocol for a fully-powered pragmatic randomised controlled trial..

The feasibility and acceptability of a brief psychological intervention for adults with long-term health conditions and subthreshold depression delivered via community pharmacies: a mixed methods evaluation-the Community Pharmacies Mood Intervention Study (CHEMIST). (2022)
Journal Article

BACKGROUND: Adults with long-term health conditions (LTCs) are more likely to experience depressive symptoms which can worsen health outcomes and quality of life, and increase healthcare costs. Subthreshold depression may go undetected and/or untreat... Read More about The feasibility and acceptability of a brief psychological intervention for adults with long-term health conditions and subthreshold depression delivered via community pharmacies: a mixed methods evaluation-the Community Pharmacies Mood Intervention Study (CHEMIST)..

'You know where we are if you need us.' The role of primary care in supporting patients following pancreaticoduodenectomy for cancer: a qualitative study. (2022)
Journal Article

BACKGROUND: Ten percent of patients diagnosed with pancreatic cancer undergo pancreaticoduodenectomy. It is known that these patients have unmet psychological support needs, and GPs are key in enabling effective coordination of care for people living... Read More about 'You know where we are if you need us.' The role of primary care in supporting patients following pancreaticoduodenectomy for cancer: a qualitative study..

The perceptions of general practice among Central and Eastern Europeans in the United Kingdom: A systematic scoping review (2022)
Journal Article

BACKGROUND: Around 2 million people have migrated from Central and Eastern Europe to the UK since 2004. The UK Central and Eastern European Community (UK-CEE) are disproportionately exposed to the social determinants of poor physical and mental healt... Read More about The perceptions of general practice among Central and Eastern Europeans in the United Kingdom: A systematic scoping review.

Multicentre randomised controlled trial of a group psychological intervention for postnatal depression in British mothers of South Asian origin (ROSHNI-2): study protocol (2022)
Journal Article

Background In the UK, postnatal depression is more common in British South Asian women than White Caucasion women. Cognitive–behavioural therapy (CBT) is recommended as a first-line treatment, but there is little evidence for the adaptation of CBT f... Read More about Multicentre randomised controlled trial of a group psychological intervention for postnatal depression in British mothers of South Asian origin (ROSHNI-2): study protocol.

Emotional distress, anxiety and depression in South Asians with long-term conditions: a qualitative systematic review (2021)
Journal Article

Background: People with physical-mental comorbidity have a poorer quality of life, worse clinical outcomes and increased mortality compared to people with physical conditions alone. South Asians (SAs) are the largest minority group in the UK and a... Read More about Emotional distress, anxiety and depression in South Asians with long-term conditions: a qualitative systematic review.

'It's always in the back of my mind': understanding the psychological impact of recovery following pancreaticoduodenectomy for cancer: a qualitative study. (2021)
Journal Article

OBJECTIVES: Ten per cent of patients diagnosed with pancreatic cancer undergo pancreaticoduodenectomy. There is limited previous research focusing on psychological well-being; unmet support needs impact negatively on quality of life. This paper repor... Read More about 'It's always in the back of my mind': understanding the psychological impact of recovery following pancreaticoduodenectomy for cancer: a qualitative study..

Suicide and other causes of death among working-age and older adults in the year after discharge from in-patient mental healthcare in England: matched cohort study (2021)
Journal Article

Background Evidence for risk of dying by suicide and other causes following discharge from in-patient psychiatric care throughout adulthood is sparse. Aims To estimate risks of all-cause mortality, natural and external-cause deaths, suicide and ac... Read More about Suicide and other causes of death among working-age and older adults in the year after discharge from in-patient mental healthcare in England: matched cohort study.

What challenges did junior doctors face while working during the COVID-19 pandemic? A qualitative study. (2021)
Journal Article

OBJECTIVES: This paper reports findings exploring junior doctors' experiences of working during the COVID-19 pandemic in the UK. DESIGN: Qualitative study using in-depth interviews with 15 junior doctors. Interviews were audio-recorded, transcribed,... Read More about What challenges did junior doctors face while working during the COVID-19 pandemic? A qualitative study..

Risk factors for nonfatal self‐harm and suicide among adolescents: two nested case–control studies conducted in the UK Clinical Practice Research Datalink (2021)
Journal Article

BackgroundThe characteristics of adolescents who die by suicide have hitherto been examined in uncontrolled study designs, thereby precluding examination of risk factors. The degree to which antecedents of nonfatal self‐harm and suicide at young age... Read More about Risk factors for nonfatal self‐harm and suicide among adolescents: two nested case–control studies conducted in the UK Clinical Practice Research Datalink.

Community Ageing Research 75+ (CARE75+) REMOTE study: a remote model of recruitment and assessment of the health, well-being and social circumstances of older people (2021)
Journal Article

IntroductionThe Community Ageing Research 75+ (CARE75+) study is a longitudinal cohort study collecting extensive health and social data, with a focus on frailty, independence and quality of life in older age. CARE75+ was the first international expe... Read More about Community Ageing Research 75+ (CARE75+) REMOTE study: a remote model of recruitment and assessment of the health, well-being and social circumstances of older people.

Interventions for preventing relapse or recurrence of major depressive disorder in adults in a primary care setting: a network meta-analysis (2021)
Journal Article

Objectives This is a protocol for a Cochrane Review (intervention). The objectives are as follows: The aim is to assess, using network meta‐analysis (NMA), the effectiveness and safety of interventions for preventing relapse‐recurrence of depress... Read More about Interventions for preventing relapse or recurrence of major depressive disorder in adults in a primary care setting: a network meta-analysis.

Association of SARS-CoV-2 Infection With Psychological Distress, Psychotropic Prescribing, Fatigue, and Sleep Problems Among UK Primary Care Patients. (2021)
Journal Article

Importance: Infection with SARS-CoV-2 is associated with fatigue and sleep problems long after the acute phase of COVID-19. In addition, there are concerns of SARS-CoV-2 infection causing psychiatric illness; however, evidence of a direct effect is i... Read More about Association of SARS-CoV-2 Infection With Psychological Distress, Psychotropic Prescribing, Fatigue, and Sleep Problems Among UK Primary Care Patients..

Behavioural activation to prevent depression and loneliness among socially isolated older people with long-term conditions: The BASIL COVID-19 pilot randomised controlled trial. (2021)
Journal Article

BACKGROUND: Older adults, including those with long-term conditions (LTCs), are vulnerable to social isolation. They are likely to have become more socially isolated during the Coronavirus Disease 2019 (COVID-19) pandemic, often due to advice to "shi... Read More about Behavioural activation to prevent depression and loneliness among socially isolated older people with long-term conditions: The BASIL COVID-19 pilot randomised controlled trial..

Integrating case-finding and initial management for osteoarthritis, anxiety, and depression into primary care long-term condition reviews: results from the ENHANCE pilot trial. (2021)
Journal Article

Background: Multimorbidity is increasingly the norm; however, primary care remains focused on single diseases. Osteoarthritis, anxiety, and depression are frequently comorbid with other long-term conditions (LTCs), but rarely prioritized by clinician... Read More about Integrating case-finding and initial management for osteoarthritis, anxiety, and depression into primary care long-term condition reviews: results from the ENHANCE pilot trial..

Clinicians' and patients' experiences of managing heart failure during the COVID-19 pandemic: a qualitative study (2021)
Journal Article

BACKGROUND: The SARS-CoV-2 Coronavirus Disease (COVID-19) resulted in unprecedented societal and healthcare provision change that has been implemented at pace. Little is known about the indirect impacts of these changes and what the future effects ma... Read More about Clinicians' and patients' experiences of managing heart failure during the COVID-19 pandemic: a qualitative study.

Still 'being bothered about Billy': managing the physical health of people with severe mental illness. (2021)
Journal Article

People with severe mental illness (SMI) face a future not only limited by stigmatising psychiatric illness, but also a life shortened by 15–20 years through physical comorbidities. Social and behavioural determinants help explain why many of these co... Read More about Still 'being bothered about Billy': managing the physical health of people with severe mental illness..

The development and validation of a prognostic model to PREDICT Relapse of depression in adult patients in primary care: protocol for the PREDICTR study. (2021)
Journal Article

BACKGROUND: Most patients who present with depression are treated in primary care by general practitioners (GPs). Relapse of depression is common (at least 50% of patients treated for depression will relapse after a single episode) and leads to consi... Read More about The development and validation of a prognostic model to PREDICT Relapse of depression in adult patients in primary care: protocol for the PREDICTR study..

Protective factors and sources of support in the workplace as experienced by UK foundation and junior doctors: a qualitative study (2021)
Journal Article

OBJECTIVES: This paper reports findings identifying foundation and junior doctors' experiences of occupational and psychological protective factors in the workplace and sources of effective support. DESIGN: Interpretative, inductive, qualitative stud... Read More about Protective factors and sources of support in the workplace as experienced by UK foundation and junior doctors: a qualitative study.

Sources of work-related psychological distress experienced by UK-wide foundation and junior doctors: a qualitative study. (2021)
Journal Article

OBJECTIVES: This paper reports findings exploring work cultures, contexts and conditions associated with psychological distress in foundation and junior doctors. DESIGN: Qualitative study using in-depth interviews with 21 junior doctor participants.... Read More about Sources of work-related psychological distress experienced by UK-wide foundation and junior doctors: a qualitative study..

Can We Prevent Depression in At-Risk Older Adults Using Self-Help? The UK SHARD Trial of Behavioral Activation. (2021)
Journal Article

BACKGROUND: Treatment of established depression is the dominant approach to care of older adults, but prevention holds much promise. Self-help interventions are a feasible preventive approach, since they are scalable and low cost. There are few trial... Read More about Can We Prevent Depression in At-Risk Older Adults Using Self-Help? The UK SHARD Trial of Behavioral Activation..

Mitigating the psychological impacts of COVID-19 restrictions: The Behavioural Activation in Social Isolation (BASIL) pilot randomised controlled trial to prevent depression and loneliness among older people with long term conditions (2021)
Journal Article

Background: Older adults with long-term conditions have become more socially isolated (often due to advice to shield to protect them from COVID-19) and are thus at particular risk of depression and loneliness. There is a need for brief scalable psyc... Read More about Mitigating the psychological impacts of COVID-19 restrictions: The Behavioural Activation in Social Isolation (BASIL) pilot randomised controlled trial to prevent depression and loneliness among older people with long term conditions.

Experiences of general practice care for self-harm: a qualitative study of young people's perspectives. (2021)
Journal Article

BACKGROUND: Self-harm is a growing concern and rates of self-harm in young people presenting to general practice are rising. There is however an absence of evidence on young people's experiences of GP care and on accessing general practice. AIM: To e... Read More about Experiences of general practice care for self-harm: a qualitative study of young people's perspectives..

Temporal trends in annual incidence rates for psychiatric disorders and self-harm among children and adolescents in the UK, 2003-2018. (2021)
Journal Article

BACKGROUND: There has been growing concern in the UK over recent years that a perceived mental health crisis is affecting children and adolescents, although published epidemiological evidence is limited. METHODS: Two population-based UK primary care... Read More about Temporal trends in annual incidence rates for psychiatric disorders and self-harm among children and adolescents in the UK, 2003-2018..

Assessing the severity of cardiovascular disease in 213 088 patients with coronary heart disease: a retrospective cohort study. (2021)
Journal Article

OBJECTIVE: Most current cardiovascular disease (CVD) risk stratification tools are for people without CVD, but very few are for prevalent CVD. In this study, we developed and validated a CVD severity score in people with coronary heart disease (CHD)... Read More about Assessing the severity of cardiovascular disease in 213 088 patients with coronary heart disease: a retrospective cohort study..

Comparative differences in musculoskeletal pain consultation and analgesic prescription for people with dementia: a UK-wide matched cohort study (2021)
Journal Article

Painful musculoskeletal conditions are common in older adults; however, pain identification, assessment, and management are reported to be suboptimal for people with dementia. Adequate pain management is an integral aspect of care for people with dem... Read More about Comparative differences in musculoskeletal pain consultation and analgesic prescription for people with dementia: a UK-wide matched cohort study.

Switching antipsychotics to support the physical health of people with severe mental illness: A qualitative study of healthcare professionals' perspectives (2021)
Journal Article

OBJECTIVES: The side effects of antipsychotic medications (APs) can increase the risk of developing physical health conditions. Some APs pose a higher risk than others. Evidence suggests switching to lower risk APs can support physical health outcome... Read More about Switching antipsychotics to support the physical health of people with severe mental illness: A qualitative study of healthcare professionals' perspectives.

Effects of the COVID-19 pandemic on primary care-recorded mental illness and self-harm episodes in the UK: a population-based cohort study (2021)
Journal Article

BACKGROUND: The COVID-19 pandemic has adversely affected population mental health. We aimed to assess temporal trends in primary care-recorded common mental illness, episodes of self-harm, psychotropic medication prescribing, and general practitioner... Read More about Effects of the COVID-19 pandemic on primary care-recorded mental illness and self-harm episodes in the UK: a population-based cohort study.

A pilot study of a nurse-led integrated care review (the INCLUDE review) for people with inflammatory rheumatological conditions in primary care: feasibility study findings. (2021)
Journal Article

BACKGROUND: People with inflammatory rheumatological conditions such as rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, polymyalgia rheumatica and giant cell arteritis are at an increased risk of common comorbidities including card... Read More about A pilot study of a nurse-led integrated care review (the INCLUDE review) for people with inflammatory rheumatological conditions in primary care: feasibility study findings..

Challenges in the management of people with heart failure with preserved ejection fraction (HFpEF) in primary care: a qualitative study of general practitioner perspectives (2021)
Journal Article

Objectives: To explore the perspectives of general practitioners (GPs) on the identification and management of people, including those from ethnic minority groups, with Heart Failure with Preserved Ejection Fraction (HFpEF). Methods: Qualitative stud... Read More about Challenges in the management of people with heart failure with preserved ejection fraction (HFpEF) in primary care: a qualitative study of general practitioner perspectives.

Exploring women's experiences of identifying, negotiating and managing perinatal anxiety: a qualitative study (2020)
Journal Article

OBJECTIVES: Anxiety affects around 15% of women during the perinatal period and can adversely impact both mother and child, with potential implications for long-term health; few studies have examined women's experiences of perinatal anxiety (PNA). In... Read More about Exploring women's experiences of identifying, negotiating and managing perinatal anxiety: a qualitative study.

Understanding the management of heart failure with preserved ejection fraction: a qualitative multiperspective study. (2020)
Journal Article

BACKGROUND: About half of all people with heart failure have heart failure with preserved ejection fraction (HFpEF), in which the heart is stiff. This type of heart failure is more common in older people with a history of hypertension, obesity, and d... Read More about Understanding the management of heart failure with preserved ejection fraction: a qualitative multiperspective study..

Does anxiety moderate the effectiveness of mirtazapine in patients with treatment-resistant depression? A secondary analysis of the MIR trial. (2020)
Journal Article

BACKGROUND: There is a lack of evidence to guide treatment of comorbid depression and anxiety. Preliminary evidence suggests mirtazapine may be effective in treating patients with both depression and anxiety symptoms. METHODS: We undertook a secondar... Read More about Does anxiety moderate the effectiveness of mirtazapine in patients with treatment-resistant depression? A secondary analysis of the MIR trial..

Access to psychological support for young people following stoma surgery: Exploring patients’ and clinicians’ perspectives (2020)
Journal Article

Psychological problems are common among people with inflammatory bowel disease (IBD) following stoma surgery. However, the ways in which stoma-related psychological needs are identified and addressed in healthcare settings remain unexplored. In this... Read More about Access to psychological support for young people following stoma surgery: Exploring patients’ and clinicians’ perspectives.

Acute myocardial infarction in several mental illness: a nationwide analysis of prevalence, management strategies and outcomes (2020)
Journal Article

Background Severe mental illness (SMI) is associated with an increased risk of cardiovascular disease and mortality. However, it is unclear whether SMI patients are just as likely to receive guideline-recommended therapy for AMI as those without men... Read More about Acute myocardial infarction in several mental illness: a nationwide analysis of prevalence, management strategies and outcomes.

The experiences of general practitioner partners living with distress: An interpretative phenomenological analysis (2020)
Journal Article

Doctors, including general practitioners, experience higher levels of mental illness than the general population. General practitioners who are partners in their practices may face heightened stress. In total, 10 general practitioner partners living... Read More about The experiences of general practitioner partners living with distress: An interpretative phenomenological analysis.

A relational analysis of an invisible illness: A meta-ethnography of people with chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) and their support needs (2020)
Journal Article

Chronic fatigue syndrome (CFS)/myalgic encephalomyelitis (ME) is indicated by prolonged, medically unexplained fatigue (amongst other symptoms), not alleviated by rest, and causing substantial disability. There are limited treatments on offer, which... Read More about A relational analysis of an invisible illness: A meta-ethnography of people with chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) and their support needs.

Temporal Trends in Pregnancy‐Associated Stroke and Its Outcomes Among Women With Hypertensive Disorders of Pregnancy (2020)
Journal Article

Background Stroke is a serious complication of hypertensive disorders of pregnancy (HDP), with potentially severe and long-term sequelae. However, the temporal trends, predictors and outcomes of stroke in women with HDP at delivery remain unknown.... Read More about Temporal Trends in Pregnancy‐Associated Stroke and Its Outcomes Among Women With Hypertensive Disorders of Pregnancy.

Does anxiety moderate the efficacy of mirtazapine in patients with treatment resistant depression? A secondary analysis of the mir trial (2020)
Presentation / Conference

Introduction: Mirtazapine has been shown to be effective in treating patients with both depression and anxiety symptoms.1 This has not been examined in primary care. Objectives: We examined whether anxiety moderated the effect of mirtazapine com... Read More about Does anxiety moderate the efficacy of mirtazapine in patients with treatment resistant depression? A secondary analysis of the mir trial.

Routine laboratory surveillance of antimicrobial resistance in community-acquired urinary tract infections adequately informs prescribing policy in England (2020)
Journal Article

Objectives To assess whether resistance estimates obtained from sentinel surveillance for antimicrobial resistance (AMR) in community-acquired urinary tract infections (UTIs) differ from routinely collected laboratory community UTI data. Methods... Read More about Routine laboratory surveillance of antimicrobial resistance in community-acquired urinary tract infections adequately informs prescribing policy in England.

The challenge of pain identification, assessment, and management in people with dementia: a qualitative study (2020)
Journal Article

Background Painful conditions are common in older adults, including people with dementia. The symptoms associated with dementia (for example, diminished language capacity, memory impairment, and behavioural changes), however, may lead to the suboptim... Read More about The challenge of pain identification, assessment, and management in people with dementia: a qualitative study.

Development and validation of the DIabetes Severity SCOre (DISSCO) in 139 626 individuals with type 2 diabetes: a retrospective cohort study. (2020)
Journal Article

OBJECTIVE: Clinically applicable diabetes severity measures are lacking, with no previous studies comparing their predictive value with glycated hemoglobin (HbA1c). We developed and validated a type 2 diabetes severity score (the DIabetes Severity SC... Read More about Development and validation of the DIabetes Severity SCOre (DISSCO) in 139 626 individuals with type 2 diabetes: a retrospective cohort study..

'We're the First Port of Call' - Perspectives of Ambulance Staff on Responding to Deaths by Suicide: A Qualitative Study (2020)
Journal Article

Introduction: Exposure to suicide is a known risk factor for suicide. Ambulance staff are exposed to work-related stressors including attending suicides, which may elevate their risk for mental health problems/suicide. Little is known about ambulance... Read More about 'We're the First Port of Call' - Perspectives of Ambulance Staff on Responding to Deaths by Suicide: A Qualitative Study.

Undertaking an integrated nurse led review (INCLUDE) for patients with inflammatory conditions: does it change management of morbidities? (2020)
Journal Article

Background People with inflammatory rheumatological conditions (IRCs), including rheumatoid arthritis (RA), ankylosing spondylitis (AS), psoriatic arthritis (PsA), polymyalgia rheumatica (PMR) and giant cell arteritis (GCA), are at an increased risk... Read More about Undertaking an integrated nurse led review (INCLUDE) for patients with inflammatory conditions: does it change management of morbidities?.

EXPERIENCES OF DELIVERING A NURSE-LED FRACTURE RISK ASSESSMENT FOR PATIENTS WITH INFLAMMATORY RHEUMATOLOGICAL CONDITIONS IN PRIMARY CARE (2020)
Presentation / Conference

Background The INCLUDE (INtegrating and improving Care for patients with infLammatory rheUmatological DisordErs in the community) pilot trial aimed to evaluate the feasibility and acceptability of a nurse-delivered review in primary care for people... Read More about EXPERIENCES OF DELIVERING A NURSE-LED FRACTURE RISK ASSESSMENT FOR PATIENTS WITH INFLAMMATORY RHEUMATOLOGICAL CONDITIONS IN PRIMARY CARE.

P193 Experiences of delivering a nurse-led fracture risk assessment for patients with inflammatory rheumatological conditions in primary care (2020)
Journal Article

Background The INCLUDE (INtegrating and improving Care for patients with infLammatory rheUmatological DisordErs in the community) pilot trial aimed to evaluate the feasibility and acceptability of a nurse-delivered review in primary care for people... Read More about P193 Experiences of delivering a nurse-led fracture risk assessment for patients with inflammatory rheumatological conditions in primary care.

Temporal Changes in Hypertensive Disorders of Pregnancy and Impact on Cardiovascular and Obstetric Outcomes (2020)
Journal Article

Hypertensive disorders of pregnancy (HDP) are a major cause of maternal morbidity. However, short-term outcomes of HDP subgroups remain unknown. Using National Inpatient Sample database, all delivery hospitalizations between 2004 and 2014 with or wit... Read More about Temporal Changes in Hypertensive Disorders of Pregnancy and Impact on Cardiovascular and Obstetric Outcomes.

Prognostic value of first-recorded breathlessness for future chronic respiratory and heart disease: a cohort study using a UK national primary care database (2020)
Journal Article

Background: Breathlessness is a common presentation in primary care, but GPs may not always record a diagnosis. Aim: To assess long-term risk of diagnosed COPD, asthma and IHD, and mortality in patients with undiagnosed breathlessness. Design and... Read More about Prognostic value of first-recorded breathlessness for future chronic respiratory and heart disease: a cohort study using a UK national primary care database.

Stratified primary care versus non-stratified care for musculoskeletal pain: qualitative findings from the STarT MSK feasibility and pilot cluster randomized controlled trial (2020)
Journal Article

BACKGROUND: Stratified care involves subgrouping patients based on key characteristics, e.g. prognostic risk, and matching these subgroups to appropriate early treatment options. The STarT MSK feasibility and pilot cluster randomised controlled trial... Read More about Stratified primary care versus non-stratified care for musculoskeletal pain: qualitative findings from the STarT MSK feasibility and pilot cluster randomized controlled trial.

Optimising Management of Patients with Heart Failure with Preserved Ejection Fraction in Primary Care (OPTIMISE-HFpEF): Rationale and Protocol for a Multi-Method Study (2020)
Journal Article

Background: Heart failure with preserved ejection fraction (HFpEF) is less well understood than heart failure with reduced ejection fraction (HFrEF), with greater diagnostic difficulty and management uncertainty. Aim: Our primary aim is to develop an... Read More about Optimising Management of Patients with Heart Failure with Preserved Ejection Fraction in Primary Care (OPTIMISE-HFpEF): Rationale and Protocol for a Multi-Method Study.

Evaluation of the Impact of the PABBS Suicide Bereavement Training on Clinicians' Knowledge and Skills. (2020)
Journal Article

Background: Health-care professionals do not routinely receive training on how best to support parents bereaved by suicide. Evidence-based training - Postvention Assisting Those Bereaved by Suicide (PABBS) - was designed to address this gap. Aims: Th... Read More about Evaluation of the Impact of the PABBS Suicide Bereavement Training on Clinicians' Knowledge and Skills..

The association between anxiety and disease activity and quality of life in rheumatoid arthritis: a systematic review and meta-analysis. (2020)
Journal Article

OBJECTIVES: In people with rheumatoid arthritis (RA), mental health problems are common, but often not recognized or treated, contributing to increased morbidity and mortality. Most studies examining the impact of mental health problems in RA have fo... Read More about The association between anxiety and disease activity and quality of life in rheumatoid arthritis: a systematic review and meta-analysis..

Patterns of symptoms before a diagnosis of first episode psychosis: a latent class analysis of UK primary care electronic health records. (2019)
Journal Article

Background: The nature of symptoms in the prodromal period of first episode psychosis (FEP) remains unclear. The objective was to determine patterns of symptoms recorded in primary care in the 5-years before FEP diagnosis. Methods: The study was s... Read More about Patterns of symptoms before a diagnosis of first episode psychosis: a latent class analysis of UK primary care electronic health records..

PPatients' and general practitioners' views and experiences of stratified primary care for patients with musculoskeletal pain: qualitative findings from the STarT MSK feasibility and pilot trial. (2019)
Conference Proceeding

Background Improving primary care management of musculoskeletal (MSK) pain is a priority. A pilot cluster RCT tested prognostic stratified care for patients with common MSK pain presentations, including low back pain, in 8 UK general practices (4 st... Read More about PPatients' and general practitioners' views and experiences of stratified primary care for patients with musculoskeletal pain: qualitative findings from the STarT MSK feasibility and pilot trial..

Embracing a ‘new normal’: the construction of biographical renewal in young adults’ narratives of living with a stoma (2019)
Journal Article

Stoma surgery can be a life-changing procedure due to bodily changes and related psychological responses. Despite previous literature identifying unique challenges for young adults living with a long-term condition, no studies have explored the biogr... Read More about Embracing a ‘new normal’: the construction of biographical renewal in young adults’ narratives of living with a stoma.

Healthcare professionals' perspectives on identifying and managing perinatal anxiety: a qualitative study. (2019)
Journal Article

BACKGROUND: Perinatal mental health problems are those that occur during pregnancy or up to 12 months postpartum, and affect up to 20% of women. Perinatal anxiety (PNA) is at least as common as depression during the perinatal phase and can adversely... Read More about Healthcare professionals' perspectives on identifying and managing perinatal anxiety: a qualitative study..

Non-traditional support workers delivering a brief psychosocial intervention for older people with anxiety and depression: the NOTEPAD feasibility study (2019)
Report

BACKGROUND:Anxiety and depression often coexist in older people. These disorders are often underdiagnosed and undertreated, and are associated with increased use of health and social care services, and raised mortality. Barriers to diagnosis include... Read More about Non-traditional support workers delivering a brief psychosocial intervention for older people with anxiety and depression: the NOTEPAD feasibility study.

The comorbidity burden of type 2 diabetes mellitus: patterns, clusters and predictions from a large English primary care cohort. (2019)
Journal Article

BACKGROUND: The presence of additional chronic conditions has a significant impact on the treatment and management of type 2 diabetes (T2DM). Little is known about the patterns of comorbidities in this population. The aims of this study are to quanti... Read More about The comorbidity burden of type 2 diabetes mellitus: patterns, clusters and predictions from a large English primary care cohort..

Acute Myocardial Infarction in Severe Mental Illness: prevalence, clinical outcomes and process of care in United States hospitalizations. (2019)
Journal Article

Patients with severe mental illness (SMI) are a high-risk group for cardiovascular disease. The present study examined the prevalence and outcomes of SMI patients in a national AMI cohort. SMI has doubled in prevalence amongst AMI patients, mainly du... Read More about Acute Myocardial Infarction in Severe Mental Illness: prevalence, clinical outcomes and process of care in United States hospitalizations..

Depression predicts emergency care use in people with chronic obstructive pulmonary disease: a large cohort study in primary care. (2019)
Journal Article

Background: Depression is common in people with chronic obstructive pulmonary disease (COPD) and has been associated with a variety of poor outcomes. A large proportion of health care costs in the UK are spent on emergency care. This study examined t... Read More about Depression predicts emergency care use in people with chronic obstructive pulmonary disease: a large cohort study in primary care..

Community Pharmacies Mood Intervention Study (CHEMIST): feasibility and external pilot randomised controlled trial protocol. (2019)
Journal Article

Feasibility study: Objectives:Refine a bespoke enhanced support intervention (ESI) (including self-help materials, intervention manual and training) for implementation by community pharmacy (CP) staff to people with sub-threshold depression and long-... Read More about Community Pharmacies Mood Intervention Study (CHEMIST): feasibility and external pilot randomised controlled trial protocol..

Patient and Public Involvement and Engagement in a doctoral research project exploring self-harm in older adults (2019)
Journal Article

Background The contribution of involving patients and public in health research is widely reported, particularly within mental health research. Less is written about such contributions to doctoral research. The research focus of this doctoral resear... Read More about Patient and Public Involvement and Engagement in a doctoral research project exploring self-harm in older adults.

040 The incidence of anxiety or depression in patients with and without inflammatory rheumatic conditions (2019)
Journal Article

Background: Rheumatoid arthritis (RA) has been linked to several co-morbidities, including anxiety and depression, which can contribute to increased morbidity and mortality. Less literature has examined the association between other inflammatory rheu... Read More about 040 The incidence of anxiety or depression in patients with and without inflammatory rheumatic conditions.

088 The impact of anxiety on quality of life and disease activity in rheumatoid arthritis: a systematic review (2019)
Journal Article

Background: Co-morbid anxiety and depression are frequent in patients with rheumatoid arthritis (RA), but are often under-recognised and under-treated, contributing to increased morbidity and mortality. Most studies examining the impact of mood probl... Read More about 088 The impact of anxiety on quality of life and disease activity in rheumatoid arthritis: a systematic review.

E059 Development of a nurse-led integrated care review based in primary care to identify and improve the management of co-morbidities in patients with inflammatory rheumatological conditions: the INCLUDE study (2019)
Journal Article

Background: People with inflammatory rheumatological conditions (IRCs) are at an increased risk of common comorbidities such as cardiovascular disease (CVD), osteoporosis, anxiety and depression. These are often not recognised or treated and can lead... Read More about E059 Development of a nurse-led integrated care review based in primary care to identify and improve the management of co-morbidities in patients with inflammatory rheumatological conditions: the INCLUDE study.

A systematic review of measures using clinical data for assessing the severity of Type 2 diabetes (2019)
Presentation / Conference

Background/Aims: The assessment of disease severity in people with diabetes enables identification of patients in need for intensive and targeted therapies, and could help optimise the allocation of healthcare resources. We aimed to identify and appr... Read More about A systematic review of measures using clinical data for assessing the severity of Type 2 diabetes.

Pain assessment and pain treatment for community-dwelling people with dementia: A systematic review and narrative synthesis (2019)
Journal Article

OBJECTIVES: To describe the current literature on pain assessment and pain treatment for community-dwelling people with dementia. METHOD: A comprehensive systematic search of the literature with narrative synthesis was conducted. Eight major... Read More about Pain assessment and pain treatment for community-dwelling people with dementia: A systematic review and narrative synthesis.

Can support workers from AgeUK deliver an intervention to support older people with anxiety and depression? A qualitative evaluation. (2019)
Journal Article

BACKGROUND: Anxiety and depression often co-exist. These disorders are under-diagnosed and under-treated, specifically among older people, and lead to increased use of health and social care services and raised mortality. Older people report a reluct... Read More about Can support workers from AgeUK deliver an intervention to support older people with anxiety and depression? A qualitative evaluation..

The value of an embedded qualitative study in a trial of a second antidepressant for people who had not responded to one antidepressant: understanding the perspectives of patients and general practitioners (2018)
Journal Article

BACKGROUND: Depression is the leading cause of disability worldwide, and is a major contributor to the overall global burden of disease. The number of prescriptions for antidepressants has risen dramatically in recent years yet up to 50% of patients... Read More about The value of an embedded qualitative study in a trial of a second antidepressant for people who had not responded to one antidepressant: understanding the perspectives of patients and general practitioners.

Self-harm in a primary care cohort of older people: incidence, clinical management, and risk of suicide and other causes of death (2018)
Journal Article

BACKGROUND: Self-harm is a major risk factor for suicide, with older adults (older than 65 years) having reportedly greater suicidal intent than any other age group. With the aging population rising and paucity of research focus in this age group, th... Read More about Self-harm in a primary care cohort of older people: incidence, clinical management, and risk of suicide and other causes of death.

Mirtazapine added to SSRIs or SNRIs for treatment resistant depression in primary care: phase III randomised placebo controlled trial (MIR) (2018)
Journal Article

OBJECTIVE: To investigate the effectiveness of combining mirtazapine with serotonin-noradrenaline reuptake inhibitor (SNRI) or selective serotonin reuptake inhibitor (SSRI) antidepressants for treatment resistant depression in primary care. DESIGN: T... Read More about Mirtazapine added to SSRIs or SNRIs for treatment resistant depression in primary care: phase III randomised placebo controlled trial (MIR).

MIRtazapine added to SSRIs or SNRIs for Treatment Resistant Depression in Primary Care: a placebo controlled randomised trial (MIR) (2018)
Journal Article

Objective: To investigate the effectiveness of combining mirtazapine with Serotonin-Noradrenaline Reuptake Inhibitor (SNRI) or Selective Serotonin Reuptake Inhibitor (SSRI) antidepressants for patients in primary care who had not responded to an anti... Read More about MIRtazapine added to SSRIs or SNRIs for Treatment Resistant Depression in Primary Care: a placebo controlled randomised trial (MIR).

Association Between Physician Burnout and Patient Safety, Professionalism, and Patient Satisfaction: A Systematic Review and Meta-analysis. (2018)
Journal Article

Importance: Physician burnout has taken the form of an epidemic that may affect core domains of health care delivery, including patient safety, quality of care, and patient satisfaction. However, this evidence has not been systematically quantified.... Read More about Association Between Physician Burnout and Patient Safety, Professionalism, and Patient Satisfaction: A Systematic Review and Meta-analysis..

Attending away from the body predicts increased physical symptom reports at six months in primary care patients (2018)
Journal Article

Objective High symptom reporting (HSR) and medically unexplained symptoms (MUS) are associated with considerable distress, disability, healthcare utilization and costs, but are poorly understood, and current treatments are of limited benefit. Most mo... Read More about Attending away from the body predicts increased physical symptom reports at six months in primary care patients.

Self-reported sleep duration and quality and cardiovascular disease and mortality: a dose-response meta-analysis (2018)
Journal Article

Abstract Background: There is growing evidence that sleep duration and quality may be associated with cardiovascular harm and mortality. Methods and Results: We conducted a systematic review, meta-analysis and spline analysis of prospective cohort st... Read More about Self-reported sleep duration and quality and cardiovascular disease and mortality: a dose-response meta-analysis.

Long-term clinical and cost-effectiveness of collaborative care (versus usual care) for people with mental–physical multimorbidity: cluster-randomised trial (2018)
Journal Article

Background Collaborative care can support the treatment of depression in people with long-term conditions, but long-term benefits and costs are unknown. Aims To explore the long-term (24-month) effectiveness and cost-effectiveness of collaborati... Read More about Long-term clinical and cost-effectiveness of collaborative care (versus usual care) for people with mental–physical multimorbidity: cluster-randomised trial.

How should we implement collaborative care for older people with depression? A qualitative study using normalisation process theory within the CASPER plus trial (2018)
Journal Article

BACKGROUND: Depression in older people may have a prevalence as high as 20%, and is associated with physical co-morbidities, loss, and loneliness. It is associated with poorer health outcomes and reduced quality of life, and is under-diagnosed and un... Read More about How should we implement collaborative care for older people with depression? A qualitative study using normalisation process theory within the CASPER plus trial.

Using electronic health records to quantify and stratify the severity of type 2 diabetes in primary care in England: rationale and cohort study design (2018)
Journal Article

Introduction: The increasing prevalence of type 2 diabetes (T2DM) presents a significant burden on affected individuals and health-care systems internationally. There is, however, no agreed validated measure to infer diabetes severity from electronic... Read More about Using electronic health records to quantify and stratify the severity of type 2 diabetes in primary care in England: rationale and cohort study design.

Long-term clinical and cost-effectiveness of collaborative care (vs. usual care): a cluster-randomised trial (2018)
Journal Article

Background Collaborative care can support the treatment of depression in people with long-term conditions, but long-term benefits and costs are unknown. Aims To explore the long-term (24-month) effectiveness and cost-effectiveness of collaborati... Read More about Long-term clinical and cost-effectiveness of collaborative care (vs. usual care): a cluster-randomised trial.

‘Treading water but drowning slowly’: what are GPs’ experiences of living and working with mental illness and distress in England? A qualitative study (2018)
Journal Article

Objectives This paper provides an in-depth account of general practitioners’ (GPs) experiences of living and working with mental illness and distress, as part of a wider study reporting the barriers and facilitators to help-seeking for mental illnes... Read More about ‘Treading water but drowning slowly’: what are GPs’ experiences of living and working with mental illness and distress in England? A qualitative study.

Cost-Utility Analysis of Routine Anxiety and Depression Screening in Patients Consulting for Osteoarthritis: Results From a Clinical, Randomized Controlled Trial (2018)
Journal Article

OBJECTIVE: To investigate the cost-effectiveness (cost-utility) of introducing general practitioner screening for anxiety and depression in patients consulting with osteoarthritis (OA). METHODS: A cluster-randomised trial-based economic evaluation to... Read More about Cost-Utility Analysis of Routine Anxiety and Depression Screening in Patients Consulting for Osteoarthritis: Results From a Clinical, Randomized Controlled Trial.

i049 The importance of identifying and managing co-morbid anxiety and depression in people with rheumatological conditions (2018)
Journal Article

Anxiety and depression are common mental disorders and major contributors to the overall global burden of disease. Depression is a risk factor for suicide. Where anxiety and depression are co-morbid with a long term physical condition, the morbidity... Read More about i049 The importance of identifying and managing co-morbid anxiety and depression in people with rheumatological conditions.

A randomised controlled trial, cost-effectiveness and process evaluation of the implementation of self-management for chronic gastrointestinal disorders in primary care, and linked projects on identification and risk assessment (2018)
Journal Article

Background Chronic gastrointestinal disorders are major burdens in primary care. Although there is some evidence that enhancing self-management can improve outcomes, it is not known if such models of care can be implemented at scale in routine NHS s... Read More about A randomised controlled trial, cost-effectiveness and process evaluation of the implementation of self-management for chronic gastrointestinal disorders in primary care, and linked projects on identification and risk assessment.

Findings from a feasibility study to improve GP elicitation of patient concerns in UK General Practice consultations (2018)
Journal Article

Objectives To establish: a) feasibility of training GPs in a communication intervention to solicit additional patient concerns early in the consultation, using specific lexical formulations (“do you have ‘any’ vs. ‘some’ other concerns?”) noting the... Read More about Findings from a feasibility study to improve GP elicitation of patient concerns in UK General Practice consultations.

Severity domains for quantifying the severity of Type 2 diabetes using primary care data and linked hospitalisation records from England (2018)
Presentation / Conference

Aims: Despite the increasing prevalence of Type 2 diabetes, which presents a significant burden on healthcare resources, there is no agreed validated UK measure to infer Type 2 diabetes severity from electronic health records (EHRs). This study aimed... Read More about Severity domains for quantifying the severity of Type 2 diabetes using primary care data and linked hospitalisation records from England.

A feasibility study for NOn-Traditional providers to support the management of Elderly People with Anxiety and Depression: The NOTEPAD study Protocol (2018)
Journal Article

Background Anxiety and depression are common among older people, with up to 20% reporting such symptoms, and the prevalence increases with co-morbid chronic physical health problems. Access to treatment for anxiety and depression in this population... Read More about A feasibility study for NOn-Traditional providers to support the management of Elderly People with Anxiety and Depression: The NOTEPAD study Protocol.

Evidence flowers: An innovative, visual method of presenting “best evidence” summaries to health professional and lay audiences (2018)
Journal Article

Background & Aims Barriers to dissemination and engagement with evidence pose a threat to implementing evidence-based medicine. Understanding, retention, and recall can be enhanced by visual presentation of information. The aim of this exploratory r... Read More about Evidence flowers: An innovative, visual method of presenting “best evidence” summaries to health professional and lay audiences.

What are the sources of stress and distress for general practitioners working in England? A qualitative study. (2018)
Journal Article

OBJECTIVES: This paper reports the sources of stress and distress experienced by general practitioners (GP) as part of a wider study exploring the barriers and facilitators to help-seeking for mental illness and burnout among this medical population.... Read More about What are the sources of stress and distress for general practitioners working in England? A qualitative study..

The INCLUDE study: INtegrating and improving Care for patients with infLammatory rheUmatological DisordErs in the community; identifying multimorbidity: Protocol for a pilot randomized controlled trial. (2018)
Journal Article

Background: Patients with inflammatory rheumatic conditions such as rheumatoid arthritis, polymyalgia rheumatica and ankylosing spondylitis are at increased risk of common comorbidities such as cardiovascular disease, osteoporosis and anxiety and dep... Read More about The INCLUDE study: INtegrating and improving Care for patients with infLammatory rheUmatological DisordErs in the community; identifying multimorbidity: Protocol for a pilot randomized controlled trial..

The feasibility and acceptability of a physical activity intervention for older people with chronic musculoskeletal pain: The iPOPP pilot trial protocol (2017)
Journal Article

INTRODUCTION: This pilot trial will inform the design and methods of a future full-scale randomized controlled trial (RCT) and examine the feasibility, acceptability and fidelity of the Increasing Physical activity in Older People with chronic Pain (... Read More about The feasibility and acceptability of a physical activity intervention for older people with chronic musculoskeletal pain: The iPOPP pilot trial protocol.

CollAborative care for Screen-Positive EldeRs with major depression (CASPER plus): a multicentred randomised controlled trial of clinical effectiveness and cost-effectiveness (2017)
Report

Background Depression in older adults is common and is associated with poor quality of life, increased morbidity and early mortality, and increased health and social care use. Collaborative care, a low-intensity intervention for depression that is s... Read More about CollAborative care for Screen-Positive EldeRs with major depression (CASPER plus): a multicentred randomised controlled trial of clinical effectiveness and cost-effectiveness.

Incidence, clinical management, and mortality risk following self harm among children and adolescents: cohort study in primary care (2017)
Journal Article

Objectives To examine temporal trends in sex and age specific incidence of self harm in children and adolescents, clinical management patterns, and risk of cause specific mortality following an index self harm episode at a young age.Design Population... Read More about Incidence, clinical management, and mortality risk following self harm among children and adolescents: cohort study in primary care.

Barriers, facilitators, and survival strategies for GPs seeking treatment for distress: a qualitative study. (2017)
Journal Article

BACKGROUND: GPs are under increasing pressure due to a lack of resources, a diminishing workforce, and rising patient demand. As a result, they may feel stressed, burnt out, anxious, or depressed. AIM: To establish what might help or hinder GPs exper... Read More about Barriers, facilitators, and survival strategies for GPs seeking treatment for distress: a qualitative study..

'If it's a medical issue I would have covered it by now': learning about fibromyalgia through the hidden curriculum: a qualitative study (2017)
Journal Article

BACKGROUND: Fibromyalgia syndrome (FMS) is a long-term condition that affects between 1 and 5% of the general population and lies within the spectrum of medically unexplained symptoms (MUS). FMS can be difficult to diagnose and is usually done so as... Read More about 'If it's a medical issue I would have covered it by now': learning about fibromyalgia through the hidden curriculum: a qualitative study.

Improving recognition of anxiety and depression in rheumatoid arthritis: a qualitative study in a community clinic (2017)
Journal Article

BACKGROUND: Comorbid anxiety and depression are common in patients with rheumatoid arthritis (RA) but are often under-recognised and treated, contributing to worse outcomes. National Institute for Health and Care Excellence (NICE) recommends that pat... Read More about Improving recognition of anxiety and depression in rheumatoid arthritis: a qualitative study in a community clinic.

Developing a community-based psycho-social intervention with older people and third sector workers for anxiety and depression: a qualitative study. (2017)
Journal Article

BACKGROUND: One-in-five people in the UK experience anxiety and/or depression in later life. However, anxiety and depression remain poorly detected in older people, particularly in those with chronic physical ill health. In the UK, a stepped care app... Read More about Developing a community-based psycho-social intervention with older people and third sector workers for anxiety and depression: a qualitative study..

Integrating case finding and initial management for osteoarthritis, anxiety and depression into routine primary care nurse-led long-term condition reviews: results from the enhance pilot trial (2017)
Journal Article

Background Co-morbid osteoarthritis (OA), anxiety and depression are undermanaged in primary care yet have significant impact on pain, disability and outcomes of other long-term conditions (LTCs). Objectives To test the feasibility and acceptabili... Read More about Integrating case finding and initial management for osteoarthritis, anxiety and depression into routine primary care nurse-led long-term condition reviews: results from the enhance pilot trial.

THU0614 Fidelity of an intervention to increase physical activity in older adults with chronic pain: analysis of audio-recorded consultations from the ipopp pilot trial (2017)
Presentation / Conference

Background Physical activity levels are low in people >65 years and those with chronic musculoskeletal pain, yet increased physical activity can lead to reduced pain. Walking is acceptable to older people with pain, but interventions to increase walk... Read More about THU0614 Fidelity of an intervention to increase physical activity in older adults with chronic pain: analysis of audio-recorded consultations from the ipopp pilot trial.

The effects of implementing a point-of-care electronic template to prompt routine anxiety and depression screening in patients consulting for osteoarthritis (the Primary Care Osteoarthritis Trial): A cluster randomised trial in primary care (2017)
Journal Article

BACKGROUND: This study aimed to evaluate whether prompting general practitioners (GPs) to routinely assess and manage anxiety and depression in patients consulting with osteoarthritis (OA) improves pain outcomes. METHODS AND FINDINGS: We conducted a... Read More about The effects of implementing a point-of-care electronic template to prompt routine anxiety and depression screening in patients consulting for osteoarthritis (the Primary Care Osteoarthritis Trial): A cluster randomised trial in primary care.

What do older people experiencing loneliness think about primary care or community based interventions to reduce loneliness?: a qualitative study in England (2017)
Journal Article

Loneliness in later life is a common problem with poor health outcomes. However, interventions to prevent or ameliorate loneliness have a weak evidence base. The views of older people experiencing or at risk of loneliness in the community are importa... Read More about What do older people experiencing loneliness think about primary care or community based interventions to reduce loneliness?: a qualitative study in England.

Musculoskeletal pain and co-morbid insomnia in adults; a population study of the prevalence and impact on restricted social participation. (2017)
Journal Article

BACKGROUND: Comorbidity is common in patients consulting in primary care. Musculoskeletal pain and insomnia each increase the risk of the other. Co-occurrence may pose an increased burden on well-being. However, the prevalence and impact of co-existi... Read More about Musculoskeletal pain and co-morbid insomnia in adults; a population study of the prevalence and impact on restricted social participation..

Feasibility of training practice nurses to deliver a psychosocial intervention within a collaborative care framework for people with depression and long-term conditions (2016)
Journal Article

Background Practice nurses (PNs) deliver much of the chronic disease management in primary care and have been highlighted as appropriately placed within the service to manage patients with long-term physical conditions (LTCs) and co-morbid depressio... Read More about Feasibility of training practice nurses to deliver a psychosocial intervention within a collaborative care framework for people with depression and long-term conditions.

Long-term cost-effectiveness of collaborative care (vs usual care) for people with depression and comorbid diabetes or cardiovascular disease: a Markov model informed by the COINCIDE randomised controlled trial (2016)
Journal Article

Objectives To evaluate the long-term cost-effectiveness of collaborative care (vs usual care) for treating depression in patients with diabetes and/or coronary heart disease (CHD). Setting 36 primary care general practices in North West England.... Read More about Long-term cost-effectiveness of collaborative care (vs usual care) for people with depression and comorbid diabetes or cardiovascular disease: a Markov model informed by the COINCIDE randomised controlled trial.

The implications of living with heart failure; the impact on everyday life, family support, co-morbidities and access to healthcare: a secondary qualitative analysis. (2016)
Journal Article

BACKGROUND: The aim of this study was to use secondary analysis to interrogate a qualitative data set to explore the experiences of patients living with heart failure. METHODS: The data-set comprised interviews with 11 patients who had participated i... Read More about The implications of living with heart failure; the impact on everyday life, family support, co-morbidities and access to healthcare: a secondary qualitative analysis..

Pre-eclampsia is associated with a twofold increase in diabetes: a systematic review and meta-analysis (2016)
Journal Article

Aims/hypothesis: Pre-eclampsia is a pregnancy-specific multi-system disorder and a state of physiological insulin resistance. Our aim is to systematically evaluate and quantify the evidence on the relationship between pre-eclampsia and the future ris... Read More about Pre-eclampsia is associated with a twofold increase in diabetes: a systematic review and meta-analysis.

Suicide risk in primary care patients diagnosed with a personality disorder: a nested case control study. (2016)
Journal Article

BACKGROUND: Personality disorder (PD) is associated with elevated suicide risk, but the level of risk in primary care settings is unknown. We assessed whether PD among primary care patients is linked with a greater elevation in risk as compared with... Read More about Suicide risk in primary care patients diagnosed with a personality disorder: a nested case control study..

Widespread pain and depression are key modifiable risk factors associated with reduced social participation in older adults: A prospective cohort study in primary care. (2016)
Journal Article

In older adults, reduced social participation increases the risk of poor health-related quality of life, increased levels of inflammatory markers and cardiovascular disease, and increased mortality. Older adults frequently present to primary care, wh... Read More about Widespread pain and depression are key modifiable risk factors associated with reduced social participation in older adults: A prospective cohort study in primary care..

A qualitative study of patient and professional perspectives of health care services for multiple sclerosis: implications for service development and policy (2016)
Journal Article

Multiple sclerosis (MS) is a chronic degenerative condition, with heterogeneous symptoms, and an unpredictable prognosis. Previous literature suggests patients' experiences of healthcare are unsatisfactory. Primary care may play a key role in the man... Read More about A qualitative study of patient and professional perspectives of health care services for multiple sclerosis: implications for service development and policy.

Meeting the mental health needs of people with multiple sclerosis: a qualitative study of patients and professionals (2016)
Journal Article

Purpose: To explore perspectives and experiences of people with multiple sclerosis (MS) and health care professionals of mental health support for MS in the UK. Method: 24 people with MS, 13 practice nurses, 12 general practitioners (GPs) and 9?MS... Read More about Meeting the mental health needs of people with multiple sclerosis: a qualitative study of patients and professionals.

Implementing resources to support the diagnosis and management of Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) in primary care: A qualitative study. (2016)
Journal Article

BACKGROUND: Previous research has highlighted that many GPs lack the confidence and knowledge to diagnose and manage people with CFS/ME. Following the development of an online training module for GPs, and an information pack and DVD for patients, thi... Read More about Implementing resources to support the diagnosis and management of Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) in primary care: A qualitative study..

Process and impact of patient involvement in a systematic review of shared decision making in primary care consultations (2016)
Journal Article

BACKGROUND: Patient and public involvement and engagement (PPIE) in systematic reviews remains uncommon, despite the policy imperative for patient involvement in research. The aim of this study was to investigate the process and impact of collaborati... Read More about Process and impact of patient involvement in a systematic review of shared decision making in primary care consultations.

Clinical effectiveness and cost-effectiveness of collaborative care for depression in UK primary care (CADET): a cluster randomised controlled trial (2016)
Report

Background Collaborative care is effective for depression management in the USA. There is little UK evidence on its clinical effectiveness and cost-effectiveness. Objective To determine the clinical effectiveness and cost-effectiveness of collab... Read More about Clinical effectiveness and cost-effectiveness of collaborative care for depression in UK primary care (CADET): a cluster randomised controlled trial.

Evaluating a complex model designed to increase access to high quality primary mental health care for under-served groups: a multi-method study. (2016)
Journal Article

BACKGROUND: Many people with mental distress are disadvantaged because care is not available or does not address their needs. In order to increase access to high quality primary mental health care for under-served groups, we created a model of care w... Read More about Evaluating a complex model designed to increase access to high quality primary mental health care for under-served groups: a multi-method study..

Mirtazapine added to selective serotonin reuptake inhibitors for treatment-resistant depression in primary care (MIR trial): study protocol for a randomised controlled trial (2016)
Journal Article

Background People with depression are usually managed in primary care and antidepressants are often the first-line treatment, but only one third of patients respond fully to a single antidepressant. This paper describes the protocol for a randomised... Read More about Mirtazapine added to selective serotonin reuptake inhibitors for treatment-resistant depression in primary care (MIR trial): study protocol for a randomised controlled trial.

Soliciting additional concerns in the primary care consultation and the utility of a brief communication intervention to aid solicitation: a qualitative study (2016)
Journal Article

Objective To investigate the perspectives of general practitioners (GPs) on the practice of soliciting additional concerns (ACs) and the acceptability and utility of two brief interventions (prompts) designed to aid the solicitation. Methods Eig... Read More about Soliciting additional concerns in the primary care consultation and the utility of a brief communication intervention to aid solicitation: a qualitative study.

‘I’m managing my diabetes between two worlds’: Beliefs and experiences of diabetes management in British South Asians on holiday in the East: a qualitative study (2015)
Journal Article

Background. Diabetes is disproportionately high among British South Asians compared to the general UK population. Whilst the migrant British South Asians group has received most attention on research related to diabetes management, little considerati... Read More about ‘I’m managing my diabetes between two worlds’: Beliefs and experiences of diabetes management in British South Asians on holiday in the East: a qualitative study.

Symptom perceptions and help-seeking behaviour prior to lung and colorectal cancer diagnoses: a qualitative study. (2015)
Journal Article

BACKGROUND: Lung and colorectal cancer are common and have high UK mortality rates. Early diagnosis is important in reducing cancer mortality, but the literature on lung and colorectal cancers suggests many people wait for a considerable time before... Read More about Symptom perceptions and help-seeking behaviour prior to lung and colorectal cancer diagnoses: a qualitative study..

Communicating Cardiovascular Disease Risk to People with Psoriasis: What Techniques do Practitioners Use? (2015)
Journal Article

Background Psoriasis can be associated with unhealthy lifestyle behaviours such as smoking, excess alcohol use and insufficient physical activity, consequently increasing cardiovascular disease (CVD) risk. Health care practitioners are expected to d... Read More about Communicating Cardiovascular Disease Risk to People with Psoriasis: What Techniques do Practitioners Use?.

Common and unique associated factors for medically unexplained chronic widespread pain and chronic fatigue. (2015)
Journal Article

OBJECTIVE: Chronic widespread pain and chronic fatigue share common associated factors but these associations may be explained by the presence of concurrent depression and anxiety. METHODS: We mailed questionnaires to a randomly selected sample of pe... Read More about Common and unique associated factors for medically unexplained chronic widespread pain and chronic fatigue..

'I should have taken that further' - missed opportunities during cardiovascular risk assessment in patients with psoriasis in UK primary care settings: a mixed-methods study. (2015)
Journal Article

BACKGROUND: Unhealthy lifestyle is common in psoriasis, contributing to worsening disease and increased cardiovascular disease (CVD) risk. CVD risk communication should improve patients' understanding of risk and risk-reducing behaviours; however, th... Read More about 'I should have taken that further' - missed opportunities during cardiovascular risk assessment in patients with psoriasis in UK primary care settings: a mixed-methods study..

Access to healthcare for long-term conditions in women involved in street-based prostitution: a qualitative study (2015)
Journal Article

Background Women involved in street-based prostitution (SBP) have well-documented health problems specific to their occupation, but access to care for other chronic health problems has not been explored. Primary care is seen as the optimal context t... Read More about Access to healthcare for long-term conditions in women involved in street-based prostitution: a qualitative study.

Illness beliefs and the sociocultural context of diabetes self-management in British South Asians: a mixed methods study (2015)
Journal Article

Background British South Asians have a higher incidence of diabetes and poorer health outcomes compared to the general UK population. Beliefs about diabetes are known to play an important role in self-management, yet little is known about the socioc... Read More about Illness beliefs and the sociocultural context of diabetes self-management in British South Asians: a mixed methods study.

046. Integrating Care for Joint Pain and Anxiety and Depression into Reviews for Long-Term Conditions: The Enhance Study (2015)
Journal Article

Joint pain and mental health problems are common and often co-exist with other long-term conditions (LTCs), but are under-detected and sub-optimally managed in primary care. The aim of the ENHANCE study is to develop and test the feasibility and acc... Read More about 046. Integrating Care for Joint Pain and Anxiety and Depression into Reviews for Long-Term Conditions: The Enhance Study.

Managing depression in people with multimorbidity: a qualitative evaluation of an integrated collaborative care model (2015)
Journal Article

Background Patients with comorbid depression and physical health problems have poorer outcomes compared with those with single long term conditions (LTCs), or multiple LTCs without depression. Primary care has traditionally struggled to provide inte... Read More about Managing depression in people with multimorbidity: a qualitative evaluation of an integrated collaborative care model.

Non-disclosure of chronic kidney disease in primary care and the limits of instrumental rationality in chronic illness self-management (2015)
Journal Article

Early detection of long term conditions is predicated on assumptions that lifestyle changes and medications can be used to reduce or manage the risk of condition progression. However, ambiguity remains about the nature and place of diagnostic disclos... Read More about Non-disclosure of chronic kidney disease in primary care and the limits of instrumental rationality in chronic illness self-management.

Integrated primary care for patients with mental and physical multimorbidity: cluster randomised controlled trial of collaborative care for patients with depression comorbid with diabetes or cardiovascular disease (2015)
Journal Article

Objective To test the effectiveness of an integrated collaborative care model for people with depression and long term physical conditions. Design Cluster randomised controlled trial. Setting 36 general practices in the north west of England.... Read More about Integrated primary care for patients with mental and physical multimorbidity: cluster randomised controlled trial of collaborative care for patients with depression comorbid with diabetes or cardiovascular disease.

Improving the care of people with long-term conditions in primary care: protocol for the ENHANCE pilot trial (2015)
Journal Article

Background: Long-term conditions (LTCs) are important determinants of quality of life and healthcare expenditure worldwide. Whilst multimorbidity is increasingly the norm in primary care, clinical guidelines and the delivery of care remain focused o... Read More about Improving the care of people with long-term conditions in primary care: protocol for the ENHANCE pilot trial.

PICO, PICOS and SPIDER: a comparison study of specificity and sensitivity in three search tools for qualitative systematic reviews (2014)
Journal Article

Background Qualitative systematic reviews are increasing in popularity in evidence based health care. Difficulties have been reported in conducting literature searches of qualitative research using the PICO search tool. An alternative search tool, e... Read More about PICO, PICOS and SPIDER: a comparison study of specificity and sensitivity in three search tools for qualitative systematic reviews.

CASPER plus (CollAborative Care in Screen-Positive EldeRs with major depressive disorder): study protocol for a randomised controlled trial. (2014)
Journal Article

Background Depression accounts for the greatest disease burden of all mental health disorders, contributes heavily to healthcare costs, and by 2020 is set to become the second largest cause of global disability. Although 10% to 16% of people aged 65... Read More about CASPER plus (CollAborative Care in Screen-Positive EldeRs with major depressive disorder): study protocol for a randomised controlled trial..

Understanding the challenges to implementing case management for people with dementia in English primary care using Normalisation Process Theory (2014)
Journal Article

Background Case management has been suggested as a way of improving the quality and cost-effectiveness of support for people with dementia. In this study we adapted and implemented a successful United States’ model of case management in primary care... Read More about Understanding the challenges to implementing case management for people with dementia in English primary care using Normalisation Process Theory.

'I wouldn't push that further because I don't want to lose her': a multiperspective qualitative study of behaviour change for long-term conditions in primary care. (2014)
Journal Article

BACKGROUND: Health outcomes for long-term conditions (LTCs) can be improved by lifestyle, dietary and condition management-related behaviour change. Primary care is an important setting for behaviour change work. Practitioners have identified barrier... Read More about 'I wouldn't push that further because I don't want to lose her': a multiperspective qualitative study of behaviour change for long-term conditions in primary care..

Implementation of a self-management support approach (WISE) across a health system: a process evaluation explaining what did and did not work for organisations, clinicians and patients. (2014)
Journal Article

BACKGROUND: Implementation of long-term condition management interventions rests on the notion of whole systems re-design, where incorporating wider elements of health care systems are integral to embedding effective and integrated solutions. However... Read More about Implementation of a self-management support approach (WISE) across a health system: a process evaluation explaining what did and did not work for organisations, clinicians and patients..

Effect of information and telephone-guided access to community support for people with chronic kidney disease: randomised controlled trial. (2014)
Journal Article

BACKGROUND: Implementation of self-management support in traditional primary care settings has proved difficult, encouraging the development of alternative models which actively link to community resources. Chronic kidney disease (CKD) is a common co... Read More about Effect of information and telephone-guided access to community support for people with chronic kidney disease: randomised controlled trial..

Depression predicts future emergency hospital admissions in primary care patients with chronic physical illness (2014)
Journal Article

Objective More than 15 million people currently suffer from a chronic physical illness in England. The objective of this study was to determine whether depression is independently associated with prospective emergency hospital admission in patients... Read More about Depression predicts future emergency hospital admissions in primary care patients with chronic physical illness.

A motivational intervention for patients with COPD in primary care: qualitative evaluation of a new practitioner role (2014)
Journal Article

BACKGROUND: Long-term conditions such as chronic obstructive pulmonary disease (COPD) are growing challenges for health services. Psychosocial co-morbidity is associated with poorer quality of life and greater use of health care in these patients but... Read More about A motivational intervention for patients with COPD in primary care: qualitative evaluation of a new practitioner role.

Implementing, embedding and integrating self-management support tools for people with long-term conditions in primary care nursing: a qualitative study (2014)
Journal Article

BACKGROUND: An implementation gap exists between policy aspirations for provision and the delivery of self-management support in primary care. An evidence based training and support package using a whole systems approach implemented as part of a rand... Read More about Implementing, embedding and integrating self-management support tools for people with long-term conditions in primary care nursing: a qualitative study.

The effectiveness of collaborative care for people with memory problems in primary care: results of the CAREDEM case management modelling and feasibility study. (2014)
Journal Article

Background People with dementia and their families need support in different forms, but currently services are often fragmented with variable quality of care. Case management offers a way of co-ordinating services along the care pathway and therefor... Read More about The effectiveness of collaborative care for people with memory problems in primary care: results of the CAREDEM case management modelling and feasibility study..

Overcoming the barriers to the diagnosis and management of chronic fatigue syndrome/ME in primary care: a meta synthesis of qualitative studies (2014)
Journal Article

Background The NICE guideline for Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) emphasises the need for an early diagnosis in primary care with management tailored to patient needs. However, GPs can be reluctant to make a diagnosis and... Read More about Overcoming the barriers to the diagnosis and management of chronic fatigue syndrome/ME in primary care: a meta synthesis of qualitative studies.

Telephone based self-management support by 'lay health workers' and 'peer support workers' to prevent and manage vascular diseases: a systematic review and meta-analysis (2013)
Journal Article

BACKGROUND: Improved prevention and management of vascular disease is a global priority. Non-health care professionals (such as, 'lay health workers' and 'peer support workers') are increasingly being used to offer telephone support alongside that of... Read More about Telephone based self-management support by 'lay health workers' and 'peer support workers' to prevent and manage vascular diseases: a systematic review and meta-analysis.

Using read codes to identify patients with irritable bowel syndrome in general practice: a database study (2013)
Journal Article

BACKGROUND: Estimates of the prevalence of irritable bowel syndrome (IBS) vary widely, and a large proportion of patients report having consulted their general practitioner (GP). In patients with new onset gastrointestinal symptoms in primary care it... Read More about Using read codes to identify patients with irritable bowel syndrome in general practice: a database study.

Better together? a naturalistic qualitative study of inter-professional working in collaborative care for co-morbid depression and physical health problems (2013)
Journal Article

Background Mental-physical multi-morbidities pose challenges for primary care services that traditionally focus on single diseases. Collaborative care models encourage inter-professional working to deliver better care for patients with multiple chro... Read More about Better together? a naturalistic qualitative study of inter-professional working in collaborative care for co-morbid depression and physical health problems.

Implementation of self management support for long term conditions in routine primary care settings: cluster randomised controlled trial (2013)
Journal Article

OBJECTIVE: To determine the effectiveness of an intervention to enhance self management support for patients with chronic conditions in UK primary care. DESIGN: Pragmatic, two arm, cluster randomised controlled trial. SETTING: General practices, serv... Read More about Implementation of self management support for long term conditions in routine primary care settings: cluster randomised controlled trial.