Risk of incident vascular disease in patients with gout: an observational study in the Clinical Practice Research Datalink
Thesis
Clarson, L. E. Risk of incident vascular disease in patients with gout: an observational study in the Clinical Practice Research Datalink. https://keele-repository.worktribe.com/output/407012

Gout is the most prevalent inflammatory arthritis, predominantly managed in primary care. Both hyperuricaemia (the biochemical precursor to gout) and other inflammatory arthritides, e.g. rheumatoid arthritis, have been shown to increase risk of vascu... Read More about Risk of incident vascular disease in patients with gout: an observational study in the Clinical Practice Research Datalink.

Structural studies of a2-macroglobulin from the horseshoe crab Limulus polyphemus
Thesis
Nicosia, M. Structural studies of a2-macroglobulin from the horseshoe crab Limulus polyphemus. https://keele-repository.worktribe.com/output/407399

This work is focused on structural studies of the innate immune protein a2-macroglobulin from the horseshoe crab, Limulus Polyphemus, using crystallography and structure prediction software to reveal clues about the structure and function of this key... Read More about Structural studies of a2-macroglobulin from the horseshoe crab Limulus polyphemus.

Engineering neural cells in implantable materials
Thesis
Engineering neural cells in implantable materials. https://keele-repository.worktribe.com/output/409060

A key goal in regenerative therapy is to improve outcomes following the devastating consequences of spinal cord injury. Yearly, between 250,000 to 500,000 people suffer permanent injury to the spinal cord. The cost to the individual, their families a... Read More about Engineering neural cells in implantable materials.

Enhancing the complexity of neural tissue engineering platforms for repair of neurological injury
Thesis
Enhancing the complexity of neural tissue engineering platforms for repair of neurological injury. https://keele-repository.worktribe.com/output/405102

The extent of regeneration is often limited after spinal cord injury (SCI), due to the post-injury microenvironment that is unsupportive of nerve fibre regeneration and the limited intrinsic reparative capacity of neurons. Current mainstream clinical... Read More about Enhancing the complexity of neural tissue engineering platforms for repair of neurological injury.