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Understanding current UK practice for the incidental identification of vertebral fragility fractures from CT scans: an expert elicitation study (2022)
Journal Article
Luetchens, S., Cootes, T., Payne, K., Dalal, G., Bromiley, P., & Kariki, E. (2022). Understanding current UK practice for the incidental identification of vertebral fragility fractures from CT scans: an expert elicitation study. Aging clinical and experimental research, 1909 - 1918. https://doi.org/10.1007/s40520-022-02124-w

Background There is an emerging interest in using automated approaches to enable the incidental identifcation of vertebral
fragility fractures (VFFs) on existing medical images visualising the spine.
Aim To quantify values, and the degree of uncer... Read More about Understanding current UK practice for the incidental identification of vertebral fragility fractures from CT scans: an expert elicitation study.

Ethical funding for trustworthy AI: proposals to address the responsibilities of funders to ensure that projects adhere to trustworthy AI practice (2022)
Journal Article
(2022). Ethical funding for trustworthy AI: proposals to address the responsibilities of funders to ensure that projects adhere to trustworthy AI practice. https://doi.org/10.1007/s43681-021-00069-w

<jats:title>Abstract</jats:title><jats:p>AI systems that demonstrate significant bias or lower than claimed accuracy, and resulting in individual and societal harms, continue to be reported. Such reports beg the question as to why such systems contin... Read More about Ethical funding for trustworthy AI: proposals to address the responsibilities of funders to ensure that projects adhere to trustworthy AI practice.

Humanising The Inhuman: Considering The Anthropomorphism Of Artificial Intelligence In Post-2010 Science Fiction Media (2022)
Journal Article
(2022). Humanising The Inhuman: Considering The Anthropomorphism Of Artificial Intelligence In Post-2010 Science Fiction Media. The Journal of Academic Development and Education, https://doi.org/10.21252/n4k1-c349

Anthropomorphism refers to the assignation of human characteristics to inanimate or non-human objects; whilst this concept is not new with relation to artificial intelligence in science fiction, post-2010 science fiction media provides an examination... Read More about Humanising The Inhuman: Considering The Anthropomorphism Of Artificial Intelligence In Post-2010 Science Fiction Media.

Deep neural network based date palm tree detection in drone imagery (2022)
Journal Article
Jintasuttisak, T., Edirisinghe, E., & Elbattay, A. (2022). Deep neural network based date palm tree detection in drone imagery. Computers and Electronics in Agriculture, 106560 - 106560. https://doi.org/10.1016/j.compag.2021.106560

Date palm trees are an important economic crop in the Arabian Peninsula, Middle East, and North Africa. Counting the numbers and determining the locations of date palm trees are important for predicting the date production and plantation management.... Read More about Deep neural network based date palm tree detection in drone imagery.

The effects of increased atmospheric reactive nitrogen deposition upon rates of biological nitrogen fixation in peatlands and temperate forests (2020)
Thesis
Saiz Val, E. (2020). The effects of increased atmospheric reactive nitrogen deposition upon rates of biological nitrogen fixation in peatlands and temperate forests. (Thesis). Keele University

Biological nitrogen fixation (BNF) is a microbial process that fixes atmospheric nitrogen (N2) gas into reactive, bioavailable forms (Nr). Naturally, lightning and BNF accounted for the entire Nr available for plant and microbial metabolic demands. H... Read More about The effects of increased atmospheric reactive nitrogen deposition upon rates of biological nitrogen fixation in peatlands and temperate forests.

Neuroevolution of Humanoids that Walk Further and Faster with Robust Gaits (2019)
Journal Article
Channon. (2019). Neuroevolution of Humanoids that Walk Further and Faster with Robust Gaits. Artificial Life, 543 - 550. https://doi.org/10.1162/isal_a_00219

Bipedal locomotion requires precise rhythm and balance. Here we demonstrate two fitness-function enhancements applied to OpenAI?s 3D Humanoid-v1 walking task using a replica of Salimans et al.?s evolution strategy (Salimans et al., 2017). The first e... Read More about Neuroevolution of Humanoids that Walk Further and Faster with Robust Gaits.

Structural characterisation of oligosaccharide recognition by surfactant protein D (2018)
Thesis
Littlejohn, J. R. (2018). Structural characterisation of oligosaccharide recognition by surfactant protein D. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/411451

Human surfactant protein D (hSP-D) is a C-type lectin and member of the collectin family that is involved in pathogen recognition as part of the innate immune response. Recognition occurs through the carbohydrate arrays on the surfaces of the pathoge... Read More about Structural characterisation of oligosaccharide recognition by surfactant protein D.

Synthesis and biological evaluation of three novel antimalarial series (2018)
Thesis
Tunstall, L. V. (2018). Synthesis and biological evaluation of three novel antimalarial series. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/411425

This research explored the optimisation of three novel antimalarial series based on the MMV compound leads shown below.
Extensive research began to optimise these potent hits through exploration of multiple functional group substitutions on two or... Read More about Synthesis and biological evaluation of three novel antimalarial series.

Chemical and morphological investigations of the Ontogenetic effects of Novel Psychoactive Substances on forensically important blowfly species (Diptera: Calliphoridae). (2018)
Thesis
Garrett, E. R. (2018). Chemical and morphological investigations of the Ontogenetic effects of Novel Psychoactive Substances on forensically important blowfly species (Diptera: Calliphoridae). (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/411392

Post Mortem Interval (PMI) estimation is a key concern of forensic entomology research. Numerous factors are recognized to affect these calculations, and have shown to potentially introduce error, leading to an incorrect time of death estimation. One... Read More about Chemical and morphological investigations of the Ontogenetic effects of Novel Psychoactive Substances on forensically important blowfly species (Diptera: Calliphoridae)..

Towards an understanding of amyloidogenesis: a structural and biophysical analysis of transthyretin (2018)
Thesis
Yee, A. W. (2018). Towards an understanding of amyloidogenesis: a structural and biophysical analysis of transthyretin. (Thesis). Keele University

Human transthyretin (TTR) is heavily implicated in a range of fatal amyloid diseases. The propensity to form amyloid varies between wild-type TTR and various mutants. In all cases this occurs by tetramer dissociation to a monomeric form, which in tur... Read More about Towards an understanding of amyloidogenesis: a structural and biophysical analysis of transthyretin.

Polymorphic transitions in cocoa butter studied by time resolved small-angle and wide-angle x-ray scattering using synchrotron radiation
Thesis
(2012). Polymorphic transitions in cocoa butter studied by time resolved small-angle and wide-angle x-ray scattering using synchrotron radiation

X-ray diffraction is a non-destructive technique which may be used to reveal information about the structure of materials, and is already a widely used tool in the study and determination of the polymorphic nature of cocoa butter and associated triac... Read More about Polymorphic transitions in cocoa butter studied by time resolved small-angle and wide-angle x-ray scattering using synchrotron radiation.

Linear and non-linear modelling of thermoacoustic instabilities in a laboratory burner
Thesis
(2014). Linear and non-linear modelling of thermoacoustic instabilities in a laboratory burner

Thermoacoustic instabilities are a mayor problem in industrial combustors, where they can lead to catastrophic hardware damage. An industrial gas turbine combustion chamber is a very complex and expensive system. Thus, a laboratory burner has been bu... Read More about Linear and non-linear modelling of thermoacoustic instabilities in a laboratory burner.

An investigation into the fitness and mating competitiveness of laboratory and transgenic strains of Anopheles gambiae sensu stricto
Thesis
(2013). An investigation into the fitness and mating competitiveness of laboratory and transgenic strains of Anopheles gambiae sensu stricto

Malaria is a deadly parasitic disease of humans spread through the bite of Anopheles spp. mosquitoes. Current control methods for the disease are broadly effective, but the spread of insecticide resistance in the principle Anopheline vectors of the d... Read More about An investigation into the fitness and mating competitiveness of laboratory and transgenic strains of Anopheles gambiae sensu stricto.

Volatile biomarkers emitted by cell cultures: headspace analysis using selected ion flow tube mass spectrometry, SIFT-MS
Thesis
(2013). Volatile biomarkers emitted by cell cultures: headspace analysis using selected ion flow tube mass spectrometry, SIFT-MS

The work presented in this thesis was initiated in order to develop a non-invasive real-time gas phase analytical technique, based on selected ion flow tube mass spectrometry (SIFT-MS), for monitoring the progression of human cell cultures and the de... Read More about Volatile biomarkers emitted by cell cultures: headspace analysis using selected ion flow tube mass spectrometry, SIFT-MS.

Neutrons reveal the structure and dynamics of osteopontin phosphopeptides and nanocluster formation
Thesis
(2017). Neutrons reveal the structure and dynamics of osteopontin phosphopeptides and nanocluster formation

In bovine milk the highly phosphorylated cleavage fragment of osteopontin (OPN1-149) is capable of stabilising high concentrations of calcium phosphate ions by formation of calcium phosphate nanoclusters (CPN). Here OPN1-149 isolated from bovine milk... Read More about Neutrons reveal the structure and dynamics of osteopontin phosphopeptides and nanocluster formation.

Simultaneous incremental neuroevolution of motor control, navigation and object manipulation in 3D virtual creatures
Thesis
Stanton, A. J. (2017). Simultaneous incremental neuroevolution of motor control, navigation and object manipulation in 3D virtual creatures

There have been numerous attempts to develop 3D virtual agents by applying evolutionary processes to populations that exist in a realistic physical simulation. Whilst often contributing useful knowledge, no previous work has demonstrated the capacity... Read More about Simultaneous incremental neuroevolution of motor control, navigation and object manipulation in 3D virtual creatures.