Thermally dynamic examination of local order in nanocrystalline hydroxyapatite (2022)
Journal Article
Arnold, E. L., Gosling, S., Davies, S. K., Cross, H. L., Evans, P., Keeble, D. S., …Rogers, K. D. (2022). Thermally dynamic examination of local order in nanocrystalline hydroxyapatite. Journal of Solid State Chemistry, 315, Article 123474. https://doi.org/10.1016/j.jssc.2022.123474

The main mineral component of bone is hydroxyapatite, a commonly nanocrystalline material which presents many challenges for those trying to characterize it. Here, local structure is analyzed using X-ray total scattering for synthetic samples, to ena... Read More about Thermally dynamic examination of local order in nanocrystalline hydroxyapatite.

A multi-modal exploration of heterogeneous physico–chemical properties of DCIS breast microcalcifications (2022)
Journal Article
Gosling, S., Calabrese, D., Nallala, J., Greenwood, C., Pinder, S., King, L., …Stone, N. (2022). A multi-modal exploration of heterogeneous physico–chemical properties of DCIS breast microcalcifications. Analyst, 147(8), 1641-1654. https://doi.org/10.1039/d1an01548f

Ductal carcinoma in situ (DCIS) is frequently associated with breast calcification. This study combines multiple analytical techniques to investigate the heterogeneity of these calcifications at the micrometre scale. X-ray diffraction, scanning elect... Read More about A multi-modal exploration of heterogeneous physico–chemical properties of DCIS breast microcalcifications.

Calcification Microstructure Reflects Breast Tissue Microenvironment (2019)
Journal Article
Gosling, S., Scott, R., Greenwood, C., Bouzy, P., Nallala, J., D. Lyburn, I., …Rogers, K. (2019). Calcification Microstructure Reflects Breast Tissue Microenvironment. Journal of Mammary Gland Biology and Neoplasia, 333-342. https://doi.org/10.1007/s10911-019-09441-3

Microcalcifications are important diagnostic indicators of disease in breast tissue. Tissue microenvironments differ in many aspects between normal and cancerous cells, notably extracellular pH and glycolytic respiration. Hydroxyapatite microcalcific... Read More about Calcification Microstructure Reflects Breast Tissue Microenvironment.