Cost-effectiveness of WHO Problem Management Plus for adults with mood and anxiety disorders in a post-conflict area of Pakistan: randomised controlled trial. (2020)
Journal Article
Farooq. (2020). Cost-effectiveness of WHO Problem Management Plus for adults with mood and anxiety disorders in a post-conflict area of Pakistan: randomised controlled trial. British Journal of Psychiatry, 623-629. https://doi.org/10.1192/bjp.2020.138

BACKGROUND: With the development of evidence-based interventions for treatment of priority mental health conditions in humanitarian settings, it is important to establish the cost-effectiveness of such interventions to enable their scale-up. AIMS: To... Read More about Cost-effectiveness of WHO Problem Management Plus for adults with mood and anxiety disorders in a post-conflict area of Pakistan: randomised controlled trial..

Supervised treatment in outpatients for schizophrenia plus (STOPS+): protocol for a cluster randomised trial of a community-based intervention to improve treatment adherence and reduce the treatment gap for schizophrenia in Pakistan (2020)
Journal Article
Shepherd, T. A., Ul-Haq, Z., Ul-Haq, M., Firaz Khan, M., Afridi, A., Dikomitis, L., Robinson, M. E., Lewis, M., Rahman, A., Dziedzic, K., Saeed, U., Riaz Awan, N., Mallen, C., & Farooq, S. (2020). Supervised treatment in outpatients for schizophrenia plus (STOPS+): protocol for a cluster randomised trial of a community-based intervention to improve treatment adherence and reduce the treatment gap for schizophrenia in Pakistan. BMJ Open, 10(6), https://doi.org/10.1136/bmjopen-2019-034709

Introduction: There is a significant treatment gap, with only a few community-based services for people with schizophrenia in Low- and Middle-Income countries. Poor treatment adherence in schizophrenia is associated with poorer health outcomes, suici... Read More about Supervised treatment in outpatients for schizophrenia plus (STOPS+): protocol for a cluster randomised trial of a community-based intervention to improve treatment adherence and reduce the treatment gap for schizophrenia in Pakistan.

The neuroprotective role of polyunsaturated fatty acids in a palmitic acid model of diabetes mellitus type 2 (2020)
Thesis
Benn, E. E. The neuroprotective role of polyunsaturated fatty acids in a palmitic acid model of diabetes mellitus type 2. (Thesis). Keele University. https://keele-repository.worktribe.com/output/417199

The negative ways in which diabetes affects the brain, and the role of neural insulin and glucose is an interesting research topic as research has shown a correlation between neurodegenerative diseases and diabetes. This thesis focuses on how polyuns... Read More about The neuroprotective role of polyunsaturated fatty acids in a palmitic acid model of diabetes mellitus type 2.

Does the heterogeneity of autism undermine the neurodiversity paradigm? (2020)
Journal Article
Hughes. (2020). Does the heterogeneity of autism undermine the neurodiversity paradigm?. Bioethics, https://doi.org/10.1111/bioe.12780

The neurodiversity paradigm is presented by its proponents as providing a philosophical foundation for the activism of the neurodiversity movement. Its central claims are that autism and other neurodivergent conditions are not disorders because they... Read More about Does the heterogeneity of autism undermine the neurodiversity paradigm?.

Label-Free Nanoimaging of Neuromelanin in the Brain by Soft X-ray Spectromicroscopy. (2020)
Journal Article
Telling, & Everett. (2020). Label-Free Nanoimaging of Neuromelanin in the Brain by Soft X-ray Spectromicroscopy. Angewandte Chemie International Edition, https://doi.org/10.1002/anie.202000239

A hallmark of Parkinson's disease is the death of neuromelanin-pigmented neurons, but the role of neuromelanin is unclear. The in situ characterization of neuromelanin remains dependent on detectable pigmentation, rather than direct quantification of... Read More about Label-Free Nanoimaging of Neuromelanin in the Brain by Soft X-ray Spectromicroscopy..

Through fog: An autoethnography of childhood emotional neglect. (2019)
Thesis
Blanchard, A. Through fog: An autoethnography of childhood emotional neglect. (Thesis). Keele University. https://keele-repository.worktribe.com/output/413773

Childhood emotional neglect is increasingly recognised as significant and widespread, potentially linked to adult depression and anxiety, yet it remains hidden, poorly understood, ill-defined, foggy. Less widely researched than other forms of child m... Read More about Through fog: An autoethnography of childhood emotional neglect..

Magnetic assistive and hydrogel technology for enhanced survival and function of neurons (2018)
Thesis
Al-Shakli, A. F. Magnetic assistive and hydrogel technology for enhanced survival and function of neurons. (Thesis). Keele University. https://keele-repository.worktribe.com/output/411469

Neurons are the targets of injury and disease in many neurological conditions, and achieving neuronal survival/repair is a key goal for regenerative medicine. In this context, genetic engineering of neurons offers a platform for (i) basic research to... Read More about Magnetic assistive and hydrogel technology for enhanced survival and function of neurons.

Delivering nanoengineered neural stem cells within neurosurgical grade biomaterials (2018)
Thesis
Finch, L. Delivering nanoengineered neural stem cells within neurosurgical grade biomaterials. (Thesis). Keele University. https://keele-repository.worktribe.com/output/418125

Achieving neural regeneration after spinal cord injury (SCI) represents a significant challenge. Neural stem cell (NSC) therapy offers replacement of damaged cells and delivery of pro-regenerative factors, but >95% of cells die when transplanted to s... Read More about Delivering nanoengineered neural stem cells within neurosurgical grade biomaterials.

Vitamin B3 and Neurodevelopment in Parkinson's Disease (2018)
Presentation / Conference
(2018, October). Vitamin B3 and Neurodevelopment in Parkinson's Disease. Presented at 2018 International Congress, Hong Kong

Vitamin B3 and Neurodevelopment in Parkinson’s Disease
A. Williams, S. Griffin, R. Fricker (Birmingham, United Kingdom)

Meeting: 2018 International Congress

ABSTRACT NUMBER: 592

Keywords: Cell replacement therapy, Dopaminergic neurons

Se... Read More about Vitamin B3 and Neurodevelopment in Parkinson's Disease.

Unusual neuropathological features and increased brain aluminium in a resident of Camelford, UK. (2017)
Journal Article
(2017). Unusual neuropathological features and increased brain aluminium in a resident of Camelford, UK. Neuropathology and Applied Neurobiology, 537-541. https://doi.org/10.1111/nan.12417

The possible role of aluminium in the pathogenesis of Alzheimer's disease (AD) has been hotly debated over the past few decades. Although the so-called ‘aluminium hypothesis’ was popular in the 1970s and 1980s, it has gradually fallen out of favour i... Read More about Unusual neuropathological features and increased brain aluminium in a resident of Camelford, UK..

Health promotion and screening for people with an intellectual disability (2017)
Journal Article
(2017). Health promotion and screening for people with an intellectual disability. InnovAiT, 157 - 164. https://doi.org/10.1177/1755738016682982

<jats:p> People with intellectual disability have significantly worse health than those without, and have a higher level of complex health needs. The life expectancy for men and women is 13 and 20 years shorter, respectively, than the general populat... Read More about Health promotion and screening for people with an intellectual disability.

Analysis of the dynamics of temporal relationships of neural activities using optical imaging data (2016)
Journal Article
(2016). Analysis of the dynamics of temporal relationships of neural activities using optical imaging data. Journal of Computational Neuroscience, 107 - 121. https://doi.org/10.1007/s10827-016-0630-8

The temporal relationship between the activities of neurons in biological neural systems is critically important for the correct delivery of the functionality of these systems. Fine measurement of temporal relationships of neural activities using mic... Read More about Analysis of the dynamics of temporal relationships of neural activities using optical imaging data.

Deploying clinical grade magnetic nanoparticles with magnetic fields to magnetolabel neural stem cells in adherent versus suspension cultures (2015)
Journal Article
Weinberg, D., Adams, C., & Chari, D. (2015). Deploying clinical grade magnetic nanoparticles with magnetic fields to magnetolabel neural stem cells in adherent versus suspension cultures. RSC advances, 5, 43353-43360. https://doi.org/10.1039/c5ra07481a

Neural stem cells (NSCs) have a high therapeutic potential for patients with neurological disease/injury given their neuroregenerative and immunomodulatory capabilities. In recent years, magnetic nanoparticles (MNPs) have been used as contrast agents... Read More about Deploying clinical grade magnetic nanoparticles with magnetic fields to magnetolabel neural stem cells in adherent versus suspension cultures.

Robust uptake of magnetic nanoparticles (MNPs) by central nervous system (CNS) microglia: implications for particle uptake in mixed neural cell populations (2010)
Journal Article
(2010). Robust uptake of magnetic nanoparticles (MNPs) by central nervous system (CNS) microglia: implications for particle uptake in mixed neural cell populations. International Journal of Molecular Sciences, 967 - 981. https://doi.org/10.3390/ijms11030967

Magnetic nanoparticles (MNPs) are important contrast agents used to monitor a range of neuropathological processes; microglial cells significantly contribute to MNP uptake in sites of pathology. Microglial activation occurs following most CNS patholo... Read More about Robust uptake of magnetic nanoparticles (MNPs) by central nervous system (CNS) microglia: implications for particle uptake in mixed neural cell populations.

Variable and constant errors of perceived angle size
Thesis
Hakiel, S. Variable and constant errors of perceived angle size. https://keele-repository.worktribe.com/output/413663

Experiments were carried out to characterise the perception of angles in terms of the acuity and constant error of comparisons of acute angle sizes. Both measures, determined by the forced choice method of constant stimululi, were found to increase l... Read More about Variable and constant errors of perceived angle size.

Neuronal organization within the mammalian dorsal lateral geniculate complex and adjacent pulvinar nuclei: a comparative approach
Thesis
Mason, R. Neuronal organization within the mammalian dorsal lateral geniculate complex and adjacent pulvinar nuclei: a comparative approach. https://keele-repository.worktribe.com/output/413541

This dissertation attempts to understand the organization of some of the nuclei which constitute the mammalian visual thalamus through an electrophysiological and histological investigation of the cat and rat aided by an evaluation of comparative neu... Read More about Neuronal organization within the mammalian dorsal lateral geniculate complex and adjacent pulvinar nuclei: a comparative approach.

Adaptive cancellation techniques for noise reduction in electrocardiography
Thesis
Mukalaf, A. Adaptive cancellation techniques for noise reduction in electrocardiography. https://keele-repository.worktribe.com/output/416224

This thesis describes an investigation of the application of adaptive filtering techniques in electrocardiography (ECG), with particular reference to exercise testing. The main objective in this study was to observe the effectiveness of adaptive meth... Read More about Adaptive cancellation techniques for noise reduction in electrocardiography.

A psychophysical study of the dynamics of colour vision using wavelength-modulated light
Thesis
Tyler, C. W. A psychophysical study of the dynamics of colour vision using wavelength-modulated light. https://keele-repository.worktribe.com/output/412687

Visual comparison of patterns: the significance of pattern transformation and pattern arrangement in the visual field
Thesis
Visual comparison of patterns: the significance of pattern transformation and pattern arrangement in the visual field. https://keele-repository.worktribe.com/output/414664

The two main types of scheme for the internal representation and internal processing of visual stimuli involve either a 'pointlllistic' internal representation to which various internal compensatory transformations can be applied, or a structured, in... Read More about Visual comparison of patterns: the significance of pattern transformation and pattern arrangement in the visual field.

Temporal characteristics of spoken consonants as discriminants in automatic speech recognition
Thesis
Green, P. D. Temporal characteristics of spoken consonants as discriminants in automatic speech recognition. https://keele-repository.worktribe.com/output/412678

Three time-varying functions, which can be extracted. directly from the raw speech waveform, are of importance in the field of automatic speech recognition. These functions arc the zero-crossing rate, the turnaround (local maximum or minimum) rate an... Read More about Temporal characteristics of spoken consonants as discriminants in automatic speech recognition.