Therapeutic Effects of Hypoxic and Pro-Inflammatory Priming of Mesenchymal Stem Cell-Derived Extracellular Vesicles in Inflammatory Arthritis (2021)
Journal Article
Kay, A. G., Roach, P., Morgan, R., Lodge, R., Hyland, M., Piccinini, A. M., Forsyth, N. R., Kehoe, O., & Treadwell, K. (2021). Therapeutic Effects of Hypoxic and Pro-Inflammatory Priming of Mesenchymal Stem Cell-Derived Extracellular Vesicles in Inflammatory Arthritis. International Journal of Molecular Sciences, 23(1), 126 - 126. https://doi.org/10.3390/ijms23010126

<jats:p>Mesenchymal stem cells (MSCs) immunomodulate inflammatory responses through paracrine signalling, including via secretion of extracellular vesicles (EVs) in the cell secretome. We evaluated the therapeutic potential of MSCs-derived small EVs... Read More about Therapeutic Effects of Hypoxic and Pro-Inflammatory Priming of Mesenchymal Stem Cell-Derived Extracellular Vesicles in Inflammatory Arthritis.

Decision making in percutaneous coronary intervention in patients with cancer: balancing ischaemic and bleeding risk. (2021)
Journal Article
Mamas. (2021). Decision making in percutaneous coronary intervention in patients with cancer: balancing ischaemic and bleeding risk. https://doi.org/10.1093/eurheartj/ehab403

Risk for Myocardial Infarction Following 5-Fluorouracil Treatment in Patients With Gastrointestinal Cancer: A Nationwide Registry-Based Study. (2021)
Journal Article
Mamas. (2021). Risk for Myocardial Infarction Following 5-Fluorouracil Treatment in Patients With Gastrointestinal Cancer: A Nationwide Registry-Based Study. https://doi.org/10.1016/j.jaccao.2021.11.001

Background: Myocardial infarction is a cardiac adverse event associated with 5-fluorouracil (5-FU). There are limited data on the incidence, risk, and prognosis of 5-FU-associated myocardial infarction. Objectives: The aim of this study was to examin... Read More about Risk for Myocardial Infarction Following 5-Fluorouracil Treatment in Patients With Gastrointestinal Cancer: A Nationwide Registry-Based Study..

Effects of an Online Education Program on Physical Therapists' Confidence in Weight Management for People With Osteoarthritis: A Randomized Controlled Trial (2021)
Journal Article
Allison, K., Jones, S., Hinman, R. S., Briggs, A. M., Sumithran, P., Quicke, J., Holden, M., Chiavaroli, N., Crofts, S., George, E., Foster, N., & Bennell, K. (2021). Effects of an Online Education Program on Physical Therapists' Confidence in Weight Management for People With Osteoarthritis: A Randomized Controlled Trial. Arthritis Care and Research, 75(4), 835-847. https://doi.org/10.1002/acr.24828

OBJECTIVE: Evaluate effects of an online education program about weight management for osteoarthritis on physiotherapists' self-reported confidence in knowledge and skills in weight management, and attitudes toward obesity.

METHOD: A two-group ran... Read More about Effects of an Online Education Program on Physical Therapists' Confidence in Weight Management for People With Osteoarthritis: A Randomized Controlled Trial.

Co-designing an Adaption of a Mobile App to Enhance Communication, Safety, and Well-being Among People Living at Home With Early-Stage Dementia: Protocol for an Exploratory Multiple Case Study (2021)
Journal Article
(2021). Co-designing an Adaption of a Mobile App to Enhance Communication, Safety, and Well-being Among People Living at Home With Early-Stage Dementia: Protocol for an Exploratory Multiple Case Study. JMIR Research Protocols, e19543 - e19543

<jats:sec> <jats:title>Background</jats:title> <jats:p>There is a growing interest in using mobile apps to support communication, safety, and well-being. Evidence directly from people with dementia regarding the usability, usefulness, and relevance o... Read More about Co-designing an Adaption of a Mobile App to Enhance Communication, Safety, and Well-being Among People Living at Home With Early-Stage Dementia: Protocol for an Exploratory Multiple Case Study.

Suicide and other causes of death among working-age and older adults in the year after discharge from in-patient mental healthcare in England: matched cohort study (2021)
Journal Article
Musgrove, R., Carr, M., Chew-Graham, C., Mughal, F., Kapur, N., Ashcroft, D., & Webb, R. (2021). Suicide and other causes of death among working-age and older adults in the year after discharge from in-patient mental healthcare in England: matched cohort study. British Journal of Psychiatry, 1 - 8. https://doi.org/10.1192/bjp.2021.176

<jats:sec id="S0007125021001768_sec_a1"> <jats:title>Background</jats:title> <jats:p>Evidence for risk of dying by suicide and other causes following discharge from in-patient psychiatric care throughout adulthood is sparse.</jats:p> </jats:sec> <jat... Read More about Suicide and other causes of death among working-age and older adults in the year after discharge from in-patient mental healthcare in England: matched cohort study.

Addressing disparities of care in non-ST-segment elevation myocardial infarction (NSTEMI) patients without standard modifiable risk factors: insights from a nationwide cohort study (2021)
Journal Article
Rashid, Mamas, & Nolan. (2021). Addressing disparities of care in non-ST-segment elevation myocardial infarction (NSTEMI) patients without standard modifiable risk factors: insights from a nationwide cohort study. European Journal of Preventive Cardiology, 1084-1092. https://doi.org/10.1093/eurjpc/zwab200

Background: The importance of standard modifiable cardiovascular risk factors (SMuRFs) in preventing non-ST segment myocardial infarction (NSTEMI) is established. However, NSTEMI may present in the absence of SMuRFs, and little is known about their o... Read More about Addressing disparities of care in non-ST-segment elevation myocardial infarction (NSTEMI) patients without standard modifiable risk factors: insights from a nationwide cohort study.

Misdiagnosis of aortic dissection: A systematic review of the literature (2021)
Journal Article
Mallen. (2021). Misdiagnosis of aortic dissection: A systematic review of the literature. American Journal of Emergency Medicine, https://doi.org/10.1016/j.ajem.2021.11.047

Background
Aortic dissection is a rare but potentially catastrophic condition. Misdiagnosis of aortic dissection is not uncommon as symptoms can overlap with other diagnoses.

Objective
We conducted a systematic review to better understand the fa... Read More about Misdiagnosis of aortic dissection: A systematic review of the literature.

Radiographic validation of a self-report instrument for hallux valgus (2021)
Journal Article
Gupta, V., Lingham, A., Marshall, M., Rathod‐Mistry, T., Menz, H. B., & Roddy, E. (2022). Radiographic validation of a self-report instrument for hallux valgus. Musculoskeletal Care, 20(2), 383-389. https://doi.org/10.1002/msc.1604

Background Hallux valgus (HV) is a common condition causing substantial morbidity. Radiographic assessment is the gold standard for grading severity but is not always feasible in clinical/research settings. HV line-drawings, consisting of five drawin... Read More about Radiographic validation of a self-report instrument for hallux valgus.

How do people with knee osteoarthritis perceive and manage flares? A qualitative study (2021)
Journal Article
Parry, E., Dikomitis, L., Peat, G., & Chew-Graham, C. (2022). How do people with knee osteoarthritis perceive and manage flares? A qualitative study. British Journal of General Practice Open (BJGP Open), 6(2), BJGPO.2021.0086 - BJGPO.2021.0086. https://doi.org/10.3399/BJGPO.2021.0086

Background Acute flares in people with osteoarthritis (OA) are poorly understood. There is uncertainty around the nature of flares, their impact, and how these are managed.

Aim To explore understandings and experiences of flares in people with kne... Read More about How do people with knee osteoarthritis perceive and manage flares? A qualitative study.

Mobilizing physiotherapy knowledge: Understanding the best evidence and barriers to implementation of hydrotherapy for musculoskeletal disease. (2021)
Journal Article
Dziedzic. (2021). Mobilizing physiotherapy knowledge: Understanding the best evidence and barriers to implementation of hydrotherapy for musculoskeletal disease. Physiotherapy Theory and Practice, 1 - 8. https://doi.org/10.1080/09593985.2021.2010847

OBJECTIVES: To explore two linked strategies to highlight the best current available evidence for hydrotherapy and to explore the barriers and enablers to mobilizing this evidence into practice. METHOD: Phase 1: The best published evidence for hydrot... Read More about Mobilizing physiotherapy knowledge: Understanding the best evidence and barriers to implementation of hydrotherapy for musculoskeletal disease..

External validation of a model to predict women most at risk of postpartum venous thromboembolism: Maternity clot risk. (2021)
Journal Article
Ban, L., Abdul Sultan, A., West, J., Tata, L. J., Riley, R. D., Nelson-Piercy, C., & Grainge, M. J. (2021). External validation of a model to predict women most at risk of postpartum venous thromboembolism: Maternity clot risk. Thrombosis Research, 202-210. https://doi.org/10.1016/j.thromres.2021.05.020

INTRODUCTION: Venous thromboembolism (VTE) is the leading cause of direct maternal mortality in high-income countries. We previously developed a risk prediction score for postpartum venous thromboembolism (VTE) in women without a previous VTE. In thi... Read More about External validation of a model to predict women most at risk of postpartum venous thromboembolism: Maternity clot risk..

Developing an easy read, public version of moving forward–NIHR research themed review physiotherapy for musculoskeletal health and wellbeing (2021)
Presentation / Conference Contribution
Campbell, L., Hallam, F., Evans, N., Swaithes, L., Duffy, H., Dziedzic, K., & Stevenson, K. Developing an easy read, public version of moving forward–NIHR research themed review physiotherapy for musculoskeletal health and wellbeing. Presented at Virtual Physiotherapy UK

Trends of Sex Differences in Clinical Outcomes After Myocardial Infarction in the United States. (2021)
Journal Article
Rashid, & Mamas. (2021). Trends of Sex Differences in Clinical Outcomes After Myocardial Infarction in the United States. https://doi.org/10.1016/j.cjco.2021.06.012

Background: Female patients have been shown to experience worse clinical outcomes after acute myocardial infarction (AMI) compared with male patients. However, it is unclear what trend these differences followed over time. Methods: Data from patients... Read More about Trends of Sex Differences in Clinical Outcomes After Myocardial Infarction in the United States..

Core outcome measurement instrument selection for physical function in hand osteoarthritis using the OMERACT Filter 2.1 process. (2021)
Journal Article
Dziedzic. (2021). Core outcome measurement instrument selection for physical function in hand osteoarthritis using the OMERACT Filter 2.1 process. Seminars in Arthritis and Rheumatism, 1311 - 1319. https://doi.org/10.1016/j.semarthrit.2021.08.014

Objective: Physical function is one of the Outcome Measures in Rheumatology (OMERACT) core outcome domains for hand osteoarthritis studies. Our aim was to select appropriate instrument(s) to measure this domain, as part of the development of a core o... Read More about Core outcome measurement instrument selection for physical function in hand osteoarthritis using the OMERACT Filter 2.1 process..

Implementation of the JIGSAW-E model for osteoarthritis. A role for Extended Scope Practitioners in primary care (2021)
Journal Article
Frost, H., Cowie, J., Tooman, T., Quicke, J., Evans, N., Cottrell, E., & Dziedzic, K. (2021). Implementation of the JIGSAW-E model for osteoarthritis. A role for Extended Scope Practitioners in primary care. Physiotherapy, 113(S1), e31 - e32. https://doi.org/10.1016/j.physio.2021.10.261

Working across boundaries to develop innovations to support the mental health needs of patients with persistent neck and back pain (2021)
Presentation / Conference Contribution
Stevenson, K., Kingstone, T., Evans, N., Campbell, L., Duffy, H., Lambley-Burke, R., & Dziedzic, K. Working across boundaries to develop innovations to support the mental health needs of patients with persistent neck and back pain. Presented at Physiotherapy UK 2020, Virtual

THE METOCLOPRAMIDE FOR AVOIDING PNEUMONIA AFTER STROKE (MAPS-2) TRIAL: A SINGLE-BLIND RCT OF METOCLOPRAMIDE FOR THE PREVENTION OF PNEUMONIA IN PATIENTS WITH DYSPHAGIA AFTER STROKE (2021)
Presentation / Conference Contribution
Roffe, C., Bath, P., Warusevitane, A., Smith, C., Dixit, A., Sprigg, N., Helliwell, B., Phillips, N., Sim, J., Jowett, S., & Ogollah, R. (2021, November). THE METOCLOPRAMIDE FOR AVOIDING PNEUMONIA AFTER STROKE (MAPS-2) TRIAL: A SINGLE-BLIND RCT OF METOCLOPRAMIDE FOR THE PREVENTION OF PNEUMONIA IN PATIENTS WITH DYSPHAGIA AFTER STROKE. Presented at UK Stroke Forum 2021, Virtual

Why are children with asthma bullied? A risk factor analysis. (2021)
Journal Article
Gilchrist. (2021). Why are children with asthma bullied? A risk factor analysis. Archives of Disease in Childhood, https://doi.org/10.1136/archdischild-2021-321641

The links between bullying and asthma have not been explored in children. We wanted to determine the child/parent factors and attitudes associated with asthma-related bullying. Individual child/parent responses of children with asthma (N=943) from th... Read More about Why are children with asthma bullied? A risk factor analysis..

Predictors of interest in predictive testing for rheumatoid arthritis among first degree relatives of rheumatoid arthritis patients (2021)
Journal Article
Mallen, Wells, I., T Zemedikun, D., Simons, G., J Stack, R., D Mallen, C., Raza, K., & Falahee, M. (2022). Predictors of interest in predictive testing for rheumatoid arthritis among first degree relatives of rheumatoid arthritis patients. Rheumatology, 61(8), https://doi.org/10.1093/rheumatology/keab890

OBJECTIVES: There is increasing interest in prediction and prevention of rheumatoid arthritis (RA). It is important to understand the views of those at risk to inform the development of effective approaches. First-degree relatives (FDRs) of RA patien... Read More about Predictors of interest in predictive testing for rheumatoid arthritis among first degree relatives of rheumatoid arthritis patients.