Underrecording of osteoarthritis in United Kingdom primary care electronic health record data (2018)
Journal Article
Yu, D., Jordan, K., & Peat, G. (2018). Underrecording of osteoarthritis in United Kingdom primary care electronic health record data. Clinical Epidemiology, 1195-1201. https://doi.org/10.2147/CLEP.S160059

Purpose: Primary care electronic health records are increasingly used to estimate the occurrence of osteoarthritis (OA). We aimed to estimate the extent and trend over time of underrecording of severe OA patients in UK primary care electronic health... Read More about Underrecording of osteoarthritis in United Kingdom primary care electronic health record data.

Mortality after admission for heart failure in the UK compared with Japan. (2018)
Journal Article
(2018). Mortality after admission for heart failure in the UK compared with Japan. Open Heart, e000811 - ?. https://doi.org/10.1136/openhrt-2018-000811

Objective: Mortality amongst patients hospitalised for heart failure (HHF) in Western and Asian countries may differ, but this has not been investigated using individual patient-level data (IPLD). We sought to remedy this through rigorous statistical... Read More about Mortality after admission for heart failure in the UK compared with Japan..

Early vs Standard Discharge After Transcatheter Aortic Valve Implantation: A Systematic Review and Meta-analysis (2018)
Journal Article
Mamas. (2018). Early vs Standard Discharge After Transcatheter Aortic Valve Implantation: A Systematic Review and Meta-analysis. JACC. Cardiovascular interventions, 1759-1771. https://doi.org/10.1016/j.jcin.2018.04.042

Objectives: We sought to assess the clinical outcomes of patients undergoing transcatheter aortic valve implantation (TAVI) with early discharge (ED) versus standard discharge (SD) pathways.

Background: Minimalist approaches for TAVI have been dev... Read More about Early vs Standard Discharge After Transcatheter Aortic Valve Implantation: A Systematic Review and Meta-analysis.

Coexistence of plantar calcaneal spurs and plantar fascial thickening in individuals with plantar heel pain (2018)
Journal Article
Menz, H. B., Thomas, M., Marshall, M., Rathod-Mistry, T., Hall, A., Chesterton, L. S., Peat, G. M., & Roddy, E. (2019). Coexistence of plantar calcaneal spurs and plantar fascial thickening in individuals with plantar heel pain. Rheumatology, 58(2), 237-245. https://doi.org/10.1093/rheumatology/key266

Objectives
To examine associations between plantar calcaneal spurs, plantar fascia thickening and plantar heel pain (PHP), and to determine whether tenderness on palpation of the heel differentiates between these presentations.

Methods
Adults... Read More about Coexistence of plantar calcaneal spurs and plantar fascial thickening in individuals with plantar heel pain.

Persistent sex disparities in clinical outcomes with percutaneous coronary intervention: Insights from 6.6 million PCI precedures in the United States (2018)
Journal Article
Ensor, J., Burke, D., Kwok, C., Riley, R., Holmvang, L., Mamas, M., Sirker, A., Potts, J., Martinez, S., Gulati, M., Alasnag, M., & Rashid, M. (2018). Persistent sex disparities in clinical outcomes with percutaneous coronary intervention: Insights from 6.6 million PCI precedures in the United States. PloS one, https://doi.org/10.1371/journal.pone.0203325

Background
Prior studies have reported inconsistencies in the baseline risk profile, comorbidity burden and their association with clinical outcomes in women compared to men. More importantly, there is limited data around the sex differences and how... Read More about Persistent sex disparities in clinical outcomes with percutaneous coronary intervention: Insights from 6.6 million PCI precedures in the United States.

Single Incision Lateral Release for Hallux Valgus Using A Cervical Biopsy Blade: A Cadaveric Study (2018)
Journal Article
Kennedy, J., Berg, A., Welsh, L., & Mehta, J. (2018). Single Incision Lateral Release for Hallux Valgus Using A Cervical Biopsy Blade: A Cadaveric Study. Foot, 35-38. https://doi.org/10.1016/j.foot.2018.04.005

Abstract The role of lateral release is widely accepted and regarded as a key step in management of hallux valgus. There remains however debate in literature in regards to which structures should be divided and the method of approach. We therefore de... Read More about Single Incision Lateral Release for Hallux Valgus Using A Cervical Biopsy Blade: A Cadaveric Study.

Cartilage cavity-an MRI marker of cartilage lesions in knee OA with Data from CCBR, OAI, and PROOF (2018)
Journal Article
(2018). Cartilage cavity-an MRI marker of cartilage lesions in knee OA with Data from CCBR, OAI, and PROOF. Magnetic Resonance in Medicine, 1219 -1232. https://doi.org/10.1002/mrm.27130

Purpose
We introduce the quantitative, continuous marker cartilage cavity that quantifies cartilage lesions by the total lesion volume. The aim was to quantify small lesions as well as large, full-depth lesions.

Methods
We included 315 knees fro... Read More about Cartilage cavity-an MRI marker of cartilage lesions in knee OA with Data from CCBR, OAI, and PROOF.

The associated features of multiple somatic symptom complexes (2018)
Journal Article
Chew-Graham. (2018). The associated features of multiple somatic symptom complexes. Journal of Psychosomatic Research, 1-8. https://doi.org/10.1016/j.jpsychores.2018.06.007

Abstract Objective To assess whether two or more functional somatic symptom complexes (SSCs) showed stronger association with psychosocial correlates than single or no SSC after adjustment for depression/anxiety and general medical disorders. Methods... Read More about The associated features of multiple somatic symptom complexes.

Total / high-density lipoprotein cholesterol and cardiovascular disease (re)hospitalisation nadir in type 2 diabetes (2018)
Journal Article
Yu. (2018). Total / high-density lipoprotein cholesterol and cardiovascular disease (re)hospitalisation nadir in type 2 diabetes. Journal of Lipid Research, 1745-1750. https://doi.org/10.1194/jlr.P084269

Total cholesterol to high density lipoprotein cholesterol ratio (TC/HDL) is an important prognostic factor for cardiovascular disease (CVD). This study used restricted cubic spline modelling to investigate the dose-response associations between TC/HD... Read More about Total / high-density lipoprotein cholesterol and cardiovascular disease (re)hospitalisation nadir in type 2 diabetes.

Hypertriglyceridemic-waist is more predictive of abnormal liver and renal function in an Australian population than a Chinese population (2018)
Journal Article
Yu. (2018). Hypertriglyceridemic-waist is more predictive of abnormal liver and renal function in an Australian population than a Chinese population. Obesity Research and Clinical Practice, 438-444. https://doi.org/10.1016/j.orcp.2018.07.010

OBJECTIVE
We aimed to compare the association of hypertriglyceridemic-waist (HTGW), with glycaemia, liver and renal function between a Chinese and an Australian population using 3 HTGW definitions.

METHODS
1454 Australian and 5824 Chinese adults... Read More about Hypertriglyceridemic-waist is more predictive of abnormal liver and renal function in an Australian population than a Chinese population.

Multiple Sclerosis-Secondary Progressive Multi-Arm Randomisation Trial (MS-SMART): a multiarm phase IIb randomised, double-blind, placebo-controlled clinical trial comparing the efficacy of three neuroprotective drugs in secondary progressive multiple sclerosis (2018)
Journal Article
(2018). Multiple Sclerosis-Secondary Progressive Multi-Arm Randomisation Trial (MS-SMART): a multiarm phase IIb randomised, double-blind, placebo-controlled clinical trial comparing the efficacy of three neuroprotective drugs in secondary progressive multiple sclerosis. BMJ Open, https://doi.org/10.1136/bmjopen-2018-021944

Introduction
The major unmet need in multiple sclerosis (MS) is for neuroprotective therapies that can slow (or ideally stop) the rate of disease progression. The UK MS Society Clinical Trials Network (CTN) was initiated in 2007 with the purpose of... Read More about Multiple Sclerosis-Secondary Progressive Multi-Arm Randomisation Trial (MS-SMART): a multiarm phase IIb randomised, double-blind, placebo-controlled clinical trial comparing the efficacy of three neuroprotective drugs in secondary progressive multiple sclerosis.

Impulse control disorder in Parkinson's disease: a meta-analysis of cognitive, affective and motivational correlates (2018)
Journal Article
Martini, A., Dal Lago, D., Edelstyn, N. M., Grange, J. A., & Tamburin, S. (2018). Impulse control disorder in Parkinson's disease: a meta-analysis of cognitive, affective and motivational correlates. Frontiers in Neurology, https://doi.org/10.3389/fneur.2018.00654

Background In Parkinson’s disease (PD), impulse control disorders (ICDs) develop as side-effect of dopaminergic replacement therapy (DRT). One hypothesis is that DRT overdoses less-severely affected dopamine-modulated circuits on which cognition, aff... Read More about Impulse control disorder in Parkinson's disease: a meta-analysis of cognitive, affective and motivational correlates.

Association of osteoarthritis risk factors with knee and hip pain in a population-based sample of 29-59 year olds in Denmark: a cross-sectional analysis. (2018)
Journal Article
(2018). Association of osteoarthritis risk factors with knee and hip pain in a population-based sample of 29-59 year olds in Denmark: a cross-sectional analysis. BMC Musculoskeletal Disorders, 300. https://doi.org/10.1186/s12891-018-2183-7

BACKGROUND: This study aimed to a) describe the prevalence of knee and hip osteoarthritis risk factors in a population of 29-59 year old individuals, b) estimate the association between persistent knee/hip pain and osteoarthritis risk factors, and c)... Read More about Association of osteoarthritis risk factors with knee and hip pain in a population-based sample of 29-59 year olds in Denmark: a cross-sectional analysis..

Diagnostic accuracy of diagnostic imaging for lumbar disc herniation in adults with low back pain or sciatica is unknown; a systematic review (2018)
Journal Article
Kim, J.-H., van Rijn, R. M., van Tulder, M. W., Koes, B. W., de Boer, M. R., Ginai, A. Z., Ostelo, R. W., van der Windt, D. A., & Verhagen, A. P. (2018). Diagnostic accuracy of diagnostic imaging for lumbar disc herniation in adults with low back pain or sciatica is unknown; a systematic review. Chiropractic & Manual Therapies, 25, Article 37. https://doi.org/10.1186/s12998-018-0207-x

Main text: We aim to summarize the available evidence on the diagnostic accuracy of imaging (index test) compared to surgery (reference test) for identifying lumbar disc herniation (LDH) in adult patients. For this systematic review we searched MEDLI... Read More about Diagnostic accuracy of diagnostic imaging for lumbar disc herniation in adults with low back pain or sciatica is unknown; a systematic review.

Towards prevention of post-traumatic osteoarthritis: report from an international expert working group on considerations for the design and conduct of interventional studies following acute knee injury (2018)
Journal Article
Watt, F., Corp, N., Kingsbury, S., Frobell, R., Englund, M., Felson, D., Levesque, M., Majumdar, S., Wilson, C., Beard, D., Lohmander, L., Kraus, V., Roemer, F., Conaghan, P., Mason, D., Adams, J., Blank, M., Batt, M., Biggs, P., Busse-Morris, M., …Bierma-Zeinstra, S. (2019). Towards prevention of post-traumatic osteoarthritis: report from an international expert working group on considerations for the design and conduct of interventional studies following acute knee injury. Osteoarthritis and Cartilage, 27(1), 23-33. https://doi.org/10.1016/j.joca.2018.08.001

Objective
There are few guidelines for clinical trials of interventions for prevention of post-traumatic osteoarthritis (PTOA), reflecting challenges in this area. An international multi-disciplinary expert group including patients was convened to g... Read More about Towards prevention of post-traumatic osteoarthritis: report from an international expert working group on considerations for the design and conduct of interventional studies following acute knee injury.

Uptake of the NICE osteoarthritis guidelines in primary care: a survey of older adults with joint pain (2018)
Journal Article
Healey, E. L., Afolabi, E. K., Lewis, M., Edwards, J. J., Jordan, K. P., Finney, A., Jinks, C., Hay, E. M., & Dziedzic, K. S. (2018). Uptake of the NICE osteoarthritis guidelines in primary care: a survey of older adults with joint pain. BMC Musculoskeletal Disorders, 19, Article 295. https://doi.org/10.1186/s12891-018-2196-2

Background
Osteoarthritis (OA) is a leading cause of pain and disability. NICE OA guidelines (2008) recommend that patients with OA should be offered core treatments in primary care. Assessments of OA management have identified a need to improve pri... Read More about Uptake of the NICE osteoarthritis guidelines in primary care: a survey of older adults with joint pain.

Quality and acceptability of patient-reported outcome measures used to assess fatigue in axial spondyloarthritis (axSpA): a systematic review (protocol) (2018)
Journal Article
(2018). Quality and acceptability of patient-reported outcome measures used to assess fatigue in axial spondyloarthritis (axSpA): a systematic review (protocol). Systematic Reviews, 116 -?. https://doi.org/10.1186/s13643-018-0777-7

BACKGROUND: The prevalence of axial spondyloarthritis (axSpA) is estimated between 0.15 and 1.2%, with many of those patients experiencing severe fatigue. Current axSpA assessment guidance recommends use of a single-item visual analogue scale for fat... Read More about Quality and acceptability of patient-reported outcome measures used to assess fatigue in axial spondyloarthritis (axSpA): a systematic review (protocol).

Self-reported sleep duration and quality and cardiovascular disease and mortality: a dose-response meta-analysis (2018)
Journal Article
Chew-Graham, & Mamas. (2018). Self-reported sleep duration and quality and cardiovascular disease and mortality: a dose-response meta-analysis. Journal of the American Heart Association Cardiovascular and Cerebrovascular Disease, https://doi.org/10.1161/jaha.118.008552

Abstract Background: There is growing evidence that sleep duration and quality may be associated with cardiovascular harm and mortality. Methods and Results: We conducted a systematic review, meta-analysis and spline analysis of prospective cohort st... Read More about Self-reported sleep duration and quality and cardiovascular disease and mortality: a dose-response meta-analysis.

Characterisation of tissue-type metabolic content in secondary progressive multiple sclerosis: a magnetic resonance spectroscopic imaging study. (2018)
Journal Article
(2018). Characterisation of tissue-type metabolic content in secondary progressive multiple sclerosis: a magnetic resonance spectroscopic imaging study. Journal of Neurology, 265, 1795 - 1802. https://doi.org/10.1007/s00415-018-8903-y

Proton magnetic resonance spectroscopy yields metabolic information and has proved to be a useful addition to structural imaging in neurological diseases. We applied short-echo time Spectroscopic Imaging in a cohort of 42 patients with secondary prog... Read More about Characterisation of tissue-type metabolic content in secondary progressive multiple sclerosis: a magnetic resonance spectroscopic imaging study..

Long-term clinical and cost-effectiveness of collaborative care (versus usual care) for people with mental–physical multimorbidity: cluster-randomised trial (2018)
Journal Article
Chew-Graham, C. (2018). Long-term clinical and cost-effectiveness of collaborative care (versus usual care) for people with mental–physical multimorbidity: cluster-randomised trial. British Journal of Psychiatry, 456-463. https://doi.org/10.1192/bjp.2018.70

Background
Collaborative care can support the treatment of depression in people with long-term conditions, but long-term benefits and costs are unknown.

Aims
To explore the long-term (24-month) effectiveness and cost-effectiveness of collaborati... Read More about Long-term clinical and cost-effectiveness of collaborative care (versus usual care) for people with mental–physical multimorbidity: cluster-randomised trial.