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A review of prednisolone prescribing for children with acute asthma in the UK (2016)
Journal Article
Gilchrist, F. J., Ahmad, A. N., Batchelor, H. K., Marriott, J. F., & Lenney, W. (2016). A review of prednisolone prescribing for children with acute asthma in the UK. Journal of Asthma, 53(6), 563 -566. https://doi.org/10.3109/02770903.2015.1118498

INTRODUCTION: Worldwide asthma guidelines recommend short courses of oral prednisolone in children with acute exacerbations generating high prescription numbers. There is a paucity of evidence to inform the optimal dose and course duration. This has... Read More about A review of prednisolone prescribing for children with acute asthma in the UK.

Diabetic retinopathy in patients who do not meet the diagnostic criteria for cystic fibrosis related diabetes (2015)
Journal Article
Gilchrist, F. (2015). Diabetic retinopathy in patients who do not meet the diagnostic criteria for cystic fibrosis related diabetes. Practical Diabetes, 333-335a. https://doi.org/10.1002/pdi.1984

The UK Cystic Fibrosis (CF) Trust guidelines state that the diagnosis of CF related diabetes (CFRD) should only be made after an oral glucose tolerance test in the diabetic range and hyperglycaemia on serial monitoring. We report three patients with... Read More about Diabetic retinopathy in patients who do not meet the diagnostic criteria for cystic fibrosis related diabetes.

Research is the Future, the Future is……. (2015)
Journal Article
Gilchrist, F. J. (2015). Research is the Future, the Future is……. Paediatric Respiratory Reviews, 17, 32 - 33. https://doi.org/10.1016/j.prrv.2015.08.008

Over the past two decades, Professor Lenney has established the Paediatric Respiratory Department at the Royal Stoke University Hospital as a centre recognised for high quality research. A broad portfolio of clinical and laboratory based research is... Read More about Research is the Future, the Future is……..

Developing a handheld record for patients with cystic fibrosis (2015)
Journal Article
Narayan, O., Davies, S., Tibbins, C., Rees, J., Lenney, W., & Gilchrist, F. (2015). Developing a handheld record for patients with cystic fibrosis. Patient Related Outcome Measures, 2015(6), 225 - 228. https://doi.org/10.2147/PROM.S86298

Patient handheld records (PHHRs) promote self-management and empower the holder to take a more active role in the management of their disease. They have been used successfully in improving preventative care for children and have contributed to improv... Read More about Developing a handheld record for patients with cystic fibrosis.

Bacterial distribution in the lungs of children with protracted bacterial bronchitis (2014)
Journal Article
Narang, R., Bakewell, K., Peach, J., Clayton, S., Samuels, M., Alexander, J., Lenney, W., & Gilchrist, F. J. (2014). Bacterial distribution in the lungs of children with protracted bacterial bronchitis. PloS one, 9(9), Article e108523. https://doi.org/10.1371/journal.pone.0108523

OBJECTIVES: Flexible bronchoscopy with bronchoalveolar lavage (FB-BAL) is increasingly used for the microbiological confirmation of protracted bacterial bronchitis (PBB) in children with a chronic wet cough. At our centre, when performing FB-BAL for... Read More about Bacterial distribution in the lungs of children with protracted bacterial bronchitis.

The potential of closed circuit lung clearance index (LCI) to provide longitudinal clinical utility in cystic fibrosis (CF)
Presentation / Conference
Gilchrist. The potential of closed circuit lung clearance index (LCI) to provide longitudinal clinical utility in cystic fibrosis (CF). Presented at https://erj.ersjournals.com/content/54/suppl_63/PA332

Background: Closed circuit washin offers a quicker test with the advantages of an exogenous tracer to measure FRC and LCI. We measured LCI in CF paediatric and adult outpatient clinics to assess repeatability of LCI and track changes over time, and i... Read More about The potential of closed circuit lung clearance index (LCI) to provide longitudinal clinical utility in cystic fibrosis (CF).

Rapid and portable MBW measurements for clinical application of LCI in routine clinics
Presentation / Conference
Gilchrist. Rapid and portable MBW measurements for clinical application of LCI in routine clinics. Presented at ERS Lung Science Conference 2016

Background: Assessment of lung clearance index (LCI) is typically a prolonged process (>20mins), performed in physiology labs. This has hindered routine clinical application and restricted repeat assessments to annual reviews. We have developed a por... Read More about Rapid and portable MBW measurements for clinical application of LCI in routine clinics.

REPRODUCIBILITY OF LUNG CLEARANCE INDEX (LCI) IN CLINICALLY STABLE ADULTS WITH MILD CYSTIC FIBROSIS (CF)
Presentation / Conference
Gilchrist. REPRODUCIBILITY OF LUNG CLEARANCE INDEX (LCI) IN CLINICALLY STABLE ADULTS WITH MILD CYSTIC FIBROSIS (CF). Presented at British Thoracic Society Winter Meeting 2016

Background In order for lung clearance index (LCI) to be a clinically useful measurement, a better understanding is required of short-term variability. LCI-SEARCH is a longitudinal study in children and adults with CF, with LCI measured at each clini... Read More about REPRODUCIBILITY OF LUNG CLEARANCE INDEX (LCI) IN CLINICALLY STABLE ADULTS WITH MILD CYSTIC FIBROSIS (CF).

Female sex is associated with increased risk of early readmission with asthma in Staffordshire children
Presentation / Conference
Gilchrist. Female sex is associated with increased risk of early readmission with asthma in Staffordshire children. Presented at ERS International Congress 2017

Background: Asthma is the commonest medical reason for a child to be admitted to hospital in the UK. c.15% are readmitted within 3 months.

Aim: We undertook a retrospective case-control study to determine the predictors of readmission.

Methods:... Read More about Female sex is associated with increased risk of early readmission with asthma in Staffordshire children.

The British Lung Foundation asthma management programme improving children's asthma control
Presentation / Conference
Gilchrist. The British Lung Foundation asthma management programme improving children's asthma control. Presented at ERS International Congress 2017

Background: The 10-year Finland asthma programme showed that educating healthcare workers, patients and families reduces hospital admissions and asthma-related deaths (1).

Aim: The Department of Health and the Scottish Government funded a 2-year p... Read More about The British Lung Foundation asthma management programme improving children's asthma control.

Incidence of post-procedure complications in children undergoing elective flexible bronchoscopy
Presentation / Conference
Gilchrist. Incidence of post-procedure complications in children undergoing elective flexible bronchoscopy. Presented at ERS International Congress 2019

Background: Paediatric flexible bronchoscopy with bronchoalveolar lavage (FB-BAL) is a safe procedure with a low incidence of intra-procedure complications. There is a paucity of data on the incidence of post-procedure complications.

Aim: To inves... Read More about Incidence of post-procedure complications in children undergoing elective flexible bronchoscopy.