BACKGROUND: Perinatal depression (PND) describes depression experienced by parents during pregnancy or in the first year after a baby is born. The EQ-5D instrument (a generic measure of health status) is not often collected in perinatal research, how... Read More about Generating EQ-5D-3L health utility scores from the Edinburgh Postnatal Depression Scale: a perinatal mapping study.
Premenstrual syndrome (PMS) is a distressing psychological and somatic disorder of unidentified aetiology occurring during the luteal phase of the menstrual cycle. This thesis includes systematic reviews of the published literature on the therapeutic... Read More about Systematic reviews of the management of premenstrual disorder through the elimination of ovulation.
Background Despite guidelines recommending the evaluation of adverse pregnancy outcomes (APOs) as a part of the atherosclerotic cardiovascular disease (ASCVD) risk assessment in women, there is limited awareness of this issue in healthcare professio... Read More about Health Care Professional's Knowledge of Pregnancy Complications and Women's Cardiovascular Health: An International Study Utilizing Social Media.
Objective To update the systematic review which informed the National Institute for Health and Care Excellence guideline “Inducing Labour” (NG207), including additional data and analyses, and comparison with a recent individual patient data analysis... Read More about Timing of induction of labour in the prevention of prolonged pregnancy: Systematic review with meta‐analysis.
Diabetes mellitus (pregestational (PDM) and gestational (GDM)) is associated with adverse pregnancy outcomes (APOs). However, studies exploring the association of APOs with maternal glycemia among women without PDM/GDM are limited. We utilized data f... Read More about Maternal Glycemic Spectrum and Adverse Pregnancy and Perinatal Outcomes in a Multiracial US Cohort.
Preterm prelabour rupture of membranes is the leading cause of preterm birth and its associated infant mortality and morbidity. However, its underlying mechanism remains unknown. We utilized two novel biomechanical assessment techniques, ball indenta... Read More about New approaches suggest term and preterm human fetal membranes may have distinct biomechanical properties..
Preterm prelabour rupture of membranes is the leading cause of preterm birth and its associated infant mortality and morbidity. However, its underlying mechanism remains unknown. We utilized two novel biomechanical assessment techniques, ball indenta... Read More about New approaches suggest term and preterm human fetal membranes may have distinct biomechanical properties.
In‐Hospital Complications in Pregnancies Conceived by Assisted Reproductive Technology (2022)
Background Assisted reproductive technology (ART) has emerged as a common treatment option for infertility, a problem that affects an estimated 48 million couples worldwide. Advancing maternal age with increasing prepregnancy cardiovascular risk fact... Read More about In‐Hospital Complications in Pregnancies Conceived by Assisted Reproductive Technology.
To investigate the role of DNA mismatch repair status (MMR) in survival of endometrioid endometrial cancer in Hong Kong Chinese women and its correlation to clinical prognostic factors, 238 patients with endometrioid endometrial cancer were included.... Read More about Long-Term Survival and Clinicopathological Implications of DNA Mismatch Repair Status in Endometrioid Endometrial Cancers in Hong Kong Chinese Women..
The Fourth Trimester: Pregnancy as a Predictor of Cardiovascular Disease (2021)
Pregnancy identifies women who may be at a greater risk of cardiovascular disease (CVD), based on the development of adverse pregnancy outcomes (APOs), and may identify women who may benefit from atherosclerotic CVD (ASCVD) risk reduction efforts. AP... Read More about The Fourth Trimester: Pregnancy as a Predictor of Cardiovascular Disease.
External validation of prognostic models to predict stillbirth using the International Prediction of Pregnancy Complications (IPPIC) Network database: an individual participant data meta-analysis. (2021)
OBJECTIVE: Stillbirth is a potentially preventable complication of pregnancy. Identifying women at risk can guide decisions on closer surveillance or timing of birth to prevent fetal death. Prognostic models have been developed to predict the risk of... Read More about External validation of prognostic models to predict stillbirth using the International Prediction of Pregnancy Complications (IPPIC) Network database: an individual participant data meta-analysis..
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Objective Accurate diagnosis of polycystic ovarian syndrome (PCOS) enables clinical interventions/cardiometabolic risk factor management. Diagnosis can take over 2 years and multiple clinician contacts. We examined patterns of PCOS-associated biochem... Read More about Investigation of polycystic ovarian syndrome: variation in practice and impact on the speed of diagnosis.
BACKGROUND: Stillbirth prevention is an international priority - risk prediction models could individualise care and reduce unnecessary intervention, but their use requires evaluation. OBJECTIVES: To identify risk prediction models for stillbirth, an... Read More about Can risk prediction models help us individualise stillbirth prevention? A systematic review and critical appraisal of published risk models..
Hypertensive disorders of pregnancy and impact on in-hospital cardio-obstetric outcomes (2020)
Presentation / Conference
Background Stroke is a serious complication of hypertensive disorders of pregnancy (HDP), with potentially severe and long-term sequelae. However, the temporal trends, predictors and outcomes of stroke in women with HDP at delivery remain unknown.... Read More about Temporal Trends in Pregnancy‐Associated Stroke and Its Outcomes Among Women With Hypertensive Disorders of Pregnancy.
Menopausal Hormone Therapy- A Comprehensive Review (2020)
Purpose of Review For decades the medical community recommended menopausal hormone therapy (MHT) for prevention of atherosclerotic cardiovascular disease (ASCVD) and osteoporosis in addition to relieving unpleasant vasomotor and genitourinary sympto... Read More about Menopausal Hormone Therapy- A Comprehensive Review.
Suspected Fetal Anomalies (2020)
As part of the national screening programme, fetal anomaly screening is offered as part of the routine antenatal care in the NHS. The identification of suspected fetal anomalies causes stress and anxiety in the expectant parents. Therefore, a thoroug... Read More about Suspected Fetal Anomalies.
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