A sensitive and rapid assay for homologous recombination in mosquito cells: impact of vector topology and implications for gene targeting (2001)
Journal Article
(2001). A sensitive and rapid assay for homologous recombination in mosquito cells: impact of vector topology and implications for gene targeting. BMC Genetics, 21 -?. https://doi.org/10.1186/1471-2156-2-21

BACKGROUND: Recent progress in insect transgenesis has been dramatic but existing transposon-based approaches are constrained by position effects and potential instability. Gene targeting would bring a number of benefits, however progress requires a... Read More about A sensitive and rapid assay for homologous recombination in mosquito cells: impact of vector topology and implications for gene targeting.

Gene targeting in mosquito cells: a demonstration of 'knockout' technology in extrachromosomal gene arrays (2001)
Journal Article
(2001). Gene targeting in mosquito cells: a demonstration of 'knockout' technology in extrachromosomal gene arrays. BMC Genetics, 11-?. https://doi.org/10.1186/1471-2156-2-11

BACKGROUND: Gene targeting would offer a number of advantages over current transposon-based strategies for insect transformation. These include freedom from both position effects associated with quasi-random integration and concerns over transgene in... Read More about Gene targeting in mosquito cells: a demonstration of 'knockout' technology in extrachromosomal gene arrays.

Genetics of premenstrual syndrome: investigation of specific serotonin receptor polymorphisms
Thesis
Genetics of premenstrual syndrome: investigation of specific serotonin receptor polymorphisms. https://keele-repository.worktribe.com/output/405115

Premenstrual dysphoric disorder (PMDD) is a distressing and disabling syndrome causing a significant degree of impairment on daily functioning and interpersonal relationships in 3-8% of the women. With the convincing evidence that PMS is inheritable... Read More about Genetics of premenstrual syndrome: investigation of specific serotonin receptor polymorphisms.

Critical mutation rates in small populations
Thesis
Critical mutation rates in small populations. https://keele-repository.worktribe.com/output/405309

Mutation introduces change at the sequence level. There is a critical mutation rate above which changes occur too frequently for natural selection to maintain the population's genetic makeup. This thesis examines the relationship between this critica... Read More about Critical mutation rates in small populations.

The genetics and ecology of male reproductive investments in the malaria mosquito Anopheles gambiae s.s
Thesis
The genetics and ecology of male reproductive investments in the malaria mosquito Anopheles gambiae s.s. https://keele-repository.worktribe.com/output/407923

Malaria continues to be a major global health problem due to high mortality and morbidity rate in endemic regions. An. gambiae s.s is the major vector in endemic African countries. About 198 million cases of malaria were recorded globally in 2013 and... Read More about The genetics and ecology of male reproductive investments in the malaria mosquito Anopheles gambiae s.s.