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Analysis of the use of human remains as teaching materials in higher education: examining differing opinions between population subgroups (2023)
Journal Article
Goodison, G. A., & Aris, C. (2023). Analysis of the use of human remains as teaching materials in higher education: examining differing opinions between population subgroups. European Journal of Anatomy, 27(4), 503-516. https://doi.org/10.52083/EWHY1593

Human components have been used as teaching resources for centuries. This study aimed to investigate the ethics and practicality surrounding this resource by analysing the opinions of students and professionals with exposure to human remains.Three qu... Read More about Analysis of the use of human remains as teaching materials in higher education: examining differing opinions between population subgroups.

Functional Analysis of Anuran Pelvic and Thigh Anatomy Using Musculoskeletal Modelling of Phlyctimantis maculatus (2022)
Journal Article
Collings, A. (2022). Functional Analysis of Anuran Pelvic and Thigh Anatomy Using Musculoskeletal Modelling of Phlyctimantis maculatus. Frontiers in Bioengineering and Biotechnology, https://doi.org/10.3389/fbioe.2022.806174

<jats:p>Using their abundant musculature, frogs are able to exhibit outstanding behavioural versatility. However, understanding the dynamic motion of their 30 + hindlimb muscles, with multi-joint action, and curved pathways, is challenging. This is p... Read More about Functional Analysis of Anuran Pelvic and Thigh Anatomy Using Musculoskeletal Modelling of Phlyctimantis maculatus.

Impact of iodine concentration and scan parameters on image quality, contrast enhancement and radiation dose in thoracic CT (2020)
Journal Article
(2020). Impact of iodine concentration and scan parameters on image quality, contrast enhancement and radiation dose in thoracic CT. European Radiology Experimental, https://doi.org/10.1186/s41747-020-00184-z

<jats:title>Abstract</jats:title> <jats:sec> <jats:title>Background</jats:title> <jats:p>We investigated the impact of varying contrast medium (CM) densities and x-ray tube potentials on contrast enhancement (CE), image quality and radiation dose in... Read More about Impact of iodine concentration and scan parameters on image quality, contrast enhancement and radiation dose in thoracic CT.

Establishing a minimum PMI for bone sun bleaching in a UK environment with a controlled desert-simulated comparison (2020)
Journal Article
Stokes, S., Greenwood, C., & Márquez-Grant, N. (2020). Establishing a minimum PMI for bone sun bleaching in a UK environment with a controlled desert-simulated comparison. International Journal of Legal Medicine, 134, 2297–2306. https://doi.org/10.1007/s00414-020-02385-y

Microenvironments play a significant part in understanding the post-mortem interval in forensic taphonomy. Recently, the value of weathering factors in relation to obtaining a PMI has been investigated further. In this study, observations were made t... Read More about Establishing a minimum PMI for bone sun bleaching in a UK environment with a controlled desert-simulated comparison.

Geophysical monitoring of simulated homicide burials for forensic investigations (2020)
Journal Article
Pringle, J., Stimpson, I., Wisniewski, K., Davenward, B., Heaton, V., Mirosch, N., …Jervis, J. (2020). Geophysical monitoring of simulated homicide burials for forensic investigations. Scientific reports, 10, Article 7544. https://doi.org/10.1038/s41598-020-64262-3

Finding hidden bodies, believed to have been murdered and buried, is problematic, expensive in terms of human resource and currently has low success rates for law enforcement agencies. Here we present, for the first time, ten years of multidisciplina... Read More about Geophysical monitoring of simulated homicide burials for forensic investigations.

Prediction models for diagnosis and prognosis of covid-19 infection: systematic review and critical appraisal. (2020)
Journal Article
(2020). Prediction models for diagnosis and prognosis of covid-19 infection: systematic review and critical appraisal. BMJ, https://doi.org/10.1136/bmj.m1328

OBJECTIVE: To review and critically appraise published and preprint reports of prediction models for diagnosing coronavirus disease 2019 (covid-19) in patients with suspected infection, for prognosis of patients with covid-19, and for detecting peopl... Read More about Prediction models for diagnosis and prognosis of covid-19 infection: systematic review and critical appraisal..

Development, synthesis and biological investigation of a novel class of potent PC-PLC inhibitors. (2020)
Journal Article
Reynisson. (2020). Development, synthesis and biological investigation of a novel class of potent PC-PLC inhibitors. European Journal of Medicinal Chemistry, https://doi.org/10.1016/j.ejmech.2020.112162

Phospholipases are enzymes that are involved in the hydrolysis of acyl and phosphate esters of phospholipids, generating secondary messengers that have implications in various cellular processes including proliferation, differentiation and motility.... Read More about Development, synthesis and biological investigation of a novel class of potent PC-PLC inhibitors..

Injected human umbilical cord-derived mesenchymal stromal cells do not appear to elicit an inflammatory response in a murine model of osteoarthritis (2020)
Journal Article
Perry, J., McCarthy, H., Bou-Gharios, G., van't Hof, R., Milner, P., Mennan, C., & Roberts, S. (2020). Injected human umbilical cord-derived mesenchymal stromal cells do not appear to elicit an inflammatory response in a murine model of osteoarthritis. Osteoarthritis and Cartilage Open, 2(2), 100044 - 100044. https://doi.org/10.1016/j.ocarto.2020.100044

Objective This study investigated the effect of hUC-MSCs on osteoarthritis (OA) progression in a xenogeneic model. Design Male, 10 week-old C57Bl/6 mice underwent sham surgery (n=15) or partial medial meniscectomy (PMM;n=76). 5x105 hUC-MSCs (from 3 d... Read More about Injected human umbilical cord-derived mesenchymal stromal cells do not appear to elicit an inflammatory response in a murine model of osteoarthritis.

Scoliosis in paediatric onset spinal cord injuries. (2020)
Journal Article
Kuiper. (2020). Scoliosis in paediatric onset spinal cord injuries. Spinal Cord, https://doi.org/10.1038/s41393-020-0418-6

STUDY DESIGN: This is a retrospective longitudinal review. OBJECTIVE: The purpose of this review was to identify predictors of developing clinical scoliosis and compare between traumatic and neurological aetiologies of SCI. SETTING: This study was co... Read More about Scoliosis in paediatric onset spinal cord injuries..

Obstetrics and Gynecological History (2020)
Journal Article
Park, K., Wu, P., & Gulati, M. (2020). Obstetrics and Gynecological History. JACC: Case Reports, 2(1), 161 - 163. https://doi.org/10.1016/j.jaccas.2019.11.035

Atherosclerotic cardiovascular disease (ASCVD) remains a significant cause of morbidity and mortality in women, with event rates rising particularly in young women. Women are disproportionately affected by traditional cardiovascular (CV) risk factors... Read More about Obstetrics and Gynecological History.

Improving predictor selection for injury modelling methods in male footballers (2020)
Journal Article
Philp, F., Al-shallawi, A., Kyriacou, T., Blana, D., & Pandyan, A. (2020). Improving predictor selection for injury modelling methods in male footballers. BMJ Open Sport & Exercise Medicine, 6(1), e000634 - e000634. https://doi.org/10.1136/bmjsem-2019-000634

Objectives
This objective of this study was to evaluate whether combining existing methods of elastic net for zero-inflated Poisson and zero-inflated Poisson regression methods could improve real-life applicability of injury prediction models in foo... Read More about Improving predictor selection for injury modelling methods in male footballers.

Characterization of soft tissue tumours with ultrasound, shear wave elastography and MRI (2020)
Journal Article
Cool. (2020). Characterization of soft tissue tumours with ultrasound, shear wave elastography and MRI. Skeletal Radiology, 49, 869–881. https://doi.org/10.1007/s00256-019-03363-1

OBJECTIVE: To predict accurately whether a soft tissue mass was benign or malignant and to characterize its type using ultrasound, shear wave elastography and MRI. We hypothesized that with the addition of shear wave elastography, it would be possibl... Read More about Characterization of soft tissue tumours with ultrasound, shear wave elastography and MRI.

Silicone 3D Printing: Process Optimization, Product Biocompatibility, and Reliability of Silicone Meniscus Implants (2019)
Journal Article
Luis, E., Pan, H. M., Sing, S. L., Bastola, A. K., Goh, G. L., Goh, G. D., …Yeong, W. Y. (2019). Silicone 3D Printing: Process Optimization, Product Biocompatibility, and Reliability of Silicone Meniscus Implants. 3D Printing and Additive Manufacturing, 6(6), 319 - 332. https://doi.org/10.1089/3dp.2018.0226

A novel custom-made 3D silicone printer and two-part Ecoflex silicone resins were used to 3D-print standard-shaped silicone coupon and irregular-shaped meniscus structures via a heat-cured extrusion-based method. This paper is segmented into 3 parts:... Read More about Silicone 3D Printing: Process Optimization, Product Biocompatibility, and Reliability of Silicone Meniscus Implants.

The effect of high glucose on lipid metabolism in the human placenta (2019)
Journal Article
Hulme. (2019). The effect of high glucose on lipid metabolism in the human placenta. Scientific reports, https://doi.org/10.1038/s41598-019-50626-x

Diabetes mellitus (DM) during pregnancy can result in fetal overgrowth, likely due to placental dysfunction, which has health consequences for the infant. Here we test our prediction from previous work using a placental cell line that high glucose co... Read More about The effect of high glucose on lipid metabolism in the human placenta.

Cuticular Hydrocarbon Analysis in Forensic Entomology: A Review (2019)
Journal Article
Shemilt. (2019). Cuticular Hydrocarbon Analysis in Forensic Entomology: A Review. Archaeological and Environmental Forensic Science, 127 - 138. https://doi.org/10.1558/aefs.36241

Blowflies are the first inhabitants of decomposing remains and are therefore of forensic relevance for post mortem interval estimations. Forensic entomology is becoming widely accepted as a branch of forensic science and is being utilised more within... Read More about Cuticular Hydrocarbon Analysis in Forensic Entomology: A Review.

The microRNA-183/96/182 Cluster is Essential for Stereociliary Bundle Formation and Function of Cochlear Sensory Hair Cells (2018)
Journal Article
Geng, R., Furness, D. N., Muraleedharan, C. K., Zhang, J., Dabdoub, A., Lin, V., & Xu, S. (2018). The microRNA-183/96/182 Cluster is Essential for Stereociliary Bundle Formation and Function of Cochlear Sensory Hair Cells. Scientific reports, 8, 18022 - ?. https://doi.org/10.1038/s41598-018-36894-z

The microRNA (miR)-183/96/182 cluster plays important roles in the development and functions of sensory organs, including the inner ear. Point-mutations in the seed sequence of miR-96 result in non-syndromic hearing loss in both mice and humans. Howe... Read More about The microRNA-183/96/182 Cluster is Essential for Stereociliary Bundle Formation and Function of Cochlear Sensory Hair Cells.

Effect of diet and physical activity based interventions in pregnancy on gestational weight gain and pregnancy outcomes: meta-analysis of individual participant data from randomised trials (2017)
Journal Article
(2017). Effect of diet and physical activity based interventions in pregnancy on gestational weight gain and pregnancy outcomes: meta-analysis of individual participant data from randomised trials. BMJ, https://doi.org/10.1136/bmj.j3991

Objective To synthesise the evidence on the overall and differential effects of interventions based on diet and physical activity during pregnancy, primarily on gestational weight gain and maternal and offspring composite outcomes, according to women... Read More about Effect of diet and physical activity based interventions in pregnancy on gestational weight gain and pregnancy outcomes: meta-analysis of individual participant data from randomised trials.