New approaches suggest term and preterm human fetal membranes may have distinct biomechanical properties. (2022)
Journal Article
Yang, & Wu. (2022). New approaches suggest term and preterm human fetal membranes may have distinct biomechanical properties. Scientific reports, 12, Article 5109. https://doi.org/10.1038/s41598-022-09005-2

Preterm prelabour rupture of membranes is the leading cause of preterm birth and its associated infant mortality and morbidity. However, its underlying mechanism remains unknown. We utilized two novel biomechanical assessment techniques, ball indenta... Read More about New approaches suggest term and preterm human fetal membranes may have distinct biomechanical properties..

Pictorial methods to assess heavy menstrual bleeding in research and clinical practice: a systematic literature review (2020)
Journal Article
(2020). Pictorial methods to assess heavy menstrual bleeding in research and clinical practice: a systematic literature review. BMC Women's Health, 24 - 24. https://doi.org/10.1186/s12905-020-0887-y

Pictorial blood loss assessment charts (PBACs) represent the most widely used method to assess menstrual blood loss (MBL) in clinical trials. The aims of this review were to: (1) determine the diagnostic accuracy of PBACs that have been validated aga... Read More about Pictorial methods to assess heavy menstrual bleeding in research and clinical practice: a systematic literature review.

Chorionic and amniotic membrane-derived stem cells have distinct, and gestational diabetes mellitus independent, proliferative, differentiation, and immunomodulatory capacities (2019)
Journal Article
Wu. (2019). Chorionic and amniotic membrane-derived stem cells have distinct, and gestational diabetes mellitus independent, proliferative, differentiation, and immunomodulatory capacities. Stem Cell Research, 40, Article 101537. https://doi.org/10.1016/j.scr.2019.101537

Placental membrane-derived mesenchymal stem cells (MSCs), with the advantages of being non-invasive and having fewer ethical issues, are a promising source for cell therapy. Gestational diabetes (GDM) alters the uterine environment and may affect the... Read More about Chorionic and amniotic membrane-derived stem cells have distinct, and gestational diabetes mellitus independent, proliferative, differentiation, and immunomodulatory capacities.

Changes in advanced glycation content, structural and mechanical properties of vaginal tissue during pregnancy and in prolapse (2018)
Thesis
Weli, H. K. (2018). Changes in advanced glycation content, structural and mechanical properties of vaginal tissue during pregnancy and in prolapse. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/411339

Introduction: Pelvic organ prolapse is present in up to 50% of women. It is commoner in older women, often above 50 years of age and associated with hormonal e.g. oestrogen decline, and stiffer vaginal tissue. Pregnancy, on the contrary is a physiolo... Read More about Changes in advanced glycation content, structural and mechanical properties of vaginal tissue during pregnancy and in prolapse.

Preterm birth and maternal cardiovascular outcomes: a systematic review and meta-analysis (2018)
Journal Article
Mamas. (2018). Preterm birth and maternal cardiovascular outcomes: a systematic review and meta-analysis. Journal of the American Heart Association Cardiovascular and Cerebrovascular Disease, https://doi.org/10.1161/JAHA.117.007809

Background
Preterm delivery (<37 weeks gestational age) affects 11% of all pregnancies, but data are conflicting whether preterm birth is associated with long-term adverse maternal cardiovascular outcomes. We aimed to systematically evaluate and sum...

Identification and evaluation of anticancer compounds from three Nigerian plants used in traditional medicines (2017)
Presentation / Conference
Rosa Johnson-Ajinwo, O., Richardson, A., & Li, W. (2017, September). Identification and evaluation of anticancer compounds from three Nigerian plants used in traditional medicines. Presented at IUPHAR, Aberdeen

Ovarian cancer is the second leading cause of death among women in the gynaecological category of cancers. The current post surgery treatment which involves the use of platinum-based therapy with its attendant adverse drug-resistance often results in... Read More about Identification and evaluation of anticancer compounds from three Nigerian plants used in traditional medicines.

Advanced glycation products' levels and mechanical properties of vaginal tissue in pregnancy (2017)
Journal Article
Weli, H. K., Akhtar, R., Chang, Z., Li, W., Cooper, J., & Yang, Y. (2017). Advanced glycation products' levels and mechanical properties of vaginal tissue in pregnancy. European Journal of Obstetrics and Gynecology and Reproductive Biology, 78-85. https://doi.org/10.1016/j.ejogrb.2017.04.037

Objectives
Non-enzymatic glycation is closely associated with altered mechanical properties of connective tissue. Pregnancy, marked with high levels of female hormones, confers unique alteration to the mechanical properties of pelvic connective tiss... Read More about Advanced glycation products' levels and mechanical properties of vaginal tissue in pregnancy.

Non-contraceptive oestrogen-containing preparations for controlling symptoms of premenstrual syndrome. (2017)
Journal Article
(2017). Non-contraceptive oestrogen-containing preparations for controlling symptoms of premenstrual syndrome. Cochrane Database of Systematic Reviews, CD010503 - ?. https://doi.org/10.1002/14651858.CD010503.pub2

BACKGROUND: Premenstrual syndrome (PMS) is a psychological and somatic disorder of unknown aetiology, with symptoms typically including irritability, depression, mood swings, bloating, breast tenderness and sleep disturbances. About 3% to 10% of wome... Read More about Non-contraceptive oestrogen-containing preparations for controlling symptoms of premenstrual syndrome..

Preeclampsia and Future Cardiovascular Health (2017)
Journal Article
Wu, P., Haththotuwa, R., Shing Kwok, C., Babu, A., Kotronias, R. A., Rushton, C., …Mamas, M. A. (2017). Preeclampsia and Future Cardiovascular Health. Circulation: Cardiovascular Quality and Outcomes, 10(2), https://doi.org/10.1161/circoutcomes.116.003497

Background—
Preeclampsia is a pregnancy-specific disorder resulting in hypertension and multiorgan dysfunction. There is growing evidence that these effects persist after pregnancy. We aimed to systematically evaluate and quantify the evidence on th... Read More about Preeclampsia and Future Cardiovascular Health.

Pre-eclampsia Diagnosis and Treatment Options: A Review of Published Economic Assessments (2015)
Journal Article
(2015). Pre-eclampsia Diagnosis and Treatment Options: A Review of Published Economic Assessments. PharmacoEconomics, 1069 -1082. https://doi.org/10.1007/s40273-015-0291-x

BACKGROUND: Pre-eclampsia is a pregnancy complication affecting both mother and fetus. Although there is no proven effective method to prevent pre-eclampsia, early identification of women at risk of pre-eclampsia could enhance appropriate application... Read More about Pre-eclampsia Diagnosis and Treatment Options: A Review of Published Economic Assessments.