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Plasmepsins IX and X are essential and druggable mediators of malaria parasite egress and invasion (2017)
Journal Article
Russo. (2017). Plasmepsins IX and X are essential and druggable mediators of malaria parasite egress and invasion. Science, 518 - 522. https://doi.org/10.1126/science.aan1478

Proteases of the malaria parasite Plasmodium falciparum have long been investigated as drug targets. The P. falciparum genome encodes 10 aspartic proteases called plasmepsins, which are involved in diverse cellular processes. Most have been studied e... Read More about Plasmepsins IX and X are essential and druggable mediators of malaria parasite egress and invasion.

Identification of heparin modifications and polysaccharide inhibitors of Plasmodium falciparum merozoite invasion that have potential for novel drug development. (2017)
Journal Article
Boyle, M. J., Skidmore, M., Dickerman, B., Cooper, L., Devlin, A., Yates, E., …Beeson, J. G. (2017). Identification of heparin modifications and polysaccharide inhibitors of Plasmodium falciparum merozoite invasion that have potential for novel drug development. Antimicrobial Agents and Chemotherapy, 61(11), https://doi.org/10.1128/AAC.00709-17

Despite recent successful control efforts, malaria remains a leading global health burden. Alarmingly, resistance to current antimalarials is increasing, and the development of new drug families is needed to maintain malaria control. Current antimala... Read More about Identification of heparin modifications and polysaccharide inhibitors of Plasmodium falciparum merozoite invasion that have potential for novel drug development..

Oral Secretions Affect HIPVs Induced by Generalist (Mythimna loreyi) and Specialist (Parnara guttata) Herbivores in Rice (2017)
Journal Article
(2017). Oral Secretions Affect HIPVs Induced by Generalist (Mythimna loreyi) and Specialist (Parnara guttata) Herbivores in Rice. Journal of Chemical Ecology, 929 - 943. https://doi.org/10.1007/s10886-017-0882-4

Plants synthesize variable mixtures of herbivore-induced plant volatiles (HIPVs) as part of their evolutionary conserved defense. To elucidate the impact of chewing herbivores with different level of adaptation on HIPV profiles in rice, we measured H... Read More about Oral Secretions Affect HIPVs Induced by Generalist (Mythimna loreyi) and Specialist (Parnara guttata) Herbivores in Rice.

Toxoplasma gondii and Neospora caninum induce different host cell responses at proteome-wide phosphorylation events; a step forward for uncovering the biological differences between these closely related parasites (2017)
Journal Article
Wastling. (2017). Toxoplasma gondii and Neospora caninum induce different host cell responses at proteome-wide phosphorylation events; a step forward for uncovering the biological differences between these closely related parasites. Parasitology Research, 2707 -2719. https://doi.org/10.1007/s00436-017-5579-7

Toxoplasma gondii and Neospora caninum are closely related intracellular protozoan parasites and tissue cyst-forming Coccidia of the phylum Apicomplexa. There are remarkable similarities between the morphology, genomes and transcriptomes of both para... Read More about Toxoplasma gondii and Neospora caninum induce different host cell responses at proteome-wide phosphorylation events; a step forward for uncovering the biological differences between these closely related parasites.

Males and females of Juniperus communis L. and Taxus baccata L. show different seasonal patterns of nitrogen and carbon content in needles (2017)
Journal Article
(2017). Males and females of Juniperus communis L. and Taxus baccata L. show different seasonal patterns of nitrogen and carbon content in needles. Acta physiologiae plantarum / Polish Academy of Sciences, Committee of Plant Physiology Genetics and Breeding, https://doi.org/10.1007/s11738-017-2489-3

Genders of dioecious species often show secondary sexual dimorphisms (not directly related to the sex organs), which may be related to reproductive demand for resources during the year. Our working hypothesis stated that phenology influences yearly s... Read More about Males and females of Juniperus communis L. and Taxus baccata L. show different seasonal patterns of nitrogen and carbon content in needles.

G-quadruplexes: prediction, characterization, and biological application (2017)
Journal Article
(2017). G-quadruplexes: prediction, characterization, and biological application. Trends in Biotechnology, 997-1013. https://doi.org/10.1016/j.tibtech.2017.06.012

Guanine (G)-rich sequences in nucleic acids can assemble into G-quadruplex structures that involve G-quartets linked by loop nucleotides. The structural and topological diversity of G-quadruplexes have attracted great attention for decades. Recent me... Read More about G-quadruplexes: prediction, characterization, and biological application.

Arcuate Nucleus Homeostatic Systems Reflect Blood Leptin Concentration but not Feeding Behaviour during Scheduled Feeding on a High Fat Diet in Mice (2017)
Journal Article
Bake, T., Baron, J., Duncan, J. S., Morgan, D. G. A., & Mercer, J. G. (2017). Arcuate Nucleus Homeostatic Systems Reflect Blood Leptin Concentration but not Feeding Behaviour during Scheduled Feeding on a High Fat Diet in Mice. Journal of Neuroendocrinology, 29(8), Article ARTN e12498. https://doi.org/10.1111/jne.12498

Hypothalamic homeostatic and forebrain reward-related genes were examined in the context of scheduled meal feeding without caloric restriction in C57BL/6 mice. Mice fed ad libitum but allowed access to a palatable high-fat (HF) diet for 2 hours a day... Read More about Arcuate Nucleus Homeostatic Systems Reflect Blood Leptin Concentration but not Feeding Behaviour during Scheduled Feeding on a High Fat Diet in Mice.

Single-molecule Analysis Reveals that DNA Replication Dynamics Vary Across the Course of Schizogony in the Malaria Parasite Plasmodium falciparum (2017)
Journal Article
(2017). Single-molecule Analysis Reveals that DNA Replication Dynamics Vary Across the Course of Schizogony in the Malaria Parasite Plasmodium falciparum. Scientific reports, https://doi.org/10.1038/s41598-017-04407-z

The mechanics of DNA replication and cell cycling are well-characterized in model organisms, but less is known about these basic aspects of cell biology in early-diverging Apicomplexan parasites, which do not divide by canonical binary fission but un... Read More about Single-molecule Analysis Reveals that DNA Replication Dynamics Vary Across the Course of Schizogony in the Malaria Parasite Plasmodium falciparum.

Evaluation of synthetic oviposition stimulants to enhance egg collection of the oriental fruit fly, Bactrocera dorsalis (Diptera: Tephritidae) (2017)
Journal Article
Kempraj, V., Aurade, R., Kamala Jayanthi, P., & Bruce, T. (2017). Evaluation of synthetic oviposition stimulants to enhance egg collection of the oriental fruit fly, Bactrocera dorsalis (Diptera: Tephritidae). Journal of Pest Science, 781 -786. https://doi.org/10.1007/s10340-017-0845-0

Tephritid flies are pests of horticultural importance throughout the globe. The oriental fruit fly, Bactrocera dorsalis (Hendel), is particularly feared because it attacks many commercial fruits and vegetables causing huge economic losses. The steril... Read More about Evaluation of synthetic oviposition stimulants to enhance egg collection of the oriental fruit fly, Bactrocera dorsalis (Diptera: Tephritidae).

Development of high-throughput methods to screen disease caused by Rhizoctonia solani AG 2-1 in oilseed rape (2017)
Journal Article
Bruce, T., Ray, R., Drizou, F., & Graham, N. (2017). Development of high-throughput methods to screen disease caused by Rhizoctonia solani AG 2-1 in oilseed rape. Plant Methods, 45 -?. https://doi.org/10.1186/s13007-017-0195-1

BACKGROUND: Rhizoctonia solani (Kühn) is a soil-borne, necrotrophic fungus causing damping off, root rot and stem canker in many cultivated plants worldwide. Oilseed rape (OSR, Brassica napus) is the primary host for anastomosis group (AG) 2-1 of R.... Read More about Development of high-throughput methods to screen disease caused by Rhizoctonia solani AG 2-1 in oilseed rape.

New applications of heparin and other glycosaminoglycans (2017)
Journal Article
Andrade De Lima, M., Rudd, T., & Yates, E. (2017). New applications of heparin and other glycosaminoglycans. Molecules, 22, 749--749. https://doi.org/10.3390/molecules22050749

Heparin, the widely used pharmaceutical anticoagulant, has been in clinical use for well over half a century. Its introduction reduced clotting risks substantially and subsequent developments, including the introduction of low-molecular-weight hepari... Read More about New applications of heparin and other glycosaminoglycans.

The aggregation pheromones of thrips (Thysanoptera) and their potential for pest management (2017)
Journal Article
(2017). The aggregation pheromones of thrips (Thysanoptera) and their potential for pest management. International Journal of Tropical Insect Science, 41-49. https://doi.org/10.1017/s1742758416000205

Aggregation pheromones have been identified and tested in the field for Frankliniella occidentalis and Thrips palmi. These pheromones are produced by adult males and attract both males and females. They are likely to be widespread across the Thripida... Read More about The aggregation pheromones of thrips (Thysanoptera) and their potential for pest management.

Targeting male mosquito swarms to control malaria vector density (2017)
Journal Article
(2017). Targeting male mosquito swarms to control malaria vector density. PloS one, e0173273 -?. https://doi.org/10.1371/journal.pone.0173273

Malaria control programs are being jeopardized by the spread of insecticide resistance in mosquito vector populations. It has been estimated that the spread of resistance could lead to an additional 120000 deaths per year, and interfere with the pros... Read More about Targeting male mosquito swarms to control malaria vector density.

Factors affecting the prey preferences of jackals (Canidae) (2017)
Journal Article
(2017). Factors affecting the prey preferences of jackals (Canidae). Mammalian Biology, 70 - 82. https://doi.org/10.1016/j.mambio.2017.02.005

Prey selection by carnivores can be affected by top-down and bottom-up factors. For example, large carnivores may facilitate food resources for mesocarnivores by providing carcasses to scavenge, however mesocarnivores may hunt large prey themselves,... Read More about Factors affecting the prey preferences of jackals (Canidae).

cis-Jasmone Elicits Aphid-Induced Stress Signalling in Potatoes (2017)
Journal Article
(2017). cis-Jasmone Elicits Aphid-Induced Stress Signalling in Potatoes. Journal of Chemical Ecology, 39 -52. https://doi.org/10.1007/s10886-016-0805-9

Elicitation of plant defense signaling that results in altered emission of volatile organic compounds (VOCs) offers opportunities for protecting plants against arthropod pests. In this study, we treated potato, Solanum tuberosum L., with the plant de... Read More about cis-Jasmone Elicits Aphid-Induced Stress Signalling in Potatoes.