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The aggregation of an alkyl-C60 derivative as a function of concentration, temperature and solvent type. (2017)
Journal Article
Hollamby, M., Smith, C., Britton, M., Danks, A., Schnepp, Z., Grillo, I., …Nakanishi, T. (2017). The aggregation of an alkyl-C60 derivative as a function of concentration, temperature and solvent type. Physical Chemistry Chemical Physics, 20(5), 3373-3380. https://doi.org/10.1039/C7CP06348B

Contrast-variation small-angle neutron scattering (CV-SANS), small-angle X-ray scattering (SAXS), nuclear magnetic resonance (NMR) measurements of diffusion and isothermal titration calorimetry (ITC) are used to gain insight into the aggregation of a... Read More about The aggregation of an alkyl-C60 derivative as a function of concentration, temperature and solvent type..

GPCR Modulation of Thieno[2,3-b]pyridine Anti-Proliferative Agents. (2017)
Journal Article
Reynisson. (2017). GPCR Modulation of Thieno[2,3-b]pyridine Anti-Proliferative Agents. Molecules, https://doi.org/10.3390/molecules22122254

A panel of docking scaffolds was developed for the known molecular targets of the anticancer agents, thieno[2,3-b]pyridines, in order to glean insight into their mechanism of action. The reported targets are the copper-trafficking antioxidant 1 prote... Read More about GPCR Modulation of Thieno[2,3-b]pyridine Anti-Proliferative Agents..

The role of resveratrol on skeletal muscle cell differentiation and myotube hypertrophy during glucose restriction (2017)
Journal Article
(2017). The role of resveratrol on skeletal muscle cell differentiation and myotube hypertrophy during glucose restriction. Molecular and Cellular Biochemistry, https://doi.org/10.1007/s11010-017-3236-1

Glucose restriction (GR) impairs muscle cell differentiation and evokes myotube atrophy. Resveratrol treatment in skeletal muscle cells improves inflammatory-induced reductions in skeletal muscle cell differentiation. We therefore hypothesised that r... Read More about The role of resveratrol on skeletal muscle cell differentiation and myotube hypertrophy during glucose restriction.

Solar H2 generation in water with a CuCrO2 photocathode modified with an organic dye and molecular Ni catalyst (2017)
Journal Article
Creissen, C., Warnan, J., & Reisner, E. (2017). Solar H2 generation in water with a CuCrO2 photocathode modified with an organic dye and molecular Ni catalyst. Chemical Science, 1439 - 1447. https://doi.org/10.1039/C7SC04476C

H2 generation using a Ni catalyst on dye-sensitised CuCrO2 highlights the benefits of using delafossite semiconductors for solar fuel production.

Natural attenuation of chlorinated ethenes in hyporheic zones: a review of key biogeochemical processes and in-situ transformation potential (2017)
Journal Article
(2017). Natural attenuation of chlorinated ethenes in hyporheic zones: a review of key biogeochemical processes and in-situ transformation potential. Water Research, 362-382. https://doi.org/10.1016/j.watres.2017.10.059

Chlorinated ethenes (CEs) are legacy contaminants whose chemical footprint is expected to persist in aquifers around the world for many decades to come. These organohalides have been reported in river systems with concerning prevalence and are though... Read More about Natural attenuation of chlorinated ethenes in hyporheic zones: a review of key biogeochemical processes and in-situ transformation potential.

The Use of Liquid Chromatography Quadrupole Time-of-Flight Mass Spectrometry and Metabonomic Profiling to Differentiate Between Normally Slaughtered and Dead On Arrival Poultry Meat (2017)
Journal Article
Thompson. (2017). The Use of Liquid Chromatography Quadrupole Time-of-Flight Mass Spectrometry and Metabonomic Profiling to Differentiate Between Normally Slaughtered and Dead On Arrival Poultry Meat. Analytical Chemistry, 12131-12136. https://doi.org/10.1021/acs.analchem.7b02749

Metabonomic profiling techniques, with established quality control methods, have been used to detect subtle metabolic differences in tissue that could aid in the discovery of fraud within the food industry. Liquid chromatography quadrupole time-of-fl... Read More about The Use of Liquid Chromatography Quadrupole Time-of-Flight Mass Spectrometry and Metabonomic Profiling to Differentiate Between Normally Slaughtered and Dead On Arrival Poultry Meat.

A Quantitative Analysis of Factors Influencing Ease of Formation and s-Bonding Strength of Oxa- and Thia-N-Heterocyclic Carbenes (2017)
Journal Article
(2017). A Quantitative Analysis of Factors Influencing Ease of Formation and s-Bonding Strength of Oxa- and Thia-N-Heterocyclic Carbenes. Journal of Organic Chemistry, https://doi.org/10.1021/acs.joc.7b02283

The index described previously (carbene relative energy of formation) has been extended to oxygen and sulfur heterocycles. This provides a quantitative overview of factors determining ease of formation of (i) neutral N-heterocyclic carbenes (NHCs) by... Read More about A Quantitative Analysis of Factors Influencing Ease of Formation and s-Bonding Strength of Oxa- and Thia-N-Heterocyclic Carbenes.

A Quantitative Analysis of Factors Influencing Ease of Formation and s-Bonding Strength of Oxa- and Thia-N-Heterocyclic Carbenes (2017)
Journal Article
(2017). A Quantitative Analysis of Factors Influencing Ease of Formation and s-Bonding Strength of Oxa- and Thia-N-Heterocyclic Carbenes. Journal of Organic Chemistry, 12485 -12491. https://doi.org/10.1021/acs.joc.7b02283

The index described previously (carbene relative energy of formation) has been extended to oxygen and sulfur heterocycles. This provides a quantitative overview of factors determining ease of formation of (i) neutral N-heterocyclic carbenes (NHCs) by... Read More about A Quantitative Analysis of Factors Influencing Ease of Formation and s-Bonding Strength of Oxa- and Thia-N-Heterocyclic Carbenes.

Development of NMR and thermal shift assays for the evaluation of Mycobacterium tuberculosis isocitrate lyase inhibitors. (2017)
Journal Article
Reynisson. (2017). Development of NMR and thermal shift assays for the evaluation of Mycobacterium tuberculosis isocitrate lyase inhibitors. MedChemComm, 2155 - 2163. https://doi.org/10.1039/c7md00456g

The enzymes isocitrate lyase (ICL) isoforms 1 and 2 are essential for Mycobacterium tuberculosis survival within macrophages during latent tuberculosis (TB). As such, ICLs are attractive therapeutic targets for the treatment of tuberculosis. However,... Read More about Development of NMR and thermal shift assays for the evaluation of Mycobacterium tuberculosis isocitrate lyase inhibitors..

Real-time tracking of metal nucleation via local perturbation of hydration layers. (2017)
Journal Article
(2017). Real-time tracking of metal nucleation via local perturbation of hydration layers. Nature communications, 971 - ?. https://doi.org/10.1038/s41467-017-01087-1

The real-time visualization of stochastic nucleation events at electrode surfaces is one of the most complex challenges in electrochemical phase formation. The early stages of metal deposition on foreign substrates are characterized by a highly dynam... Read More about Real-time tracking of metal nucleation via local perturbation of hydration layers..

Adult fly age estimations using cuticular hydrocarbons and Artificial Neural Networks in forensically important Calliphoridae species (2017)
Journal Article
Moore, H. E., Butcher, J. B., Day, C. R., & Drijfhout, F. P. (2017). Adult fly age estimations using cuticular hydrocarbons and Artificial Neural Networks in forensically important Calliphoridae species. Forensic Science International, 280, Article 233-244. https://doi.org/10.1016/j.forsciint.2017.10.001

Blowflies (Diptera: Calliphoridae) are forensically important as they are known to be one of the first to colonise human remains. The larval stage is typically used to assist a forensic entomologists with adult flies rarely used as they are difficult... Read More about Adult fly age estimations using cuticular hydrocarbons and Artificial Neural Networks in forensically important Calliphoridae species.

An automated colorimetric inline titration of CO2 concentrations in solvent flow streams using a Teflon AF-2400 tube-in-tube device (2017)
Journal Article
O'Brien, M. (2017). An automated colorimetric inline titration of CO2 concentrations in solvent flow streams using a Teflon AF-2400 tube-in-tube device. Journal of Co2 Utilization, 21, 580 - 588. https://doi.org/10.1016/j.jcou.2017.08.020

Abstract Using a number of open source software components (Python, SciPy, OpenCV, PySerial), together with an inexpensive webcam device, an automated inline colorimetric titration methodology was developed to measure CO2 concentration levels in orga... Read More about An automated colorimetric inline titration of CO2 concentrations in solvent flow streams using a Teflon AF-2400 tube-in-tube device.

Isochondodendrine and 2-norcocsuline: additional alkaloids from Triclisia subcordata induce cytotoxicity and apoptosis in ovarian cancer cell lines (2017)
Journal Article
Ijeoma Uche, F., Abed, M. N., Abdullah, M. I., Drijfhout, F. P., McCullagh, J., Claridge, T. W., …Li, W. (2017). Isochondodendrine and 2-norcocsuline: additional alkaloids from Triclisia subcordata induce cytotoxicity and apoptosis in ovarian cancer cell lines. RSC advances, 44154 -44161. https://doi.org/10.1039/C7RA08032H

Triclisia subcordata Oliv (Menispermeaceae) is used in herbal medicine for the treatment of cancer and other diseases in Africa. This study aims to isolate minor alkaloids present in this plant and assay their cytotoxic activities. Isochondodendrine... Read More about Isochondodendrine and 2-norcocsuline: additional alkaloids from Triclisia subcordata induce cytotoxicity and apoptosis in ovarian cancer cell lines.

A sensitivity analysis of the effect of pumping parameters on hydraulic fracture networks and local stresses during Shale Gas operations (2017)
Journal Article
(2017). A sensitivity analysis of the effect of pumping parameters on hydraulic fracture networks and local stresses during Shale Gas operations. Fuel, https://doi.org/10.1016/j.fuel.2017.05.004

The shale gas industry has significant impact on economies around the world, however, it is not without risk. One of the primary concerns is felt seismicity and recent earthquakes, caused by fault reactivation related to hydraulic fracturing operatio... Read More about A sensitivity analysis of the effect of pumping parameters on hydraulic fracture networks and local stresses during Shale Gas operations.

Locally Excited State - Charge Transfer State Coupled Dyes as Optically Responsive Neuron Firing Probes (2017)
Journal Article
(2017). Locally Excited State - Charge Transfer State Coupled Dyes as Optically Responsive Neuron Firing Probes. Chemistry - A European Journal, 14639-14649. https://doi.org/10.1002/chem.201703366

A selection of NIR-optically responsive neuron probes was produced comprising of a donor julolidyl group connected to a BODIPY core and several different styryl and vinylpyridinyl derived acceptor moieties. The strength of the donor–acceptor interact... Read More about Locally Excited State - Charge Transfer State Coupled Dyes as Optically Responsive Neuron Firing Probes.

Characterization and structural determination of a new anti-MET function-blocking antibody with binding epitope distinct from the ligand binding domain. (2017)
Journal Article
DiCara, D. M., Chirgadze, D. Y., Pope, A. R., Karatt-Vellatt, A., Winter, A., Slavny, P., …McCafferty, J. (2017). Characterization and structural determination of a new anti-MET function-blocking antibody with binding epitope distinct from the ligand binding domain. Scientific reports, 9000 - ?. https://doi.org/10.1038/s41598-017-09460-2

The growth and motility factor Hepatocyte Growth Factor/Scatter Factor (HGF/SF) and its receptor, the product of the MET proto-oncogene, promote invasion and metastasis of tumor cells and have been considered potential targets for cancer therapy. We... Read More about Characterization and structural determination of a new anti-MET function-blocking antibody with binding epitope distinct from the ligand binding domain..

A simple route to complex materials: the synthesis of alkaline earth–transition metal sulfides (2017)
Journal Article
Al-Shakban, M., Matthews, P., & O'Brien, P. (2017). A simple route to complex materials: the synthesis of alkaline earth–transition metal sulfides. Chemical Communications, 10058-10061. https://doi.org/10.1039/C7CC05643E

A simple, low-temperature synthesis of a family of alkaline earth metal chalcogenide thin films is reported. These materials have previously only been produced from demanding, high temperature, high pressure reactions. The decomposition of calcium, b... Read More about A simple route to complex materials: the synthesis of alkaline earth–transition metal sulfides.

Transalkylation of Toluene with 1,2,4-Trimethylbenzene over Large Pore Zeolites (2017)
Journal Article
Chansai, S., Garforth, A., Zholobenko, V., Almulla, F., & Hill, P. (2017). Transalkylation of Toluene with 1,2,4-Trimethylbenzene over Large Pore Zeolites. Industrial & Engineering Chemistry Research, 9799 -9808. https://doi.org/10.1021/acs.iecr.7b01388

Using industrially relevant operating parameters, the transalkylation of 1,2,4-trimethylbenzene (TMB) with toluene was studied. The effect of acidity and structure, increased reaction pressure, and very low levels of Pt impregnation have been investi... Read More about Transalkylation of Toluene with 1,2,4-Trimethylbenzene over Large Pore Zeolites.