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Musculoskeletal Health and Work: Development and Internal–External Cross-Validation of a Model to Predict Risk of Work Absence and Presenteeism in People Seeking Primary Healthcare (2024)
Journal Article
Archer, L., Peat, G., Snell, K. I. E., Hill, J. C., Dunn, K. M., Foster, N. E., Bishop, A., van der Windt, D., & Wynne-Jones, G. (2024). Musculoskeletal Health and Work: Development and Internal–External Cross-Validation of a Model to Predict Risk of Work Absence and Presenteeism in People Seeking Primary Healthcare. Journal of Occupational Rehabilitation, https://doi.org/10.1007/s10926-024-10223-w

Purpose
To develop and validate prediction models for the risk of future work absence and level of presenteeism, in adults seeking primary healthcare with musculoskeletal disorders (MSD).

Methods
Six studies from the West-Midlands/Northwest regi... Read More about Musculoskeletal Health and Work: Development and Internal–External Cross-Validation of a Model to Predict Risk of Work Absence and Presenteeism in People Seeking Primary Healthcare.

Symptom patterns and life with post-acute COVID-19 in children aged 8-17: a mixed methods studyprotocol. (2023)
Journal Article
Faux-Nightingale, A., Burton, C., Twohig, H., Bucknall, M., Carroll, W., Chew-Graham, C., Dunn, K., Gilchrist, F., Helliwell, T., Lawton, O., Lawton, S., Mallen, C., Saunders, B., Van Der Windt, D., & Welsh, V. (2023). Symptom patterns and life with post-acute COVID-19 in children aged 8-17: a mixed methods studyprotocol. British Journal of General Practice Open (BJGP Open), 7(2), Article BJGPO20220149. https://doi.org/10.3399/bjgpo.2022.0149

Background: While there is a substantial body of knowledge about acute COVID-19, less is known about long-COVID, where symptoms continue beyond 4 weeks.

Aim: To describe longer-term effects of COVID-19 infection in children and young people (CYP)... Read More about Symptom patterns and life with post-acute COVID-19 in children aged 8-17: a mixed methods studyprotocol..

Overall prognosis of acute and chronic musculoskeletal, widespread, and neuropathic pain in children and adolescents (2023)
Journal Article
Dunn, K., Montgomery, L. R., Andreucci, A., Kamper, S. J., van der Windt, D., Michaleff, Z. A., Swain, M., Williams, C. M., Campbell, P., Dario, A., Montgomery, L., Kamper, S., van der Windt, D. A., Michaleff, Z., Dunn, K. M., Williams, C., & Swain, M. S. (2023). Overall prognosis of acute and chronic musculoskeletal, widespread, and neuropathic pain in children and adolescents. Cochrane Database of Systematic Reviews, 2023(2), https://doi.org/10.1002/14651858.cd014773

Objectives
This is a protocol for a Cochrane Review (prognosis). The objectives are as follows:

We aim to describe the overall prognosis (focusing on the pain course) and the negative impact(s) of acute and chronic musculoskeletal, widespread, an... Read More about Overall prognosis of acute and chronic musculoskeletal, widespread, and neuropathic pain in children and adolescents.

Refinement and validation of a tool for stratifying patients with musculoskeletal pain (2021)
Journal Article
Dunn, K. M., Campbell, P., Lewis, M., Hill, J. C., van der Windt, D. A., Afolabi, E., Protheroe, J., Wathall, S., Jowett, S., Oppong, R., Mallen, C. D., Hay, E. M., & Foster, N. E. (2021). Refinement and validation of a tool for stratifying patients with musculoskeletal pain. European Journal of Pain, 25(10), 2081-2093. https://doi.org/10.1002/ejp.1821

AbstractBackgroundPatients with musculoskeletal pain in different body sites share common prognostic factors. Using prognosis to stratify and treatment match can be clinically and cost‐effective. We aimed to refine and validate the Keele STarT MSK To... Read More about Refinement and validation of a tool for stratifying patients with musculoskeletal pain.

Family-based Interventions Benefit Individuals with Musculoskeletal Pain in the Short-term but not in the Long Term: A Systematic Review and Meta-analysis. (2021)
Journal Article
Fritsch, C., Ferreira, M., da Silva, A., Simic, M., Dunn, K., Campbell, P., Foster, N., & Ferreira, P. (2021). Family-based Interventions Benefit Individuals with Musculoskeletal Pain in the Short-term but not in the Long Term: A Systematic Review and Meta-analysis. Clinical Journal of Pain, 37(2), 140-157. https://doi.org/10.1097/AJP.0000000000000897

INTRODUCTION: The benefits of family-based interventions for patients with musculoskeletal pain have been previously shown in individual randomised controlled trials (RCTs), but no systematic review has summarised their effects. MATERIALS AND METHODS... Read More about Family-based Interventions Benefit Individuals with Musculoskeletal Pain in the Short-term but not in the Long Term: A Systematic Review and Meta-analysis..

Prevalence, Characteristics and Clinical Course of Neuropathic Pain in Primary Care Patients Consulting with Low Back-related Leg Pain. (2020)
Journal Article
Dunn. (2020). Prevalence, Characteristics and Clinical Course of Neuropathic Pain in Primary Care Patients Consulting with Low Back-related Leg Pain. Clinical Journal of Pain, https://doi.org/10.1097/AJP.0000000000000879

OBJECTIVES: Little is known about the epidemiology of neuropathic pain in primary care patients consulting with low back-related leg pain. We aimed to describe prevalence, characteristics and clinical course of low back-related leg pain patients with... Read More about Prevalence, Characteristics and Clinical Course of Neuropathic Pain in Primary Care Patients Consulting with Low Back-related Leg Pain..

Stratified versus usual care for the management of primary care patients with sciatica: the SCOPiC RCT (2020)
Journal Article
Foster, N. E., Konstantinou, K., Lewis, M., Ogollah, R., Saunders, B., Kigozi, J., Jowett, S., Bartlam, B., Artus, M., Hill, J. C., Hughes, G., Mallen, C. D., Hay, E. M., van der Windt, D. A., Robinson, M., & Dunn, K. M. (2020). Stratified versus usual care for the management of primary care patients with sciatica: the SCOPiC RCT. Health Technology Assessment, 2(7), e401-e411. https://doi.org/10.3310/hta24490

BACKGROUND: Sciatica has a substantial impact on patients and society. Current care is 'stepped', comprising an initial period of simple measures of advice and analgesia, for most patients, commonly followed by physiotherapy, and then by more intensi... Read More about Stratified versus usual care for the management of primary care patients with sciatica: the SCOPiC RCT.

Stratified care versus usual care for management of patients presenting with sciatica in primary care (SCOPiC): a randomised controlled trial (2020)
Journal Article
Konstantinou, K., Lewis, M., Dunn, K., Hay, E., Van Der Windt, D., Artus, M., Hill, J., Hughes, G., Robinson, M., Saunders, B., Bartlam, B., Mallen, C., Ogollah, R., Kigozi, J., Jowett, S., & Foster, N. (2020). Stratified care versus usual care for management of patients presenting with sciatica in primary care (SCOPiC): a randomised controlled trial. The Lancet Rheumatology, 2(7), e401-e411. https://doi.org/10.1016/S2665-9913%2820%2930099-0

Background
Sciatica has a substantial impact on individuals and society. Stratified care has been shown to lead to better outcomes among patients with non-specific low back pain, but it has not been tested for sciatica. We aimed to investigate the c... Read More about Stratified care versus usual care for management of patients presenting with sciatica in primary care (SCOPiC): a randomised controlled trial.

Risk factors for non-specific neck pain in young adults. A systematic review. (2020)
Journal Article
Dunn. (2020). Risk factors for non-specific neck pain in young adults. A systematic review. BMC Musculoskeletal Disorders, https://doi.org/10.1186/s12891-020-03379-y

BACKGROUND: Young adulthood is a sensitive period of life where development of musculoskeletal neck pain may be established and impact future health. The objective of this systematic review was to investigate risk factors for non-specific neck pain i... Read More about Risk factors for non-specific neck pain in young adults. A systematic review..

Stratified primary care versus non-stratified care for musculoskeletal pain: findings from the STarT MSK feasibility and pilot cluster randomized controlled trial (2020)
Journal Article
Hill, J., Garvin, S., Chen, Y., Cooper, V., Wathall, S., Saunders, B., Lewis, A. M., Protheroe, J., Chudyk, A., Dunn, K., Hay, E., Van Der Windt, D., Mallen, C., & Foster, N. E. (2020). Stratified primary care versus non-stratified care for musculoskeletal pain: findings from the STarT MSK feasibility and pilot cluster randomized controlled trial. BMC Family Practice, 21, Article 30. https://doi.org/10.1186/s12875-019-1074-9

Background: Musculoskeletal (MSK) pain from the five most common presentations to primary care (back, neck, shoulder, knee or multi-site pain), where the majority of patients are managed, is a costly global health challenge. At present, first-line de... Read More about Stratified primary care versus non-stratified care for musculoskeletal pain: findings from the STarT MSK feasibility and pilot cluster randomized controlled trial.

Sleep problems and psychological symptoms as predictors of musculoskeletal conditions in children and adolescents. (2019)
Journal Article
Andreucci, A., Campbell, P., Dunn, K., Richardson, E., & Chen, Y. (2020). Sleep problems and psychological symptoms as predictors of musculoskeletal conditions in children and adolescents. European Journal of Pain, 24(2), 354-363. https://doi.org/10.1002/ejp.1491

BACKGROUND: Population-based studies show that sleep problems and psychological symptoms may increase the risk of musculoskeletal pain onset in children / adolescents. However, there is no evidence of these associations within primary care settings,... Read More about Sleep problems and psychological symptoms as predictors of musculoskeletal conditions in children and adolescents..

Risk factors for episodes of back pain in emerging adults. A systematic review (2019)
Journal Article
Elin Øiestad, B., Hilde, G., Therese Tveter, A., Peat, G. G., Thomas, M. J., Dunn, K. M., & Grotle, M. (2020). Risk factors for episodes of back pain in emerging adults. A systematic review. European Journal of Pain, 24(1), 19-38. https://doi.org/10.1002/ejp.1474

BACKGROUND AND OBJECTIVE: The transition from adolescence to adulthood is a sensitive period in life for health outcomes, including back pain. The objective was to synthesize evidence on risk factors for new episodes of back pain in emerging adults (... Read More about Risk factors for episodes of back pain in emerging adults. A systematic review.

Risk of adverse events in patients prescribed long-term opioids: a cohort study in the UK Clinical Practice Research Datalink (2019)
Journal Article
Bedson, J., Chen, Y., Ashworth, J., Hayward, R. A., Dunn, K. M., & Jordan, K. P. (2019). Risk of adverse events in patients prescribed long-term opioids: a cohort study in the UK Clinical Practice Research Datalink. European Journal of Pain, 23(5), 908-922. https://doi.org/10.1002/ejp.1357

Background
Long-term opioid prescribing for musculoskeletal pain is controversial due to uncertainty regarding effectiveness and safety. This study examined the risks of a range of adverse events in a large cohort of patients prescribed long-term op... Read More about Risk of adverse events in patients prescribed long-term opioids: a cohort study in the UK Clinical Practice Research Datalink.

Determining one-year trajectories of low back related leg pain in primary care patients: growth mixture modelling of a prospective cohort study (2018)
Journal Article
Dunn, & Stynes. (2018). Determining one-year trajectories of low back related leg pain in primary care patients: growth mixture modelling of a prospective cohort study. Arthritis Care and Research, 1840-1848. https://doi.org/10.1002/acr.23556

OBJECTIVE
The clinical presentation and outcome of patients with back and leg pain in primary care are heterogeneous and may be better understood by identification of homogeneous and clinically meaningful subgroups. Subgroups of patients with differ... Read More about Determining one-year trajectories of low back related leg pain in primary care patients: growth mixture modelling of a prospective cohort study.

Increased risk of reproductive dysfunction in women prescribed long-term opioids for musculoskeletal pain: a matched cohort study in the Clinical Practice Research Datalink. (2018)
Journal Article
Dunn. (2018). Increased risk of reproductive dysfunction in women prescribed long-term opioids for musculoskeletal pain: a matched cohort study in the Clinical Practice Research Datalink. European Journal of Pain, 1701-1708. https://doi.org/10.1002/ejp.1256

BACKGROUND: One fifth of primary care attendees suffer chronic non-cancer pain, with musculoskeletal conditions the leading cause. 12% of patients with chronic non-cancer pain are prescribed strong opioids. Evidence suggests long-term opioid use is r... Read More about Increased risk of reproductive dysfunction in women prescribed long-term opioids for musculoskeletal pain: a matched cohort study in the Clinical Practice Research Datalink..

Epidemiology of paediatric presentations with musculoskeletal problems in primary care. (2018)
Journal Article
Protheroe, & Dunn. (2018). Epidemiology of paediatric presentations with musculoskeletal problems in primary care. BMC Musculoskeletal Disorders, 40 - ?. https://doi.org/10.1186/s12891-018-1952-7

BACKGROUND: Musculoskeletal disease is a common cause of morbidity, but there is a paucity of musculoskeletal research focusing on paediatric populations, particularly in primary care settings. In particular, there is limited information on populatio... Read More about Epidemiology of paediatric presentations with musculoskeletal problems in primary care..

Trajectories and predictors of the long-term course of low back pain: cohort study with 5-year follow-up (2018)
Journal Article
Jordan, K., Dunn, K., Strauss, V., Foster, N., Chen, Y., & Campbell, P. (2018). Trajectories and predictors of the long-term course of low back pain: cohort study with 5-year follow-up. PAIN, 252-260. https://doi.org/10.1097/j.pain.0000000000001097

Low back pain (LBP) is a major health challenge globally. Research has identified common trajectories of pain over time. We aimed to investigate whether trajectories described in one primary care cohort can be confirmed in another, and to determine t... Read More about Trajectories and predictors of the long-term course of low back pain: cohort study with 5-year follow-up.

Novel approach to characterising individuals with low back-related leg pain: cluster identification with latent class analysis and 12-month follow-up. (2018)
Journal Article
Stynes, S., Konstantinou, K., Ogollah, R., Hay, E. M., & Dunn, K. M. (2018). Novel approach to characterising individuals with low back-related leg pain: cluster identification with latent class analysis and 12-month follow-up. PAIN, 159(4), https://doi.org/10.1097/j.pain.0000000000001147

Traditionally, low back-related leg pain (LBLP) is diagnosed clinically as referred leg pain or sciatica (nerve root involvement). However, within the spectrum of LBLP, we hypothesised that there may be other unrecognised patient subgroups. This stud... Read More about Novel approach to characterising individuals with low back-related leg pain: cluster identification with latent class analysis and 12-month follow-up..

Prognosis of sciatica and back-related leg pain in primary care: the ATLAS cohort (2017)
Journal Article
Konstantinou, K., Dunn, K., Ogollah, R., Lewis, M., Van Der Windt, D., Hay, E., & Study Team, A. (2017). Prognosis of sciatica and back-related leg pain in primary care: the ATLAS cohort. Spine Journal, 1030-1040. https://doi.org/10.1016/j.spinee.2017.10.071

Background Context
Evidence is lacking on the prognosis and prognostic factors of back-related leg pain and sciatica in patients seeing their primary care physicians. This evidence could guide timely appropriate treatment and referral decisions.... Read More about Prognosis of sciatica and back-related leg pain in primary care: the ATLAS cohort.