Critical Mutation Rate has an Exponential Dependence on Population Size for Eukaryotic-length Genomes with Crossover (2017)
Journal Article
Channon. (2017). Critical Mutation Rate has an Exponential Dependence on Population Size for Eukaryotic-length Genomes with Crossover. Scientific reports, https://doi.org/10.1038/s41598-017-14628-x

The critical mutation rate (CMR) determines the shift between survival-of-the-fittest and survival of individuals with greater mutational robustness (“flattest”). We identify an inverse relationship between CMR and sequence length in an in silico sys... Read More about Critical Mutation Rate has an Exponential Dependence on Population Size for Eukaryotic-length Genomes with Crossover.

The creation and selection of mutations resistant to a gene drive over multiple generations in the malaria mosquito (2017)
Journal Article
M. Hammond, A., Kyrou, K., Bruttini, M., North, A., Galizi, R., Karlsson, X., …Nolan, T. (2017). The creation and selection of mutations resistant to a gene drive over multiple generations in the malaria mosquito. PLoS Genetics, e1007039 - ?. https://doi.org/10.1371/journal.pgen.1007039

Gene drives have enormous potential for the control of insect populations of medical and agricultural relevance. By preferentially biasing their own inheritance, gene drives can rapidly introduce genetic traits even if these confer a negative fitness... Read More about The creation and selection of mutations resistant to a gene drive over multiple generations in the malaria mosquito.