Discovery, synthesis and antibacterial evaluation of phenolic compounds from Cylicodiscus gabunensis (2019)
Journal Article
Aldulaimi, O., Drijfhout, F., Uche, F. I., Horrocks, P., & Li, W. (2019). Discovery, synthesis and antibacterial evaluation of phenolic compounds from Cylicodiscus gabunensis. BMC Complementary and Alternative Medicine, 183 -?. https://doi.org/10.1186/s12906-019-2589-2

BACKGROUND
Cylicodiscus gabunensis Harms (Family Leguminosae) (CG) is an African medicinal plant used as a treatment of various ailments including malaria, liver diseases, and gastrointestinal disturbances. Its extracts showed potent in vitro antiba... Read More about Discovery, synthesis and antibacterial evaluation of phenolic compounds from Cylicodiscus gabunensis.

Dietary geranylgeraniol can limit the activity of pitavastatin as a potential treatment for drug-resistant ovarian cancer (2017)
Journal Article
de Wolf, E., Abdullah, M. I., Jones, S. M., Menezes, K., Moss, D. M., Drijfhout, F., Hart, S., Hoskins, C., Stronach, E. A., & Richardson, A. (2017). Dietary geranylgeraniol can limit the activity of pitavastatin as a potential treatment for drug-resistant ovarian cancer. Scientific reports, https://doi.org/10.1038/s41598-017-05595-4

Pre-clinical and retrospective studies of patients using statins to reduce plasma cholesterol have suggested that statins may be useful to treat cancer. However, prospective clinical trials have yet to demonstrate significant efficacy. We have previo... Read More about Dietary geranylgeraniol can limit the activity of pitavastatin as a potential treatment for drug-resistant ovarian cancer.