Chemical Synthesis of S-linked Glycosaminoglycans (2025)
Thesis
O’Shea, C. (2025). Chemical Synthesis of S-linked Glycosaminoglycans. (Thesis). Keele University. https://keele-repository.worktribe.com/output/1280018

Heparan sulfate (HS), a sulfated linear carbohydrate that decorates the cell surface and extracellular matrix, is ubiquitously distributed throughout the animal kingdom and represents a key regulator of biological processes. An example of a glycosami... Read More about Chemical Synthesis of S-linked Glycosaminoglycans.

Chemical synthesis of glycosaminoglycan mimetics for targeting endoglycosidase activity (2025)
Thesis
Wootton, H. S. (2025). Chemical synthesis of glycosaminoglycan mimetics for targeting endoglycosidase activity. (Thesis). Keele University. https://keele-repository.worktribe.com/output/1279726

Glycosaminoglycans are a family of extraordinary, long-chain polysaccharides that are highly abundant on the mammalian cell surface and in the extracellular matrix. These linear chains exist as proteoglycans which perform critical roles in many biolo... Read More about Chemical synthesis of glycosaminoglycan mimetics for targeting endoglycosidase activity.