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Age-related changes in the biophysical and morphological characteristics of mouse cochlear outer hair cells. (2020)
Journal Article
(2020). Age-related changes in the biophysical and morphological characteristics of mouse cochlear outer hair cells. Journal of Physiology, 3891 - 3910. https://doi.org/10.1113/JP279795

KEY POINTS: Age-related hearing loss (ARHL) is a very heterogeneous disease, resulting from cellular senescence, genetic predisposition and environmental factors (e.g. noise exposure). Currently, we know very little about age-related changes occurrin... Read More about Age-related changes in the biophysical and morphological characteristics of mouse cochlear outer hair cells..

Schistosoma mansoni cercarial elastase (SmCE): differences in immunogenic properties of native and recombinant forms (2017)
Journal Article
El-Faham, M., Wheatcroft-Francklow, K., Price, H., Sayers, J., & Doenhoff, M. (2017). Schistosoma mansoni cercarial elastase (SmCE): differences in immunogenic properties of native and recombinant forms. Parasitology, 144(10), 1356-1364. https://doi.org/10.1017/s0031182017000658

The Schistosoma mansoni cercarial elastase (SmCE) has previously been shown to be poorly immunogenic in mice. However, a minority of mice were able to produce antibodies against SmCE after multiple immunizations with crude preparations containing the... Read More about Schistosoma mansoni cercarial elastase (SmCE): differences in immunogenic properties of native and recombinant forms.

Altered brain gene expression but not steroid biochemistry in a genetic mouse model of neurodevelopmental disorder (2014)
Journal Article
Trent, S., Fry, J. P., Ojarikre, O. A., & Davies, W. (2014). Altered brain gene expression but not steroid biochemistry in a genetic mouse model of neurodevelopmental disorder. Molecular Autism, 5, Article 21. https://doi.org/10.1186/2040-2392-5-21

Background
The 39,XY*O mouse, which lacks the orthologues of the ADHD and autism candidate genes STS (steroid sulphatase) and ASMT (acetylserotonin O-methyltransferase), exhibits behavioural phenotypes relevant to developmental disorders. The neurob... Read More about Altered brain gene expression but not steroid biochemistry in a genetic mouse model of neurodevelopmental disorder.

Assessment of magnetic particles for neural stem cell-based therapies
Thesis
Adams, C. F. Assessment of magnetic particles for neural stem cell-based therapies. https://keele-repository.worktribe.com/output/407295

Transplantation of genetically engineered neural stem cells (NSCs) into sites of central nervous system (CNS) disease/injury is a promising strategy to promote repair of damaged tissue. However, translating this strategy into the clinic requires seve... Read More about Assessment of magnetic particles for neural stem cell-based therapies.

Genetic and behavioural mechanisms of reproductive isolation and speciation in recently-diverged sibling species of the malaria vector Anopheles gambiae s.l.
Thesis
Genetic and behavioural mechanisms of reproductive isolation and speciation in recently-diverged sibling species of the malaria vector Anopheles gambiae s.l. https://keele-repository.worktribe.com/output/408366

Anopheles gambiae s.l. species are reported as the most important vectors due to their ability to spread and exploit both temporary and man-made breeding sites. These factors combined with their capacity to transmit malaria, make them wide-open subje... Read More about Genetic and behavioural mechanisms of reproductive isolation and speciation in recently-diverged sibling species of the malaria vector Anopheles gambiae s.l..