Alteration of the expression of sirtuins and var genes by heat shock in the malaria parasite Plasmodium falciparum (2022)
Journal Article
Anagu, L. O., Hulse, D. R., Horrocks, P. D., & Chakravorty, S. J. (2022). Alteration of the expression of sirtuins and var genes by heat shock in the malaria parasite Plasmodium falciparum. Molecular and Biochemical Parasitology, 111458 - 111458. https://doi.org/10.1016/j.molbiopara.2022.111458

Background
In Plasmodium falciparum the monoallelic expression of var virulence genes is regulated through epigenetic mechanisms. A study in the Gambia showed that an increase in var gene expression is associated with fever, high blood lactate with... Read More about Alteration of the expression of sirtuins and var genes by heat shock in the malaria parasite Plasmodium falciparum.