Optimising physiotherapy treatment for people with lateral elbow tendinopathy: development and pilot/feasibility testing of an evidence-based treatment approach (2024)
Thesis
Bateman, M. (2024). Optimising physiotherapy treatment for people with lateral elbow tendinopathy: development and pilot/feasibility testing of an evidence-based treatment approach. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/853496

Background: There are a wide range of physiotherapy treatment options for people with lateral elbow tendinopathy (LET), however previous studies have reported inconsistent approaches to treatment and a lack of evidence demonstrating clinical effectiv... Read More about Optimising physiotherapy treatment for people with lateral elbow tendinopathy: development and pilot/feasibility testing of an evidence-based treatment approach.

Using Twitter to mobilise knowledge for First Contact Physiotherapists - A qualitative study (2023)
Thesis
Campbell, L. H. (2023). Using Twitter to mobilise knowledge for First Contact Physiotherapists - A qualitative study. (Thesis). Keele University

Background - First Contact Physiotherapists (FCPs) specialise in supporting people who consult with musculoskeletal conditions in National Health Service primary care. Cited FCP role challenges include professional isolation, time demands and changin... Read More about Using Twitter to mobilise knowledge for First Contact Physiotherapists - A qualitative study.

Electroactive Scaffolds to Improve Neural Stem Cell Therapy for Spinal Cord Injury (2022)
Journal Article
Mutepfa, A. R., Hardy, J. G., & Adams, C. F. (2022). Electroactive Scaffolds to Improve Neural Stem Cell Therapy for Spinal Cord Injury. Frontiers in Medical Technology, 4, 693438. https://doi.org/10.3389/fmedt.2022.693438

Spinal cord injury (SCI) is a serious condition caused by damage to the spinal cord through trauma or disease, often with permanent debilitating effects. Globally, the prevalence of SCI is estimated between 40 to 80 cases per million people per year.... Read More about Electroactive Scaffolds to Improve Neural Stem Cell Therapy for Spinal Cord Injury.

Outcomes following Percutaneous Coronary Intervention in Renal Transplant Recipients; A Binational collaborative analysis (2021)
Journal Article
Mamas, & Rashid. (2021). Outcomes following Percutaneous Coronary Intervention in Renal Transplant Recipients; A Binational collaborative analysis. Mayo Clinic Proceedings, 363-376. https://doi.org/10.1016/j.mayocp.2020.04.045

Objective: We sought to investigate the clinical and procedural characteristics in patients with a history of Renal Transplant (RT) and compare the outcomes with non-RT patients in two national cohorts of patients undergoing percutaneous coronary int... Read More about Outcomes following Percutaneous Coronary Intervention in Renal Transplant Recipients; A Binational collaborative analysis.

Normative performance values of modified Star Excursion Balance Test and Limb Symmetry in female adolescent footballers (2020)
Journal Article
(2020). Normative performance values of modified Star Excursion Balance Test and Limb Symmetry in female adolescent footballers. Translational Sports Medicine, 328-336. https://doi.org/10.1002/tsm2.146

To establish normative performance values for the modified Star Excursion Balance Test (mSEBT) and derived Limb Symmetry Index (LSI) scores in non-injured female adolescent footballers, to and identity whether there is a relationship between the afor... Read More about Normative performance values of modified Star Excursion Balance Test and Limb Symmetry in female adolescent footballers.

Trends in Incidence and Prevalence of Osteoarthritis in the United Kingdom: Findings from the Clinical Practice Research Datalink (CPRD) (2020)
Journal Article
Mallen. (2020). Trends in Incidence and Prevalence of Osteoarthritis in the United Kingdom: Findings from the Clinical Practice Research Datalink (CPRD). Osteoarthritis and Cartilage, 792-801. https://doi.org/10.1016/j.joca.2020.03.004

Objective: This study aimed to explore the incidence and prevalence of OA in the UK in 2017 and their trends from 1997 to 2017 using a large nationally representative primary care database.

Design: The UK Clinical Practice Research Datalink (CPRD)... Read More about Trends in Incidence and Prevalence of Osteoarthritis in the United Kingdom: Findings from the Clinical Practice Research Datalink (CPRD).

Obstetrics and Gynecological History (2020)
Journal Article
Park, K., Wu, P., & Gulati, M. (2020). Obstetrics and Gynecological History. JACC: Case Reports, 2(1), 161 - 163. https://doi.org/10.1016/j.jaccas.2019.11.035

Atherosclerotic cardiovascular disease (ASCVD) remains a significant cause of morbidity and mortality in women, with event rates rising particularly in young women. Women are disproportionately affected by traditional cardiovascular (CV) risk factors... Read More about Obstetrics and Gynecological History.

Improving predictor selection for injury modelling methods in male footballers (2020)
Journal Article
Philp, F., Al-shallawi, A., Kyriacou, T., Blana, D., & Pandyan, A. (2020). Improving predictor selection for injury modelling methods in male footballers. BMJ Open Sport & Exercise Medicine, 6(1), e000634 - e000634. https://doi.org/10.1136/bmjsem-2019-000634

Objectives
This objective of this study was to evaluate whether combining existing methods of elastic net for zero-inflated Poisson and zero-inflated Poisson regression methods could improve real-life applicability of injury prediction models in foo... Read More about Improving predictor selection for injury modelling methods in male footballers.

Characterization of soft tissue tumours with ultrasound, shear wave elastography and MRI (2020)
Journal Article
Cool. (2020). Characterization of soft tissue tumours with ultrasound, shear wave elastography and MRI. Skeletal Radiology, 49, 869–881. https://doi.org/10.1007/s00256-019-03363-1

OBJECTIVE: To predict accurately whether a soft tissue mass was benign or malignant and to characterize its type using ultrasound, shear wave elastography and MRI. We hypothesized that with the addition of shear wave elastography, it would be possibl... Read More about Characterization of soft tissue tumours with ultrasound, shear wave elastography and MRI.

The impact of pelvic lateral rotation on hindlimb kinematics and stride length in the red-legged running frog, Kassina maculata (2019)
Journal Article
Collings, A. J., Porro, L. B., Hill, C., & Richards, C. T. (2019). The impact of pelvic lateral rotation on hindlimb kinematics and stride length in the red-legged running frog, Kassina maculata. Royal Society Open Science, 6(5), Article 190060. https://doi.org/10.1098/rsos.190060

Some frog species, such as Kassina maculata (red-legged running frog), use an asynchronous walking/running gait as their primary locomotor mode. Prior comparative anatomy work has suggested that lateral rotation of the pelvis improves walking perform... Read More about The impact of pelvic lateral rotation on hindlimb kinematics and stride length in the red-legged running frog, Kassina maculata.

The microRNA-183/96/182 Cluster is Essential for Stereociliary Bundle Formation and Function of Cochlear Sensory Hair Cells (2018)
Journal Article
Geng, R., Furness, D. N., Muraleedharan, C. K., Zhang, J., Dabdoub, A., Lin, V., & Xu, S. (2018). The microRNA-183/96/182 Cluster is Essential for Stereociliary Bundle Formation and Function of Cochlear Sensory Hair Cells. Scientific reports, 8, 18022 - ?. https://doi.org/10.1038/s41598-018-36894-z

The microRNA (miR)-183/96/182 cluster plays important roles in the development and functions of sensory organs, including the inner ear. Point-mutations in the seed sequence of miR-96 result in non-syndromic hearing loss in both mice and humans. Howe... Read More about The microRNA-183/96/182 Cluster is Essential for Stereociliary Bundle Formation and Function of Cochlear Sensory Hair Cells.

Human Skeletal Muscle Possesses an Epigenetic Memory of Hypertrophy (2018)
Journal Article
(2018). Human Skeletal Muscle Possesses an Epigenetic Memory of Hypertrophy. Scientific reports, 8:1898 - 8:1898. https://doi.org/10.1038/s41598-018-20287-3

It is unknown if adult human skeletal muscle has an epigenetic memory of earlier encounters with growth. We report, for the first time in humans, genome-wide DNA methylation (850,000?CpGs) and gene expression analysis after muscle hypertrophy (loadin... Read More about Human Skeletal Muscle Possesses an Epigenetic Memory of Hypertrophy.

Structure: activity relationships for the cytoprotective effects of epoxyeicosatrienoic acids (EETs) and their corresponding diols against palmitate-induced lipotoxicity in BRIN-BD11 cells (2017)
Journal Article
(2017). Structure: activity relationships for the cytoprotective effects of epoxyeicosatrienoic acids (EETs) and their corresponding diols against palmitate-induced lipotoxicity in BRIN-BD11 cells. Diabetic Medicine, 26-26

Effects of transthyretin on thyroxine and ß-amyloid removal from cerebrospinal fluid in mice. (2016)
Journal Article
Chen, R., Chen, C. P., & Preston, J. E. (2016). Effects of transthyretin on thyroxine and ß-amyloid removal from cerebrospinal fluid in mice. Clinical and Experimental Pharmacology and Physiology, 43(9), 844-850. https://doi.org/10.1111/1440-1681.12598

Transthyretin (TTR) is a binding protein for the thyroid hormone thyroxine (T4 ), retinol and ß-amyloid peptide. TTR aids the transfer of T4 from the blood to the cerebrospinal fluid (CSF), but also prevents T4 loss from the blood-CSF barrier. It is... Read More about Effects of transthyretin on thyroxine and ß-amyloid removal from cerebrospinal fluid in mice..

Flourescent, online monitoring of PLGA degradation for regenerative medicine applications (2016)
Journal Article
Yang. (2016). Flourescent, online monitoring of PLGA degradation for regenerative medicine applications. RSC advances, 44364 - 44370. https://doi.org/10.1039/C6RA04690H

Degradable polymers such as poly(lactic-co-glycolic acid) (PLGA) are frequently chosen for tissue engineering, due to their ease of production, controllable degradation rates and Food and Drug Administration (FDA) approval. Within tissue engineering... Read More about Flourescent, online monitoring of PLGA degradation for regenerative medicine applications.

The vacuolar ATPase subunit E controls apoptosis and is down-regulated in breast cancer (2015)
Presentation / Conference
Mohammed, S., & Mourtada-Maarabouni, M. (2015, November). The vacuolar ATPase subunit E controls apoptosis and is down-regulated in breast cancer. Poster presented at 11th NCRI Cancer Conference, Liverpool

Background
Vacuolar H+-ATPase (v-ATPase) is a large multisubunit proton pump that mediates the acidification of many intracellular compartments. Previous studies have strongly implicated v-ATPase in carcinogenesis and tumour progression and indicat... Read More about The vacuolar ATPase subunit E controls apoptosis and is down-regulated in breast cancer.

A role for the long non-coding RNA growth arrest specific transcript 5 (GAS5) in cytokine-induced beta cell death (2015)
Journal Article
(2015). A role for the long non-coding RNA growth arrest specific transcript 5 (GAS5) in cytokine-induced beta cell death. Diabetic Medicine, 39 - 39. https://doi.org/10.1111/dme.12668

Pro-inflammatory cytokines are known inducers of beta cell death in the pathogenesis of Type 1 diabetes and mediate their effects through the perturbation of multiple regulatory gene networks. GAS5, a long non-coding RNA whose expression negatively c... Read More about A role for the long non-coding RNA growth arrest specific transcript 5 (GAS5) in cytokine-induced beta cell death.

Large, binge-type meals of high fat diet change feeding behaviour and entrain food anticipatory activity in mice (2014)
Journal Article
Bake, T., Murphy, M., Morgan, D., & Mercer, J. (2014). Large, binge-type meals of high fat diet change feeding behaviour and entrain food anticipatory activity in mice. Appetite, 77, 60 - 71. https://doi.org/10.1016/j.appet.2014.02.020

Male C57BL/6 mice fed ad libitum on control diet but allowed access to a palatable high fat diet (HFD) for 2?h a day during the mid-dark phase rapidly adapt their feeding behaviour and can consume nearly 80% of their daily caloric intake during this... Read More about Large, binge-type meals of high fat diet change feeding behaviour and entrain food anticipatory activity in mice.

Structural studies of a2-macroglobulin from the horseshoe crab Limulus polyphemus
Thesis
Nicosia, M. (2016). Structural studies of a2-macroglobulin from the horseshoe crab Limulus polyphemus

This work is focused on structural studies of the innate immune protein a2-macroglobulin from the horseshoe crab, Limulus Polyphemus, using crystallography and structure prediction software to reveal clues about the structure and function of this key... Read More about Structural studies of a2-macroglobulin from the horseshoe crab Limulus polyphemus.

Severity and progression of hand pain and functional difficulty: a prospective cohort study in community-dwelling older adults with hand pain
Thesis
Nicholls, E. E. (2016). Severity and progression of hand pain and functional difficulty: a prospective cohort study in community-dwelling older adults with hand pain

Background
Hand problems are common in older adults causing pain and disruption to daily living. Understanding prognosis of such problems is therefore important to provide information on likely symptom course and to target treatment to those in most... Read More about Severity and progression of hand pain and functional difficulty: a prospective cohort study in community-dwelling older adults with hand pain.